amitriptyline and sodium bicarbonate

amitriptyline has been researched along with sodium bicarbonate in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (28.00)	18.7374
1990's	3 (12.00)	18.2507
2000's	6 (24.00)	29.6817
2010's	8 (32.00)	24.3611
2020's	1 (4.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Calderon, J; Gillette, P; O'Riordan, W; Stennes, RL	1
Burnham, L; Finley, PR; Levitt, MA; Owens, SM; Sullivan, JB	1
Baker, PB; Dalsey, WC; Hedges, JR; Otten, EJ; Syverud, SA; Tasset, JJ	1
Kärkkäinen, S; Neuvonen, PJ	1
Jhamandas, V; Sasyniuk, BI; Valois, M	1
Jhamandas, V; Sasyniuk, BI	1
Mittleman, M; Nattel, S	1
Dequin, PF; Furet, Y; Lanotte, R; Legras, A; Perrotin, D	1
Abrahamsson, J; Knudsen, K	1
Brady, WJ; Harrigan, RA	1
Deegan, C; O'Brien, K	1
Dargan, P; Greene, S; Jones, A; O'Connor, N; Wyncoll, D	1
Bebarta, VS; Waksman, JC	2
Algren, DA; Sutter, ME	1
Chan, HY; Chan, YC; Lau, FL	1
Clement, A; Lowry, JA; Raney, JJ; Wasserman, GS	1
Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL	1
James, D; Ramasubbu, B; Sandilands, EA; Scurr, A	1
Cave, G; Chapman, R; Davies, P; Harvey, M; Wu, Z	1
Hori, K; Kuno, M; Matsuura, T; Mori, T; Nishikawa, K; Tsujikawa, S	1
Ambati, S; Butt, K	1
Kazama, I; Muto, M; Nagano, A; Shida, J	1

Reviews

1 review(s) available for amitriptyline and sodium bicarbonate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for amitriptyline and sodium bicarbonate

Article	Year
Pharmacokinetics of amitriptyline influenced by oral charcoal and urine pH. International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:6 Topics: Administration, Oral; Adult; Amitriptyline; Ammonium Chloride; Bicarbonates; Charcoal; Female; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kidney; Kinetics; Male; Nortriptyline; Random Allocation; Sodium; Sodium Bicarbonate	1986

Article

Year

Pharmacokinetics of amitriptyline influenced by oral charcoal and urine pH.

International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:6

Topics: Administration, Oral; Adult; Amitriptyline; Ammonium Chloride; Bicarbonates; Charcoal; Female; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kidney; Kinetics; Male; Nortriptyline; Random Allocation; Sodium; Sodium Bicarbonate

1986

Other Studies

23 other study(ies) available for amitriptyline and sodium bicarbonate

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Overdose of cyclobenzaprine, the tricyclic muscle relaxant. Annals of emergency medicine, 1986, Volume: 15, Issue:5 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bicarbonates; Charcoal; Emergencies; Female; Humans; Ipecac; Muscle Relaxants, Central; Sodium; Sodium Bicarbonate; Therapeutic Irrigation	1986
Amitriptyline plasma protein binding: effect of plasma pH and relevance to clinical overdose. The American journal of emergency medicine, 1986, Volume: 4, Issue:2 Topics: Amitriptyline; Arrhythmias, Cardiac; Bicarbonates; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ions; Protein Binding; Sodium; Sodium Bicarbonate	1986
Bicarbonate therapy for the cardiovascular toxicity of amitriptyline in an animal model. The Journal of emergency medicine, 1985, Volume: 3, Issue:4 Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Bicarbonates; Blood Gas Analysis; Dogs; Electrocardiography; Heart Rate; Sodium; Sodium Bicarbonate	1985
Experimental amitriptyline intoxication: treatment of cardiac toxicity with sodium bicarbonate. Annals of emergency medicine, 1986, Volume: 15, Issue:9 Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Bicarbonates; Dogs; Electrocardiography; Heart Conduction System; Propranolol; Sodium; Sodium Bicarbonate; Tachycardia	1986
Mechanism of reversal of toxic effects of amitriptyline on cardiac Purkinje fibers by sodium bicarbonate. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2 Topics: Action Potentials; Amitriptyline; Animals; Bicarbonates; Dogs; Electric Stimulation; Extracellular Space; Female; Heart Conduction System; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Membrane Potentials; Purkinje Fibers; Sodium; Sodium Bicarbonate; Time Factors	1984
Treatment of ventricular tachyarrhythmias resulting from amitriptyline toxicity in dogs. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2 Topics: Amitriptyline; Animals; Bicarbonates; Dogs; Female; Hyperventilation; Lidocaine; Male; Saline Solution, Hypertonic; Sodium Bicarbonate; Tachycardia	1984
[Molar sodium bicarbonate and adrenaline combination during severe tricyclic intoxication in a gastrectomized woman]. Presse medicale (Paris, France : 1983), 1994, Mar-19, Volume: 23, Issue:11 Topics: Adult; Amitriptyline; Drug Therapy, Combination; Epinephrine; Female; Gastrectomy; Humans; Infusions, Intravenous; Sodium Bicarbonate; Suicide, Attempted	1994
Epinephrine and sodium bicarbonate independently and additively increase survival in experimental amitriptyline poisoning. Critical care medicine, 1997, Volume: 25, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Disease Models, Animal; Drug Combinations; Electrolytes; Epinephrine; Hemodynamics; Humans; Male; Norepinephrine; Poisoning; Rats; Rats, Sprague-Dawley; Sodium Bicarbonate; Survival Rate; Sympathomimetics	1997
ECG abnormalities in tricyclic antidepressant ingestion. The American journal of emergency medicine, 1999, Volume: 17, Issue:4 Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antidotes; Arrhythmia, Sinus; Charcoal; Cholinergic Antagonists; Doxepin; Drug Overdose; Electrocardiography; Female; Humans; Point-of-Care Systems; Sodium Bicarbonate; Sodium Channel Blockers; Sorption Detoxification; Tachycardia	1999
Amitriptyline poisoning in a 2-year old. Paediatric anaesthesia, 2006, Volume: 16, Issue:2 Topics: Adrenergic beta-Agonists; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Blood Gas Analysis; Cardiopulmonary Resuscitation; Child, Preschool; Coma; Drug Overdose; Heart Arrest; Humans; Hypnotics and Sedatives; Kidney; Magnesium Sulfate; Male; Seizures; Sodium Bicarbonate; Time Factors; Treatment Outcome; Vasodilator Agents	2006
Prolonged clinical effects in modified-release amitriptyline poisoning. Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:1 Topics: Acidosis; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Central Nervous System Diseases; Charcoal; Delayed-Action Preparations; Female; Humans; Injections, Intravenous; Poisoning; Sodium Bicarbonate; Treatment Outcome	2006
Amitriptyline-induced Brugada pattern fails to respond to sodium bicarbonate. Clinical toxicology (Philadelphia, Pa.), 2007, Volume: 45, Issue:2 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brugada Syndrome; Drug Overdose; Electrocardiography; Humans; Male; Middle Aged; Sodium Bicarbonate; Sodium Channels; Treatment Failure	2007
Reply to: "Amitriptyline-induced Brugada pattern fails to respond to sodium bicarbonate". Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brugada Syndrome; Electrocardiography; Humans; Saline Solution, Hypertonic; Sodium Bicarbonate	2008
Treatment of tricyclic antidepressant cardiac toxicity. Pediatric emergency care, 2008, Volume: 24, Issue:3 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child, Preschool; Humans; Hydrogen-Ion Concentration; Lidocaine; Magnesium Sulfate; Male; Sodium Bicarbonate; Tachycardia, Ventricular; Treatment Outcome; Turkey	2008
Reversal of Brugada electrocardiographic pattern with sodium bicarbonate solution after amitriptyline overdose. Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:9 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Brugada Syndrome; Drug Overdose; Electrocardiography; Humans; Male; Sodium Bicarbonate; Suicide	2008
Chronic amitriptyline overdose in a child. Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:5 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Drug Overdose; Electrocardiography; Female; Humans; Nortriptyline; Sleep Wake Disorders; Sodium Bicarbonate; Status Epilepticus; Treatment Outcome	2012
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6 Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocardiography; Epilepsy; Female; Heart Arrest; Humans; Lacosamide; Levetiracetam; Piracetam; Risk Factors; Sodium Bicarbonate; Sodium Channel Blockers; Sodium Channels; Suicide, Attempted; Tachycardia, Ventricular; Treatment Outcome	2015
Serum alkalinisation is the cornerstone of treatment for amitriptyline poisoning. BMJ case reports, 2016, Apr-11, Volume: 2016 Topics: Adult; Amitriptyline; Antacids; Antidepressive Agents, Tricyclic; Drug Overdose; Female; Humans; Sodium Bicarbonate; Tachycardia	2016
Liposome supported peritoneal dialysis in rat amitriptyline exposure with and without intravenous lipid emulsion. Journal of liposome research, 2019, Volume: 29, Issue:2 Topics: Administration, Intravenous; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Fat Emulsions, Intravenous; Female; Hydrogen-Ion Concentration; Liposomes; Peritoneal Dialysis; Peritoneum; Rats, Sprague-Dawley; Regional Blood Flow; Sodium Bicarbonate	2019
Superior Efficacy of Lipid Emulsion Infusion Over Serum Alkalinization in Reversing Amitriptyline-Induced Cardiotoxicity in Guinea Pig. Anesthesia and analgesia, 2018, Volume: 126, Issue:4 Topics: Acid-Base Equilibrium; Action Potentials; Alkalies; Amitriptyline; Animals; Arterial Pressure; Cardiotoxicity; Disease Models, Animal; Emulsions; Guinea Pigs; Heart Diseases; Heart Rate; Hydrogen-Ion Concentration; Infusions, Intravenous; Isolated Heart Preparation; Kinetics; Male; Myocytes, Cardiac; Phospholipids; Recovery of Function; Sodium; Sodium Bicarbonate; Soybean Oil; Ventricular Function, Left	2018
A Peculiar Wide Complex Tachycardia. Circulation, 2019, 03-12, Volume: 139, Issue:11 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cardiotoxicity; Drug Overdose; Electrocardiography; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Predictive Value of Tests; Sodium Bicarbonate; Tachycardia, Ventricular	2019
Amitriptyline intoxication in bullfrogs causes widening of QRS complexes in electrocardiogram. The Journal of veterinary medical science, 2023, Feb-01, Volume: 85, Issue:2 Topics: Amitriptyline; Animals; Electrocardiography; Heart; Rana catesbeiana; Sodium Bicarbonate	2023