Compounds > amitriptyline

amitriptyline and mecamylamine

amitriptyline has been researched along with mecamylamine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lagerquist, B; Morgan, GM; Stone, CA; Torchiana, ML; Wenger, HC1
Beech, RD; Caldarone, BJ; Cleary, MA; Harrist, A; King, SL; Picciotto, MR1

Reviews

1 review(s) available for amitriptyline and mecamylamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for amitriptyline and mecamylamine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Pharmacological antagonism of the toxic manifestations of amitriptyline and protriptyline in dogs.
    Toxicology and applied pharmacology, 1972, Volume: 21, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Dibenzocycloheptenes; Dogs; Drug Antagonism; Electrocardiography; Heart Rate; Mecamylamine; Methylamines; Physostigmine; Propranolol; Propylamines; Pyridostigmine Bromide

1972
High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation.
    Biological psychiatry, 2004, Nov-01, Volume: 56, Issue:9

    Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bromodeoxyuridine; Cell Count; Cell Proliferation; Dose-Response Relationship, Drug; Drosophila Proteins; Drug Interactions; Helplessness, Learned; Hindlimb Suspension; Hippocampus; Immunohistochemistry; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotinic Antagonists; Nortriptyline; Receptors, Nicotinic; Swimming

2004