amitriptyline and moclobemide

amitriptyline has been researched along with moclobemide in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's13 (46.43)18.2507
2000's6 (21.43)29.6817
2010's8 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Alda, M; Bakish, D; Ellis, J; Lapierre, Y; Wiens, A1
Adena, M; Evans, L; George, T; Johnson, G; Mitchell, P; O'Sullivan, B1
Bakish, D; Bradwejn, J; Bulger, L; McClure, J; Nair, N; Remick, R1
Fraser, AR; Menkes, DB; Mullen, PE; Newburn, GM1
Beckers, G; Berger, M; de Bleeker, E; Faidherbe, J; Hellstern, K; Jaunes, C; Sieben, G; Vereecken, A; Ward, J; Wolfrum, C1
Eichler, HG; Fischbach, R; Gasic, S; Korn, A1
Friess, E; Grasser, A; Holsboer, F; Wiedemann, K1
Fawcett, JP; Menkes, DB; Patel, PP1
Bradwejn, J; Engelsmann, F; Kusalic, M1
Fairweather, DB; Hindmarch, I; Kerr, JS1
Stanton, J1
Angst, J; Delini-Stula, A; Mikkelsen, H1
Iakovlev, VA1
Hannonen, P; Isomeri, R; Malminiemi, K; Roponen, P; Yli-Kerttula, U1
van de Laar, MA; Zijlstra, TR1
Bejar, C; Drigues, N; Poltyrev, T; Weinstock, M; Youdim, MB1
Koval'chuk, VV1
Fisar, Z; Hroudová, J; Raboch, J1
Poleszak, E; Serefko, A; Wlaź, P; Wróbel, A1
Barbui, C; Cipriani, A; Furukawa, TA; Hayasaka, Y; Leucht, S; Magni, LR; Ogawa, Y; Purgato, M; Takeshima, N1

Reviews

2 review(s) available for amitriptyline and moclobemide

ArticleYear
Steroid effects on central neurons and implications for psychiatric and neurological disorders.
    Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 746

    Topics: Adrenocorticotropic Hormone; Amitriptyline; Benzamides; Brain; Corticotropin-Releasing Hormone; Dexamethasone; Electroencephalography; HIV Infections; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Moclobemide; Mood Disorders; Multiple Sclerosis; Neurons; Pituitary-Adrenal System; Sleep; Stress Disorders, Post-Traumatic; Stress, Psychological; Wounds and Injuries

1994
Therapeutic efficacy of antidepressants in agitated anxious depression--a meta-analysis of moclobemide studies.
    Journal of affective disorders, 1995, Oct-09, Volume: 35, Issue:1-2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Benzamides; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Imipramine; Male; Maprotiline; Mianserin; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Personality Assessment; Psychomotor Agitation; Treatment Outcome

1995

Trials

10 trial(s) available for amitriptyline and moclobemide

ArticleYear
A double-blind placebo-controlled comparison of moclobemide and amitriptyline in the treatment of depression.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1992, Volume: 37 Suppl 1

    Topics: Adult; Amitriptyline; Benzamides; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales

1992
An Australian multicentre study of moclobemide versus amitriptyline in the treatment of depression.
    The Australian and New Zealand journal of psychiatry, 1992, Volume: 26, Issue:3

    Topics: Adult; Aged; Amitriptyline; Anxiety Disorders; Benzamides; Depressive Disorder; Double-Blind Method; Drug Monitoring; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Personality Inventory

1992
A comparison of moclobemide, amitriptyline and placebo in depression: a Canadian multicentre study.
    Psychopharmacology, 1992, Volume: 106 Suppl

    Topics: Adult; Amitriptyline; Antidepressive Agents; Benzamides; Body Weight; Canada; Depressive Disorder; Female; Humans; Male; Middle Aged; Moclobemide; Psychiatric Status Rating Scales; Single-Blind Method

1992
A double blind trial of moclobemide versus amitriptyline in the treatment of depressive disorders.
    The Australian and New Zealand journal of psychiatry, 1990, Volume: 24, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents; Benzamides; Blood Pressure; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Prospective Studies; Psychiatric Status Rating Scales

1990
Moclobemide versus amitriptyline in the treatment of depression: two small double-blind multicentre studies in Belgium.
    Acta psychiatrica Scandinavica. Supplementum, 1990, Volume: 360

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Belgium; Benzamides; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Psychiatric Status Rating Scales

1990
Thyroid functioning during treatment for depression.
    Journal of psychiatry & neuroscience : JPN, 1993, Volume: 18, Issue:5

    Topics: Adult; Amitriptyline; Benzamides; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Personality Inventory; Thyroid Function Tests; Thyroid Hormones

1993
The effects of moclobemide on psychomotor performance and cognitive function.
    International clinical psychopharmacology, 1993,Spring, Volume: 8, Issue:1

    Topics: Adult; Amitriptyline; Analysis of Variance; Benzamides; Cognition; Double-Blind Method; Humans; Male; Memory; Moclobemide; Monoamine Oxidase Inhibitors; Psychological Tests; Psychomotor Performance; Reaction Time; Sleep

1993
The Australian multicentre moclobemide trial.
    The Australian and New Zealand journal of psychiatry, 1993, Volume: 27, Issue:1

    Topics: Amitriptyline; Australia; Benzamides; Bias; Depressive Disorder; Humans; Moclobemide; Monoamine Oxidase Inhibitors

1993
A randomized, double-blind, placebo-controlled study of moclobemide and amitriptyline in the treatment of fibromyalgia in females without psychiatric disorder.
    British journal of rheumatology, 1998, Volume: 37, Issue:12

    Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Benzamides; Disability Evaluation; Double-Blind Method; Female; Fibromyalgia; Humans; Mental Disorders; Middle Aged; Moclobemide; Patient Compliance; Placebos; Quality of Life

1998
[Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].
    Voprosy onkologii, 2007, Volume: 53, Issue:6

    Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain Neoplasms; Depression; Doxepin; Emotions; Female; Humans; Male; Maprotiline; Middle Aged; Moclobemide; Mood Disorders; Neurosurgical Procedures; Nialamide; Sertraline; Thiazepines; Trazodone; Treatment Outcome

2007

Other Studies

16 other study(ies) available for amitriptyline and moclobemide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Moclobemide, a new reversible MAO inhibitor--interaction with tyramine and tricyclic antidepressants in healthy volunteers and depressive patients.
    Psychopharmacology, 1986, Volume: 88, Issue:2

    Topics: Adult; Amitriptyline; Benzamides; Blood Pressure; Cheese; Depressive Disorder; Drug Interactions; Female; Heart Rate; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Tyramine; Wine

1986
Antidepressant treatment and chemical sympathectomy fail to modulate alpha 1-adrenoceptor sensitivity in mouse eye.
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Administration, Topical; Amitriptyline; Animals; Antidepressive Agents; Benzamides; Desipramine; Down-Regulation; Fluoxetine; Injections, Intraperitoneal; Male; Methoxamine; Mice; Moclobemide; Oxidopamine; Phentolamine; Phenylephrine; Prazosin; Pupil; Receptors, Adrenergic, alpha-1; Sympathectomy, Chemical; Time Factors

1993
[The comparative efficacy of Aurorix and amitriptyline in treating depressions].
    Voenno-meditsinskii zhurnal, 1997, Volume: 318, Issue:4

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Depression; Depressive Disorder; Drug Evaluation; Female; Humans; Male; Middle Aged; Moclobemide

1997
The lack of a placebo effect in a trial of fluoxetine in the treatment of fibromyalgia.
    The American journal of medicine, 2002, Volume: 113, Issue:7

    Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-Generation; Female; Fibromyalgia; Fluoxetine; Humans; Moclobemide; Placebo Effect; Randomized Controlled Trials as Topic; Treatment Outcome

2002
cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:12

    Topics: Activating Transcription Factor 1; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Clorgyline; Cyclic AMP; DNA Primers; DNA-Binding Proteins; DNA, Complementary; Hippocampus; Male; Moclobemide; Oligonucleotide Array Sequence Analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factors

2003
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:5

    Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride

2010
The depressogenic-like effect of acute and chronic treatment with dexamethasone and its influence on the activity of antidepressant drugs in the forced swim test in adult mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Oct-03, Volume: 54

    Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Depression; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Imipramine; Male; Mianserin; Mice; Moclobemide; Motor Activity; Neuropsychological Tests; Swimming; Thiazepines

2014
Dose equivalents of antidepressants: Evidence-based recommendations from randomized controlled trials.
    Journal of affective disorders, 2015, Jul-15, Volume: 180

    Topics: Adult; Amitriptyline; Antidepressive Agents; Bupropion; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Evidence-Based Medicine; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Moclobemide; Nortriptyline; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

2015