amitriptyline has been researched along with dothiepin hydrochloride in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (53.85) | 18.7374 |
| 1990's | 11 (28.21) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolden-Watson, C; Cusack, B; Richelson, E; Stanton, T | 1 |
| Hyttel, J; Sánchez, C | 1 |
| Delaunay, J; Meynard, J | 1 |
| Benesová, O; Horák, J; Jelínek, R; Soucek, K | 1 |
| Cryer, PC; Rees, JA | 1 |
| Rack, PH; Vaddadi, K | 1 |
| Cowen, PJ; Gregory, CA; Sharpley, AL; Solomon, RA | 1 |
| Baldwin, D; Green, M; Montgomery, SA | 1 |
| Ishikawa, K; Kogure, M; Kubo, T; Matsumoto, A; Shibanoki, S; Watabe, S | 1 |
| Blacker, R; Chapman, N; Davey, A; Shanks, NJ | 1 |
| Hindmarch, I | 1 |
| Arie, T; Grundy, E; Waite, J | 1 |
| Dorman, T | 2 |
| Nĕmec, J | 1 |
| Balashova, MG; Lobova, EK; Smulevich, AB; Vorob'ev, VIu; Zavidovskaia, GI | 1 |
| Claghorn, JL; Goldstein, BJ; Schroeder, J | 1 |
| Stratas, NE | 1 |
| Hazama, H; Honma, H; Kawahara, K; Kishimoto, A; Mizukawa, R; Ogura, C | 1 |
| Hazama, H; Honma, H; Kawahara, K; Kishimoto, A; Kunimoto, N; Mizukawa, R; Ogura, C; Ryoke, K; Takeda, A | 1 |
| Linkowski, P; Mendlewicz, J; Rees, JA | 1 |
| Dahl, LE; Dencker, SJ; Lundin, L | 1 |
| Khan, AU | 1 |
| Sharma, SD | 1 |
| Alexander, CA; Henry, JA; Sener, EK | 1 |
| Drummer, OH; King, CV; McIntyre, IM; Skafidis, S | 1 |
| Hunter, KD; Wilson, WS | 1 |
| Langford, AM; Pounder, DJ; Taylor, KK | 1 |
| Gray, AM; Sewell, RD; Spencer, PS | 1 |
| Hamplová, J; Horácek, BM; Kittnar, O; Paclt, I; Slavícek, J; Trefný, Z | 1 |
| Ellison, Z; Evans, CL; Fombonne, E; Ha, Y; Saisch, S | 1 |
| Gray, AM; Pache, DM; Sewell, RD | 1 |
| Casarotto, MG; Craik, DJ | 1 |
| Jick, H; Jick, SS; Kaye, JA | 1 |
| Barbui, C | 1 |
| Goldney, RD | 1 |
| Bergen, H; Cooper, J; Hawton, K; Kapur, N; Murphy, E; Stalker, C; Waters, K | 1 |
| Abdelmageed, OH; Attia, TZ; Derayea, SM; Erikawa, Y; Horii, C; Koizumi, A; Komiyama, Y; Miyamoto, M; Node, J; Omar, MA; Uno, T; Yamada, M; Yamashita, T; Yasuhara, Y | 1 |
| Abdelmageed, OH; Attia, TZ; Derayea, SM; Hammad, MA; Hayasaki, A; Kagawa, Y; Miyamoto, M; Nakamura, T; Omar, MA; Sato, T; Tsujino, H; Uno, T; Yamashita, T; Yasuhara, Y | 1 |
1 review(s) available for amitriptyline and dothiepin hydrochloride
| Article | Year |
|---|---|
Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding, Competitive; Biogenic Amines; Depression; Humans; Receptors, Catecholamine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors | 1999 |
13 trial(s) available for amitriptyline and dothiepin hydrochloride
| Article | Year |
|---|---|
[Clinical and comparative trial of dosulepin and amitriptyline].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Depression; Depressive Disorder, Major; Dibenzothiepins; Dothiepin; Drug Tolerance; Female; Humans; Male; Middle Aged; Motor Activity; Sleep Wake Disorders; Thymus Gland | 1978 |
A single-blind comparative study of once daily dothiepin ("Prothiaden") and divided daily doses of amitriptyline.
Topics: Adult; Amitriptyline; Depression; Dibenzothiepins; Dothiepin; Female; Humans; Male; Middle Aged | 1976 |
Side effects of tricyclic antidepressand drugs with particular reference fo dothiepin.
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Female; Humans; Male; Middle Aged | 1975 |
Slow wave sleep and 5-HT2 receptor sensitivity during maintenance tricyclic antidepressant treatment.
Topics: Adult; Aged; Amitriptyline; Brain; Cyproheptadine; Depressive Disorder; Dothiepin; Double-Blind Method; Electroencephalography; Female; Humans; Male; Middle Aged; Reaction Time; Receptors, Serotonin; Sleep Stages; Sleep, REM | 1990 |
The drug treatment of depression in general practice: a comparison of nocte administration of trazodone with mianserin, dothiepin and amitriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Dothiepin; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Humans; Male; Mianserin; Middle Aged; Random Allocation; Sleep; Trazodone | 1988 |
A controlled trial of antidepressant medication in elderly in-patients.
Topics: Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dibenzothiepins; Dothiepin; Double-Blind Method; Female; Humans; Inpatients; Longitudinal Studies; Male; Mianserin; Random Allocation | 1986 |
Toxicity of tricyclic antidepressants: are there important differences?
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cardiovascular System; Clinical Trials as Topic; Dothiepin; Humans; Imipramine; Lofepramine; Rats; Suicide; United Kingdom | 1985 |
Comparison of the electrocardiographic effect of dothiepin and amitriptyline.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dibenzothiepins; Dothiepin; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Placebos | 1984 |
A double-blind study of the efficacy and safety of dothiepin hydrochloride in the treatment of major depressive disorder.
Topics: Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Dibenzothiepins; Dothiepin; Double-Blind Method; Humans; Placebos; Psychiatric Status Rating Scales; Sleep Stages; Vision Disorders; Xerostomia | 1984 |
A double-blind comparison of dothiepin and amitriptyline in patients with primary affective disorder: serum levels and clinical response.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Double-Blind Method; Female; Humans; Male; Middle Aged; Nortriptyline | 1980 |
Clinical trial comparison of a sustained release form of amitriptyline with dothiepin.
Topics: Adolescent; Adult; Amitriptyline; Body Weight; Clinical Trials as Topic; Delayed-Action Preparations; Depression; Dibenzothiepins; Dothiepin; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged | 1980 |
A double-blind study of dothiepin hydrochloride (Prothiaden) and amitriptyline in out-patients with masked depression.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Double-Blind Method; Female; Humans; Male; Middle Aged; Outpatients; Somatoform Disorders | 1981 |
A comparison of the therapeutic and cardiovascular effects of a single nightly dose of Prothiaden (dothiepin, dosulepin) and Lentizol (sustained-release amitriptyline) in depressed elderly patients.
Topics: Aged; Amitriptyline; Cardiovascular System; Delayed-Action Preparations; Depression; Dibenzothiepins; Dothiepin; Drug Administration Schedule; Female; Humans; Male | 1981 |
25 other study(ies) available for amitriptyline and dothiepin hydrochloride
| Article | Year |
|---|---|
Antagonism of the five cloned human muscarinic cholinergic receptors expressed in CHO-K1 cells by antidepressants and antihistaminics.
Topics: Animals; Antidepressive Agents; CHO Cells; Cricetinae; Cricetulus; Histamine H1 Antagonists; Humans; Muscarinic Antagonists | 1993 |
Cardiotoxicity of tricyclic antidepressants and maprotiline in the chick embryo. A comparative study.
Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Chick Embryo; Dothiepin; Heart Arrest; Imipramine; Lethal Dose 50; Maprotiline; Myocardial Contraction | 1978 |
Why do amitriptyline and dothiepin appear to be so dangerous in overdose?
Topics: Amitriptyline; Cross-Sectional Studies; Dibenzothiepins; Dose-Response Relationship, Drug; Dothiepin; Drug Overdose; Humans; Incidence; Risk Factors; Suicide; United Kingdom | 1989 |
Effects of various tricyclic antidepressants on amine uptake.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biogenic Amines; Dopamine; Dothiepin; Fenclonine; Imipramine; Methyltyrosines; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin | 1986 |
A pharmacological profile of fluoxetine and other antidepressants on aspects of skilled performance and car handling ability.
Topics: Adult; Amitriptyline; Automobile Driving; Dothiepin; Female; Flicker Fusion; Fluoxetine; Humans; Psychomotor Performance; Reaction Time | 1988 |
Cardiotoxic effects of tricyclic antidepressants imipramine, amitriptiline and dosulepin (prothiaden spofa) in an acute experiment in rats.
Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Dibenzothiepins; Dothiepin; Heart; Imipramine; Rats | 1974 |
[Problems of differentiated thymoleptic therapy in phasic depressions].
Topics: Adolescent; Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Azocines; Benzoates; Benzofurans; Bipolar Disorder; Clomipramine; Cyclothymic Disorder; Depression; Dibenzazepines; Dimethylamines; Dothiepin; Humans; Imipramine; Methylamines; Middle Aged; Personality Disorders; Propylamines; Schizophrenia | 1974 |
Age differences in effects on blood pressure, flicker fusion frequency, salivation and pharmacokinetics of single oral doses of dothiepin and amitriptyline.
Topics: Adult; Aged; Aging; Amitriptyline; Blood Pressure; Dibenzothiepins; Dothiepin; Flicker Fusion; Humans; Kinetics; Male; Salivation | 1983 |
Influence of single doses of dothiepin and amitriptyline on physiological measures and psychomotor performance in normal young and elderly volunteers.
Topics: Adult; Aged; Amitriptyline; Arousal; Attention; Blood Pressure; Dibenzothiepins; Dothiepin; Double-Blind Method; Flicker Fusion; Heart Rate; Humans; Psychomotor Performance; Salivation | 1983 |
A double-blind comparison of dothiepin and amitriptyline in the treatment of depression with anxiety.
Topics: Adult; Amitriptyline; Anxiety; Depression; Dibenzothiepins; Dothiepin; Double-Blind Method; Female; Humans; Male; Middle Aged | 1981 |
Relative mortality from overdose of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Dothiepin; Drug Overdose; England; Humans; Monoamine Oxidase Inhibitors; Retrospective Studies; Scotland; Selective Serotonin Reuptake Inhibitors; Wales | 1995 |
Dual ultraviolet wavelength high-performance liquid chromatographic method for the forensic or clinical analysis of seventeen antidepressants and some selected metabolites.
Topics: Amitriptyline; Antidepressive Agents; Chromatography, High Pressure Liquid; Dothiepin; Doxepin; Forensic Medicine; Humans; Microchemistry; Nortriptyline; Postmortem Changes; Quality Control | 1993 |
The effects of antidepressant drugs on salivary flow and content of sodium and potassium ions in human parotid saliva.
Topics: Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Dothiepin; Female; Fluoxetine; Humans; Male; Middle Aged; Muscarinic Antagonists; Parotid Gland; Paroxetine; Potassium; Prospective Studies; Receptors, Muscarinic; Retrospective Studies; Saliva; Secretory Rate; Selective Serotonin Reuptake Inhibitors; Sodium; Xerostomia | 1995 |
Drug concentration in selected skeletal muscles.
Topics: Acetaminophen; Adult; Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Cadaver; Central Nervous System Agents; Chromatography, High Pressure Liquid; Diaphragm; Dothiepin; Drug Overdose; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Muscle, Skeletal; Suicide; Temazepam; Time Factors; Tissue Distribution; Toxicology | 1998 |
The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds.
Topics: Abdominal Muscles; Acetic Acid; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Male; Maprotiline; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Neurotransmitter Uptake Inhibitors; Opioid Peptides; Pain Measurement; Paroxetine; Protease Inhibitors; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Thiorphan | 1998 |
Antidepressant drugs and heart electrical field.
Topics: Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cardiovascular Diseases; Citalopram; Dothiepin; Electrocardiography; Electrophysiology; Female; Heart; Heart Rate; Humans; Lithium; Male; Mental Disorders; Middle Aged; Muscarinic Antagonists; Selective Serotonin Reuptake Inhibitors; Tachycardia | 1998 |
Tricyclic antidepressants in adolescent depression. A case report.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Child; Depressive Disorder; Dothiepin; Drug Monitoring; Drug Therapy, Combination; Electrocardiography; Humans; Lithium Carbonate; Lofepramine; Male; Paroxetine; Trazodone | 1998 |
Do alpha2-adrenoceptors play an integral role in the antinociceptive mechanism of action of antidepressant compounds?
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Drug Interactions; Male; Maprotiline; Mice; Norepinephrine; Pain Measurement; Paroxetine; Random Allocation; Receptors, Adrenergic; Selective Serotonin Reuptake Inhibitors | 1999 |
Ring flexibility within tricyclic antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Carbon Radioisotopes; Dothiepin; Doxepin; Imipramine; Magnetic Resonance Spectroscopy; Molecular Conformation; Pliability; Temperature | 2001 |
Antidepressants and the risk of suicidal behaviors.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Amitriptyline; Antidepressive Agents; Case-Control Studies; Child; Dothiepin; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Risk; Selective Serotonin Reuptake Inhibitors; Suicide; Suicide, Attempted; United Kingdom | 2004 |
Antidepressants and the risk of suicidal behaviors.
Topics: Amitriptyline; Antidepressive Agents; Dothiepin; Fluoxetine; Humans; Paroxetine; Risk; Selective Serotonin Reuptake Inhibitors; Suicide | 2004 |
Antidepressants and suicide: a commentary on a significant contribution to this debate.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Depression; Dothiepin; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Risk Factors; Selective Serotonin Reuptake Inhibitors; Suicide; Suicide, Attempted; Time Factors; United Kingdom | 2005 |
A comparative study of non-fatal self-poisoning with antidepressants relative to prescribing in three centres in England.
Topics: Amitriptyline; Antidepressive Agents; Cross-Sectional Studies; Cyclohexanols; Dothiepin; England; Guideline Adherence; Humans; Odds Ratio; Poisoning; Practice Patterns, Physicians'; Recurrence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride | 2010 |
Comparison of cytochrome p450 mediated metabolism of three central nervous system acting drugs.
Topics: Amitriptyline; Central Nervous System Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dothiepin; Fluphenazine; Humans; Kinetics; Molecular Structure; Recombinant Proteins | 2012 |
Effect of cytochrome P450 2C19 and 2C9 amino acid residues 72 and 241 on metabolism of tricyclic antidepressant drugs.
Topics: Amino Acid Sequence; Amitriptyline; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Dothiepin; Humans; Imipramine; Molecular Sequence Data; Point Mutation; Protein Binding; Substrate Specificity | 2014 |