amitriptyline has been researched along with idazoxan in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Deighton, NM; Hamilton, CA; Reid, JL; Yakubu, MA | 1 |
| Barr, SM; Hamilton, CA; Reid, JL | 1 |
| Goodwin, WB; Guyenet, PG; Huangfu, D | 1 |
7 other study(ies) available for amitriptyline and idazoxan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Differences in the regulation of [3H]idazoxan and [3H]yohimbine binding sites in the rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amitriptyline; Animals; Binding Sites; Brain Chemistry; Dioxanes; Dioxins; Hindlimb; Idazoxan; In Vitro Techniques; Kidney; Kinetics; Norepinephrine; Rabbits; Yohimbine | 1990 |
Long-term amitriptyline treatment alters the affinity state of alpha 2 adrenoceptors in rabbit hindbrain.
Topics: Amitriptyline; Animals; Blood Pressure; Body Weight; Brain Stem; Cerebellum; Clonidine; Dioxanes; Epinephrine; Heart Rate; Idazoxan; Male; Rabbits; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors | 1995 |