amitriptyline and lidocaine

amitriptyline has been researched along with lidocaine in 68 studies

Research

Studies (68)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (19.12)	18.7374
1990's	5 (7.35)	18.2507
2000's	22 (32.35)	29.6817
2010's	22 (32.35)	24.3611
2020's	6 (8.82)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Chiang, GH; Unger, SH	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Moffat, AC	1
Kingston, ME	1
Cravey, RH; Garriott, JC; Lundberg, GD; Reynolds, PC; Shaw, RF	1
Persson, G; Siwers, B	1
Barber, MJ; Grant, AO; Starmer, CF	1
Nattel, S	1
Adams, RN; Kent, TA; Nagy, G; Oke, AF; Preskorn, SH	1
Jensen, AM	1
Bennett, JC; Dodson, WH; McBride, WW	1
Mittleman, M; Nattel, S	1
Shea, JJ	1
Heath, A; Löfström, B; Mårtensson, E	1
Abrahamsson, J; Knudsen, K	1
McKay, M	1
Campos, E; Chayet, L; Collados, L; García, L; Kettlun, AM; Traverso-Cori, A; Valenzuela, MA	1
Abdi, S; Chung, JM; Lee, DH	1
Maneksha, FR; Mirza, H; Poppers, PJ	1
Bräu, ME; Dreimann, M; Hempelmann, G; Olschewski, A; Vogel, W	1
Anthony, DC; Gerner, P; Khan, M; Mujtaba, M; Sudoh, Y; Vlassakov, K; Wang, GK	1
Ecoffey, C; Estèbe, JP; Gentili, ME; Le Corre, P; Leduc, C; Moulinoux, JP	1
Gerner, P; Haderer, A; Kao, G; Srinivasa, V; Wang, GK	1
Abdi, S; Gerner, P; Haderer, AE; Mujtaba, M; Narang, S; Pertl, C; Srinivasa, V; Sudoh, Y; Wang, GK	1
Mark, WJ; Reuben, I; Shvartzman, P; Silviu, B	1
Gerner, P; Haller, I; Hung, YC; Kau, YC; Klimaschewski, L; Lirk, P; Myers, RR	1
Leffler, A; Mohapatra, DP; Nau, C; Reiprich, A	1
Ho, KY; Huh, BK; Miller, EJ; White, WD; Yeh, CC	1
Algren, DA; Sutter, ME	1
Andriolo, RB; Atallah, AN; da Silva, EM; El Dib, R; Grossmann, E; Januzzi, E; Leite, FM	1
Issy, AM; Sakata, RK; Vlainich, R	1
Gerbis, B; Gillis, D; Holwerda, E; Uzaraga, I; Wai, E	1
Aoki, T; Enomoto, R; Matsuoka, N; Shimoshige, Y; Tsukamoto, M	1
Artiukov, OP; Kornilova, LE; Sokov, EL	1
Esin, OR; Esin, RG; Sitnova, MA	1
Burris, KD; Cerne, R; Krambis, MJ; Priest, BT; Wakulchik, M	1
Cioroiu, BI; Cioroiu, ME; Grigoriu, IC; Lazar, MI; Lupuleasa, R; Niculaua, M	1
Chen, F; Chen, J; Huang, F; Tu, W; Zheng, T; Zheng, X	1
Albertoni Giraldes, AL; Brunialti, MK; Leal, PD; Sakata, RK; Salomão, R	1
Gibbs, LM; Lindsay, TJ; Snyder, MJ	1
Berenato, F; Chan, YH; Grossman, SK; Korbutov, J; Lavery, MJ; Lee, HG; Valdes-Rodriguez, R; Yosipovitch, G	1
Jaller, JA; Yosipovitch, G	1
Burke, NS; Costa, AP; Court, MH; Mealey, KL; Villarino, NF	1
Chen, P; Chen, X; Gao, F; Gong, C; Liao, Y; Lin, M; Zhang, H; Zheng, T; Zheng, X	1
Acosta, MDC; Belmonte, C; Gallar, J; Luna, C; Meseguer, V; Mizerska, K; Quirce, S	1
Earnest, R; Goodman, MD; McGlone, E; Morris, MC; Singer, KE; Stevens-Topie, S; Wallen, TE	1
Bracke, F; Frieling, H; Leffler, A	1
Glayzer, EJ; Glayzer, JE; He, Y; Kobak, WH; Li, H; McFarlin, BL; Schlaeger, JM; Takakura, N; Takayama, M; Villegas-Downs, M; Yajima, H	1

Reviews

6 review(s) available for amitriptyline and lidocaine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Medical treatment of tinnitus. The American journal of otology, 1984, Volume: 5, Issue:6 Topics: Amitriptyline; Anti-Arrhythmia Agents; Auditory Pathways; Drug Combinations; Humans; Lidocaine; Pain; Perphenazine; Tinnitus; Tocainide	1984
Local approaches to the pain of pressure ulcers. Ostomy/wound management, 2005, Volume: 51, Issue:1 Topics: Administration, Cutaneous; Amitriptyline; Anesthetics, Local; Bandages; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Pain Measurement; Patient Selection; Pressure Ulcer; Prilocaine	2005
Cyclobenzaprine for the treatment of myofascial pain in adults. The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3 Topics: Adult; Amitriptyline; Anesthetics, Local; Clonazepam; Fascia; Humans; Lidocaine; Muscle Relaxants, Central; Muscular Diseases; Pain; Randomized Controlled Trials as Topic	2009
Treating Painful Diabetic Peripheral Neuropathy: An Update. American family physician, 2016, Aug-01, Volume: 94, Issue:3 Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride	2016
Evaluation and Treatment of Vulvodynia: State of the Science. Journal of midwifery & women's health, 2023, Volume: 68, Issue:1 Topics: Amitriptyline; Female; Humans; Lidocaine; Transcutaneous Electric Nerve Stimulation; Treatment Outcome; Vulvodynia	2023

Trials

4 trial(s) available for amitriptyline and lidocaine

Article	Year
Topical amitriptyline versus lidocaine in the treatment of neuropathic pain. The Clinical journal of pain, 2008, Volume: 24, Issue:1 Topics: Administration, Topical; Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System Diseases; Prospective Studies; Sample Size; Surveys and Questionnaires; Treatment Outcome	2008
Effect of intravenous lidocaine associated with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine concentrations in fibromyalgia. The Clinical journal of pain, 2011, Volume: 27, Issue:4 Topics: Adolescent; Adult; Amitriptyline; Analgesics; Catecholamines; Dopamine; Double-Blind Method; Drug Therapy, Combination; Female; Fibromyalgia; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Norepinephrine; Pain Measurement; Prospective Studies; Serotonin; Young Adult	2011
[Intraosseous blocks in the treatment of symmetrical distal diabetic polyneuropathy]. Terapevticheskii arkhiv, 2013, Volume: 85, Issue:4 Topics: Aged; Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Diabetic Neuropathies; Female; Follow-Up Studies; Humans; Lidocaine; Lower Extremity; Male; Middle Aged; Neuralgia; Severity of Illness Index; Treatment Outcome	2013
Effect of intravenous lidocaine combined with amitriptyline on pain intensity, clinical manifestations and the concentrations of IL-1, IL-6 and IL-8 in patients with fibromyalgia: A randomized double-blind study. International journal of rheumatic diseases, 2016, Volume: 19, Issue:10 Topics: Administration, Intravenous; Adult; Amitriptyline; Anesthetics, Local; Biomarkers; Brazil; Double-Blind Method; Drug Therapy, Combination; Female; Fibromyalgia; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Lidocaine; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies; Surveys and Questionnaires; Time Factors; Treatment Outcome	2016

Other Studies

58 other study(ies) available for amitriptyline and lidocaine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity. Journal of medicinal chemistry, 1981, Volume: 24, Issue:3 Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship	1981
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
The standardisation of thin-layer chromatographic systems for the identification of basic drugs. Journal of chromatography, 1975, Jul-16, Volume: 110, Issue:2 Topics: Amitriptyline; Amphetamine; Caffeine; Chromatography, Thin Layer; Codeine; Hydrogen-Ion Concentration; Lidocaine; Meperidine; Pharmaceutical Preparations; Quinine; Silicon Dioxide; Solvents; Strychnine	1975
Hyperventilation in tricyclic antidepressant poisoning. Critical care medicine, 1979, Volume: 7, Issue:12 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Lidocaine; Physostigmine; Respiration, Artificial; Ventricular Fibrillation	1979
Cocaine-related death. Journal of forensic sciences, 1977, Volume: 22, Issue:2 Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Brain Edema; Cocaine; Ethanol; Female; Forensic Medicine; Humans; Intracranial Aneurysm; Lidocaine; Male; Morphine; Nortriptyline; Phenmetrazine; Substance-Related Disorders; Suicide; Tissue Distribution	1977
The risk of potentiating effect of local anaesthesia with adrenalin in patients treated with tricyclic antidepressants. Svensk tandlakare tidskrift. Swedish dental journal, 1975, Volume: 68, Issue:1 Topics: Adult; Aged; Amitriptyline; Anesthesia, Local; Blood Pressure; Drug Interactions; Epinephrine; Female; Humans; Imipramine; Lidocaine; Male; Membranes; Middle Aged; Nortriptyline; Pulse; Time Factors	1975
Blockade of cardiac sodium channels by amitriptyline and diphenylhydantoin. Evidence for two use-dependent binding sites. Circulation research, 1991, Volume: 69, Issue:3 Topics: Amitriptyline; Animals; Binding Sites; Binding, Competitive; Heart; In Vitro Techniques; Lidocaine; Myocardium; Phenytoin; Rabbits; Sodium; Sodium Channels	1991
Relationship between use-dependent effects of antiarrhythmic drugs on conduction and Vmax in canine cardiac Purkinje fibers. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: Action Potentials; Amitriptyline; Anesthesia, Local; Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Heart Conduction System; Kinetics; Lidocaine; Mexiletine; Microelectrodes; Procainamide; Purkinje Fibers	1987
Effect of CO2 on a brain extracellular space marker and evidence of its neuronal modulation. Brain research, 1985, Sep-02, Volume: 342, Issue:1 Topics: Amitriptyline; Animals; Brain; Carbon Dioxide; Extracellular Space; Lidocaine; Locus Coeruleus; Male; Naphthalenesulfonates; Norepinephrine; Rats; Rats, Inbred Strains	1985
[Amitriptyline poisoning with severe cardiac arrhythmia treated with lidocaine]. Ugeskrift for laeger, 1970, Jan-15, Volume: 132, Issue:3 Topics: Accidents, Home; Amitriptyline; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Infant; Injections, Intravenous; Lidocaine	1970
Management of rheumatoid arthritis. Southern medical journal, 1969, Volume: 62, Issue:3 Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health Personnel; Barbiturates; Chlordiazepoxide; Chloroquine; Exercise Therapy; Gold; Hospitalization; Hot Temperature; Humans; Indomethacin; Injections, Intra-Articular; Lidocaine; Mechlorethamine; Phenylbutazone; Physical Therapy Modalities; Physician-Patient Relations; Prednisolone; Rest	1969
Treatment of ventricular tachyarrhythmias resulting from amitriptyline toxicity in dogs. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2 Topics: Amitriptyline; Animals; Bicarbonates; Dogs; Female; Hyperventilation; Lidocaine; Male; Saline Solution, Hypertonic; Sodium Bicarbonate; Tachycardia	1984
Lidocaine and amitriptyline interaction during experimental haemoperfusion. Human toxicology, 1984, Volume: 3, Issue:3 Topics: Amitriptyline; Animals; Brain; Dogs; Drug Interactions; Female; Hemoperfusion; Kinetics; Lidocaine; Liver; Lung; Male; Myocardial Contraction; Myocardium; Nortriptyline	1984
Effects of magnesium sulfate and lidocaine in the treatment of ventricular arrhythmias in experimental amitriptyline poisoning in the rat. Critical care medicine, 1994, Volume: 22, Issue:3 Topics: Amitriptyline; Analysis of Variance; Animals; Blood Pressure; Electrocardiography; Heart Rate; Lidocaine; Magnesium Sulfate; Male; Rats; Rats, Wistar; Tachycardia, Ventricular	1994
Dysesthetic ("essential") vulvodynia. Treatment with amitriptyline. The Journal of reproductive medicine, 1993, Volume: 38, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Estrogen Replacement Therapy; Female; Follow-Up Studies; Humans; Lidocaine; Menopause; Middle Aged; Paresthesia; Retrospective Studies; Vulvar Diseases	1993
Human placental ecto-enzymes: studies on the plasma membrane anchorage and effect of inhibitors of ATP-metabolizing enzymes. Research communications in molecular pathology and pharmacology, 1997, Volume: 96, Issue:1 Topics: 5'-Nucleotidase; Alkaline Phosphatase; Amitriptyline; Apyrase; Caffeine; Cell Membrane; Endopeptidases; Enzyme Inhibitors; Female; Fluphenazine; Glycosylphosphatidylinositols; Humans; Lidocaine; Microvilli; Nucleotides; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Placenta; Type C Phospholipases	1997
The anti-allodynic effects of amitriptyline, gabapentin, and lidocaine in a rat model of neuropathic pain. Anesthesia and analgesia, 1998, Volume: 87, Issue:6 Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Infusions, Intravenous; Infusions, Parenteral; Lidocaine; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley	1998
Complex regional pain syndrome (CRPS) with resistance to local anesthetic block: a case report. Journal of clinical anesthesia, 2000, Volume: 12, Issue:1 Topics: Acetates; Amines; Amitriptyline; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Lidocaine; Nerve Block; Physical Therapy Modalities; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympathetic Nervous System	2000
Effect of drugs used for neuropathic pain management on tetrodotoxin-resistant Na(+) currents in rat sensory neurons. Anesthesiology, 2001, Volume: 94, Issue:1 Topics: Amitriptyline; Analgesics; Anesthetics, Local; Animals; Cells, Cultured; Diethylcarbamazine; Drug Interactions; Electric Stimulation; Lidocaine; Memantine; Membrane Potentials; Mexiletine; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin	2001
N-phenylethyl amitriptyline in rat sciatic nerve blockade. Anesthesiology, 2002, Volume: 96, Issue:6 Topics: Amitriptyline; Anesthetics, Local; Animals; Cells, Cultured; Lidocaine; Nerve Block; Rats; Sciatic Nerve; Time Factors	2002
The effect of local anesthetics and amitriptyline on peroxidation in vivo in an inflammatory rat model: preliminary reports. Anesthesia and analgesia, 2002, Volume: 95, Issue:4 Topics: Amides; Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Bupivacaine; Carrageenan; Inflammation; Lidocaine; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Ropivacaine; Thiobarbituric Acid Reactive Substances	2002
Cutaneous analgesia after transdermal application of amitriptyline versus lidocaine in rats. Anesthesia and analgesia, 2003, Volume: 96, Issue:6 Topics: Administration, Cutaneous; Amitriptyline; Analgesics; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Erythema; Lidocaine; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Reflex; Skin	2003
Assessment of differential blockade by amitriptyline and its N-methyl derivative in different species by different routes. Anesthesiology, 2003, Volume: 98, Issue:6 Topics: Amitriptyline; Anesthesia, Spinal; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cells, Cultured; Electrophysiology; Female; Lidocaine; Nerve Block; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sheep; Sodium Channel Blockers; Sodium Channels; Species Specificity	2003
Complex Regional Pain Syndrome type I following radial artery cardiac catheterization. International journal of cardiology, 2005, May-11, Volume: 101, Issue:1 Topics: Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Angina, Unstable; Cardiac Catheterization; Forearm; Humans; Lidocaine; Male; Middle Aged; Radial Artery; Reflex Sympathetic Dystrophy	2005
Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo. Anesthesiology, 2006, Volume: 104, Issue:6 Topics: Amitriptyline; Anesthetics, Local; Animals; Apoptosis; Cells, Cultured; Enzyme Inhibitors; Female; Ganglia, Spinal; Imidazoles; Lidocaine; Membrane Potentials; Mitochondria; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Sciatic Nerve	2006
Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1 Topics: Amitriptyline; Animals; Cell Line; Dose-Response Relationship, Drug; Lidocaine; Mice; Mice, Inbred C57BL; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Protein Subunits; Rats; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin	2007
Treatment of tricyclic antidepressant cardiac toxicity. Pediatric emergency care, 2008, Volume: 24, Issue:3 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child, Preschool; Humans; Hydrogen-Ion Concentration; Lidocaine; Magnesium Sulfate; Male; Sodium Bicarbonate; Tachycardia, Ventricular; Treatment Outcome; Turkey	2008
Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2012, Volume: 20, Issue:7 Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Anesthetics, Local; Cohort Studies; Drug Combinations; Female; Gels; Humans; Ketamine; Lidocaine; Male; Medication Adherence; Middle Aged; Neoplasms; Neuralgia; Pain Measurement; Pilot Projects; Prospective Studies; Radiodermatitis	2012
New index of pain triggered by spinal activation of voltage-dependent sodium channels. Journal of anesthesia, 2013, Volume: 27, Issue:6 Topics: Amitriptyline; Animals; gamma-Aminobutyric Acid; Injections, Spinal; Lidocaine; Male; Mexiletine; Mice; Mice, Inbred ICR; Morphine; Nociceptive Pain; Pain Management; Pain Measurement; Pregabalin; Spine; Voltage-Gated Sodium Channel Agonists; Voltage-Gated Sodium Channels	2013
[Shingles symptoms are gone but not the pain]. MMW Fortschritte der Medizin, 2015, Jul-23, Volume: 157, Issue:13 Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Ibuprofen; Lidocaine; Neuralgia, Postherpetic; Phenols; Pregabalin; Tapentadol; Treatment Failure	2015
[The principles of pharmacotherapy of poststroke shoulder pain]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:5 Topics: Amines; Amitriptyline; Anti-Inflammatory Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Pregabalin; Shoulder Pain; Stroke	2015
IonWorks Barracuda Assay for Assessment of State-Dependent Sodium Channel Modulators. Assay and drug development technologies, 2016, Volume: 14, Issue:2 Topics: Amitriptyline; Animals; Cells, Cultured; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; HEK293 Cells; High-Throughput Screening Assays; Humans; Lidocaine; NAV1.7 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship; Tetracaine	2016
Determination of Degradation Products of Cyclobenzaprine Hydrochloride, Lidocaine and Piroxicam in a Semi-Topical Formulation: MS-MS Confirmation of Unknown Impurities. Journal of chromatographic science, 2016, Volume: 54, Issue:6 Topics: Amitriptyline; Lidocaine; Piroxicam; Tandem Mass Spectrometry	2016
Amitriptyline Activates TrkA to Aid Neuronal Growth and Attenuate Anesthesia-Induced Neurodegeneration in Rat Dorsal Root Ganglion Neurons. Medicine, 2016, Volume: 95, Issue:18 Topics: Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Lidocaine; Nerve Degeneration; Rats; Real-Time Polymerase Chain Reaction; Receptor, trkA; Receptor, trkB	2016
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability. Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4 Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lidocaine; Male; Mianserin; Mirtazapine; Pain Measurement; Pruritus; Retrospective Studies	2017
Successful Treatment of Epidermal Nevus-associated Pruritus with Topical Ketamine-Amitriptyline-Lidocaine. Acta dermato-venereologica, 2018, 01-12, Volume: 98, Issue:1 Topics: Administration, Cutaneous; Amitriptyline; Analgesics; Antipruritics; Drug Combinations; Forehead; Humans; Ketamine; Lidocaine; Male; Nevus; Pruritus; Skin Neoplasms; Young Adult	2018
Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding. Journal of veterinary pharmacology and therapeutics, 2021, Volume: 44, Issue:1 Topics: Amitriptyline; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Blood Proteins; Dogs; Gene Expression Regulation; Genotype; HIV Protease Inhibitors; Indinavir; Lidocaine; Orosomucoid; Polymorphism, Genetic; Protein Binding; Verapamil	2021
Amitriptyline Protects Against Lidocaine-induced Neurotoxicity in SH-SY5Y Cells via Inhibition of BDNF-mediated Autophagy. Neurotoxicity research, 2021, Volume: 39, Issue:2 Topics: Amitriptyline; Apoptosis; Autophagy; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cell Survival; Humans; Lidocaine; Neuroprotective Agents	2021
Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion. Investigative ophthalmology & visual science, 2021, 01-04, Volume: 62, Issue:1 Topics: Amitriptyline; Animals; Carbamazepine; Carbon Dioxide; Cornea; Corneal Stroma; Electrophysiology; Female; Guinea Pigs; Lidocaine; Male; Nerve Fibers; Nerve Regeneration; Nociceptors; Ophthalmic Nerve; Sodium Channel Blockers; Surgical Flaps	2021
Postinjury treatments to make early tactical aeromedical evacuation practical for the brain after TBI. The journal of trauma and acute care surgery, 2021, 08-01, Volume: 91, Issue:2S Suppl 2 Topics: Adenosine; Air Ambulances; Allopurinol; Amitriptyline; Animals; Brain; Brain Chemistry; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Emergency Medical Services; Lidocaine; Magnesium; Male; Mice; Mice, Inbred C57BL; Propranolol; Rotarod Performance Test	2021
Antidepressants Are Poor Inhibitors of Heat-Evoked Ion Currents Mediated by TRPM2. Pharmacology, 2022, Volume: 107, Issue:9-10 Topics: Adenosine Diphosphate Ribose; Amitriptyline; Animals; Antidepressive Agents; Citalopram; Duloxetine Hydrochloride; Fluoxetine; HEK293 Cells; Hot Temperature; Humans; Ketamine; Lidocaine; Mice; Paroxetine; Pregabalin; Sertraline; TRPM Cation Channels	2022