amitriptyline and quinine

amitriptyline has been researched along with quinine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199011 (39.29)18.7374
1990's0 (0.00)18.2507
2000's9 (32.14)29.6817
2010's8 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Moffat, AC1
Beavis, AD1
Cadden, JJ; Feigelson, EB1
Geisler, A; Thomsen, K2
Bastos, ML; Jukofsky, D; Mulé, SJ1
Bwibo, NO1
Geisler, A1
Clèdes, J; Favarel-Garrigues, JC; Potaux, L; Sagardiluz, J1
Andersen, E; Geisler, A; Vedso, S1
Ferguson, PD; Jiang, Z; Smith, NW; Taylor, MR1

Reviews

1 review(s) available for amitriptyline and quinine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for amitriptyline and quinine

ArticleYear
[Failure to adhere to prescribed drug treatment. An investigation with labelled tablets].
    Ugeskrift for laeger, 1973, Sep-03, Volume: 135, Issue:36

    Topics: Adult; Amitriptyline; Chlorprothixene; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Prescriptions; Ethanol; Female; Humans; Male; Mental Disorders; Middle Aged; Outpatient Clinics, Hospital; Piperazines; Placebos; Psychiatric Department, Hospital; Quinine

1973
Drug defaulting estimated by the use of a drug marker.
    Current medical research and opinion, 1973, Volume: 1, Issue:10

    Topics: Adult; Amitriptyline; Attitude to Health; Chlorprothixene; Chromatography, Thin Layer; Ethanol; Female; Hospitalization; Humans; Intellectual Disability; Male; Mental Disorders; Middle Aged; Neurotic Disorders; Outpatient Clinics, Hospital; Personality Disorders; Piperazines; Placebos; Psychotic Disorders; Quinine; Self Medication; Substance-Related Disorders; Thioxanthenes; Tranquilizing Agents

1973
[Failure to observe the treatment as a source of error in assessing the effect of an antidepressant (amitriptyline) on reactive depressions].
    Nordisk psykiatrisk tidsskrift. Nordic journal of psychiatry, 1970, Volume: 24, Issue:3

    Topics: Adjustment Disorders; Adult; Amitriptyline; Depression; Female; Humans; Male; Middle Aged; Placebos; Quinine

1970

Other Studies

24 other study(ies) available for amitriptyline and quinine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The standardisation of thin-layer chromatographic systems for the identification of basic drugs.
    Journal of chromatography, 1975, Jul-16, Volume: 110, Issue:2

    Topics: Amitriptyline; Amphetamine; Caffeine; Chromatography, Thin Layer; Codeine; Hydrogen-Ion Concentration; Lidocaine; Meperidine; Pharmaceutical Preparations; Quinine; Silicon Dioxide; Solvents; Strychnine

1975
On the inhibition of the mitochondrial inner membrane anion uniporter by cationic amphiphiles and other drugs.
    The Journal of biological chemistry, 1989, Jan-25, Volume: 264, Issue:3

    Topics: Algorithms; Amiodarone; Amitriptyline; Animals; Anion Transport Proteins; Benzodiazepinones; Calcimycin; Carrier Proteins; Hydrogen-Ion Concentration; Imipramine; Intracellular Membranes; Mitochondria; Propranolol; Quinine

1989
Changing patterns of drug abuse in New York City.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders

1974
Routine identification of drugs of abuse in human urine. 3. Differential elution of the XAD-2 resin.
    Journal of chromatography, 1973, Jun-27, Volume: 81, Issue:1

    Topics: Amitriptyline; Amphetamine; Barbiturates; Chromatography, Thin Layer; Dextropropoxyphene; Humans; Hydrogen-Ion Concentration; Methods; Pharmaceutical Preparations; Phenobarbital; Phenylpropanolamine; Phenytoin; Quinine; Resins, Plant; Solvents; Substance-Related Disorders

1973
Accidental poisoning in children in Uganda.
    British medical journal, 1969, Dec-06, Volume: 4, Issue:5683

    Topics: Amitriptyline; Aspirin; Barbiturates; Child; Child, Preschool; Chloroquine; Codeine; Dapsone; Diazepam; Ethanol; Female; Humans; Infant; Iron; Kerosene; Male; Pesticides; Poisoning; Quinine; Tetrachloroethylene; Uganda

1969
[Cardiac complications in acute poisoning].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1967, Volume: 144, Issue:7

    Topics: Adolescent; Adult; Amitriptyline; Arrhythmias, Cardiac; Child; Child, Preschool; Chloroquine; Digitalis Glycosides; Electrocardiography; Heart; Humans; Imipramine; Middle Aged; Poisoning; Quinine

1967
[The cooperation of patients with depression during drug treatment. A study using guinine as a tracer].
    Ugeskrift for laeger, 1968, Oct-24, Volume: 130, Issue:43

    Topics: Adolescent; Adult; Amitriptyline; Attitude to Health; Depression; Drug Therapy; Female; Humans; Male; Middle Aged; Patients; Quinine

1968
Mixed-mode reversed-phase and ion-exchange monolithic columns for micro-HPLC.
    Journal of separation science, 2008, Volume: 31, Issue:15

    Topics: Acrylates; Amitriptyline; Aniline Compounds; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diltiazem; Hydrogen-Ion Concentration; Ketones; Methacrylates; Microchemistry; Molecular Structure; Particle Size; Phenols; Polycyclic Aromatic Hydrocarbons; Polymers; Porosity; Pyrazines; Quinine; Reproducibility of Results; Sensitivity and Specificity; Stearates; Surface Properties; Time Factors; Verapamil

2008