amitriptyline and naproxen

amitriptyline has been researched along with naproxen in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's3 (11.11)18.2507
2000's7 (25.93)29.6817
2010's13 (48.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hering, R; Steiner, TJ1
Felson, DT; Goldenberg, DL; Simms, RW1
Arvidsson, T1
Dinerman, H; Felson, DT; Goldenberg, DL1
Damasio, H1
Banerjee, T; Kishore, N; Singh, SK1
Bansal, M; Happich, M; Klein, R; Wielage, R; Wilson, K1
Bijur, PE; Davitt, M; Dym, AA; Esses, D; Friedman, BW; Gallagher, EJ; Holden, L; Solorzano, C1
Carpenter, CR1
Frazer, K; Stevermer, JJ1
Kennedy, DJ; Kumbhare, D; Schneider, BJ1
Gottlieb, M; Njie, A1

Reviews

5 review(s) available for amitriptyline and naproxen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug management of adult vascular headaches (migraine and cluster headache): Part II--Prevention and attacks.
    Iowa medicine : journal of the Iowa Medical Society, 1984, Volume: 74, Issue:12

    Topics: Adult; Amitriptyline; Belladonna Alkaloids; Cluster Headache; Cyproheptadine; Drug Combinations; Ergotamine; Ergotamines; Female; Humans; Lithium; Lithium Carbonate; Male; Methysergide; Migraine Disorders; Monoamine Oxidase Inhibitors; Naproxen; Phenobarbital; Pregnancy; Pregnancy Complications; Propranolol; Vascular Headaches

1984
Cost-effectiveness of duloxetine in chronic low back pain: a Quebec societal perspective.
    Spine, 2013, May-15, Volume: 38, Issue:11

    Topics: Age Factors; Aged; Amitriptyline; Analgesics; Cardiovascular Diseases; Celecoxib; Chronic Disease; Clinical Trials as Topic; Cost-Benefit Analysis; Duloxetine Hydrochloride; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Hydromorphone; Low Back Pain; Markov Chains; Middle Aged; Models, Economic; Naproxen; Ontario; Osteoarthritis; Outcome Assessment, Health Care; Oxycodone; Pregabalin; Pyrazoles; Quality-Adjusted Life Years; Quebec; Sulfonamides; Thiophenes

2013

Trials

5 trial(s) available for amitriptyline and naproxen

ArticleYear
Abrupt outpatient withdrawal of medication in analgesic-abusing migraineurs.
    Lancet (London, England), 1991, Jun-15, Volume: 337, Issue:8755

    Topics: Adult; Amitriptyline; Analgesics; Caffeine; Ergotamine; Evaluation Studies as Topic; Female; Follow-Up Studies; Headache; Humans; Male; Middle Aged; Migraine Disorders; Naproxen; Outpatients; Substance Withdrawal Syndrome; Substance-Related Disorders

1991
Development of preliminary criteria for response to treatment in fibromyalgia syndrome.
    The Journal of rheumatology, 1991, Volume: 18, Issue:10

    Topics: Amitriptyline; Double-Blind Method; Fibromyalgia; Humans; Naproxen; Regression Analysis

1991
A randomized, controlled trial of amitriptyline and naproxen in the treatment of patients with fibromyalgia.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:11

    Topics: Amitriptyline; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Fibromyalgia; Humans; Naproxen; Placebos; Random Allocation; Terminology as Topic

1986
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Treatment Outcome

2015
Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain.
    CJEM, 2016, Volume: 18, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adult; Amitriptyline; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Emergency Service, Hospital; Female; Follow-Up Studies; Hospitals, Teaching; Humans; Low Back Pain; Male; Middle Aged; Naproxen; Oxycodone; Pain Measurement; Patient Satisfaction; Severity of Illness Index; Treatment Outcome; Young Adult

2016

Other Studies

17 other study(ies) available for amitriptyline and naproxen

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of drug-protein binding on trace enrichment of drugs in blood plasma on short precolumns.
    Journal of chromatography, 1988, May-20, Volume: 439, Issue:2

    Topics: Amitriptyline; Blood Proteins; Chemical Phenomena; Chemistry, Physical; Humans; Hydrogen-Ion Concentration; Naproxen; Nortriptyline; Pharmaceutical Preparations; Phosphoric Acids; Protein Binding; Serum Albumin

1988
New "triptans" and other drugs for migraine.
    The Medical letter on drugs and therapeutics, 1998, Oct-09, Volume: 40, Issue:1037

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents

1998
Binding of naproxen and amitriptyline to bovine serum albumin: biophysical aspects.
    The journal of physical chemistry. B, 2006, Nov-30, Volume: 110, Issue:47

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Calorimetry; Circular Dichroism; Hydrophobic and Hydrophilic Interactions; Ligands; Naproxen; Protein Conformation; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Static Electricity; Surface-Active Agents; Temperature

2006
ACP Journal Club. In acute low back pain, adding oxycodone/acetaminophen or cyclobenzaprine to naproxen did not improve pain or function.
    Annals of internal medicine, 2016, Feb-16, Volume: 164, Issue:4

    Topics: Acetaminophen; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Low Back Pain; Male; Muscle Relaxants, Central; Naproxen; Oxycodone

2016
PURLs: More isn't better with acute low back pain treatment.
    The Journal of family practice, 2016, Volume: 65, Issue:6

    Topics: Acetaminophen; Amitriptyline; Drug Combinations; Female; Humans; Low Back Pain; Male; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Randomized Controlled Trials as Topic; Treatment Outcome

2016
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: Naproxen with Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo to Treating Acute Low Back Pain: A Randomized Clinical Trial.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:6

    Topics: Acetaminophen; Amitriptyline; Humans; Low Back Pain; Naproxen; Oxycodone; Peer Review; Physiatrists

2017