amitriptyline and naloxone

amitriptyline has been researched along with naloxone in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's2 (7.41)18.2507
2000's9 (33.33)29.6817
2010's9 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
de Ceballos, ML; de Felipe, MC; Fuentes, JA1
Heath, A; Knudsen, K; Ricksten, SE1
Adithan, C; Bapna, JS; Shashindran, CH; Sivagnanam, G; Swain, R1
Lewit, T1
Kamei, C; Shimomura, K; Ueki, S1
Gaillard-Plaza, G; Lopez-Timoneda, F; Montastruc, JL1
Silverstone, T1
Gray, AM; Sewell, RD; Spencer, PS1
Ardid, D; Chapuy, E; Eschalier, A; Jourdan, D; Le Bars, D1
Bartolini, A; Galeotti, N; Ghelardini, C1
Pettersen, VL; Raimundo, JM; Sudo, RT; Trachez, MM; Zapata-Sudo, G1
Ari, M; Duru, M; Oktar, S1
Ita, K; Ospina, J; Simon, L1

Reviews

5 review(s) available for amitriptyline and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pulmonary diseases due to drugs. II].
    Harefuah, 1974, Jun-16, Volume: 86, Issue:12

    Topics: Amines; Amitriptyline; Beclomethasone; Drug-Related Side Effects and Adverse Reactions; Heroin; Humans; Hydantoins; Lung Diseases; Methadone; Naloxone; Oxazoles; Pneumonia, Aspiration; Respiratory Therapy; Sulfasalazine; Ventilators, Mechanical

1974
Psychopharmacology of hunger and food intake in humans.
    Pharmacology & therapeutics, 1982, Volume: 19, Issue:3

    Topics: Amitriptyline; Amphetamine; Appetite Depressants; Chlorpromazine; Cholecystokinin; Cyproheptadine; Eating; Feeding Behavior; Fenfluramine; Humans; Hunger; Insulin; Lithium; Naloxone

1982

Other Studies

22 other study(ies) available for amitriptyline and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Hypoalgesia induced by antidepressants in mice: a case for opioids and serotonin.
    European journal of pharmacology, 1986, Jun-17, Volume: 125, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Dibenzazepines; Drug Tolerance; Endorphins; Fenclonine; Imipramine; Iprindole; Male; Methysergide; Mice; Mice, Inbred ICR; Naloxone; Pain; Protease Inhibitors; Serotonin

1986
Effects of naloxone and verapamil in experimental amitriptyline poisoning in rats.
    Journal of toxicology. Clinical toxicology, 1988, Volume: 26, Issue:5-6

    Topics: Amitriptyline; Animals; Antidotes; Blood Pressure; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Naloxone; Rats; Rats, Inbred Strains; Verapamil

1988
Potentiation of clonidine analgesia by amitriptyline.
    Indian journal of experimental biology, 1986, Volume: 24, Issue:4

    Topics: Amitriptyline; Analgesia; Animals; Clonidine; Drug Synergism; Male; Mice; Naloxone; Yohimbine

1986
Significance of withdrawal jumping response in predicting physical dependence in mice.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome

1973
[Endomorphins and experimental analgesic action of amitriptyline].
    Revue neurologique, 1983, Volume: 139, Issue:8-9

    Topics: Amitriptyline; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Male; Naloxone; Nociceptors; Rats; Rats, Inbred Strains

1983
The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds.
    British journal of pharmacology, 1998, Volume: 124, Issue:4

    Topics: Abdominal Muscles; Acetic Acid; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Male; Maprotiline; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Neurotransmitter Uptake Inhibitors; Opioid Peptides; Pain Measurement; Paroxetine; Protease Inhibitors; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Thiorphan

1998
Effect of analgesics on audible and ultrasonic pain-induced vocalization in the rat.
    Life sciences, 1998, Volume: 63, Issue:20

    Topics: Amitriptyline; Analgesics; Animals; Aspirin; Cricetinae; Electric Stimulation; Male; Morphine; Naloxone; Pain; Rats; Rats, Sprague-Dawley; Ultrasonics; Vocalization, Animal

1998
Antinociception induced by amitriptyline and imipramine is mediated by alpha2A-adrenoceptors.
    Japanese journal of pharmacology, 2000, Volume: 82, Issue:2

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Imidazoles; Imipramine; Indoles; Isoindoles; Male; Mice; Naloxone; Organophosphorus Compounds; Receptors, Adrenergic, alpha-2; Yohimbine

2000
The synergistic interaction between morphine and maprotiline after intrathecal injection in rats.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Injections, Spinal; Male; Maprotiline; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Time Factors; Yohimbine

2009
Amitriptyline and tianeptine poisoning treated by naloxone.
    Human & experimental toxicology, 2010, Volume: 29, Issue:9

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Drug Overdose; Female; Humans; Naloxone; Narcotic Antagonists; Thiazepines; Treatment Outcome

2010
Prediction of in-vivo iontophoretic drug release data from in-vitro experiments-insights from modeling.
    Mathematical biosciences, 2015, Volume: 270, Issue:Pt A

    Topics: Amitriptyline; Animals; Computer Simulation; Dexamethasone; Drug Liberation; Growth Hormone-Releasing Hormone; Guinea Pigs; Humans; In Vitro Techniques; Iontophoresis; Mathematical Concepts; Models, Biological; Naloxone; Rats; Skin Absorption

2015