amitriptyline and dextromethorphan

amitriptyline has been researched along with dextromethorphan in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baettig, D; Baumann, P; Breyer-Pfaff, U; Jonzier-Perey, M; Monney, C; Nill, K; Nusser, E; Pfandl, B1
Amey, M; Baettig, D; Baumann, P; Bryois, C; Jonzier-Perey, M; Koeb, L; Meyer, JW; Monney, C; Woggon, B1
Reid, A; Sawynok, J1
Frank, JG; Keller, A; Nuwayhid, SJ; Werling, LL1
Forget, P; Gala, JL; le Polain de Waroux, B; Wallemacq, P1

Reviews

1 review(s) available for amitriptyline and dextromethorphan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for amitriptyline and dextromethorphan

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Enantioselective amitriptyline metabolism in patients phenotyped for two cytochrome P450 isozymes.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:4

    Topics: Adult; Amitriptyline; Cytochrome P-450 Enzyme System; Dextromethorphan; Female; Humans; Isoenzymes; Male; Mephenytoin; Metabolic Clearance Rate; Middle Aged; Nortriptyline; Phenotype; Regression Analysis; Stereoisomerism

1992
Dextromethorphan and mephenytoin phenotyping of patients treated with thioridazine or amitriptyline.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:1

    Topics: Adult; Amitriptyline; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Dextromethorphan; Female; Humans; Liver; Male; Mephenytoin; Middle Aged; Mixed Function Oxygenases; Phenotype; Thioridazine

1992
Peripheral interactions between dextromethorphan, ketamine and amitriptyline on formalin-evoked behaviors and paw edema in rats.
    Pain, 2003, Volume: 102, Issue:1-2

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Dextromethorphan; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Edema; Excitatory Amino Acid Antagonists; Formaldehyde; Hindlimb; Histamine; Injections, Subcutaneous; Ketamine; Male; p-Methoxy-N-methylphenethylamine; Pain; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Time Factors

2003
A comparison of the binding profiles of dextromethorphan, memantine, fluoxetine and amitriptyline: treatment of involuntary emotional expression disorder.
    Experimental neurology, 2007, Volume: 207, Issue:2

    Topics: Affective Symptoms; Amitriptyline; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Brain; Dextromethorphan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoxetine; Male; Memantine; Membranes; Radioligand Assay; Rats; Receptors, Neurotransmitter

2007
Life-threatening dextromethorphan intoxication associated with interaction with amitriptyline in a poor CYP2D6 metabolizer: a single case re-exposure study.
    Journal of pain and symptom management, 2008, Volume: 36, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antitussive Agents; Coma; Cytochrome P-450 CYP2D6; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Genetic Predisposition to Disease; Humans; Male; Middle Aged

2008