amitriptyline and lamotrigine

amitriptyline has been researched along with lamotrigine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.70)18.2507
2000's12 (44.44)29.6817
2010's13 (48.15)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goodwin, FK1
Gustorff, B; Kress, HG; Nahlik, G; Spacek, A1
Chan, W; Yen, HL1
Hong, HB; Xu, RJ1
Cantú, MD; Carrilho, E; Lacerda, CA; Lanças, FM; Queiroz, ME; Toso, DR1
Bhansali, A; Hota, D; Jose, VM; Pandhi, P1
van Doorn, PA1
Davenport, R; Patel, HN; Patel, NC; Roberts, CK1
Cuadrado, ML; Fernández, R; García-Ramos, R; Gómez-Vicente, L; Guerrero, AL; Herrero, S; Peñas, ML; Porta-Etessam, J1
Oechsler, S; Skopp, G1
Clouse, AK; Eisennagel, SH; Jugus, MJ; Laping, NJ; Thorneloe, KS; Westfall, TD1
Bicknell, LT; Sanches, M; Schatte, DJ1
Eren Cevik, S; Guneysel, O; Tasyurek, T1
Agarwal, N; Joshi, M1
Chen, KY; Li, RY1

Reviews

6 review(s) available for amitriptyline and lamotrigine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Anticonvulsant therapy and suicide risk in affective disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2

    Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid

1999
[Progress on painful diabetic peripheral neuropathy treated by integrative medicine].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2005, Volume: 25, Issue:4

    Topics: Amines; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Drugs, Chinese Herbal; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Pain; Pain Measurement; Phytotherapy; Triazines

2005
[Guideline on polyneuropathy].
    Nederlands tijdschrift voor geneeskunde, 2007, Jul-14, Volume: 151, Issue:28

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Carbamazepine; Chronic Disease; Diabetes Complications; Electromyography; Humans; Lamotrigine; Neural Conduction; Neurologic Examination; Polyneuropathies; Practice Guidelines as Topic; Treatment Outcome; Triazines

2007
Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Fluoxetine; Gabapentin; Humans; Lamotrigine; Multicenter Studies as Topic; Network Meta-Analysis; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Vitamins

2022

Trials

3 trial(s) available for amitriptyline and lamotrigine

ArticleYear
Anticonvulsant therapy and suicide risk in affective disorders.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 2

    Topics: Amitriptyline; Anticonvulsants; Bipolar Disorder; Carbamazepine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lamotrigine; Lithium; Male; Mood Disorders; Prospective Studies; Risk Factors; Suicide; Suicide Prevention; Triazines; Valproic Acid

1999
Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy.
    Diabetic medicine : a journal of the British Diabetic Association, 2007, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Algorithms; Amitriptyline; Analgesics, Non-Narcotic; Calcium Channel Blockers; Cross-Over Studies; Diabetic Neuropathies; Double-Blind Method; Female; Humans; Lamotrigine; Male; Middle Aged; Pain Measurement; Placebos; Triazines

2007
Effectiveness of amitriptyline and lamotrigine in traumatic spinal cord injury-induced neuropathic pain: a randomized longitudinal comparative study.
    Spinal cord, 2017, Volume: 55, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; India; Lamotrigine; Longitudinal Studies; Male; Neuralgia; Pain Measurement; Spinal Cord Injuries; Treatment Outcome; Triazines; Young Adult

2017

Other Studies

19 other study(ies) available for amitriptyline and lamotrigine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Gabapentin in the treatment of chronic intractable pain].
    Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1

    Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Pain, Intractable; Placebos; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Time Factors; Triazines

2002
An East-West approach to the management of central post-stroke pain.
    Cerebrovascular diseases (Basel, Switzerland), 2003, Volume: 16, Issue:1

    Topics: Acetates; Acupuncture; Aged; Amines; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Pain; Pain Management; Physical Therapy Modalities; Stroke; Tramadol; Triazines

2003
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
    Analytical and bioanalytical chemistry, 2006, Volume: 386, Issue:2

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines

2006
Hallucinations during lamotrigine treatment.
    The Nurse practitioner, 2008, Volume: 33, Issue:3

    Topics: Adolescent; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Erythema Infectiosum; Female; Hallucinations; Humans; Lamotrigine; Triazines; Valproic Acid

2008
Epicrania fugax: ten new cases and therapeutic results.
    Headache, 2010, Volume: 50, Issue:3

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Lamotrigine; Male; Middle Aged; Nerve Block; Pain Measurement; Treatment Outcome; Triazines; Young Adult

2010
An in vitro approach to estimate putative inhibition of buprenorphine and norbuprenorphine glucuronidation.
    International journal of legal medicine, 2010, Volume: 124, Issue:3

    Topics: Amitriptyline; Buprenorphine; Central Nervous System Agents; Chromatography, Liquid; Glucuronosyltransferase; Humans; In Vitro Techniques; Lamotrigine; Liver; Mass Spectrometry; Microsomes, Liver; Narcotics; Nortriptyline; Oxazepam; Temazepam; Triazines

2010
Voltage-gated Na+ channel blockers reduce functional bladder capacity in the conscious spontaneously hypertensive rat.
    Urology, 2012, Volume: 79, Issue:6

    Topics: Amitriptyline; Animals; Carbamazepine; Female; Lamotrigine; Mexiletine; Rats; Rats, Inbred SHR; Receptors, Muscarinic; Sodium Channel Blockers; Sodium Channels; Triazines; Urinary Bladder, Overactive; Urodynamics

2012
Erythema multiforme vs. DRESS syndrome associated with the combined use of lamotrigine and cyclobenzaprine: a case report.
    International journal of psychiatry in medicine, 2012, Volume: 44, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antimanic Agents; Citalopram; Diagnosis, Differential; Drug Interactions; Drug Therapy, Combination; Eosinophilia; Erythema Multiforme; Female; Humans; Lamotrigine; Middle Aged; Off-Label Use; Selective Serotonin Reuptake Inhibitors; Syndrome; Triazines

2012
Intralipid emulsion treatment as an antidote in lipophilic drug intoxications.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Alprazolam; Amitriptyline; Antidotes; Blood Pressure; Dibenzothiazepines; Drug Overdose; Fat Emulsions, Intravenous; Female; Fluoxetine; Glasgow Coma Scale; Heart Rate; Humans; Lamotrigine; Lipid Metabolism; Male; Metoprolol; Middle Aged; Nifedipine; Quetiapine Fumarate; Triazines; Young Adult

2014