Compounds > amitriptyline

amitriptyline and phenoxybenzamine

amitriptyline has been researched along with phenoxybenzamine in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (71.43)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (7.14)	29.6817
2010's	3 (21.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fludder, JM; Leonard, BE	1
Kaniike, K; Kurogochi, Y	1
Garattini, S; Jori, A; Paglialunga, S	1
Nymark, M	1
Desager, JP; Harvengt, C; Leonard, JP; Van der Linden, L	1
Crews, FT; Scott, JA; Shorstein, NH	1
Hartman, BK; Hughes, CW; Irwin, GH; Preskorn, SH	1
Barnes, CD; Fung, SJ; Gintautas, J	1
HOLLISTER, LE; KIMBELL, I; MEYER, F; OVERALL, JE; SHELTON, J	1

Reviews

1 review(s) available for amitriptyline and phenoxybenzamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

13 other study(ies) available for amitriptyline and phenoxybenzamine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
The effects of amitriptyline, mianserin, phenoxybenzamine and propranolol on the release of noradrealine in the rat brain in vivo. Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15 Topics: Amitriptyline; Animals; Brain; Dibenzazepines; Male; Mianserin; Norepinephrine; Normetanephrine; Phenoxybenzamine; Propranolol; Rats; Time Factors	1979
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents	1972
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine. Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 165, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine	1967
Apomorphine provoked stereotype in the dog. Psychopharmacologia, 1972, Volume: 26, Issue:4 Topics: Amitriptyline; Animals; Anisoles; Apomorphine; Atropine; Behavior, Animal; Benzamides; Benztropine; Diazepam; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethylamines; Female; Fluphenazine; Haloperidol; Humans; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Piperazines; Receptors, Drug; Scopolamine; Stereotyped Behavior; Xanthenes	1972
Amitriptyline binding to specific alpha-adrenergic receptors in vitro. Life sciences, 1980, Nov-17, Volume: 27, Issue:20 Topics: Amitriptyline; Animals; Binding, Competitive; Dihydroergotoxine; Epinephrine; Etilefrine; Female; Kinetics; Phenoxybenzamine; Phentolamine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Uterus	1980
Rapid down-regulation of serotonin2 receptor binding during combined administration of tricyclic antidepressant drugs and alpha 2 antagonists. Neuropharmacology, 1983, Volume: 22, Issue:10 Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Desipramine; Kinetics; Male; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone	1983
Role of the central adrenergic system in mediating amitriptyline-induced alteration in the mammalian blood-brain barrier in vivo. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:2 Topics: Amitriptyline; Animals; Atropine; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Hydroxydopamines; Hydroxyzine; Male; Neurons; Oxidopamine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Serotonin	1982
Brainstem noradrenergic system depression by cyclobenzaprine. Neuropharmacology, 1980, Volume: 19, Issue:2 Topics: Amitriptyline; Animals; Axons; Brain Stem; Cats; Female; Locus Coeruleus; Male; Norepinephrine; Phenoxybenzamine; Reflex, Monosynaptic; Sympathetic Nervous System	1980
IMIPRAMINE AND THIORIDAZINE IN DEPRESSED AND SCHIZOPHRENIC PATIENTS. ARE THERE SPECIFIC ANTIDEPRESSANT DRUGS? JAMA, 1964, Aug-24, Volume: 189 Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Computers; Depression; Drug Therapy; Imipramine; Pharmacology; Phenothiazines; Phenoxybenzamine; Psychological Tests; Schizophrenia; Thioridazine	1964