amitriptyline and phentolamine

amitriptyline has been researched along with phentolamine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's3 (13.04)18.2507
2000's2 (8.70)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Andrews, PR; Craik, DJ; Martin, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Holan, J; Kubisz, P; Stránska, M; Suranová, J1
Hughes, IE1
Kodama, T; Matsukado, Y; Shimizu, H; Suzuki, T; Tanaka, S1
Garattini, S; Jori, A; Paglialunga, S1
König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P1
Mason, RG; Read, MS; Saba, SR; Shermer, RW1
Born, GV; Smith, JB1
Jones, BJ; Roberts, DJ; Tolman, BD1
Barnett, A; Greenhouse, DD; Taber, RI1
Nymark, M; Rasmussen, J1
Desager, JP; Harvengt, C; Leonard, JP; Van der Linden, L1
Doggrell, SA; Vincent, L1
Beek, D; Kenakin, TP1
Eisenach, JC; Gebhart, GF1
Fawcett, JP; Menkes, DB; Patel, PP1
Fujiseki, Y; Inagaki, C; Kinoshita, T; Okugawa, G; Omori, K; Suzukawa, J1
KLINE, NS1
Reid, AR; Sawynok, J; Waldron, JB1

Reviews

1 review(s) available for amitriptyline and phentolamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for amitriptyline and phentolamine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Bovine fibrinogen-induced 14C-serotonin and other compounds release from human blood platelets.
    Folia haematologica (Leipzig, Germany : 1928), 1975, Volume: 102, Issue:6

    Topics: Acid Phosphatase; Adenosine; Adenosine Diphosphate; Amitriptyline; Animals; Blood Platelets; Cattle; Collagen; Fibrinogen; Humans; Phentolamine; Phosphoenolpyruvate; Platelet Aggregation; Platelet Factor 3; Propranolol; Serotonin

1975
The effect of amitriptyline on presynaptic mechanisms in noradrenergic nerves.
    British journal of pharmacology, 1978, Volume: 63, Issue:2

    Topics: Amitriptyline; Animals; Atropine; Cocaine; Electric Stimulation; In Vitro Techniques; Male; Mice; Nervous System; Norepinephrine; Phentolamine; Vas Deferens

1978
Stimulated formation of adenosine 3',5'-monophosphate by desipramine in brain slices.
    Biochimica et biophysica acta, 1971, Volume: 252, Issue:1

    Topics: Adenine; Adenosine Triphosphate; Amitriptyline; Animals; Brain; Carbon Isotopes; Chlorpromazine; Cyclic AMP; Desipramine; Guinea Pigs; Histamine; Imipramine; Male; Norepinephrine; Perphenazine; Phentolamine; Phosphoric Monoester Hydrolases; Propranolol; Rats; Rats, Inbred Strains; Theophylline; Tritium; Veratrine

1971
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine

1967
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents

1972
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
    Thrombosis et diathesis haemorrhagica, 1972, Feb-29, Volume: 27, Issue:1

    Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds

1972
Uptake, metabolism and release of (3H)-adrenaline by human platelets.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Albinism; Amitriptyline; Blood Platelets; Chlorpromazine; Epinephrine; Ergotamine; Humans; In Vitro Techniques; Metabolism; Phentolamine; Propranolol; Pyrogallol; Quinolines; Reserpine; Thrombin; Tritium

1970
Studies on interactions involving antidepressive and other drugs with tetrabenazine and noradnamine on locomotor activity in mice, including details of the experimental design and statistical analysis.
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Amitriptyline; Analysis of Variance; Animals; Atropine; Bretylium Compounds; Chlorpromazine; Cycloheptanes; Depression, Chemical; Dextroamphetamine; Dibenzocycloheptenes; Drug Antagonism; Ketones; Male; Mice; Motor Activity; Nialamide; Nortriptyline; Phentolamine; Tetrabenazine

1970
A new type of drug enhancement: increased maximum response to cumulative noradrenaline in the isolated rat vas deferens.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:1

    Topics: Amitriptyline; Animals; Cocaine; Desipramine; Drug Synergism; Imipramine; Male; Muscle Contraction; Norepinephrine; Phentolamine; Rats; Vas Deferens

1968
Effect of certain drugs upon amitriptyline induced electrocardiographic changes.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:2

    Topics: Acetylcholine; Amitriptyline; Animals; Atropine; Blood Pressure; Bradycardia; Bundle-Branch Block; Electrocardiography; Epinephrine; Ergotamine; Female; Heart; Heart Rate; Lanatosides; Male; Neostigmine; Norepinephrine; Phentolamine; Plants, Medicinal; Procainamide; Propranolol; Pyridostigmine Bromide; Quinidine; Rabbits; Rauwolfia; Reserpine; Tachycardia

1966
Amitriptyline binding to specific alpha-adrenergic receptors in vitro.
    Life sciences, 1980, Nov-17, Volume: 27, Issue:20

    Topics: Amitriptyline; Animals; Binding, Competitive; Dihydroergotoxine; Epinephrine; Etilefrine; Female; Kinetics; Phenoxybenzamine; Phentolamine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Uterus

1980
The postsynaptic effects of antidepressant drugs in the rat anococcygeus muscle.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:11

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Atropine; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Synapses

1981
The measurement of antagonist potency and the importance of selective inhibition of agonist uptake processes.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Albuterol; Amitriptyline; Animals; Desipramine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Metanephrine; Methoxamine; Models, Biological; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Drug; Regression Analysis

1981
Intrathecal amitriptyline acts as an N-methyl-D-aspartate receptor antagonist in the presence of inflammatory hyperalgesia in rats.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics, Opioid; Animals; Behavior, Animal; Carrageenan; Drug Interactions; Drug Therapy, Combination; Excipients; Hyperalgesia; Injections, Intravenous; Injections, Spinal; Male; Methysergide; Morphine; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists

1995
Antidepressant treatment and chemical sympathectomy fail to modulate alpha 1-adrenoceptor sensitivity in mouse eye.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Administration, Topical; Amitriptyline; Animals; Antidepressive Agents; Benzamides; Desipramine; Down-Regulation; Fluoxetine; Injections, Intraperitoneal; Male; Methoxamine; Mice; Moclobemide; Oxidopamine; Phentolamine; Phenylephrine; Prazosin; Pupil; Receptors, Adrenergic, alpha-1; Sympathectomy, Chemical; Time Factors

1993
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.
    Journal of neuroendocrinology, 1999, Volume: 11, Issue:11

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium

1999
THE PRACTICAL MANAGEMENT OF DEPRESSION.
    JAMA, 1964, Nov-23, Volume: 190

    Topics: Amitriptyline; Antidepressive Agents; Benzoates; Classification; Depression; Depressive Disorder; Drug Therapy; Electroconvulsive Therapy; Imipramine; Isocarboxazid; Isoniazid; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Phentolamine; Psychopharmacology; Psychotherapy; Reserpine; Sulfates; Toxicology; Tranylcypromine; Vitamin B 12

1964
Amitriptyline produces multiple influences on the peripheral enhancement of nociception by P2X receptors.
    European journal of pharmacology, 2004, Sep-24, Volume: 499, Issue:3

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amitriptyline; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Hyperalgesia; Male; Methysergide; Pain; Phentolamine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Serotonin Antagonists

2004