amitriptyline and methyldopa

amitriptyline has been researched along with methyldopa in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (45.45)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (22.73)	29.6817
2010's	7 (31.82)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Sheffield, LT; Sweet, RL	1
Klempel, K	1
Duvoisin, RC; Yahr, MD	1
Turkington, RW	1
Presthus, J	1
Haefely, W	1
de Levin, RW; Levin, E; Puig, OR	1
Harris, DB; Stiff, JL	1
Hall, ED	1
WHITE, AG	1

Reviews

4 review(s) available for amitriptyline and methyldopa

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug therapy of parkinsonism. The New England journal of medicine, 1972, Jul-06, Volume: 287, Issue:1 Topics: Amantadine; Amitriptyline; Amphetamine; Antiparkinson Agents; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Phenothiazines	1972
[Other trials with drug therapy in parkinsonism]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28 Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine	1973
[Drugs with effect on the adrenergic nerve fiber]. Pharmaceutica acta Helvetiae, 1968, Volume: 43, Issue:12 Topics: Aminocaproates; Amitriptyline; Amphetamine; Bretylium Compounds; Chlorpromazine; Disulfiram; Dopamine; Ephedrine; Guanethidine; Humans; Imipramine; Mental Disorders; Metaraminol; Methyldopa; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Octopamine; Prenylamine; Reserpine; Sympathetic Nervous System; Sympathomimetics; Tetrabenazine; Tyramine; Vascular Diseases	1968

Trials

1 trial(s) available for amitriptyline and methyldopa

Article	Year
Prolactin secretion in patients treated with various drugs: phenothiazines, tricyclic antidepressants, reserpine, and methyldopa. Archives of internal medicine, 1972, Volume: 130, Issue:3 Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Clinical Trials as Topic; Fluphenazine; Humans; Hypertension; Imipramine; Injections, Intramuscular; Methyldopa; Phenothiazines; Prolactin; Promazine; Reserpine; Stimulation, Chemical; Time Factors; Tranquilizing Agents	1972

Article

Year

Prolactin secretion in patients treated with various drugs: phenothiazines, tricyclic antidepressants, reserpine, and methyldopa.

Archives of internal medicine, 1972, Volume: 130, Issue:3

Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Clinical Trials as Topic; Fluphenazine; Humans; Hypertension; Imipramine; Injections, Intramuscular; Methyldopa; Phenothiazines; Prolactin; Promazine; Reserpine; Stimulation, Chemical; Time Factors; Tranquilizing Agents

1972

Other Studies

17 other study(ies) available for amitriptyline and methyldopa

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Myocardial infarction after exercise-induced electrocardiographic changes in a patient with variant angina pectoris. The American journal of cardiology, 1974, May-20, Volume: 33, Issue:6 Topics: Amitriptyline; Angina Pectoris; Arteriosclerosis; Catheterization; Diabetes Complications; Electrocardiography; Exercise Test; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Infarction; Nitroglycerin	1974
[Partial neuronal denervation as treatment principle of affective disorders. A preliminary report]. Der Nervenarzt, 1974, Volume: 45, Issue:6 Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Brain; Catecholamines; Depression; Female; Humans; Male; Methyldopa; Middle Aged; Models, Neurological; Neurons; Remission, Spontaneous; Synaptic Transmission	1974
Increased risk for cancer of the breast due to previous medication. Archiv fur Geschwulstforschung, 1984, Volume: 54, Issue:2 Topics: 20-alpha-Dihydroprogesterone; Adult; Aged; Amitriptyline; Amphetamines; Breast Neoplasms; Cimetidine; Contraceptive Agents; Estradiol; Female; Humans; Methyldopa; Middle Aged; Phenothiazines; Prolactin; Psychotropic Drugs; Quinestrol; Risk; Time Factors	1984
Clonidine withdrawal complicated by amitriptyline therapy. Anesthesiology, 1983, Volume: 59, Issue:1 Topics: Aged; Amitriptyline; Anxiety; Clonidine; Female; Humans; Hypertension; Intraoperative Care; Methyldopa; Nitroprusside; Postoperative Care; Propranolol; Substance Withdrawal Syndrome; Tachycardia	1983
Non-serotonergic depression of spinal monosynaptic reflex transmission by 5-hydroxytryptophan. Neuropharmacology, 1981, Volume: 20, Issue:2 Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Cats; Cinanserin; Cyproheptadine; Electric Stimulation; Female; Male; Methyldopa; Neurons, Afferent; Reflex, Monosynaptic; Serotonin; Spinal Cord	1981
METHYLDOPA AND AMITRIPTYLINE. Lancet (London, England), 1965, Aug-28, Volume: 2, Issue:7409 Topics: Amitriptyline; Depression; Depressive Disorder; Drug Synergism; Drug Therapy; Hypertension; Methyldopa; Toxicology; Tremor	1965