amitriptyline has been researched along with risperidone in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 15 (41.67) | 29.6817 |
| 2010's | 13 (36.11) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Keserü, GM | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Kenny, PW; Toulmin, A; Wood, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Eikelmann, B; Konrad, C; Schormair, C; Telger, K | 1 |
| Blom, MW; Huang, ML; Levron, JC; Snyman, JR; Sommers, DK; van Wyk, M | 1 |
| Yong, JN | 1 |
| Benkert, O; Hillert, A; Müller, MJ; Müller-Siecheneder, F; Szegedi, A; Wetzel, H | 1 |
| Caley, CF | 1 |
| Kootstra-Ros, JE; van Baalen-Benedek, EH; van der Weide, J | 1 |
| Dickenson, ER; Drewes, JE; Khan, SJ; McDonald, JA; Stevens-Garmon, J | 1 |
| Arnold, LE; Han, JC; Hellings, JA | 1 |
| Deckert, J; Hommers, LG; Menke, A; Samanski, L; Scherf-Clavel, M; Unterecker, S | 1 |
| Bernardo, CO; Gonzalez-Chica, DA; Jureidini, J; Klau, J; Raven, M | 1 |
| Deckert, J; Eckert, A; Frantz, A; Hahn, M; Reif, A; Scherf-Clavel, M; Unterecker, S; Weber, H | 1 |
2 review(s) available for amitriptyline and risperidone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Dopamine antagonists for treatment resistance in autism spectrum disorders: review and focus on BDNF stimulators loxapine and amitriptyline.
Topics: Adolescent; Adult; Amitriptyline; Antipsychotic Agents; Aripiprazole; Autism Spectrum Disorder; Brain-Derived Neurotrophic Factor; Child; Dopamine Antagonists; Humans; Irritable Mood; Loxapine; Risperidone | 2017 |
2 trial(s) available for amitriptyline and risperidone
| Article | Year |
|---|---|
Lack of effect of amitriptyline on risperidone pharmacokinetics in schizophrenic patients.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Area Under Curve; Biotransformation; Delayed-Action Preparations; Drug Interactions; Female; Half-Life; Humans; Male; Psychiatric Status Rating Scales; Risperidone; Schizophrenia | 1997 |
Risperidone versus haloperidol and amitriptyline in the treatment of patients with a combined psychotic and depressive syndrome.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone | 1998 |
32 other study(ies) available for amitriptyline and risperidone
| Article | Year |
|---|---|
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Toward prediction of alkane/water partition coefficients.
Topics: Alkanes; Central Nervous System; Molecular Structure; Static Electricity; Surface Properties; Water | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Risperidone after clozapine in therapy refractory schizoaffective psychosis--a case report].
Topics: Adult; Amitriptyline; Antipsychotic Agents; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Prognosis; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Treatment Outcome | 1997 |
Nefazodone and neurotoxicity.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Carbamazepine; Cytochrome P-450 CYP2D6; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Risperidone; Triazoles | 1997 |
Extrapyramidal reactions from concurrent SSRI and atypical antipsychotic use.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Fluoxetine; Humans; Risperidone; Selective Serotonin Reuptake Inhibitors | 1998 |
Metabolic ratios of psychotropics as indication of cytochrome P450 2D6/2C19 genotype.
Topics: Alleles; Amitriptyline; Aryl Hydrocarbon Hydroxylases; Cyclohexanols; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Desvenlafaxine Succinate; Enzyme Activation; Gene Frequency; Genotype; Humans; Metabolic Clearance Rate; Mixed Function Oxygenases; Psychotropic Drugs; Risperidone; Venlafaxine Hydrochloride | 2005 |
Sorption of emerging trace organic compounds onto wastewater sludge solids.
Topics: Adsorption; Amitriptyline; Clozapine; Cosmetics; Household Products; Hydroxyzine; Organic Chemicals; Pharmaceutical Preparations; Risperidone; Sewage; Verapamil; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Female; Glucuronosyltransferase; Humans; Male; Middle Aged; Mirtazapine; Nortriptyline; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Smoking; Venlafaxine Hydrochloride | 2019 |
Trends in prescription of psychotropic medications to children and adolescents in Australian primary care from 2011 to 2018.
Topics: Adolescent; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Australia; Benzodiazepines; Child; Child, Preschool; Drug Prescriptions; Female; Fluoxetine; Humans; Hypnotics and Sedatives; Male; Melatonin; Primary Health Care; Psychotropic Drugs; Quetiapine Fumarate; Retrospective Studies; Risperidone | 2022 |
Effect of CYP2D6 pharmacogenetic phenotype and phenoconversion on serum concentrations of antidepressants and antipsychotics: a retrospective cohort study.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Genotype; Humans; Pharmacogenetics; Phenotype; Retrospective Studies; Risperidone; Venlafaxine Hydrochloride | 2023 |