amitriptyline and oxycodone

amitriptyline has been researched along with oxycodone in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's7 (30.43)29.6817
2010's12 (52.17)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Pollack, CV; Sanders, DY; Severance, HW1
Kalso, E; Olkkola, KT; Pöyhiä, R; Seppälä, T1
Chipman, M; Reed, K; Vernich, L; Watson, CP1
Hu, SC; Meekins, G; Walker, M1
Faugno, D; Gaensslen, RE; Greene, P; Haner, B; Juhascik, MP; Ledray, L; Lindner, A; Negrusz, A1
Agarwal, A; Bansal, M; Conner, K1
Bansal, M; Happich, M; Klein, R; Wielage, R; Wilson, K1
Sederholm, B; Shprecher, D; Sloan, CT1
Bijur, PE; Davitt, M; Dym, AA; Esses, D; Friedman, BW; Gallagher, EJ; Holden, L; Solorzano, C1
Carpenter, CR1
Frazer, K; Stevermer, JJ1
Deuis, JR; Lewis, RJ; Vetter, I; Yin, K1
Kennedy, DJ; Kumbhare, D; Schneider, BJ1
Gottlieb, M; Njie, A1
Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM1

Reviews

3 review(s) available for amitriptyline and oxycodone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
    Spine, 2013, May-15, Volume: 38, Issue:11

    Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; Clinical Trials as Topic; Cost-Benefit Analysis; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Hydromorphone; Low Back Pain; Markov Chains; Middle Aged; Models, Economic; Naproxen; Ontario; Osteoarthritis; Outcome Assessment, Health Care; Oxycodone; Pregabalin; Pyrazoles; Quality-Adjusted Life Years; Quebec; Sulfonamides; Thiophenes

2013

Trials

4 trial(s) available for amitriptyline and oxycodone

ArticleYear
The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:6

    Topics: Administration, Oral; Adult; Amitriptyline; Chromatography, Gas; Double-Blind Method; Female; Humans; Injections, Intramuscular; Male; Morphinans; Oxycodone; Oxymorphone; Placebos; Reference Values

1992
Nortriptyline versus amitriptyline in postherpetic neuralgia: a randomized trial.
    Neurology, 1998, Volume: 51, Issue:4

    Topics: Aged; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Cross-Over Studies; Depression; Double-Blind Method; Follow-Up Studies; Herpes Zoster; Humans; Middle Aged; Neuralgia; Nortriptyline; Oxycodone; Sleep

1998
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Treatment Outcome

2015
Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain.
    CJEM, 2016, Volume: 18, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adult; Amitriptyline; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Emergency Service, Hospital; Female; Follow-Up Studies; Hospitals, Teaching; Humans; Low Back Pain; Male; Middle Aged; Naproxen; Oxycodone; Pain Measurement; Patient Satisfaction; Severity of Illness Index; Treatment Outcome; Young Adult

2016

Other Studies

16 other study(ies) available for amitriptyline and oxycodone

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Sickle cell vaso-occlusive pain crisis in adults: alternative strategies for management in the emergency department.
    Southern medical journal, 1992, Volume: 85, Issue:8

    Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics; Anemia, Sickle Cell; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hospital; Female; Humans; Ketorolac; Male; Meperidine; Oxycodone; Pain; Promethazine; Tolmetin; Trimethoprim, Sulfamethoxazole Drug Combination; Vascular Diseases

1992
Yoga neuropathy. A snoozer.
    The neurologist, 2005, Volume: 11, Issue:3

    Topics: Adult; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Disorders of Excessive Somnolence; Electromyography; Female; Fibromyalgia; Humans; Hysterectomy; Nerve Compression Syndromes; Oxycodone; Sciatic Neuropathy; Yoga

2005
An estimate of the proportion of drug-facilitation of sexual assault in four U.S. localities.
    Journal of forensic sciences, 2007, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Ambulatory Care Facilities; Amitriptyline; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Doxylamine; Dronabinol; Ethanol; Female; Flunitrazepam; Forensic Toxicology; Hair; Histamine H1 Antagonists; Humans; Hydromorphone; Male; Narcotics; Nortriptyline; Oxazepam; Oxycodone; Psychotropic Drugs; Sex Offenses; Substance Abuse Detection; United States

2007
Coma blisters with hypoxemic respiratory failure.
    Dermatology online journal, 2012, Mar-15, Volume: 18, Issue:3

    Topics: Amitriptyline; Anti-Bacterial Agents; Blister; Coma; Diazepam; Drug Therapy, Combination; Female; Humans; Mianserin; Mirtazapine; Oxycodone; Oxygen; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Pneumonia, Aspiration; Quadriplegia; Respiratory Insufficiency; Treatment Outcome; Young Adult

2012
Neuropsychiatric side effects of cyclobenzaprine.
    BMJ case reports, 2013, May-02, Volume: 2013

    Topics: Amitriptyline; Antidepressive Agents; Delirium; Humans; Male; Middle Aged; Movement Disorders; Muscle Relaxants, Central; Oxycodone; Pain; Serotonin Syndrome

2013
ACP Journal Club. In acute low back pain, adding oxycodone/acetaminophen or cyclobenzaprine to naproxen did not improve pain or function.
    Annals of internal medicine, 2016, Feb-16, Volume: 164, Issue:4

    Topics: Acetaminophen; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Low Back Pain; Male; Muscle Relaxants, Central; Naproxen; Oxycodone

2016
PURLs: More isn't better with acute low back pain treatment.
    The Journal of family practice, 2016, Volume: 65, Issue:6

    Topics: Acetaminophen; Amitriptyline; Drug Combinations; Female; Humans; Low Back Pain; Male; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Randomized Controlled Trials as Topic; Treatment Outcome

2016
Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target.
    Molecular pain, 2016, Volume: 12

    Topics: Amines; Amitriptyline; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Male; Metacarpus; Mice; Mice, Inbred C57BL; Motor Activity; Oxycodone; Pain; Pain Threshold; Proglumide; Receptor, Cholecystokinin B; Sensory Receptor Cells; Transcriptome; Weight-Bearing

2016
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: Naproxen with Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo to Treating Acute Low Back Pain: A Randomized Clinical Trial.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:6

    Topics: Acetaminophen; Amitriptyline; Humans; Low Back Pain; Naproxen; Oxycodone; Peer Review; Physiatrists

2017
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants.
    Neurology, 2022, 09-27, Volume: 99, Issue:13

    Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort Studies; Humans; Hydrocodone; Methocarbamol; Narcotic Antagonists; Neuromuscular Agents; Opiate Overdose; Orphenadrine; Oxycodone; Prescriptions; Sepsis; Substance-Related Disorders

2022