amitriptyline and phenylephrine

amitriptyline has been researched along with phenylephrine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's2 (10.53)18.2507
2000's2 (10.53)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Coppen, A; Ghose, K1
Coppen, A; Wood, K1
Mason, BD; Van Petten, GR1
Banjar, W; Bradshaw, CM; Longmore, J; Szabadi, E1
Bradshaw, CM; Longmore, J; Szabadi, E1
Weinstock, M1
Heisel, J; Lamarche, M; Royer, R1
Witton, K1
Ghose, K1
Aghajanian, GK; Gallager, DW; Menkes, DB1
Aghajanian, GK; Davis, M; Gallager, DW; Kehne, JH; Menkes, DB1
Coppen, A; Wood, KM1
Fawcett, JP; Menkes, DB; Patel, PP1
Asbun, J; Castillo, C; Castillo, EF; Ocharan, ME; Valencia, I1
Cheevers, CV; Donello, JE; Gil, DW1
Bleich, S; Frieling, H; Herbst, D; Nedeljkov, V; Nedeljkov-Jancic, R; Pavlovic, D; Ribback, S; Wendt, M1
Gmiro, VE; Serdiuk, SE1

Trials

2 trial(s) available for amitriptyline and phenylephrine

ArticleYear
Comparison of the effects of binodaline and amitriptyline on peripheral autonomic functions in healthy volunteers.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents; Autonomic Nervous System; Carbachol; Double-Blind Method; Humans; Indoles; Male; Phenylephrine; Pupil; Salivation; Sweating

1985
Assessment of Peripheral adrenergic activity and its interactions with drugs in man.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:4

    Topics: Adrenergic Agonists; Adult; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Drug Interactions; Electroconvulsive Therapy; Female; Haloperidol; Humans; Lithium; Male; Middle Aged; Norepinephrine; Phenylephrine; Receptors, Adrenergic; Sympathomimetics; Tyramine

1980

Other Studies

17 other study(ies) available for amitriptyline and phenylephrine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Peripheral alpha-adrenoreceptor and central dopamine receptor activity in depressive patients.
    Psychopharmacology, 1978, Oct-31, Volume: 59, Issue:2

    Topics: Adult; Amitriptyline; Blood Pressure; Bromocriptine; Depression; Female; Humans; Male; Norepinephrine; Phenylephrine; Prolactin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Dopamine; Tyramine

1978
Adrenergic and serotonergic mechanisms in depression and their response to amitriptyline.
    Ciba Foundation symposium, 1979, Issue:74

    Topics: Amitriptyline; Blood Platelets; Blood Pressure; Depression; Female; Humans; Male; Norepinephrine; Phenylephrine; Serotonin; Sympathetic Nervous System; Tyramine

1979
Effects of tricyclic antidepressants on cardiovascular responses to norepinephrine and phenylephrine during pregnancy.
    American journal of obstetrics and gynecology, 1978, Aug-15, Volume: 131, Issue:8

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Female; Imipramine; Norepinephrine; Phenylephrine; Placenta; Pregnancy; Pregnancy, Animal; Regional Blood Flow; Sheep; Uterus

1978
Antagonism of phenylephrine-evoked sweating by trazodone and amitriptyline in humans in vivo.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Amitriptyline; Delayed-Action Preparations; Humans; Male; Phenylephrine; Sweating; Trazodone

1987
The role of the sympathetic nervous system in mediating the action of analgesic drugs on the lens.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Amitriptyline; Amphetamine; Animals; Bretylium Compounds; Cocaine; Dopamine; Ephedrine; Epinephrine; Guanethidine; Imipramine; Iproniazid; Lens, Crystalline; Metaraminol; Methadone; Mice; Nialamide; Norepinephrine; Phenylephrine; Reserpine; Sympathetic Nervous System; Synephrine

1968
[Experimental study of direct vascular activity of amitriptyline].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1967, Volume: 161, Issue:11

    Topics: Amitriptyline; Animals; Blood Vessels; Central Nervous System Stimulants; Ethanolamines; Heart; Hypertension; Isoproterenol; Norepinephrine; Phenylephrine; Rabbits

1967
Circulatory lability and depression.
    Journal of the American Geriatrics Society, 1966, Volume: 14, Issue:10

    Topics: Aged; Amitriptyline; Blood Pressure Determination; Depression; Dysautonomia, Familial; Humans; Hypertension; Hypotension, Orthostatic; Male; Methandrostenolone; Phenothiazines; Phenylephrine

1966
Chronic antidepressant treatment enhances agonist affinity of brain alpha 1-adrenoceptors.
    European journal of pharmacology, 1983, Jan-28, Volume: 87, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Brain; Desipramine; Iprindole; Kinetics; Male; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thalamus

1983
Functional supersensitivity of CNS alpha 1-adrenoceptors following chronic antidepressant treatment.
    Life sciences, 1983, Jul-11, Volume: 33, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Binding Sites; Desipramine; Hydroxydopamines; Iprindole; Male; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex, Acoustic

1983
Peripheral serotonergic and adrenergic responses in depression.
    Acta psychiatrica Scandinavica. Supplementum, 1980, Volume: 280

    Topics: Affective Symptoms; Amitriptyline; Blood Platelets; Blood Pressure; Depression; Female; Humans; Male; Norepinephrine; Nortriptyline; Phenylephrine; Psychiatric Status Rating Scales; Receptors, Adrenergic; Serotonin; Tyramine

1980
Antidepressant treatment and chemical sympathectomy fail to modulate alpha 1-adrenoceptor sensitivity in mouse eye.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Administration, Topical; Amitriptyline; Animals; Antidepressive Agents; Benzamides; Desipramine; Down-Regulation; Fluoxetine; Injections, Intraperitoneal; Male; Methoxamine; Mice; Moclobemide; Oxidopamine; Phentolamine; Phenylephrine; Prazosin; Pupil; Receptors, Adrenergic, alpha-1; Sympathectomy, Chemical; Time Factors

1993
A study of the interactions of tricyclic antidepressants with alpha 1-adrenoceptor subtypes in rat aorta and caudal arteries.
    Proceedings of the Western Pharmacology Society, 1998, Volume: 41

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Arteries; Clomipramine; Dose-Response Relationship, Drug; Drug Interactions; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1

1998
Transient allodynia pain models in mice for early assessment of analgesic activity.
    British journal of pharmacology, 2008, Volume: 153, Issue:4

    Topics: Adrenergic alpha-Antagonists; Amines; Amitriptyline; Analgesics; Animals; Clonidine; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; N-Methylaspartate; Pain; Peripheral Nervous System; Phenylephrine; Piperazines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reproducibility of Results; Spinal Cord; Spinal Nerves; Time Factors

2008
Effects of amitriptyline, fluoxetine, tranylcypromine and venlafaxine on rat vascular smooth muscle in vitro--the role of the endothelium.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Aorta, Abdominal; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Cyclohexanols; Dinoprost; Endothelium, Vascular; Fluoxetine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Phenylephrine; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Inbred Lew; Selective Serotonin Reuptake Inhibitors; Tranylcypromine; Venlafaxine Hydrochloride

2012
[Phenylephrine potentiates antidepressive and eliminates sedative action of amitriptyline in rats].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2014, Volume: 100, Issue:1

    Topics: Afferent Pathways; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Drug Interactions; Gastric Mucosa; Injections, Intramuscular; Male; Motor Activity; Phenylephrine; Rats; Rats, Wistar; Sympathomimetics; Wakefulness

2014