amitriptyline and propranolol

amitriptyline has been researched along with propranolol in 120 studies

Research

Studies (120)

Timeframe	Studies, this research(%)	All Research%
pre-1990	47 (39.17)	18.7374
1990's	12 (10.00)	18.2507
2000's	27 (22.50)	29.6817
2010's	29 (24.17)	24.3611
2020's	5 (4.17)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Blake, JF; Curatolo, WJ; Lombardo, F	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S	1
Klaus, D; Klumpp, F; Lemke, R; Zehner, J	1
Holan, J; Kubisz, P; Stránska, M; Suranová, J	1
Delini-Stula, A; Radeke, E; Vassout, A	1
Burgess, CD; Turner, P; Wadsworth, J	1
Fludder, JM; Leonard, BE	1
Bahler, A; Pincus, J; Schneider, RR; Stimmel, B	1
Banaszkiewicz, W; Grzymislawska, I; Mrozikiewica, A	1
Bergström, J; Castenfors, J; Thorstrand, C	1
Kikuchi, A; Kim, YS; Takai, Y	1
Goldberg, J; Stern, BJ; Weiss, HD	1
Adachi, JD; Guyatt, GH; Jaeschke, R; Keller, JL; Newhouse, MT; Rosenbloom, D	1
Beavis, AD	1
Bousser, MG; Massiou, H	1
Jhamandas, V; Sasyniuk, BI; Valois, M	1
Crews, FT; Scott, JA	1
Andrews, P; Harder, A; Thomas, H	1
Hassanein, RS; Hurwitz, A; Kodanaz, HA; Mason, J; Preskorn, SH; Ziegler, DK	1
Diamond, S; Prager, J	1
Kellhammer, U; Pfaffenrath, V; Pöllmann, W	1
Gunderson, CH	1
Debuch, H; Harder, A	1
Kodama, T; Matsukado, Y; Shimizu, H; Suzuki, T; Tanaka, S	1
Garattini, S; Jori, A; Paglialunga, S	1
Thorstrand, C	1
König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P	1
Lauer, RM; Mueller, S; Roberts, RJ	1
Ziegler, DK	2
Lagerquist, B; Morgan, GM; Stone, CA; Torchiana, ML; Wenger, HC	1
Oates, JA; Shand, DG	1
Born, GV; Smith, JB	1
Delius, L	1
Brody, TM; McNeill, JH	1
Jacobsen, JR	1
Scriabine, A	1
Nymark, M; Rasmussen, J	1
Aronow, WS; Tobis, JM	1
Olsnes, S; Sandvig, K; Sundan, A	1
Damasio, H	1
Jay, GW; Mead, T; Renelli, D	1
Baldrati, A; Cortelli, P; D'Alessandro, R; De Carolis, P; Lugaresi, E; Sacquegna, T; Santucci, M	1
Harris, DB; Stiff, JL	1
Marsden, CA; Stolz, JF	2
Pentel, P; Peterson, CD	1
Mathew, NT	1
Fozard, JR	1
Raskin, NH; Schwartz, RK	1
Beek, D; Kenakin, TP	1
Hassanein, R; Hurwitz, A; Preskorn, S; Seim, J; Ziegler, DK	1
Hashimoto, H; Ikeda, Y; Nakashima, M; Nishimoto, M; Shimazu, Y; Umemura, K	1
Castronovo, V; Ferini-Strambi, L; Montorsi, F; Oldani, A; Rigatti, P; Smirne, S; Zucconi, M	1
Gilkey, SJ; Ramadan, NM; Schultz, LL	1
de Souza, JA; Jevoux, Cda C; Moreira Filho, PF	1
Lu, W; McCarley, TD; Shamsi, SA; Warner, IM	1
Fujiseki, Y; Inagaki, C; Kinoshita, T; Okugawa, G; Omori, K; Suzukawa, J	1
Landwojtowicz, E; Seelig, A	1
Fisk, R; Lu, Z; Mallet, CR; Mazzeo, JR; Neue, UD	1
Chapman, KE; Kelly, PA; Lai, M; McCormick, JA; Seckl, JR; Yau, JL	1
Mayer, J; McDiarmid, T; Spry, H; Stanton, RN	1
Amelin, AV; Ignatov, IuD; Skoromets, AA	1
Doig, K; Eliasziw, M; Kiss, ZH; Ranawaya, R; Suchowersky, O	1
Mannix, LK	1
Evans, RW; Láinez, MJ; Leira, R; Pascual, J	1
Dainese, F; Maggioni, F; Mainardi, F; Ruffatti, S; Zanchin, G	1
Dehghani, SM; Fallahi, GH; Haghighat, M; Nejabat, M; Rafie, SM	1
Quimbo, RM; Rupnow, MF; Wertz, DA; Yaldo, AZ	1
Ruangsuwan, S; Sri-udomkajorn, S	1
Akgun Arici, MA; Demir, O; Gidener, S; Hocaoglu Aksay, N; Kalkan, S; Tuncok, Y	1
Cansu, A; Gulbahar, O; Hirfanoglu, T; Serdaroglu, A	1
Firnhaber, JM; Rickett, K	1
Chang, FY; Liao, KY; Wu, LT; Wu, TC	1
Bendtsen, L	1
Dlugatch, Y; Eidlitz-Markus, T; Goldberg-Stern, H; Haimi-Cohen, Y; Zeharia, A	1
Beule, J; Dippold, W; Keller, K; Pfnür, M; Scholz, M	1
Ahmed, S; Alam, MN; Ali, MA; Battacharjee, M; Dey, SK; Israil, A; Miah, AH; Mondal, G; Rahman, KM; Uddin, MJ; Uddin, MS	1
Macedo, CR; Macedo, EC; Prado, GF; Silva, AB; Torloni, MR	1
Cainelli, F; Mojela, K; Molobe, LT; Shifa, J; Silava, C; Vento, S	1
Jarasvaraparn, C; Lertudomphonwanit, C; Tanpowpong, P; Treepongkaruna, S	1
Chisholm, D; Linde, M; Steiner, TJ	1
Ak, S; Atasayar, G; Can, FE; Cecener, G; Egeli, U; Eryilmaz, IE; Karli, N; Taskapilioglu, O; Tezcan, G; Tunca, B; Yildirim, O; Zarifoglu, M	1
Haimi-Cohen, Y; Markus, TE; Moad, B; Zeharia, A	1
He, A; Li, C; Song, D; Zhang, L	1
Acharya, K; Georgiou, A; Gosling, M; Le Fevre, P	1
May, A	1
Kapoor, Y; Kumar, A; Sharma, R	1
Álvarez-Morujo de Sande, MG; Bécares-Martínez, C; Domènech-Vadillo, E; Domínguez-Durán, E; González-Aguado, R; Guerra-Jiménez, G; Montilla-Ibáñez, MA	1
Chen, F; Gao, H; Guo, R; Liu, H; Sun, P; Wang, B; Wang, S; Yang, K	1
Earnest, R; Goodman, MD; McGlone, E; Morris, MC; Singer, KE; Stevens-Topie, S; Wallen, TE	1

Reviews

15 review(s) available for amitriptyline and propranolol

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
An overview of the classification, causes, and treatment of headache. Hospital & community psychiatry, 1984, Volume: 35, Issue:3 Topics: Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Cerebrovascular Circulation; Dilatation, Pathologic; Electroencephalography; Epilepsy; Ergotamine; Female; Headache; Humans; Male; Methysergide; Migraine Disorders; Muscle Contraction; Platelet Aggregation; Propranolol; Relaxation Therapy	1984
Drug management of adult vascular headaches (migraine and cluster headache): Part II--Prevention and attacks. Iowa medicine : journal of the Iowa Medical Society, 1984, Volume: 74, Issue:12 Topics: Adult; Amitriptyline; Belladonna Alkaloids; Cluster Headache; Cyproheptadine; Drug Combinations; Ergotamine; Ergotamines; Female; Humans; Lithium; Lithium Carbonate; Male; Methysergide; Migraine Disorders; Monoamine Oxidase Inhibitors; Naproxen; Phenobarbital; Pregnancy; Pregnancy Complications; Propranolol; Vascular Headaches	1984
Basic mechanisms of antimigraine drugs. Advances in neurology, 1982, Volume: 33 Topics: Amitriptyline; Animals; Chlorpromazine; Humans; Methysergide; Metoclopramide; Migraine Disorders; Propranolol; Receptors, Serotonin; Serotonin Antagonists	1982
Migraine prophylactic drugs: proof of efficacy, utilization and cost. Cephalalgia : an international journal of headache, 1997, Volume: 17, Issue:2 Topics: Adult; Amitriptyline; Female; Humans; Male; Migraine Disorders; Propranolol; Verapamil	1997
Clinical inquiries. What medication best prevents migraine in children? The Journal of family practice, 2003, Volume: 52, Issue:10 Topics: Amitriptyline; Child; Evidence-Based Medicine; Humans; Migraine Disorders; Propranolol; Valproic Acid	2003
[Current views on migraine and anti-migraine preparations]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 2003, Issue:10 Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antidepressive Agents; Aza Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Clonidine; Fluoxetine; Humans; Imidazoles; Maprotiline; Methysergide; Migraine Disorders; Mutation; Pizotyline; Placebos; Propranolol; Research; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sympatholytics; Vasoconstrictor Agents	2003
Clinical advances in the preventive treatment of migraine. Acta neurologica Taiwanica, 2004, Volume: 13, Issue:4 Topics: Amitriptyline; Fructose; Humans; Migraine Disorders; Propranolol; Topiramate; Valproic Acid	2004
Clinical inquiries. What are the best prophylactic drugs for migraine? The Journal of family practice, 2009, Volume: 58, Issue:11 Topics: Adrenergic beta-Antagonists; Amitriptyline; Evidence-Based Medicine; Family Practice; Female; Fructose; Humans; Male; Migraine Disorders; Neuroprotective Agents; Pain Measurement; Practice Guidelines as Topic; Prognosis; Propranolol; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Severity of Illness Index; Timolol; Topiramate; Treatment Outcome	2009
[Cyclic vomiting syndrome (CVS) in adults - frequently overlooked?]. Zeitschrift fur Gastroenterologie, 2012, Volume: 50, Issue:7 Topics: Adult; Amitriptyline; Antiemetics; Humans; Hypnotics and Sedatives; Propranolol; Vomiting	2012
Pharmacotherapy for sleep bruxism. The Cochrane database of systematic reviews, 2014, Oct-23, Issue:10 Topics: Amitriptyline; Bromocriptine; Clonidine; Humans; Levodopa; Propranolol; Randomized Controlled Trials as Topic; Sleep Bruxism; Tryptophan	2014
Prevention of migraine attacks. First-choice treatments. Prescrire international, 2015, Volume: 24, Issue:157 Topics: Adrenergic beta-Antagonists; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Female; Humans; Migraine Disorders; Pregnancy; Pregnancy Complications; Propranolol; Risk Factors; Risk Reduction Behavior; Treatment Outcome; Valproic Acid	2015
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. The journal of headache and pain, 2017, Volume: 18, Issue:1 Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders; Nausea; Pre-Exposure Prophylaxis; Propranolol; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Valproic Acid	2017
Hints on Diagnosing and Treating Headache. Deutsches Arzteblatt international, 2018, 04-27, Volume: 115, Issue:17 Topics: Amitriptyline; Analgesics, Non-Narcotic; Antihypertensive Agents; Headache; Humans; Metoprolol; Migraine Disorders; Propranolol; Research Design; Tension-Type Headache; Trigeminal Autonomic Cephalalgias	2018

Trials

8 trial(s) available for amitriptyline and propranolol

Article	Year
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs. British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Double-Blind Method; Drug Interactions; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mianserin; Propranolol	1978
Migraine prophylaxis. A comparison of propranolol and amitriptyline. Archives of neurology, 1987, Volume: 44, Issue:5 Topics: Adult; Amitriptyline; Anxiety; Depression; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Propranolol; Psychological Tests	1987
Prophylaxis of migraine and mixed headache. A randomized controlled study. Headache, 1981, Volume: 21, Issue:3 Topics: Adult; Amitriptyline; Biofeedback, Psychology; Clinical Trials as Topic; Female; Headache; Humans; Male; Middle Aged; Propranolol; Random Allocation	1981
Propranolol and amitriptyline in prophylaxis of migraine. Pharmacokinetic and therapeutic effects. Archives of neurology, 1993, Volume: 50, Issue:8 Topics: Adolescent; Adult; Amitriptyline; Blood Pressure; Chromatography, High Pressure Liquid; Discriminant Analysis; Female; Humans; Male; Middle Aged; Migraine Disorders; Pain Measurement; Propranolol; Pulse; Saliva	1993
The Canadian multicenter trial of pallidal deep brain stimulation for cervical dystonia: preliminary results in three patients. Neurosurgical focus, 2004, Jul-15, Volume: 17, Issue:1 Topics: Amitriptyline; Botulinum Toxins; Cannabis; Combined Modality Therapy; Drug Therapy, Combination; Dysarthria; Electric Stimulation Therapy; Electrodes, Implanted; Feasibility Studies; Female; Globus Pallidus; Humans; Lactones; Lorazepam; Magnetic Resonance Imaging; Male; Middle Aged; Propranolol; Rhizotomy; Sulfones; Torticollis; Treatment Outcome	2004
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up. The journal of headache and pain, 2005, Volume: 6, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Atenolol; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Pizotyline; Propranolol; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil; Weight Gain	2005
Cyclic vomiting syndrome in children: experience with 181 cases from southern Iran. World journal of gastroenterology, 2007, Mar-28, Volume: 13, Issue:12 Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Iran; Male; Periodicity; Prognosis; Propranolol; Prospective Studies; Syndrome; Treatment Outcome; Vomiting	2007
Efficacy of amitriptyline, pizotifen and propranolol in the prevention of migraine. Mymensingh medical journal : MMJ, 2013, Volume: 22, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Antiemetics; Child; Domperidone; Female; Humans; Male; Middle Aged; Migraine Disorders; Pizotyline; Propranolol; Severity of Illness Index; Time Factors; Treatment Outcome; Vasodilator Agents; Young Adult	2013

Other Studies

97 other study(ies) available for amitriptyline and propranolol

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Computation of brain-blood partitioning of organic solutes via free energy calculations. Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24 Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives. European journal of medicinal chemistry, 2021, Nov-05, Volume: 223 Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones	2021
[Cyclic AMP and plasma renin activity in renal vein blood after amitryptiline, theophylline, furosemide and beta adrenergic blocking substances (author's transl)]. Klinische Wochenschrift, 1976, Nov-15, Volume: 54, Issue:22 Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Cyclic AMP; Furosemide; Humans; Middle Aged; Practolol; Propranolol; Renal Veins; Renin; Theophylline	1976
Bovine fibrinogen-induced 14C-serotonin and other compounds release from human blood platelets. Folia haematologica (Leipzig, Germany : 1928), 1975, Volume: 102, Issue:6 Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Amitriptyline; Animals; Blood Platelets; Cattle; Collagen; Fibrinogen; Humans; Phentolamine; Phosphoenolpyruvate; Platelet Aggregation; Platelet Factor 3; Propranolol; Serotonin	1975
Some aspects of the psychopharmacological activity of maprotiline (Ludiomil): effects of single and repeated treatments. The Journal of international medical research, 1978, Volume: 6, Issue:6 Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Anthracenes; Behavior, Animal; Body Temperature; Clomipramine; Depression, Chemical; Escape Reaction; Haplorhini; Head; Imipramine; Maprotiline; Mice; Muscle Contraction; Phenobarbital; Propranolol; Rats; Reserpine; Shrews	1978
The effects of amitriptyline, mianserin, phenoxybenzamine and propranolol on the release of noradrealine in the rat brain in vivo. Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15 Topics: Amitriptyline; Animals; Brain; Dibenzazepines; Male; Mianserin; Norepinephrine; Normetanephrine; Phenoxybenzamine; Propranolol; Rats; Time Factors	1979
Asymptomatic idiopathic syndrome of prolonged Q-T interval in a 45-year-old woman. Ventricular tachyarrhythmias precipitated by hypokalemia and therapy with amitriptyline and prephenazine. Chest, 1977, Volume: 71, Issue:2 Topics: Amitriptyline; Bretylium Tosylate; Electrocardiography; Female; Heart Ventricles; Humans; Hypokalemia; Middle Aged; Perphenazine; Phenytoin; Propranolol; Syncope; Syndrome; Tachycardia	1977
Influence of some antidepressant drugs on the circulatory system: II. Action of amitriptyline and nortriptyline on basic circulatory parameters. Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:6 Topics: Amitriptyline; Animals; Atropine; Cats; Dihydroergotamine; Hemodynamics; In Vitro Techniques; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Nortriptyline; Propranolol; Quaternary Ammonium Compounds; Rabbits; Respiration	1975
Cardiac effects of amitriptyline in rats. Scandinavian journal of clinical and laboratory investigation, 1976, Volume: 36, Issue:1 Topics: Action Potentials; Amitriptyline; Animals; Blood Pressure; Female; Heart; Heart Conduction System; Heart Rate; Myocardium; Propranolol; Rats; Water-Electrolyte Balance	1976
Effect of chlorpromazine on the smg GDS action. Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3 Topics: Amitriptyline; Baclofen; Blood Platelets; Cell Membrane; Chlorpromazine; Dibucaine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; Phenobarbital; Phosphatidic Acids; Phospholipids; Propranolol; rap GTP-Binding Proteins	1992
Post-traumatic migraine: chronic migraine precipitated by minor head or neck trauma. Headache, 1991, Volume: 31, Issue:7 Topics: Adolescent; Adult; Amitriptyline; Chronic Disease; Craniocerebral Trauma; Female; Humans; Male; Middle Aged; Migraine Disorders; Propranolol; Whiplash Injuries	1991
The n-of-1 randomized controlled trial: clinical usefulness. Our three-year experience. Annals of internal medicine, 1990, Feb-15, Volume: 112, Issue:4 Topics: Adult; Amitriptyline; Double-Blind Method; Female; Humans; Patient Compliance; Physician's Role; Propranolol; Randomized Controlled Trials as Topic; Research Design; Syncope	1990
On the inhibition of the mitochondrial inner membrane anion uniporter by cationic amphiphiles and other drugs. The Journal of biological chemistry, 1989, Jan-25, Volume: 264, Issue:3 Topics: Algorithms; Amiodarone; Amitriptyline; Animals; Anion Transport Proteins; Benzodiazepinones; Calcimycin; Carrier Proteins; Hydrogen-Ion Concentration; Imipramine; Intracellular Membranes; Mitochondria; Propranolol; Quinine	1989
[Antimigrainous agents used in maintenance treatment]. La Revue du praticien, 1986, Jan-21, Volume: 36, Issue:5 Topics: Adrenergic beta-Antagonists; Amitriptyline; Aspirin; Benzoxepins; Calcium Channel Blockers; Cinnarizine; Clonidine; Dihydroergotamine; Flunarizine; Humans; Methysergide; Migraine Disorders; Pizotyline; Propranolol	1986
Experimental amitriptyline intoxication: treatment of cardiac toxicity with sodium bicarbonate. Annals of emergency medicine, 1986, Volume: 15, Issue:9 Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Bicarbonates; Dogs; Electrocardiography; Heart Conduction System; Propranolol; Sodium; Sodium Bicarbonate; Tachycardia	1986
Down-regulation of serotonin2, but not of beta-adrenergic receptors during chronic treatment with amitriptyline is independent of stimulation of serotonin2 and beta-adrenergic receptors. Neuropharmacology, 1986, Volume: 25, Issue:12 Topics: Amitriptyline; Animals; Cerebral Cortex; Dihydroalprenolol; Hippocampus; In Vitro Techniques; Male; Piperazines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Reserpine; Serotonin; Spiperone; Triazoles	1986
Chlorpromazine, other amphiphilic cationic drugs and praziquantel: effects on carbohydrate metabolism of Schistosoma mansoni. Parasitology research, 1987, Volume: 73, Issue:3 Topics: Amitriptyline; Animals; Carbohydrate Metabolism; Chlorpromazine; Fluoxetine; Glucose; Imipramine; Lactates; Praziquantel; Propranolol; Schistosoma mansoni	1987
Diagnosis and therapy of headache. Clinical therapeutics, 1986, Volume: 8, Issue:2 Topics: Adult; Affective Symptoms; Amitriptyline; Analgesics; Drug Therapy, Combination; Female; Headache; Humans; Hypnotics and Sedatives; Propranolol; Psychological Tests	1986
Combination headache: practical experience with a combination of a beta-blocker and an antidepressive. Cephalalgia : an international journal of headache, 1986, Volume: 6 Suppl 5 Topics: Adult; Amitriptyline; Cluster Headache; Drug Therapy, Combination; Female; Headache; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Propranolol	1986
Management of the migraine patient. American family physician, 1986, Volume: 33, Issue:1 Topics: Amitriptyline; Analgesics; Diagnosis, Differential; Diet; Ergotamine; Humans; Hypnotics and Sedatives; Methysergide; Metoclopramide; Migraine Disorders; Oxygen; Propranolol; Stress, Physiological; Verapamil	1986
Changes of transition temperatures of phosphatidylcholine and phosphatidylglycerol in presence of amphiphilic drugs. Chemistry and physics of lipids, 1986, Volume: 39, Issue:1-2 Topics: Amitriptyline; Chlorpromazine; Imipramine; Models, Biological; Phosphatidylcholines; Phosphatidylglycerols; Propranolol; Structure-Activity Relationship; Thermodynamics	1986
Stimulated formation of adenosine 3',5'-monophosphate by desipramine in brain slices. Biochimica et biophysica acta, 1971, Volume: 252, Issue:1 Topics: Adenine; Adenosine Triphosphate; Amitriptyline; Animals; Brain; Carbon Isotopes; Chlorpromazine; Cyclic AMP; Desipramine; Guinea Pigs; Histamine; Imipramine; Male; Norepinephrine; Perphenazine; Phentolamine; Phosphoric Monoester Hydrolases; Propranolol; Rats; Rats, Inbred Strains; Theophylline; Tritium; Veratrine	1971
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine. Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine	1967
Cardiovascular effects of poisoning with tricyclic antidepressants. Acta medica Scandinavica, 1974, Volume: 195, Issue:6 Topics: Adult; Amitriptyline; Blood; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Coma; Depression, Chemical; Electrocardiography; Female; Heart Rate; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Nortriptyline; Oxygen; Oxygen Consumption; Partial Pressure; Positive-Pressure Respiration; Propranolol; Stimulation, Chemical; Suicide; Time Factors	1974
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin. Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53 Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents	1972
Propranolol in the treatment of cardiac arrhythmias associated with amitriptyline intoxication. The Journal of pediatrics, 1973, Volume: 82, Issue:1 Topics: Amitriptyline; Arrhythmias, Cardiac; Atropine; Child, Preschool; Electrocardiography; Female; Humans; Injections, Intravenous; Perphenazine; Propranolol	1973
Migraine. Diagnostic and therapeutic aspects. Postgraduate medicine, 1974, Volume: 56, Issue:3 Topics: Amitriptyline; Analgesics; Cerebrovascular Circulation; Ergotamine; Humans; Methysergide; Migraine Disorders; Neurologic Manifestations; Propranolol; Serotonin; Tranquilizing Agents; Vascular Headaches; Vasomotor System	1974
Pharmacological antagonism of the toxic manifestations of amitriptyline and protriptyline in dogs. Toxicology and applied pharmacology, 1972, Volume: 21, Issue:3 Topics: Amitriptyline; Animals; Antidepressive Agents; Dibenzocycloheptenes; Dogs; Drug Antagonism; Electrocardiography; Heart Rate; Mecamylamine; Methylamines; Physostigmine; Propranolol; Propylamines; Pyridostigmine Bromide	1972
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs. Biochemical pharmacology, 1971, Volume: 20, Issue:7 Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine	1971
Uptake, metabolism and release of (3H)-adrenaline by human platelets. British journal of pharmacology, 1970, Volume: 39, Issue:4 Topics: Albinism; Amitriptyline; Blood Platelets; Chlorpromazine; Epinephrine; Ergotamine; Humans; In Vitro Techniques; Metabolism; Phentolamine; Propranolol; Pyrogallol; Quinolines; Reserpine; Thrombin; Tritium	1970
[Psychovegetative syndrome and its treatment]. Wiener medizinische Wochenschrift (1946), 1971, Mar-06, Volume: 121, Issue:10 Topics: Aged; Amitriptyline; Behavior Therapy; Cardiovascular Diseases; Chlordiazepoxide; Diazepam; Exercise Therapy; Humans; Hydrotherapy; Meprobamate; Propranolol; Psychophysiologic Disorders; Sympatholytics; Terminology as Topic; Tranquilizing Agents	1971
The effect of various drug pretreatments on amine-induced phosphorylase activation and amine uptake. The Journal of pharmacology and experimental therapeutics, 1968, Volume: 162, Issue:1 Topics: Amitriptyline; Animals; Carbon Isotopes; Depression, Chemical; Desipramine; Diphenhydramine; Drug Synergism; Female; Glucosyltransferases; Heart; Imipramine; Isoproterenol; Methylphenidate; Myocardium; Norepinephrine; Promethazine; Propranolol; Rats; Stimulation, Chemical; Tranylcypromine; Triprolidine; Tritium; Tyramine	1968
[Amitriptyline poisoning with severe cardiac arrhythmia. Cardiac arrhythmia treated with propranolol]. Ugeskrift for laeger, 1969, Jan-16, Volume: 131, Issue:3 Topics: Amitriptyline; Arrhythmias, Cardiac; Child, Preschool; Electrocardiography; Humans; Injections, Intravenous; Male; Propranolol; Time Factors	1969
Some observations on the adrenergic blocking activity of desipramine and amitriptyline on aortic strips of rabbits. Experientia, 1969, Feb-15, Volume: 25, Issue:2 Topics: Amitriptyline; Animals; Aorta; Calcium; Chlorpromazine; Desipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rabbits; Receptors, Drug	1969
Effect of certain drugs upon amitriptyline induced electrocardiographic changes. Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:2 Topics: Acetylcholine; Amitriptyline; Animals; Atropine; Blood Pressure; Bradycardia; Bundle-Branch Block; Electrocardiography; Epinephrine; Ergotamine; Female; Heart; Heart Rate; Lanatosides; Male; Neostigmine; Norepinephrine; Phentolamine; Plants, Medicinal; Procainamide; Propranolol; Pyridostigmine Bromide; Quinidine; Rabbits; Rauwolfia; Reserpine; Tachycardia	1966
Effect of amitriptyline antidotes on repetitive extrasystole threshold. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5 Topics: Amitriptyline; Animals; Antidotes; Bicarbonates; Cardiac Complexes, Premature; Dogs; Female; Ganglia, Sympathetic; Male; Physostigmine; Propranolol	1980
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase. Biochemical and biophysical research communications, 1983, Dec-16, Volume: 117, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; ADP Ribose Transferases; Amitriptyline; Animals; Bacterial Toxins; Cadaverine; Calmodulin; Cattle; Cell Line; Cricetinae; Cyclic Nucleotide Phosphodiesterases, Type 1; Diamines; Exotoxins; Kidney; Propranolol; Pseudomonas aeruginosa Exotoxin A; Trifluoperazine; Virulence Factors	1983
The effects of propranolol and amitriptyline on vascular and EMG biofeedback training. Headache, 1984, Volume: 24, Issue:2 Topics: Adolescent; Adult; Aged; Amitriptyline; Biofeedback, Psychology; Female; Humans; Male; Middle Aged; Muscle Contraction; Pain; Pilot Projects; Propranolol; Vasoconstriction	1984
Migraine prophylaxis: prognostic significance of clinical factors. Headache, 1983, Volume: 23, Issue:1 Topics: Adolescent; Adult; Aged; Amitriptyline; Child; Child, Preschool; Female; Humans; Male; Methysergide; Middle Aged; Migraine Disorders; Pizotyline; Prognosis; Propranolol	1983
Clonidine withdrawal complicated by amitriptyline therapy. Anesthesiology, 1983, Volume: 59, Issue:1 Topics: Aged; Amitriptyline; Anxiety; Clonidine; Female; Humans; Hypertension; Intraoperative Care; Methyldopa; Nitroprusside; Postoperative Care; Propranolol; Substance Withdrawal Syndrome; Tachycardia	1983
Behavioural effects of long term inhibition of 5-hydroxytryptamine receptors using metergoline. Journal de physiologie, 1981, Volume: 77, Issue:2-3 Topics: Amitriptyline; Animals; Ergolines; Fluoxetine; Male; Metergoline; Motor Activity; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin	1981
Asystole complicating physostigmine treatment of tricyclic antidepressant overdose. Annals of emergency medicine, 1980, Volume: 9, Issue:11 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Heart Arrest; Humans; Imipramine; Male; Parasympatholytics; Physostigmine; Propranolol	1980
Withdrawal from chronic treatment with metergoline, dl-propranolol and amitriptyline enhances serotonin receptor mediated behaviour in the rat. European journal of pharmacology, 1982, Apr-08, Volume: 79, Issue:1-2 Topics: Amitriptyline; Animals; Behavior, Animal; Clomipramine; Ergolines; Humans; Iprindole; Male; Metergoline; Methoxydimethyltryptamines; Motor Activity; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Substance Withdrawal Syndrome	1982
Interval therapy of migraine: long-term results. Headache, 1980, Volume: 20, Issue:6 Topics: Adolescent; Adult; Aged; Amitriptyline; Cyproheptadine; Ergonovine; Ergotamine; Humans; Middle Aged; Migraine Disorders; Papaverine; Phenelzine; Propranolol; Time Factors	1980
The measurement of antagonist potency and the importance of selective inhibition of agonist uptake processes. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1 Topics: Albuterol; Amitriptyline; Animals; Desipramine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Metanephrine; Methoxamine; Models, Biological; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Drug; Regression Analysis	1981
Comparative electrophysiological effects of the antidepressants fluvoxamine and amitriptyline in the canine heart after myocardial infarction. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Dogs; Electrocardiography; Evoked Potentials; Fluvoxamine; Heart; Myocardial Infarction; Propranolol	1996
Sleep-related painful erections: clinical and polysomnographic features. Journal of sleep research, 1996, Volume: 5, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Humans; Lorazepam; Male; Middle Aged; Narcolepsy; Paroxetine; Penile Erection; Polysomnography; Propranolol; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sexual Dysfunctions, Psychological; Sleep Stages; Sleep, REM	1996
[Primary chronic daily headache: a report on 52 cases]. Arquivos de neuro-psiquiatria, 1998, Volume: 56, Issue:1 Topics: Adolescent; Adult; Aged; Amitriptyline; Chronic Disease; Drug Administration Schedule; Female; Follow-Up Studies; Headache; Humans; Male; Middle Aged; Propranolol; Prospective Studies	1998
On-line capillary electrophoresis-electrospray ionization mass spectrometry using a polymerized anionic surfactant. Electrophoresis, 1998, Volume: 19, Issue:12 Topics: Adrenergic beta-Antagonists; Alprenolol; Amitriptyline; Anions; Antidepressive Agents, Tricyclic; Cations; Doxepin; Electrophoresis, Capillary; Imipramine; Mass Spectrometry; Polymers; Propranolol; Sulfates; Surface-Active Agents; Undecylenic Acids	1998
New "triptans" and other drugs for migraine. The Medical letter on drugs and therapeutics, 1998, Oct-09, Volume: 40, Issue:1037 Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents	1998
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones. Journal of neuroendocrinology, 1999, Volume: 11, Issue:11 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium	1999
Structure-activity relationship of P-glycoprotein substrates and modifiers. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:1 Topics: Adenosine Triphosphatases; Amiodarone; Amitriptyline; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Daunorubicin; Diltiazem; Kinetics; Micelles; Progesterone; Propranolol; Structure-Activity Relationship; Verapamil; Vinblastine	2000
Performance of an ultra-low elution-volume 96-well plate: drug discovery and development applications. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:2 Topics: Amitriptyline; Animals; Calibration; Chemical Precipitation; Chromatography, Liquid; Drug Evaluation, Preclinical; Mice; Microchemistry; Pharmaceutical Preparations; Propranolol; Proteins; Rats; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2003
Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture. Neuroscience, 2003, Volume: 118, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amitriptyline; Animals; Animals, Newborn; Antidepressive Agents; Biogenic Monoamines; Blotting, Western; Carrier Proteins; Culture Techniques; DNA Primers; DNA, Complementary; Drug Interactions; Female; Fluoxetine; Gene Expression Regulation; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phenols; Piperazines; Pregnancy; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Serotonin; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sulfonamides	2003
Bending the rule of monotherapy for migraine prevention? Headache, 2005, Volume: 45, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Drug Therapy, Combination; Female; Humans; Migraine Disorders; Propranolol; Valproic Acid	2005
Pharmacological prevention of migraine: to be considered case by case. Prescrire international, 2006, Volume: 15, Issue:85 Topics: Adrenergic beta-Antagonists; Amitriptyline; Anticonvulsants; Antidepressive Agents; Cost-Benefit Analysis; Flunarizine; France; Humans; Methysergide; Migraine Disorders; Pizotyline; Propranolol; Serotonin Antagonists; United Kingdom; Valproic Acid	2006
Persistence with migraine prophylactic treatment and acute migraine medication utilization in the managed care setting. Clinical therapeutics, 2008, Volume: 30, Issue:12 Topics: Adult; Age Factors; Amitriptyline; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Humans; Kaplan-Meier Estimate; Male; Managed Care Programs; Medication Adherence; Middle Aged; Migraine Disorders; Proportional Hazards Models; Propranolol; Retrospective Studies; Sex Factors; Time Factors; Timolol; Topiramate; Valproic Acid	2008
Short-term outcomes of tension type and migraine headache in children. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2008, Volume: 91 Suppl 3 Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Humans; Male; Migraine Disorders; Propranolol; Prospective Studies; Tension-Type Headache; Thailand; Time Factors; Treatment Outcome; Vasodilator Agents	2008
Does adenosine A(1) receptor stimulation causes QRS prolongation by blocking beta adrenergic receptors in amitriptyline poisoning? Toxicology letters, 2009, Apr-25, Volume: 186, Issue:2 Topics: Adenosine A1 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Xanthines	2009
Prophylactic drugs and cytokine and leptin levels in children with migraine. Pediatric neurology, 2009, Volume: 41, Issue:4 Topics: Adolescent; Amitriptyline; Central Nervous System Agents; Child; Cyproheptadine; Cytokines; Female; Flunarizine; Humans; Interleukin-1beta; Interleukin-6; Leptin; Male; Migraine Disorders; Propranolol; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha	2009
Cyclic vomiting syndrome in Taiwanese children. Journal of the Formosan Medical Association = Taiwan yi zhi, 2011, Volume: 110, Issue:1 Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Age of Onset; Amitriptyline; Asian People; Child; Child, Preschool; Cyproheptadine; Female; Follow-Up Studies; Humans; Male; Migraine Disorders; Nausea; Propranolol; Retrospective Studies; Taiwan; Treatment Outcome; Vomiting	2011
[Preventive migraine drugs--they are indeed still working]. Ugeskrift for laeger, 2011, Mar-14, Volume: 173, Issue:11 Topics: Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Humans; Migraine Disorders; Propranolol; Treatment Outcome	2011
Nonpharmacologic treatment of migraine with low-dose propranolol or amitriptyline. Pediatric neurology, 2012, Volume: 46, Issue:6 Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Databases, Factual; Female; Follow-Up Studies; Humans; Male; Medical Records; Migraine Disorders; Propranolol; Treatment Outcome	2012
Primary pseudotumor cerebri syndrome in a young obese African woman. The Israel Medical Association journal : IMAJ, 2014, Volume: 16, Issue:9 Topics: Acetazolamide; Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Antihypertensive Agents; Diuretics; Female; Glucocorticoids; Humans; Obesity; Ophthalmoscopy; Papilledema; Prednisolone; Propranolol; Pseudotumor Cerebri; Treatment Outcome; Visual Acuity	2014
Short- and long-term outcomes of children with cyclic vomiting syndrome. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97, Issue:10 Topics: Adolescent; Adrenergic beta-Antagonists; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Male; Propranolol; Retrospective Studies; Treatment Outcome; Vomiting	2014
Cost-effectiveness analysis of interventions for migraine in four low- and middle-income countries. The journal of headache and pain, 2015, Feb-18, Volume: 16 Topics: Amitriptyline; China; Cost-Benefit Analysis; Fructose; Humans; Income; India; Medication Adherence; Migraine Disorders; Models, Economic; Propranolol; Russia; Self Care; Topiramate; Treatment Outcome; Zambia	2015
Association of MDR1, CYP2D6, and CYP2C19 gene polymorphisms with prophylactic migraine treatment response. Journal of the neurological sciences, 2016, Jul-15, Volume: 366 Topics: Adult; Amitriptyline; ATP Binding Cassette Transporter, Subfamily B; Central Nervous System Agents; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Drug Resistance; Female; Fructose; Gene Frequency; Genetic Association Studies; Humans; Male; Migraine Disorders; Polymorphism, Genetic; Propranolol; Risk Factors; Topiramate; Treatment Outcome; Valproic Acid	2016
Factors Influencing Response to Pharmacologic Treatment of Migraine in a Pediatric Headache Clinic. Headache, 2016, Volume: 56, Issue:7 Topics: Adolescent; Age Factors; Amitriptyline; Central Nervous System Agents; Child; Child, Preschool; Cohort Studies; Comorbidity; Female; Follow-Up Studies; Fructose; Humans; Male; Mental Disorders; Migraine Disorders; Propranolol; Puberty; Tertiary Care Centers; Topiramate; Treatment Outcome	2016
Dramatic resuscitation with Intralipid in an epinephrine unresponsive cardiac arrest following overdose of amitriptyline and propranolol. BMJ case reports, 2017, Mar-02, Volume: 2017 Topics: Adult; Amitriptyline; Drug Overdose; Epinephrine; Fat Emulsions, Intravenous; Female; Heart Arrest; Humans; Propranolol; Resuscitation; Treatment Outcome	2017
Repurposing of Existing Drugs for the Bacterial Infections: An In silico and In vitro Study. Infectious disorders drug targets, 2020, Volume: 20, Issue:2 Topics: Amitriptyline; Anti-Bacterial Agents; Computer Simulation; Drug Repositioning; Gram-Negative Bacteria; Gram-Positive Bacteria; Metformin; Microbial Sensitivity Tests; Propranolol	2020
Analysis of the effectiveness of the prophylaxis of vestibular migraine depending on the diagnostic category and the prescribed drug. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020, Volume: 277, Issue:4 Topics: Acetazolamide; Amitriptyline; Analgesics; Central Nervous System Agents; Flunarizine; Humans; Migraine Disorders; Propranolol; Prospective Studies; Topiramate; Vertigo; Vestibular Diseases	2020
β-Cyclodextrin Polymerized in Cross-Flowing Channels of Biomass Sawdust for Rapid and Highly Efficient Pharmaceutical Pollutants Removal from Water. ACS applied materials & interfaces, 2020, Jul-22, Volume: 12, Issue:29 Topics: Amitriptyline; Biomass; Cellulose; Chlortetracycline; Cyclodextrins; Diclofenac; Drug Contamination; Levofloxacin; Particle Size; Propranolol; Surface Properties; Water Pollutants, Chemical; Wood	2020
Postinjury treatments to make early tactical aeromedical evacuation practical for the brain after TBI. The journal of trauma and acute care surgery, 2021, 08-01, Volume: 91, Issue:2S Suppl 2 Topics: Adenosine; Air Ambulances; Allopurinol; Amitriptyline; Animals; Brain; Brain Chemistry; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Emergency Medical Services; Lidocaine; Magnesium; Male; Mice; Mice, Inbred C57BL; Propranolol; Rotarod Performance Test	2021