amitriptyline and nomifensine

amitriptyline has been researched along with nomifensine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199031 (77.50)18.7374
1990's2 (5.00)18.2507
2000's3 (7.50)29.6817
2010's4 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Arunotayanun, W; Dalley, JW; Gibbons, S; Huang, XP; Iversen, L; Roth, BL; Setola, V; Treble, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Daigle, L; Grof, P; Mahutte, G; Saxena, B1
Kerr, TA; Little, JC; McClelland, HA2
Habermann, W1
Burgess, CD; Montgomery, S; Turner, P; Wadsworth, J1
Guelfi, JD1
Breese, GR; Duncan, GE; Hong, JS; Mueller, RA; Paul, IA; Powell, KR1
Robertson, MM; Trimble, MR1
Acevedo, X; Muñoz, C; Yojay, R1
Barnes, JC; Costall, B; Domeney, AM; Naylor, RJ1
Borbe, HO; Dimpfel, W; Spüler, M1
Harrison, C; Hindmarch, I; Shillingford, CA1
Baltova, EJ; Shishkov, A1
Agren, H; Bjaring, B; Källström, B; Lund, M; Månsby, J; Peterson, LE; Roos, BE; Wistedt, B1
Trimble, MR1
Beckmann, H; Fleckenstein, P; Holzmüller, B2
Holmberg, G1
Ayuso Gutierez, JL; López-Ibor Aliño, JJ; Montejo Iglesias, ML; Ramons, JL1
Baltova, EJ; Shishkov, AN1
Culig, J; Ehsanullah, RS; Hallett, C; Iliopoulou, A; Matheson, I; Turner, P1
Lee, CT; Ong, SB1
Birnbom, F; Goldstein, SE; Laliberte, R1
Cassano, GB; Conti, L; Fornaro, P; Levine, J; Massimetti, G1
Ikeda, Y; Nakazawa, T; Nomura, S; Sawa, Y1
Thompson, PJ; Trimble, MR1
Cicardo, VH; Osman Dick, G1
Bickel, M1
Bonicalzi, M; Caponeri, MA; De Maio, D; Levi Minzi, A; Mellado, C; Sesso, M1
Chan, MY; Ehsanullah, R; McEwen, J; Wadsworth, J1
Fekete, MI; Herman, JP; Kanyicska, B; Szentendrei, T1
Alonso, SJ; Castellano, MA; Navarro, E; Quintero, M1

Reviews

4 review(s) available for amitriptyline and nomifensine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A review of controlled studies with nomifensine, performed outside the UK.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug Evaluation; Humans; Imipramine; Isoquinolines; Nomifensine; Placebos; Viloxazine

1977
Efficacy of tianeptine in comparative trials versus reference antidepressants. An overview.
    The British journal of psychiatry. Supplement, 1992, Issue:15

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Imipramine; Nomifensine; Personality Inventory; Thiazepines

1992
Epilepsy, antidepressants, and the role of nomifensine.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Female; Humans; Isoquinolines; Male; Nomifensine; Papio; Pilot Projects; Placebos; Rabbits; Rats; Seizures

1984

Trials

17 trial(s) available for amitriptyline and nomifensine

ArticleYear
Dopaminergic agonist nomifensine compared with amitriptyline: a double-blind clinical trial in acute primary depressions.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine

1977
Videotape technique in assessing antidepressants.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adjustment Disorders; Amitriptyline; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Humans; Nomifensine; Videotape Recording

1977
A clinical comparison of nomifensine and amitriptyline.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Amitriptyline; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Psychotic Disorders

1977
A review of controlled studies with nomifensine, performed outside the UK.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Doxepin; Drug Evaluation; Humans; Imipramine; Isoquinolines; Nomifensine; Placebos; Viloxazine

1977
Cardiovascular effects of amitriptyline, mianserin, zimelidine and nomifensine in depressed patients.
    Postgraduate medical journal, 1979, Volume: 55, Issue:648

    Topics: Adult; Amitriptyline; Blood Pressure; Dibenzazepines; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Isoquinolines; Male; Mianserin; Middle Aged; Nomifensine; Pyridines; Systole; Zimeldine

1979
The treatment of depression in patients with epilepsy. A double-blind trial.
    Journal of affective disorders, 1985, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Epilepsy; Humans; Middle Aged; Nomifensine

1985
An investigation of the effects of lofepramine, nomifensine, amitriptyline and placebo on aspects of memory and psychomotor performance related to car driving.
    International clinical psychopharmacology, 1988, Volume: 3, Issue:2

    Topics: Adult; Amitriptyline; Automobile Driving; Dibenzazepines; Female; Flicker Fusion; Humans; Hypnotics and Sedatives; Lofepramine; Memory; Middle Aged; Nomifensine; Psychomotor Performance; Reaction Time; Sleep; Visual Perception

1988
Nomifensine and amitriptyline in the treatment of depression. A multi-centre double-blind comparison.
    Acta psychiatrica Scandinavica, 1983, Volume: 68, Issue:3

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Fatigue; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Psychiatric Status Rating Scales

1983
Epilepsy, antidepressants, and the role of nomifensine.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Female; Humans; Isoquinolines; Male; Nomifensine; Papio; Pilot Projects; Placebos; Rabbits; Rats; Seizures

1984
Clinical investigations into antidepressive mechanisms. II. Dexamethasone suppression test predicts response to nomifensine or amitriptyline.
    Acta psychiatrica Scandinavica, 1984, Volume: 70, Issue:4

    Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Dexamethasone; Double-Blind Method; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Receptors, Cholinergic

1984
Critical flicker fusion (CFF) test for sedative effect of antidepressants.
    Acta psychiatrica Scandinavica. Supplementum, 1981, Volume: 290

    Topics: Adult; Amitriptyline; Antidepressive Agents; Arousal; Brompheniramine; Doxepin; Female; Flicker Fusion; Humans; Hypnotics and Sedatives; Imipramine; Male; Nomifensine; Zimeldine

1981
A double-blind clinical comparison between nomifensine and amitriptyline in the treatment of endogenous depressions.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adult; Age Factors; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Psychiatric Status Rating Scales; Sex Factors

1982
A clinical pharmacological comparison of diclofensine (Ro 8-4650) with nomifensine and amitriptyline in normal human volunteers.
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Electrocardiography; Flicker Fusion; Hemodynamics; Hormones; Humans; Isoquinolines; Male; Nomifensine; Pupil; Reaction Time; Salivation

1983
A double-blind comparison of nomifensine and amitriptyline in the treatment of depression.
    Acta psychiatrica Scandinavica, 1981, Volume: 63, Issue:3

    Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine

1981
Nomifensine in the treatment of depressed geriatric patients.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:7

    Topics: Adjustment Disorders; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Psychiatric Status Rating Scales

1982
A double-blind clinical trial of nomifensine vs. amitriptyline in depressed patients.
    Pharmacopsychiatria, 1982, Volume: 15, Issue:3

    Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Flurazepam; Hospitals, Psychiatric; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; Psychiatric Status Rating Scales; Random Allocation

1982
A comparison of the pharmacodynamic profiles of nomifensine and amitriptyline in normal subjects.
    British journal of clinical pharmacology, 1980, Volume: 9, Issue:3

    Topics: Amitriptyline; Blood Platelets; Dopamine; Humans; Hypnotics and Sedatives; Isoquinolines; Kinetics; Male; Nomifensine; Reaction Time; Salivation; Serotonin; Time Factors

1980

Other Studies

21 other study(ies) available for amitriptyline and nomifensine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.
    Bioorganic & medicinal chemistry letters, 2013, Jun-01, Volume: 23, Issue:11

    Topics: Allyl Compounds; HEK293 Cells; Humans; Indoles; Magnetic Resonance Spectroscopy; Molecular Conformation; Propylamines; Protein Binding; Psychotropic Drugs; Receptors, Serotonin; Serotonin Receptor Agonists; Spectrophotometry, Ultraviolet; Tryptamines

2013
Regionally specific neural adaptation of beta adrenergic and 5-hydroxytryptamine2 receptors after antidepressant administration in the forced swim test and after chronic antidepressant drug treatment.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Imipramine; Male; Nomifensine; Pargyline; Physical Exertion; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Swimming

1988
Use of antidepressant drugs in the study of the role of biogenic amines in ethanol narcosis.
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1986, Volume: 36, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Central Nervous System; Depression, Chemical; Drug Interactions; Ethanol; Female; Fenclonine; Imipramine; Male; Mice; Nomifensine; Norepinephrine; Serotonin

1986
Lithium and bupropion antagonise the phasic changes in locomotor activity caused by dopamine infused into the rat nucleus accumbens.
    Psychopharmacology, 1986, Volume: 89, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Bupropion; Dopamine Antagonists; Female; Imipramine; Lithium; Motor Activity; Nomifensine; Nucleus Accumbens; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei

1986
Monitoring of the effects of antidepressant drugs in the freely moving rat by radioelectroencephalography (tele-stereo-EEG).
    Neuropsychobiology, 1988, Volume: 19, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Arousal; Brain; Dextroamphetamine; Doxepin; Electroencephalography; Haloperidol; Imipramine; Lysergic Acid Diethylamide; Male; Microcomputers; Nomifensine; Rats; Rats, Inbred F344; Signal Processing, Computer-Assisted; Telemetry

1988
Separation and identification of the antidepressants Imipramine, amitriptyline and Nomifensine by thin layer chromatography.
    Folia medica, 1983, Volume: 25, Issue:3

    Topics: Amitriptyline; Antipsychotic Agents; Chromatography, Thin Layer; Diazepam; Humans; Imipramine; Isoquinolines; Nomifensine; Phenothiazines; Solvents

1983
Dexamethasone suppression test predicts response to nomifensine or amitriptyline.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: Amitriptyline; Depressive Disorder; Dexamethasone; Double-Blind Method; Humans; Isoquinolines; Nomifensine

1984
Microcrystalloscopic reactions for identification of the antidepressants imipramine, amitriptyline and nomifensine.
    Folia medica, 1982, Volume: 24, Issue:2

    Topics: Amitriptyline; Chemical Phenomena; Chemistry; Crystallization; Imipramine; Isoquinolines; Nomifensine

1982
The effects of antidepressants on the autonomic nervous system--a current investigation.
    Journal of neural transmission, 1982, Volume: 54, Issue:1-2

    Topics: Adult; Amitriptyline; Arousal; Autonomic Nervous System; Dopamine beta-Hydroxylase; Galvanic Skin Response; Heart Rate; Humans; Isoquinolines; Male; Nomifensine; Respiration

1982
Non-MAOI antidepressant drugs and cognitive functions: a review.
    Psychological medicine, 1982, Volume: 12, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Cognition; Cognition Disorders; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imipramine; Mianserin; Motor Skills; Nomifensine; Reaction Time; Viloxazine

1982
[Pressor response to the stimulation of peripheral sympathetic nerves and the posterior hypothalamus in the presence of tricyclic antidepressive agents and nomifensine in dogs].
    Acta physiologica latino americana, 1982, Volume: 32, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Clomipramine; Dogs; Electric Stimulation; Hypothalamus; Hypothalamus, Posterior; Imipramine; Isoquinolines; Nomifensine; Peripheral Nerves

1982
Antiulcer effects of nomifensine, a new antidepressant, on stress-induced ulcers in the rat.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:1

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Gastric Mucosa; Humans; Immersion; Isoquinolines; Male; Nomifensine; Pylorus; Rats; Restraint, Physical; Stomach Ulcer; Stress, Psychological

1980
Evaluation of the clinical efficacy of single daily doses of antidepressants.
    Progress in neuro-psychopharmacology, 1980, Volume: 4, Issue:6

    Topics: Adult; Amitriptyline; Antidepressive Agents; Depression; Drug Administration Schedule; Half-Life; Humans; Male; Middle Aged; Nomifensine; Psychiatric Status Rating Scales

1980
Effects of reserpine and antidepressants on dopamine and DOPAC (3,4-dihydroxyphenylacetic acid) concentrations in the striatum, olfactory tubercle and median eminence of rats.
    European journal of pharmacology, 1980, Jun-27, Volume: 64, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents; Corpus Striatum; Dopamine; Drug Interactions; Female; Hypothalamo-Hypophyseal System; Median Eminence; Nomifensine; Olfactory Bulb; Phenylacetates; Rats; Reserpine

1980
Action of antidepressant drugs on maternal stress-induced hypoactivity in female rats.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationship, Drug; Exercise Test; Female; Imipramine; Nomifensine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Stress, Mechanical

1999