amitriptyline and pentobarbital

amitriptyline has been researched along with pentobarbital in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199034 (80.95)18.7374
1990's1 (2.38)18.2507
2000's3 (7.14)29.6817
2010's4 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Sen, S; Sinha, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barnes, CD; Hughes, MJ; Light, KE; Messiha, FS1
Fujimoto, S; Hisada, S1
Huang, CL; Liu, SJ; Waters, IW1
Burov, IuV; Salimov, RM1
Goodwin, GM; Gray, JA; Green, AR; Heal, DJ1
Bennett, GW; Green, AR; Lighton, C; Marsden, CA1
Yamamoto, J1
Greengard, P; Quinn, GP; Reid, MB1
Hartmann, E2
Hauri, P; Hawkins, DR1
Riedmann, M1
Brittain, RT1
Da Prada, M; Pletscher, A1
Lind, N; Parkes, MW1
Bevegård, S; Thorstrand, C1
Bassett, JR; Cairncross, KD1
Kamei, C; Masuda, Y; Shimizu, M1
Kamei, C; Shimomura, K; Ueki, S1
Nurimoto, S; Ogawa, N; Ueki, S2
Dennis, AJ; Hobbs, DR; Hudson, JB; Sussman, HC1
Irwin, S1
Egbers, HJ; Möllmann, H2
Hulting, J; Thorstrand, C1
Foxwell, MH; Funderburk, WH; Hakala, MW1
Ben-Horin, P; Meyers, GM; Traub, AC; Vogel, GW1
Kammerer, T; Tyano, S1
Greer, NL; Schechter, MD1
Eandi, M; Ricci Gamalero, S; Taglia, P2
Imamura, T; Jitsufuchi, N; Kudo, K; Nagata, T; Tokunaga, H; Zhang, XX1
HORACKOVA, E1
Betit, CC; Dean, D; Desrosiers, NA; Watterson, JH; Wyman, JF1

Reviews

3 review(s) available for amitriptyline and pentobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan

1969
Gas chromatographic analysis of drugs and drug metabolites in biological samples.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:7

    Topics: Acylation; Alkylation; Amitriptyline; Chloramphenicol; Chromatography, Gas; Chromatography, Ion Exchange; Drug Stability; Evaluation Studies as Topic; Hydrazones; Hydrogen-Ion Concentration; Methods; Methylation; Microchemistry; Oximes; Pentobarbital; Pharmaceutical Preparations; Silicon Dioxide; Temperature; Testosterone; Thiopental; Time Factors

1973

Trials

1 trial(s) available for amitriptyline and pentobarbital

ArticleYear
The effect of four drugs on sleep patterns in man.
    Psychopharmacologia, 1968, Volume: 12, Issue:4

    Topics: Adult; Amitriptyline; Chlordiazepoxide; Electroencephalography; Electromyography; Humans; Hypnotics and Sedatives; Oculomotor Muscles; Pentobarbital; Placebos; Sleep; Time Factors

1968

Other Studies

38 other study(ies) available for amitriptyline and pentobarbital

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Behavioral effects of cyclobenzaprine.
    Proceedings of the Western Pharmacology Society, 1979, Volume: 22

    Topics: Amitriptyline; Animals; Behavior, Animal; Dextroamphetamine; Female; Humans; Male; Mice; Mice, Inbred Strains; Motor Activity; Muscle Relaxants, Central; Pentobarbital; Rats; Sleep; Stereotyped Behavior

1979
Effects of centrally affecting drugs on the diuretic and antidiuretic actions of intracerebroventricular prostaglandin E2.
    Japanese journal of pharmacology, 1978, Volume: 28, Issue:1

    Topics: Amitriptyline; Animals; Central Nervous System; Diazepam; Diuresis; Drug Interactions; gamma-Aminobutyric Acid; Injections, Intraventricular; Morphine; Norepinephrine; Pentobarbital; Prostaglandins E; Rats; Reserpine; Time Factors

1978
Interactions of tricyclic antidepressants and barbiturates in barbiturate-tolerant and nontolerant rats.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Barbiturates; Brain Chemistry; Desipramine; Drug Interactions; Drug Tolerance; Imipramine; Male; Microsomes, Liver; Nortriptyline; Pentobarbital; Rats; Sleep; Time Factors

1975
[The effect of pharmacologic substances on intraspecies aggression].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:5

    Topics: Aggression; Amitriptyline; Animals; Benactyzine; Chlordiazepoxide; Chlorpromazine; Diazepam; Haloperidol; Humans; Imipramine; Male; Pentobarbital; Psychotropic Drugs; Rats; Trifluoperazine

1975
Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: 5,7-Dihydroxytryptamine; Amitriptyline; Animals; Antidepressive Agents; Baclofen; Body Temperature; Electroshock; Flurazepam; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Neural Pathways; Pentobarbital; Receptors, GABA-A

1987
Changes in the behavioural response to a TRH analogue following chronic amitriptyline treatment and repeated electroconvulsive shock in the rat.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: Amitriptyline; Animals; Arousal; Behavior, Animal; Body Temperature; Catheterization; Electrodes, Implanted; Electroshock; Motor Activity; Nucleus Accumbens; Pentobarbital; Rats; Rats, Inbred Strains; Respiration; Sleep; Thyrotropin-Releasing Hormone

1986
Characteristics of the cortical and hippocampal EEG power spectra of rabbits during normal behavioral states and after administration of CNS acting drugs.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:3

    Topics: Amitriptyline; Animals; Behavior, Animal; Central Nervous System Agents; Cerebral Cortex; Chlorpromazine; Diazepam; Electroencephalography; Hippocampus; Male; Morphine; Motor Cortex; Pentobarbital; Rabbits; Time Factors

1985
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Human sleep after leucotomy. A case study.
    Archives of general psychiatry, 1972, Volume: 26, Issue:5

    Topics: Amitriptyline; Chlorpromazine; Depression; Electroencephalography; Female; Frontal Lobe; Humans; Middle Aged; Pentobarbital; Postoperative Complications; Psychosurgery; Sleep; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Wakefulness

1972
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl

1966
On the mechanism of chlorpromazine-induced changes of cerebral homovanillic acid levels.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Barbiturates; Brain Stem; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Diazepam; Dopamine; Haloperidol; Hydroxyindoleacetic Acid; Imipramine; Meprobamate; Pentobarbital; Phenylacetates; Rats; Reserpine; Spectrophotometry

1966
Effects of inhibition and induction of the liver microsomal enzyme system on the narcotic activity of ethanol in mice.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:1

    Topics: Amitriptyline; Animals; Chlorpromazine; Drug Synergism; Enzyme Induction; Ethanol; Female; Imipramine; Liver; Mice; Microsomes; Pentobarbital; Proadifen; Sleep

1967
Central hemodynamics in severe poisoning by hypnotic drugs. Coma depth and body temperature.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:4

    Topics: Adult; Aged; Amitriptyline; Blood Pressure; Body Temperature; Cardiac Output; Central Venous Pressure; Chlorpromazine; Chlorprothixene; Coma; Dibenzazepines; Female; Glutethimide; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nortriptyline; Oxygen Consumption; Pentobarbital; Phenothiazines; Tranquilizing Agents; Vascular Resistance

1972
Effects of psychoactive drugs on responses of the rat to aversive stimulation.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:2

    Topics: Amitriptyline; Animals; Avoidance Learning; Chlorpromazine; Corticosterone; Diazepam; Electroshock; Light; Male; Pentobarbital; Psychotropic Drugs; Rats; Stress, Physiological; Time Factors

1974
Effects of psychotropic drugs on hypothalamic self-stimulation behavior in rats.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:4

    Topics: Amitriptyline; Animals; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Haloperidol; Hypothalamus; Imipramine; Male; Methamphetamine; Methotrimeprazine; Motor Activity; Motor Skills; Pentobarbital; Psychotropic Drugs; Rats; Self Stimulation; Stimulation, Chemical; Tranquilizing Agents

1974
Significance of withdrawal jumping response in predicting physical dependence in mice.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome

1973
Effects of psychotropic drugs on hyperemotionality of rats with bilateral ablations of the olfactory bulbs and olfactory tubercles.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Diazepam; Emotions; Haloperidol; Imipramine; Male; Meprobamate; Olfactory Bulb; Pentobarbital; Rats; Reserpine; Tranquilizing Agents

1974
Effects of psychotropic drugs on emotional behavior in rats with limbic lesions, with special reference to olfactory bulb ablations.
    Folia psychiatrica et neurologica japonica, 1972, Volume: 26, Issue:3

    Topics: Amitriptyline; Animals; Behavior, Animal; Chloramphenicol; Chlorpromazine; Depression, Chemical; Diazepam; Emotions; Imipramine; Limbic System; Male; Olfactory Bulb; Pentobarbital; Psychopharmacology; Rats

1972
Extended hemodialysis in short acting barbiturate poisoning: case report.
    Southern medical journal, 1969, Volume: 62, Issue:4

    Topics: Adult; Amitriptyline; Barbiturates; Chlorpromazine; Female; Humans; Pentobarbital; Perphenazine; Positive-Pressure Respiration; Renal Dialysis; Secobarbital; Suicide

1969
Interspecies comparison of drug effects in primates.
    Psychopharmacology bulletin, 1969, Volume: 5, Issue:2

    Topics: Amitriptyline; Animals; Behavior, Animal; Dextroamphetamine; Haplorhini; Pentobarbital; Species Specificity

1969
[Comparative study on the influence of psychotropic agents on stress induced lesions of the gastric mucosa].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:4

    Topics: Administration, Oral; Amitriptyline; Animals; Chlordiazepoxide; Female; Fluphenazine; Gastric Mucosa; Humans; Pentobarbital; Rats; Stomach Ulcer; Stress, Psychological

1972
Hemodynamic effects of norepinephrine in severe hypnotic drug poisoning with arterial hypotension.
    Acta medica Scandinavica, 1972, Volume: 192, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Aged; Amitriptyline; Blood Pressure; Carbamazepine; Cardiac Output; Cardiac Volume; Central Venous Pressure; Diazepam; Female; Glutethimide; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Meprobamate; Middle Aged; Norepinephrine; Oxygen; Pentobarbital; Poisoning; Vascular Resistance

1972
A comparative investigation of the effects of specific psychotropic agents on immobilization-induced ulcer.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:3

    Topics: Amitriptyline; Animals; Central Nervous System; Chlordiazepoxide; Drug Synergism; Female; Fluphenazine; Humans; Methods; Pentobarbital; Psychophysiologic Disorders; Rats; Stomach; Stomach Ulcer; Stress, Physiological

1971
Effects of psychotherapeutic drugs on hypothalamic- induced hissing in cats.
    Neuropharmacology, 1970, Volume: 9, Issue:1

    Topics: Amitriptyline; Animals; Cats; Chlordiazepoxide; Chlorpromazine; Desipramine; Electric Stimulation; Female; Hypothalamus; Imipramine; Injections, Intraperitoneal; Male; Pentobarbital; Perphenazine; Tranquilizing Agents; Trifluoperazine; Vocalization, Animal

1970
REM deprivation. II. The effects on depressed patients.
    Archives of general psychiatry, 1968, Volume: 18, Issue:3

    Topics: Amitriptyline; Catecholamines; Depression; Dreams; Electroencephalography; Eye Movements; Female; Humans; Male; Middle Aged; Motor Activity; Pentobarbital; Psychological Tests; Psychotic Disorders; Sleep Deprivation; Suggestion

1968
[Correction by dihydroergotamine of arterial pressure disorders induced by psychiatric chemotherapy].
    Annales medico-psychologiques, 1968, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Amobarbital; Antidepressive Agents; Barbiturates; Butyrophenones; Chlorpromazine; Ergotamine; Humans; Hypotension; Imipramine; Methotrimeprazine; Middle Aged; Neurotic Disorders; Pentobarbital; Psychotic Disorders; Secobarbital; Tranquilizing Agents

1968
Phenytoin: similarity to tricyclic antidepressants.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlordiazepoxide; Conditioning, Operant; Cues; Desipramine; Discrimination Learning; Imipramine; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains

1983
[Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jun-30, Volume: 56, Issue:12

    Topics: Amitriptyline; Animals; Chlorpromazine; Dextroamphetamine; Meprobamate; Muscle Contraction; Muscle Relaxation; Muscles; Pentobarbital; Psychotropic Drugs; Rats; Stress, Physiological; Sulpiride

1980
[Effect of some psychotropic drugs on spontaneous electromyographic activity in the stressed rat].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jun-30, Volume: 56, Issue:12

    Topics: Amitriptyline; Animals; Chlorpromazine; Dextroamphetamine; Meprobamate; Muscles; Pentobarbital; Psychotropic Drugs; Rats; Stress, Physiological; Sulpiride

1980
Death attributed to the toxic interaction of triazolam, amitriptyline and other psychotropic drugs.
    Forensic science international, 1997, Apr-18, Volume: 86, Issue:1-2

    Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bromazepam; Drug Interactions; Ethanol; Fatal Outcome; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Male; Pentobarbital; Psychotropic Drugs; Suicide, Attempted; Triazolam

1997
[ATTEMPT AT MEASURING THE REACTION TO SOCIAL STIMULI AFTER ANTIDEPRESSIVE DRUGS (METHODICAL STUDY)].
    Activitas nervosa superior, 1964, Volume: 6

    Topics: Amitriptyline; Antidepressive Agents; Humans; Imipramine; Interpersonal Relations; Pentobarbital; Physiological Phenomena; Research; Thematic Apperception Test

1964
Relative distribution of drugs in decomposed skeletal tissue.
    Journal of analytical toxicology, 2010, Volume: 34, Issue:8

    Topics: Administration, Oral; Amitriptyline; Animals; Autopsy; Bone and Bones; Diazepam; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Male; Pentobarbital; Postmortem Changes; Ribs; Seasons; Solid Phase Extraction; Swine

2010