amitriptyline and sibutramine

amitriptyline has been researched along with sibutramine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buckett, WR; Butler, SA; Heal, DJ; Hurst, EM1
Devaney, N; King, DJ1
Gray, AM; Sewell, RD; Spencer, PS1
Gray, AM; Pache, DM; Sewell, RD1
Deslandes, PN; Pache, DM; Sewell, RD; Subhan, F1

Reviews

1 review(s) available for amitriptyline and sibutramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for amitriptyline and sibutramine

ArticleYear
Clinical pharmacology of sibutramine hydrochloride (BTS 54524), a new antidepressant, in healthy volunteers.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:5

    Topics: Adult; Amitriptyline; Antidepressive Agents; Blood Pressure; Cyclobutanes; Double-Blind Method; Drug Evaluation; Heart Rate; Hemodynamics; Humans; Male; Psychomotor Performance; Random Allocation; Sleep Stages; Time Factors

1988

Other Studies

7 other study(ies) available for amitriptyline and sibutramine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi

2010
Antidepressant treatments, including sibutramine hydrochloride and electroconvulsive shock, decrease beta 1- but not beta 2-adrenoceptors in rat cortex.
    Journal of neurochemistry, 1989, Volume: 53, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Cerebral Cortex; Clenbuterol; Cyclobutanes; Desipramine; Dihydroalprenolol; Electroshock; Kinetics; Male; Rats; Receptors, Adrenergic, beta; Reference Values; Tranylcypromine; Zimeldine

1989
The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds.
    British journal of pharmacology, 1998, Volume: 124, Issue:4

    Topics: Abdominal Muscles; Acetic Acid; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Male; Maprotiline; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Neurotransmitter Uptake Inhibitors; Opioid Peptides; Pain Measurement; Paroxetine; Protease Inhibitors; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Thiorphan

1998
Do alpha2-adrenoceptors play an integral role in the antinociceptive mechanism of action of antidepressant compounds?
    European journal of pharmacology, 1999, Aug-06, Volume: 378, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Drug Interactions; Male; Maprotiline; Mice; Norepinephrine; Pain Measurement; Paroxetine; Random Allocation; Receptors, Adrenergic; Selective Serotonin Reuptake Inhibitors

1999
Do antidepressants affect motivation in conditioned place preference?
    European journal of pharmacology, 2000, Nov-24, Volume: 408, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclobutanes; Cyclohexanols; Dose-Response Relationship, Drug; Fluoxetine; Male; Motivation; Norepinephrine; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Venlafaxine Hydrochloride

2000