amitriptyline has been researched along with desipramine in 494 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 359 (72.67) | 18.7374 |
| 1990's | 59 (11.94) | 18.2507 |
| 2000's | 40 (8.10) | 29.6817 |
| 2010's | 28 (5.67) | 24.3611 |
| 2020's | 8 (1.62) | 2.80 |
| Authors | Studies |
|---|---|
| Crichlow, CA; Geyer, HM; Klioze, SS; Kruse, H; Martin, LL; Worm, M | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM | 1 |
| Marx, M; Wallach, MB; Weinhardt, K | 1 |
| Ross, BS; Wiley, RA | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Fortunato, JM; Geyer, HM; Glamkowski, EJ | 1 |
| Chiang, GH; Unger, SH | 1 |
| Burghard, H; Ellis, DB; Fortunato, J; Geyer, HM; Glamkowski, EJ; Ong, HH; Profitt, JA; Wilker, JC | 1 |
| Anderson, VB; Geyer, HM; Kruse, H; Ong, HH; Profitt, JA; Wilker, JC | 1 |
| Crichlow, CA; Dekow, FW; Ellis, DB; Geyer, HM; Kruse, H; Martin, LL; Setescak, LL; Worm, M | 1 |
| Agnew, MN; Geyer, HM; Kruse, H; Martin, LL; Wilker, JC; Worm, M | 1 |
| Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD | 1 |
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Keserü, GM | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Kenny, PW; Toulmin, A; Wood, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gao, ZB; Gunosewoyo, H; Liu, T; Pang, T; Shi, JJ; Shi, M; Sun, H; Tang, J; Xu, YZ; Yang, F; Yu, LF; Zhang, W; Zheng, YM | 1 |
| Bibak, N; Blaess, M; Bonaterra, GA; Claus, RA; Deigner, HP; Kinscherf, R; Kohl, M; Laufer, S | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Hruby, VJ; Lee, YS; Munawar, MA; Porreca, F; Rankin, D | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Modestin, J; Petrin, A | 1 |
| Mason, MF | 1 |
| Adolphe, AB; Dorsey, ER; Napoliello, MJ | 1 |
| Maas, JW | 2 |
| Hollister, LE | 2 |
| Richelson, E | 1 |
| Fromm, GH; Glass, JD | 1 |
| Levine, RM; Maickel, RP; Spaulding, JH; Zabik, JE | 1 |
| Hollander, CS; Tai, HH | 1 |
| Franz, DN; Sangdee, C | 1 |
| Bickel, MH | 2 |
| Nielsen, M | 1 |
| Nayler, WG; Petch, MC | 1 |
| Burgess, CD; Turner, P; Wadsworth, J | 1 |
| Amin, MM; Cooper, R; Khalid, R; Lehmann, HE | 1 |
| Dorrity, F; Jobson, K; Linnoila, M | 1 |
| Bielski, RJ; Bloom, V; Friedel, RO; Veith, RC | 1 |
| Briley, M; Langer, SZ; Raisman, R | 1 |
| Bradley, PB; Neal, H | 1 |
| Albert, W; Klicpera, C; Strian, F | 1 |
| Orsulak, PJ; Schildkraut, JJ | 1 |
| Biggs, JT; Petit, JM; Spiker, DG; Ziegler, VE | 1 |
| Braestrup, C; Nielsen, M | 1 |
| Adams, RF; Schmidt, GJ; Vandemark, FL | 1 |
| Adolphe, A; Blackwell, B; Enders, P; Kuzma, R; Stefopoulos, A | 1 |
| Davis, CM; Fenimore, DC; Meyer, CJ | 1 |
| Bailey, DN; Jatlow, PI; Langou, RA; Van Dyke, C | 1 |
| Lohmann, HJ; Miles, DG; Proelss, HF | 1 |
| Helmeste, DM; Stancer, HC; Tang, SW | 1 |
| Biggs, JT; Petit, JM | 1 |
| Cooper, TB; Friedman, MJ; Green, R; Ives, JO; Nies, A; Ravaris, CL; Robinson, DS | 1 |
| Ghosh, PK; Hrdina, PD | 1 |
| Davis, CM; Fenimore, DC; Hsu, F; Meyer, CJ; Zlatkis, A | 1 |
| Breyer, U; Villumsen, K | 1 |
| Lippman, W; Pugsley, TA | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| Eplov, L; Nielsen, M; Scheel-Krüger, J | 1 |
| Henry, BW; Overall, JE; Woodward, JA | 1 |
| Huang, CL; Liu, SJ; Waters, IW | 1 |
| Krupp, P; Wesp, M | 1 |
| Renyi, AL; Ross, SB | 4 |
| Oksenkrug, GF | 1 |
| Bobkiewicz, T; Chodera, A; Drutel, B; Szpunar, K | 1 |
| Cai, Z; McCaslin, PP | 1 |
| de Zwaan, M | 1 |
| Bal, AK; Bird, MM | 1 |
| Dubner, R; Lynch, SA; Max, MB; Muir, J; Shoaf, SE; Smoller, B | 1 |
| Barnes, JM; Barnes, NM; Champaneria, S; Costall, B; Hornsby, CD; Naylor, RJ | 1 |
| Fast, GA; Preskorn, SH | 1 |
| Field, SL; Murray, M | 1 |
| Bowery, NG; Johnson, AM; Nelson, DR; Palmer, KJ; Pratt, GD | 1 |
| Doogan, DP | 1 |
| Czuczwar, SJ; Gustaw, J; Kleinrok, Z | 1 |
| Graf, U; van Schaik, N | 1 |
| Fujimoto, K; Ookuma, K; Sakata, T | 1 |
| Bienenfeld, D; Burk, J; Geier, P; Kay, J; Marvel, NT; Nadolny, G; Slomowitz, M; Zimmer, L | 1 |
| Brøsen, K; Gram, LF; Kragh-Sørensen, P | 1 |
| Hersh, EV; Kaplan, P | 1 |
| Giordano, J; Rogers, LW | 1 |
| Mizukami, Y; Yasuda, K | 1 |
| Bal-Klara, A; Bird, MM | 1 |
| Kitteringham, NR; Park, BK; Riley, RJ; Roberts, P | 1 |
| Lavoie, PA; Tiberi, M | 2 |
| Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI | 1 |
| Carbary, TJ; Commissaris, RL; Fontana, DJ | 1 |
| Anisman, H; Shanks, N | 1 |
| Buckett, WR; Butler, SA; Heal, DJ; Hurst, EM | 1 |
| Jackson, RD; Mysiw, WJ | 1 |
| Debus, JR; Feldman-Koffler, F; Giles, DE; Jarrett, RB; Orsulak, PJ; Roffwarg, HP; Rush, AJ; Weissenburger, J | 1 |
| Carlson, HE; Spar, JE; Wilkins, JN | 1 |
| Cavicchia, S; Dewey, DA; DiJohnson, C; Kimes, I; Kramer, MS; Little, P; Schmidt, R; Sheves, P; Vogel, WH | 1 |
| Davidson, JR; Erickson, L; Kudler, HS; Stein, R | 1 |
| Richens, A; Tedstone, JE; Tsanaclis, LM; Williams, J; Wilson, JF | 1 |
| Danti, S; Fermanian, J; Frances, H | 1 |
| Burton, ME; Kenney, JT; Kolodner, RM; Orsulak, PJ | 1 |
| Cooper, MM; Day, JS; Sethy, VH | 1 |
| Cools, AR | 1 |
| Coble, PA; Kupfer, DJ; Perel, JM; Pollock, B; Shipley, JA; Spiker, DG | 1 |
| Archer, T; Danysz, W; Hiltunen, AJ; Järbe, TU; Kostowski, W; Malatynska, E; Plaznik, A | 1 |
| Fernstrom, MH; Kupfer, DJ | 1 |
| Halliday, CA; Wise, H | 1 |
| Frangakis, MV; Kimelberg, HK | 1 |
| Czyrak, A; Klimek, V; Mogilnicka, E; Nowak, G | 1 |
| Chalton, DO; de Villiers, AS; Lamm, MC; Russell, VA; Taljaard, JJ | 1 |
| Convery, ME; Domino, EF; Selden, EM; Stites, MM | 1 |
| Baran, L; Przegaliñski, E; Rokosz-Pelc, A; Vetulani, J | 1 |
| Dorey, RC; Preskorn, SH; Widener, PK | 1 |
| Aitken, DH; Bodnoff, SR; Meaney, MJ; Quirion, R; Suranyi-Cadotte, B | 1 |
| Bowden, CL; Brunswick, D; Carl, J; Frazer, A; Hanin, I; Kocsis, JH; Koslow, SH; Robins, E | 1 |
| Atwood, C; Beck, NC; Brownlee-Duffeck, M; Elliott, TR; Frank, RG; Haut, AE; Kashani, JH; Kay, DR; Parker, JC; Smith, E | 1 |
| Davidson, RK; Dilsauer, SC; Hariharen, M | 1 |
| Baumann, P; Cuendet, C; Eap, CB | 1 |
| Tajti, J | 1 |
| Collins, C; Hu, M; Izutsu, A; Jaklitsch, A; Pankey, S; Pirio, M; Singh, P | 1 |
| Bertilsson, L; Sjöqvist, F | 1 |
| Weller, EB; Weller, RA | 1 |
| Barouche, F; Fieve, RR; Goldring, N; Peselow, ED; Stanley, M | 1 |
| Bredehoeft, SJ; Chaturvedi, AK; Hidding, JT; Rao, NG; Smith, JC | 1 |
| Coscina, DV; Nobrega, JN | 1 |
| Adan, F; Allen, D; Coccaro, EF; Cooper, TB | 1 |
| Mahapatra, D; Mahapatra, RK; Paul, SK; Winter, S | 1 |
| Gordon, NC; Levine, JD; McBryde, R; Smith, R | 1 |
| Akah, PA | 1 |
| Tayo, FM | 1 |
| Newman, GC | 1 |
| Chamberlain, K; Curtis, G; Falcon, S; Ryan, C | 1 |
| Lydiard, RB | 1 |
| Coble, PA; Dealy, RS; Griffin, SJ; Grochocinski, VJ; Kupfer, DJ; McEachran, AB; Perel, JM; Shipley, JE; Ulrich, R | 1 |
| Dailey, JW; Jobe, PC | 1 |
| Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF | 1 |
| Borenstein, M; Brenner, R; Cooper, TB; Kane, JM; Lieberman, JA; Steinberg, H; Suckow, RF | 1 |
| Baldessarini, RJ; Cohen, BM | 1 |
| Fabian, A; Fields, HL; Pazoles, CJ; Taiwo, YO | 1 |
| Birgersson, C; Ericsson, O; Göransson, M; Henthorn, T; Sjöqvist, F; Spina, E; von Bahr, C | 1 |
| Kameyama, T; Nagasaka, M; Yamada, K | 1 |
| La Rue, A; Spar, JA | 1 |
| Boyer, WT | 1 |
| Frisk-Holmberg, M; van der Kleijn, E | 1 |
| al-Sarraj, S; Beckett, AH | 1 |
| Tuomisto, J | 1 |
| Schmutz, J | 1 |
| Squires, RF | 1 |
| McNair, DM | 1 |
| Coffer, AI; McDowall, RD; Robinson, AE | 1 |
| Mandell, AJ; Spooner, CE; Wallach, MB; Winters, WD | 2 |
| Bolan, JC; Glenn, CH; Hardison, MD; Mason, RG; Mohammad, SF; Morton, BD | 1 |
| Bhargava, KP; Saxena, PR; Seth, PK; Tangri, KK | 1 |
| Glasser, H; Krieglstein, J | 1 |
| Chichmanian, RM; Goude, F; Lanza, M | 1 |
| Medzihradsky, F; Nandhasri, PS | 1 |
| Creech, BJ; Smith, KR | 1 |
| Zingales, I | 1 |
| Hartmann, E | 1 |
| Zung, WW | 2 |
| Clineschmidt, BV; Pierce, JE; Sjoerdsma, A | 1 |
| Kodama, T; Matsukado, Y; Shimizu, H; Suzuki, T; Tanaka, S | 1 |
| Kaniike, K; Kurogochi, Y | 1 |
| Berndt, S; Schwabe, U | 1 |
| Gaut, ZN | 2 |
| Cater, BR; Chapman, D; Hawes, SM; Saville, J | 1 |
| Gyermek, L; Hill, RT; Sigg, EB | 1 |
| Fassina, G; Santi, R | 1 |
| Green, AL | 1 |
| Garattini, S; Jori, A; Paglialunga, S | 1 |
| Otten, U; Zetler, G | 1 |
| Tait, AC; Todrick, A | 1 |
| Carlsson, A; Jonason, J; Lindqvist, M | 1 |
| Chandra, O; Dhawan, KN; Gupta, GP; Saxena, RC | 1 |
| Colson, SH; Tolson, WW; Umberger, EJ | 1 |
| Nybäck, H; Schubert, J; Sedvall, G | 1 |
| Sturman, G | 1 |
| Fuxe, K; Jonsson, G; Lidbrink, P | 1 |
| Schrold, J | 1 |
| Lapin, IP; Oxenkrug, GF | 1 |
| Karobath, M | 1 |
| Bareggi, SR; Bonaccorsi, A; Franco, R; Garattini, S; Morselli, PL; Mundo, AS; Riva, E | 1 |
| Imai, S; Ogura, C; Okuma, T; Uchida, Y; Yogi, H | 1 |
| Markham, CH | 1 |
| Blank, HR; Greenberg, HR | 1 |
| Cataldi, S; Coscia, L; Marmo, E | 1 |
| Gripenberg, J | 1 |
| Biel, JH; Bopp, B | 1 |
| Bonaccorsi, A; Garattini, S; Jori, A; Samanin, R | 1 |
| Berner, P; Kryspin-Exner, K; Poeldinger, W | 1 |
| Fung, HL; Ow, YH | 1 |
| Baumgarten, HG | 1 |
| O'Malley, K; Sawyer, PR; Stevenson, IH | 1 |
| König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P | 1 |
| Bocknik, SE; Kulkarni, AS | 1 |
| Gaffney, T; Gard, H; Hanenson, I; Knapp, D; Walle, T | 1 |
| Connor, JD; Crawford, IL; Pardridge, WM | 1 |
| van Spanning, HW; van Zwieten, PA | 1 |
| Boulu, R; Dupeyron, JP; Rossignol, P | 1 |
| Browning, M; O'Malley, K; Stevenson, I; Turnbull, MJ | 1 |
| Lassen, JB | 1 |
| Mattila, MJ; Saarnivaara, L | 1 |
| Falk, MA | 1 |
| Furlong, FW; Luby, ED | 1 |
| Suchenwirth, R | 1 |
| Brody, TM; Commarato, MA; McNeill, JH | 1 |
| Deza, PC; Marjerrison, G; Silzer, JC | 1 |
| Kowa, Y; Nose, T | 1 |
| Constantine, JW; Koe, BK | 1 |
| Borg, KO; Lagerström, PO; Westerlund, D | 1 |
| Maickel, RP; Sokol, GH | 1 |
| Andreeva, NI | 1 |
| Aghajanian, GK; Sheard, MH; Zolovick, A | 1 |
| Attree, T; Sawyer, P; Turnbull, MJ | 1 |
| Atkinson, J; Ladinsky, H | 1 |
| Baumann, D | 1 |
| Brand, U; Menge, HG | 1 |
| Garriott, JC; Stolman, A | 1 |
| Brown, TC; Dwyer, ME; Stocks, JG | 1 |
| Huber, G | 1 |
| Oates, JA; Shand, DG | 1 |
| Appel, P; Eckel, K; Harrer, G | 1 |
| De Carolis, AS; Del Basso, P; Longo, VG; Ziegler, H | 1 |
| Luthe, R; Schmitt, W | 1 |
| Bhargava, KP; Chandra, O; Dixit, KS; Sinha, JA; Srimal, RC | 1 |
| Jaju, BP; Sinha, JN; Srimal, RC | 1 |
| Hitomi, M; Kumada, S; Kumadaki, N | 1 |
| Bodi, T; Dykyj, R; Mapp, Y; Nodine, JH; Siegler, PE | 1 |
| Azarnoff, DL; Borgå, O; Forshell, GP; Sjöqvist, F | 1 |
| Rohte, O | 2 |
| Dodge, GA; Logue, MA; Schildkraut, JJ | 1 |
| Alpers, HS; Himwich, HE | 1 |
| Scanlon, FJ | 1 |
| Gröningsson, K; Schill, G | 1 |
| Gross, R; Linker, H; Reuter, H | 1 |
| Fischbach, R | 2 |
| Greeff, K; Wagner, J | 2 |
| Opitz, K; Schniedermann, W | 1 |
| Lippmann, W | 1 |
| Alabaster, VA; Bakhle, YS | 2 |
| Núnek, K | 1 |
| Ose, E | 1 |
| Foxwell, MH; Funderburk, WH; Hakala, MW | 1 |
| Feighner, J; Robins, E; Schuckit, M | 1 |
| Avni, J; Edelstein, EL; Khazan, N; Sulman, FG | 1 |
| Corsico, N; Martelli, EA; Segre, AD; Tóth, E | 1 |
| Borchert, U; Opitz, K | 2 |
| Teien, A | 1 |
| Axelrod, J; Eccleston, D; Thoa, NB | 1 |
| Brody, TM; McNeill, JH | 1 |
| Barnett, A; Greenhouse, DD; Taber, RI | 1 |
| Andrási, F; Borsy, J | 1 |
| Milner, G | 1 |
| Zetler, G | 1 |
| Vaillant, GE | 1 |
| Eble, JN; Shriver, KL; Trepanier, DL | 1 |
| Scriabine, A | 1 |
| Beattie, RR; Freeman, JW; Mundy, GR; Ryan, C | 1 |
| Heilig, P; Heiss, WD; Hoyer, J | 2 |
| Murad, JE; Shore, PA | 1 |
| Bhargava, KP; Chandra, O; Dixit, KS; Sinha, JN; Srimal, RC | 1 |
| Gliozzi, E; Pacini, S; Pepeu, G | 1 |
| Battegay, R; Kahr, H; Pöldinger, W | 1 |
| Fischbach, R; Harrer, G; Harrer, H | 1 |
| Angst, J; Cornu, F; Dick, P; Heimann, H; Poeldinger, W | 1 |
| Angst, J; Poeldinger, W | 1 |
| Schmitt, H | 1 |
| Bhargava, KP; Gupta, ML; Gupta, TK | 1 |
| Hammer, W; Sjöqvist, F | 1 |
| Ropert, R; Sivadon, P | 1 |
| Lloyd, KG; Pilc, A | 1 |
| Brown, WA; Haier, RJ; Qualls, CB | 2 |
| Lippmann, W; Pugsley, TA | 1 |
| Reilly, MA; Sigg, EB | 1 |
| Crews, FT; Scott, JA; Shorstein, NH | 1 |
| Edström, A; Ekström, P; Kanje, M | 1 |
| Kupfer, D | 1 |
| Buchsbaum, M; Dubyoski, T; Johnson, J; Linnoila, M; Potter, WZ; Ross, R; Weingartner, H | 1 |
| Buchsbaum, MS; Dubyoski, K; Johnson, J; Kilts, C; Linnoila, M; Schneinin, M | 1 |
| Aronstam, RS | 1 |
| Bradshaw, CM; Gaszner, P; Szabadi, E | 4 |
| Chang, RS; Kling, P; Lotti, VJ | 1 |
| García-Sevilla, JA; Hollingsworth, PJ; Smnith, CB | 1 |
| Coscina, DV; Dumbrille-Ross, A; Tang, SW | 1 |
| Aghajanian, GK; Gallager, DW; Menkes, DB | 1 |
| Aghajanian, GK; Davis, M; Gallager, DW; Kehne, JH; Menkes, DB | 1 |
| Davies, CL; Green, AR; Heal, DJ; Lister, S; Molyneux, SG; Smith, SL | 1 |
| Bradley, L; Doggrell, SA | 1 |
| Caillé, G; Cournoyer, G; de Montigny, C; Langlois, R; Morissette, R | 1 |
| Charney, DS; Heninger, GR; Sternberg, DE | 3 |
| Garvey, MJ; Schaffer, CB; Tuason, VB | 1 |
| Dyr, W; Kostowski, W; Zacharski, B | 1 |
| Cutler, NR; Narang, PK | 1 |
| Bradford, D; Krijzer, F; Snelder, M | 1 |
| Cooke, RG; Persad, E; Reed, KL; Stancer, HC; Warsh, JJ | 1 |
| Charney, DS; Heninger, GR; Price, LH | 1 |
| Orsulak, PJ; Sink, M; Weed, J | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S | 1 |
| Garvey, MJ; Johnson, RA; Schuster, V; Valentine, RH | 1 |
| Arnt, J; Larsen, JJ | 1 |
| Feinberg, M; Genero, N; Greden, JF; Levine, S; Price, HL | 1 |
| Carter, RB; Leander, JD | 1 |
| Greer, NL; Schechter, MD | 1 |
| Beierle, FA; Hubbard, RW | 1 |
| Schechter, MD | 1 |
| Balázs, M; Fekete, M; Kádár, T; Telegdy, G | 1 |
| Clarke, RJ; Kraus, RP; Remick, RA | 1 |
| Lapierre, YD; Waters, BG | 1 |
| O'Donnell, JM; Rider, DP; Seiden, LS; Somani, S | 1 |
| Claghorn, JL; Mathew, RJ; Reck, JJ; Thapar, R; Weinman, ML | 1 |
| Vinet, B | 1 |
| Briley, MS; Langer, SZ; Sette, M | 1 |
| Bielski, RJ; Bloom, V; Fawcett, JA; Friedel, RO; Narasimhachari, N; Veith, RC | 1 |
| Kimelberg, HK; Pelton, EW | 1 |
| Bagri, S; Fawcett, J; Javaid, JI; Sabelli, HC | 1 |
| Isenberg, K; Livingston, RL; Wetzel, RD; Zucker, DK | 1 |
| Brown, RP; Frances, A; Kocsis, JH; Loutsch, E; Sweeney, J | 1 |
| Clody, DE; Eisenstein, N; Iorio, LC | 1 |
| Brown, WA; Qualls, CB | 1 |
| Kwan, S; Seeman, P; Tang, SW | 1 |
| Gold, P; Linnoila, M; Potter, WZ; Wehr, TA | 1 |
| Davis, C; Ho, BT; Mathew, RJ; Reck, J; Taylor, D | 1 |
| Amsterdam, J; Brunswick, D; Mendels, J | 1 |
| Forker, AD; Marshall, JB | 1 |
| Claghorn, JL; Ho, BT; Khan, MM; Mathew, RJ; Perales, C; Weinman, ML | 1 |
| Goodwin, FK; Lipton, MA; Muscettola, G; Post, RM; Prange, AJ | 1 |
| Mendlewicz, J; Razavi, D | 1 |
| Lyskowksi, J; Nasrallah, HA; Schroeder, D | 1 |
| Keller, JM; Kwong, TC; Martinez, R | 1 |
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| Graham, BG; Sattely-Miller, EA; Schiffman, SS; Suggs, MS | 1 |
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| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
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31 review(s) available for amitriptyline and desipramine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine | 1976 |
Drug impairment reviews: opiates, minor tranquilizers.
Topics: Amitriptyline; Anti-Anxiety Agents; Automobile Driving; Behavior; Desipramine; Dextropropoxyphene; Diazepam; Ethanol; Humans; Imipramine; Lithium; Methadone; Motor Skills; Narcotics; Task Performance and Analysis | 1977 |
Clinical and biochemical heterogeneity of depressive disorders.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Depression; Desipramine; Dextroamphetamine; Emotions; Humans; Imipramine; Metanephrine; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Norepinephrine; Normetanephrine; Vanilmandelic Acid | 1978 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; Depression; Desipramine; Doxepin; Humans; Imipramine; Kinetics; Neurotransmitter Agents; Nortriptyline; Protriptyline | 1978 |
Poisoning by tricyclic antidepressant drugs: general and pharmacokinetic considerations.
Topics: Accidents, Home; Adolescent; Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain Chemistry; Child; Child, Preschool; Desipramine; Dibenzazepines; Drug Interactions; Female; Humans; Imipramine; Infant; Intestinal Absorption; Kinetics; Liver; Lung; Male; Mice; Middle Aged; Nortriptyline; Opipramol; Poisoning; Protein Binding; Rats; Suicide | 1975 |
Toleration and safety of sertraline: experience worldwide.
Topics: 1-Naphthylamine; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Drug Overdose; Humans; Risk Factors; Sertraline | 1991 |
Slow hydroxylation of tricyclic antidepressants--relationship to polymorphic drug oxidation.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Debrisoquin; Desipramine; Female; Humans; Hydroxylation; Kinetics; Male; Middle Aged; Nortriptyline; Phenotype; Polymorphism, Genetic; Smoking; Twins, Dizygotic; Twins, Monozygotic | 1986 |
Tricyclic-resistant depression: treatment resistance or inadequate treatment?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Humans; Imipramine; Intestinal Absorption; Kinetics; Nortriptyline; Patient Compliance | 1985 |
[Intention and incident in drug research, demonstrated on the example of tricyclic psychopharmacologic agents].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Azepines; Chemical Phenomena; Chemistry; Chlorpromazine; Desipramine; Humans; Imipramine; Mental Disorders; Research; Structure-Activity Relationship; Tranquilizing Agents | 1973 |
Self-evaluations of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipramine; Dextroamphetamine; Diazepam; Doxepin; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methylphenidate; MMPI; Nialamide; Pargyline; Placebos; Psychiatric Status Rating Scales; Psychological Tests; Statistics as Topic; Thioridazine; Tranylcypromine | 1974 |
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan | 1969 |
Antidepressant drugs and sleep.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Arousal; Brain; Cats; Depression; Desipramine; Electroencephalography; Electromyography; Electrooculography; Female; Humans; Imipramine; Male; Monoamine Oxidase Inhibitors; Sleep; Sleep, REM | 1969 |
The pharmacology of disordered sleep: a laboratory approach.
Topics: Amitriptyline; Anxiety; Arousal; Barbiturates; Brain; Cerebral Cortex; Depression; Desipramine; Humans; Hypothalamus; Imipramine; Limbic System; Meprobamate; Phenothiazines; Reticular Formation; Schizophrenia; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Thalamus | 1970 |
Antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Carbazoles; Chlorpromazine; Desipramine; Imipramine; Molecular Conformation; Opipramol; Structure-Activity Relationship; Tripelennamine | 1974 |
[Monoamines and the pharmacological effects of tricyclic antidepressive agents].
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Central Nervous System; Chemical Phenomena; Chemistry; Desipramine; Humans; Hydroxyindoleacetic Acid; Imipramine; Methyltransferases; Monoamine Oxidase; Norepinephrine; Nortriptyline; Receptors, Drug; Serotonin | 1972 |
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Gastric Mucosa; Glomerular Filtration Rate; Humans; Imipramine; Kinetics; Middle Aged; Nordazepam; Nortriptyline | 1984 |
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Imipramine; Nortriptyline; Protriptyline | 1980 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Child; Depression; Desipramine; Doxepin; Electrocardiography; Hemodynamics; Humans; Hypotension; Imipramine; Kinetics; Middle Aged; Myocardium; Norepinephrine; Parasympatholytics; Protriptyline | 1982 |
Tricyclic medication in children and the QT interval: case report and discussion.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; Contraindications; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Imipramine; Long QT Syndrome; Nortriptyline; Practice Guidelines as Topic | 1995 |
Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; ROC Curve; Sensitivity and Specificity | 1994 |
Postherpetic neuralgia and its managements.
Topics: Amitriptyline; Analgesics; Desipramine; Herpes Zoster; Humans; India; Neuralgia | 1993 |
[Tricyclic antidepressants (imipramine, desipramine, amitriptyline, nortriptyline)].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Drug Monitoring; Humans; Imipramine | 1995 |
[Pharmacological treatment of delusional depression].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Delusions; Depressive Disorder; Desipramine; Drug Therapy, Combination; Haloperidol; Humans; Perphenazine; Psychotic Disorders | 1996 |
Tricyclic antidepressant use in diabetic neuropathy.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Diabetic Neuropathies; Humans | 1999 |
CURRENT STATUS OF DRUG TREATMENT IN THE DEPRESSIVE STATE.
Topics: Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Aspartic Acid; Benactyzine; Classification; Deanol; Depression; Desipramine; Humans; Imipramine; Isocarboxazid; Methylphenidate; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Pharmacology; Phenelzine; Phenmetrazine; Piperidines; Sympathomimetics; Toxicology; Tranylcypromine | 1964 |
THE PHARMACOTHERAPY OF THE DEPRESSIVE SYNDROME.
Topics: Amitriptyline; Antidepressive Agents; Convulsive Therapy; Depression; Depressive Disorder; Desipramine; Drug Therapy; Electroconvulsive Therapy; Imipramine; Mental Disorders; Monoamine Oxidase Inhibitors; Psychopharmacology; Psychotherapy; Toxicology; Tranquilizing Agents | 1965 |
THE ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Depression; Depressive Disorder; Desipramine; Drug Therapy; Epidemiology; Humans; Imipramine; Mental Disorders; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Psychopharmacology | 1965 |
Desipramine for neuropathic pain in adults.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desipramine; Diabetic Neuropathies; Fluoxetine; Humans; Middle Aged; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2014 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
36 trial(s) available for amitriptyline and desipramine
| Article | Year |
|---|---|
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Double-Blind Method; Drug Interactions; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mianserin; Propranolol | 1978 |
A comparison of desipramine and amitriptyline plasma levels and therapeutic response.
Topics: Adjustment Disorders; Adult; Amitriptyline; Clinical Trials as Topic; Depression; Desipramine; Double-Blind Method; Humans; Middle Aged | 1978 |
Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Biopharmaceutics; Clinical Trials as Topic; Depression; Desipramine; Doxepin; Erythrocytes; Humans; Imipramine; Middle Aged; Nortriptyline | 1978 |
Desipramine plasma levels and clinical response in depressed outpatients.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depression; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychological Tests | 1979 |
Anticholinergic activity of two tricyclic antidepressants.
Topics: Adult; Amitriptyline; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Parasympatholytics; Salivation; Sleep Stages; Structure-Activity Relationship; Time Factors | 1978 |
Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Depression; Desipramine; Diabetic Neuropathies; Double-Blind Method; Female; Fluoxetine; Humans; Infant, Newborn; Male; Middle Aged; Pain | 1992 |
Abnormal cortisol dynamics after traumatic brain injury. Lack of utility in predicting agitation or therapeutic response to tricyclic antidepressants.
Topics: Adolescent; Adult; Amitriptyline; Arousal; Brain Injuries; Clinical Trials as Topic; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middle Aged; Prognosis; Psychomotor Agitation; Random Allocation | 1989 |
Reduced REM latency predicts response to tricyclic medication in depressed outpatients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychological Tests; Random Allocation; Reaction Time; Sleep, REM | 1989 |
Desipramine increases circulating growth hormone in elderly depressed patients: a pilot study.
Topics: Aged; Aged, 80 and over; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans; Hydrocortisone; Male; Middle Aged; Pilot Projects; Prolactin; Random Allocation | 1989 |
Antidepressants in 'depressed' schizophrenic inpatients. A controlled trial.
Topics: Adolescent; Adult; Amitriptyline; Benztropine; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Hospitalization; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1989 |
Measuring results of treatment of PTSD.
Topics: Amitriptyline; Clinical Trials as Topic; Combat Disorders; Desipramine; Double-Blind Method; Humans; Male; Research Design; Stress Disorders, Post-Traumatic | 1989 |
Antidepressant-induced weight gain: a comparison study of four medications.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline; Weight Gain; Zimeldine | 1988 |
Antidepressant analgesia in rheumatoid arthritis.
Topics: Aged; Amitriptyline; Antidepressive Agents; Arthritis, Rheumatoid; Depression; Desipramine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain; Random Allocation; Trazodone | 1988 |
Tricyclic antidepressants in prepubertal depressed children: review of the literature.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Humans; Imipramine | 1986 |
The dexamethasone suppression test (DST) in predicting response to desipramine and amitriptyline in depressed outpatients.
Topics: Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dexamethasone; Humans; Hydrocortisone; Predictive Value of Tests | 1986 |
Desipramine enhances opiate postoperative analgesia.
Topics: Amitriptyline; Analgesia; Desipramine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Humans; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Period; Preanesthetic Medication; Time Factors | 1986 |
Treatment of progressive supranuclear palsy with tricyclic antidepressants.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bulbar Palsy, Progressive; Clinical Trials as Topic; Desipramine; Disability Evaluation; Eye Movements; Female; Humans; Male; Middle Aged | 1985 |
Tricyclics: possible treatment for posttraumatic stress disorder.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Combat Disorders; Desipramine; Doxepin; Humans; Imipramine; Male; Manuals as Topic; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Stress Disorders, Post-Traumatic | 1985 |
Comparison of effects of desipramine and amitriptyline on EEG sleep of depressed patients.
Topics: Adult; Amitriptyline; Depression; Desipramine; Double-Blind Method; Electroencephalography; Female; Humans; Male; Middle Aged; Sleep; Sleep, REM | 1985 |
Self-evaluations of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Depression; Desipramine; Dextroamphetamine; Diazepam; Doxepin; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methylphenidate; MMPI; Nialamide; Pargyline; Placebos; Psychiatric Status Rating Scales; Psychological Tests; Statistics as Topic; Thioridazine; Tranylcypromine | 1974 |
Therapy possibilities for therapy-resistant depressions.
Topics: Amitriptyline; Antidepressive Agents; Chronic Disease; Clinical Trials as Topic; Depression; Desipramine; Drug Resistance; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Imipramine; Nortriptyline; Remission, Spontaneous; Time Factors; Tranquilizing Agents | 1974 |
Lithium in the control of mania.
Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine; Trifluoperazine | 1967 |
Verbal behaviour changes with depression treatment.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Imipramine; Interpersonal Relations; Interview, Psychological; Male; Middle Aged; Nortriptyline; Placebos; Psychiatric Status Rating Scales; Self Concept; Verbal Behavior | 1969 |
A variable dose phase 3, human bioassay of nortriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1965 |
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doxepin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Lithium Carbonate; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Serotonin; Trimipramine | 1983 |
Lithium carbonate augmentation of antidepressant treatment. An effective prescription for treatment-refractory depression.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Male; Mianserin; Middle Aged; Psychiatric Status Rating Scales | 1983 |
Serotonin function and mechanism of action of antidepressant treatment. Effects of amitriptyline and desipramine.
Topics: Aged; Amitriptyline; Animals; Brain Chemistry; Depressive Disorder; Desipramine; Female; Humans; Infant; Infusions, Parenteral; Male; Middle Aged; Placebos; Prolactin; Rats; Receptors, Serotonin; Serotonin; Stimulation, Chemical; Substance Withdrawal Syndrome; Time Factors; Tryptophan | 1984 |
Urinary MHPG excretion and treatment with desipramine or amitriptyline: prediction of response, effect of treatment, and methodological hazards.
Topics: Adult; Amitriptyline; Anxiety; Depressive Disorder; Desipramine; Female; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Time Factors | 1983 |
ECG effects of comparable plasma concentrations of desipramine and amitriptyline.
Topics: Adult; Amitriptyline; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged | 1982 |
Comparison of the peripheral anticholinergic activities of desipramine and amitriptyline in healthy volunteers [proceedings].
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Male; Parasympatholytics | 1980 |
Comparison of the effects of desipramine and amitriptyline on pupillary responses to noradrenaline and methoxamine in healthy volunteers [proceedings].
Topics: Adult; Amitriptyline; Desipramine; Drug Interactions; Female; Humans; Male; Methoxamine; Norepinephrine; Pupil | 1980 |
The peripheral anticholinergic activity of tricyclic antidepressants: comparison of amitriptyline and desipramine in human volunteers.
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Male; Parasympatholytics; Placebos; Pulse; Pupil; Salivation; Sweating | 1980 |
Prospective assessment of electroencephalographic sleep in remitted major depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cerebral Cortex; Cognitive Behavioral Therapy; Combined Modality Therapy; Depressive Disorder; Desipramine; Double-Blind Method; Electroencephalography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Polysomnography; Sleep Stages | 1993 |
Significance of monitoring plasma levels of amitriptyline, and its hydroxylated and desmethylated metabolites in prediction of the clinical outcome of depressive state.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Dealkylation; Depressive Disorder; Desipramine; Female; Humans; Hydroxylation; Male; Middle Aged; Prognosis; Treatment Outcome | 1997 |
The effects of antidepressants on obstructed and unobstructed gait in healthy elderly people.
Topics: Affect; Aged; Amitriptyline; Antidepressive Agents; Desipramine; Double-Blind Method; Female; Gait; Humans; Male; Paroxetine; Psychomotor Performance; Risk Factors; Selective Serotonin Reuptake Inhibitors | 2001 |
Treatment response in antidepressant-naïve postherpetic neuralgia patients: double-blind, randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Double-Blind Method; Female; Fluoxetine; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Patient Dropouts; Treatment Outcome | 2005 |
428 other study(ies) available for amitriptyline and desipramine
| Article | Year |
|---|---|
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 5. Conformationally mobile analogues derived by furan ring opening.
Topics: Animals; Antidepressive Agents; Benzofurans; Brain; In Vitro Techniques; Mice; Norepinephrine; Piperidines; Rats; Spiro Compounds; Structure-Activity Relationship; Synaptosomes; Tetrabenazine | 1979 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles | 1988 |
Synthesis and antidepressant profiles of phenyl-substituted 2-amino- and 2-[(alkoxycarbonyl)amino]-1,4,5,6-tetrahydropyrimidines.
Topics: Amines; Animals; Antidepressive Agents; Dopamine; Mice; Norepinephrine; Pyrimidines; Structure-Activity Relationship | 1985 |
Tetracyclic pyridazines as potential psychopharmacological agents.
Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Chlorprothixene; Isomerism; Magnetic Resonance Spectroscopy; Mice; Norepinephrine; Psychotropic Drugs; Pyridazines; Rats; Serotonin; Structure-Activity Relationship | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
7-(Aminoacyl) and 7-(aminoalkyl) derivatives of 1,2,6,7-tetrahydroindolo[1,7-ab][1,5]benzodiazepines as potential antidepressant agents.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Chemical Phenomena; Chemistry; Rats; Structure-Activity Relationship | 1980 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Novel tetracyclic spiropiperidines. 3. 1-arylspiro[indoline-3,4'-piperidine]s as potential antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Biological Assay; Blepharoptosis; Drug Synergism; Humans; Indicators and Reagents; Indoles; Piperidines; Stereotyped Behavior; Structure-Activity Relationship; Tetrabenazine | 1983 |
Novel tetracyclic spiropiperidines. 1. 3-Aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidines] as potential antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Chemical Phenomena; Chemistry; Drug Synergism; Male; Mice; Physostigmine; Piperidines; Spiro Compounds; Tetrabenazine | 1981 |
(+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 1. Synthesis and evaluation of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and analogues as potential antidepressant agents.
Topics: Aggression; Animals; Antidepressive Agents; Benzodiazepines; Biogenic Amines; Chemical Phenomena; Chemistry; Drug Interactions; Humans; In Vitro Techniques; Male; Mice; Monoamine Oxidase Inhibitors; Oxotremorine; Rats; Rats, Inbred Strains; Synaptosomes; Yohimbine | 1982 |
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 6. Synthesis, 13C NMR, and biological evaluation of cis- and trans-4-amino-3'-arylspiro[cyclohexane-1,1'(3'H)-isobenzofuran] derivatives.
Topics: Animals; Antidepressive Agents; Benzofurans; Chemical Phenomena; Chemistry; Drug Synergism; Magnetic Resonance Spectroscopy; Male; Rats; Seizures; Spiro Compounds; Stereoisomerism; Tetrabenazine | 1981 |
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Toward prediction of alkane/water partition coefficients.
Topics: Alkanes; Central Nervous System; Molecular Structure; Static Electricity; Surface Properties; Water | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.
Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface | 2014 |
Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Injections, Intraperitoneal; Isoxazoles; Ligands; Mice; Mice, Inbred Strains; Molecular Structure; Pain; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship | 2016 |
NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation.
Topics: Apoptosis; Cell Line; Cells, Cultured; Ceramides; Enzyme Inhibitors; Humans; Inflammation; Lipopolysaccharides; Lysosomes; Macrophages; Signal Transduction; Sphingomyelin Phosphodiesterase | 2018 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
C-terminal modified Enkephalin-like tetrapeptides with enhanced affinities at the kappa opioid receptor and monoamine transporters.
Topics: Amides; Dose-Response Relationship, Drug; Humans; Ligands; Models, Molecular; Molecular Structure; Oligopeptides; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2021 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
The neuropharmacology of depression.
Topics: Amitriptyline; Brain; Brain Chemistry; Depression; Desipramine; Dopamine; Humans; Imipramine; Models, Neurological; Neurotransmitter Agents; Norepinephrine; Serotonin; Synaptic Transmission | 1977 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic | 1979 |
The effect of tricyclic antidepressants on corticofugal inhibition of the spinal trigeminal nucleus.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brompheniramine; Cats; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Drug Combinations; Imipramine; Neural Inhibition; Procyclidine; Spinal Cord; Trigeminal Nerve | 1977 |
Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking Behavior; Fenclonine; Imipramine; Male; Methyltyrosines; Nortriptyline; Protriptyline; Rats; Water Deprivation | 1977 |
Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs.
Topics: Alcohol Oxidoreductases; Amitriptyline; Animals; Chlorpromazine; Desipramine; Dibenzocycloheptenes; Enzyme Activation; Hydroxyprostaglandin Dehydrogenases; Imipramine; Kidney; Kinetics; NAD; Protriptyline; Swine | 1976 |
Enhancement of central norepinephrine and 5-hydroxytryptamine transmission by tricyclic antidepressants. A comparison.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Electric Stimulation; Female; Imipramine; Male; Norepinephrine; Serotonin; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Time Factors | 1979 |
The influence of desipramine and amitriptyline on the accumulation of [3-H]noradrenaline and its two major metabolites formed from [3-H]tyrosine in the rat brain.
Topics: Amitriptyline; Animals; Brain; Brain Chemistry; Depression, Chemical; Desipramine; Male; Norepinephrine; Rats; Tyrosine | 1975 |
Uptake of catecholamines by human cardiac muscle in vitro.
Topics: Adolescent; Adult; Aged; Amitriptyline; Atrial Function; Biological Transport; Child; Coronary Artery Bypass; Desipramine; Female; Heart; Heart Atria; Heart Diseases; Heart Valves; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Ouabain | 1979 |
High-affinity 3H-imipramine binding in rat cerebral cortex.
Topics: Amitriptyline; Animals; Binding Sites; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; In Vitro Techniques; Male; Rats | 1979 |
Electrocortical changes in the encéphale isolé cat following chronic treatment with antidepressant drugs.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Antidepressive Agents; Cats; Decerebrate State; Desipramine; Electroencephalography; Female; Imipramine; Male; Viloxazine | 1979 |
Effects of somatic treatments on mood in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clomipramine; Depression; Desipramine; Electroconvulsive Therapy; Emotions; Evaluation Studies as Topic; Female; Humans; Male; Maprotiline; Middle Aged; Psychological Tests; Time Factors | 1979 |
Guidelines for therapeutic monitoring of tricyclic antidepressant plasma levels.
Topics: Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Drug Interactions; Humans; Imipramine; Monitoring, Physiologic | 1979 |
Tricyclic antidepressant overdose: incidence of symptoms.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Electrocardiography; Heart; Humans; Imipramine; Nortriptyline | 1977 |
Chronic treatment with desipramine caused a sustained decrease of 3,4-dihydroxyphenylglycol-sulphate and total 3-methoxy-4-hydroxyphenylglycol in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Brain Chemistry; Catechols; Depression, Chemical; Desipramine; Dopamine; Ethylene Glycols; Glycols; Homovanillic Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Time Factors; Tyrosine | 1977 |
Liquid-chromatographic procedure for tricyclic drugs and their metabolites in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Humans; Imipramine; Nortriptyline | 1978 |
Determination of drugs in plasma by high-performance thin-layer chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1978 |
Tricyclic antidepressants: plasma levels and clinical findings in overdose.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Electrocardiography; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1978 |
High-performance liquid-chromatographic simultaneous determination of commonly used tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline | 1978 |
The effect of acute and chronic desipramine and amitriptyline treatment on rat brain total 3methoxy-4-hydroxyphenylglycol.
Topics: Amitriptyline; Animals; Brain Chemistry; Clonidine; Desipramine; Drug Interactions; Glycols; Male; Methoxyhydroxyphenylglycol; Rats; Time Factors | 1978 |
Tricyclic antidepressant overdoses in adolescent patients.
Topics: Adolescent; Affective Symptoms; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Doxepin; Female; Humans; Imipramine; Male; Substance-Related Disorders; Suicide, Attempted | 1977 |
Relationship between age and tricyclic antidepressant plasma levels.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Body Weight; Depression; Desipramine; Female; Half-Life; Heart; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1977 |
Effects of tricyclic antidepressants on the content and metabolism of dopamine in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Benztropine; Corpus Striatum; Desipramine; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Imipramine; Male; Rats; Time Factors | 1977 |
High-performance thin-layer chromatographic determination of psychopharmacologic agents in blood serum.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1977 |
Measurement of plasma levels of tricylic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms.
Topics: Amitriptyline; Chromatography, Thin Layer; Clozapine; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Perazine; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1976 |
Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities.
Topics: Amitriptyline; Animals; Apomorphine; Biogenic Amines; Brain; Desipramine; Drug Synergism; Gastric Juice; Imipramine; In Vitro Techniques; Levodopa; Mice; Morpholines; Myocardium; Norepinephrine; Oxotremorine; Pupil; Rats; Reflex; Reserpine; Serotonin; Tyramine; Viloxazine | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
The effect of amitriptyline, desipramine and imipramine on the vivo brain synthesis of 3H-noradrenaline from 3H-L-dopa in the rat.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Benserazide; Brain; Chromatography, Thin Layer; Desipramine; Dopamine; Imipramine; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Normetanephrine; Rats; Tryptamines | 1975 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1975 |
Interactions of tricyclic antidepressants and barbiturates in barbiturate-tolerant and nontolerant rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Barbiturates; Brain Chemistry; Desipramine; Drug Interactions; Drug Tolerance; Imipramine; Male; Microsomes, Liver; Nortriptyline; Pentobarbital; Rats; Sleep; Time Factors | 1975 |
Inhibition of prostaglandin synthetase by psychotropic drugs.
Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles | 1975 |
Tricyclic antidepressant agents. I. Comparison of the inhibition of the uptake of 3-H-noradrenaline and 14-C-5-hydroxytryptamine in slices and crude synaptosome preparations of the midbrain-hypothalamus region of the rat brain.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression, Chemical; Desipramine; Humans; Hypothalamus; Imipramine; Male; Mesencephalon; Norepinephrine; Serotonin; Synaptosomes; Time Factors | 1975 |
Tricyclic antidepressant agents. II. Effect of oral administration on the uptake of 3-H-noradrenaline and 14-C-5-hydroxytryptamine in slices of the midbrain-hypothalamus region of the rat.
Topics: Administration, Oral; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Desipramine; Hypothalamus; Imipramine; Male; Mesencephalon; Norepinephrine; Proadifen; Rats; Serotonin; Time Factors | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression.
Topics: Amitriptyline; Biogenic Amines; Depression; Desipramine; Dextroamphetamine; Humans; Hydroxyindoleacetic Acid; Imipramine; Metanephrine; Methoxyhydroxyphenylglycol; Normetanephrine; Nortriptyline; Vanilmandelic Acid | 1975 |
[Postsynaptic attack of tricyclic antidepressive agents in the circulatory system].
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Imipramine; Male; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Rats; Receptors, Drug | 1975 |
Amitriptyline, desipramine, cyproheptadine and carbamazepine, in concentrations used therapeutically, reduce kainate- and N-methyl-D-aspartate-induced intracellular Ca2+ levels in neuronal culture.
Topics: Amitriptyline; Animals; Calcium; Calcium Channel Blockers; Carbamazepine; Cells, Cultured; Cerebellum; Cyproheptadine; Desipramine; Kainic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 1992 |
Exercise and antidepressant serum levels.
Topics: Adult; Amitriptyline; Depressive Disorder; Desipramine; Exercise; Female; Humans; Metabolic Clearance Rate; Running | 1992 |
Changes in the amount and distribution of neuronal alkaline and acid phosphatase after chronic exposure of cultures of cingulate cortex to antidepressant drugs.
Topics: Acid Phosphatase; Alkaline Phosphatase; Amitriptyline; Animals; Antidepressive Agents; Cells, Cultured; Cerebral Cortex; Citalopram; Desipramine; Female; Histocytochemistry; Image Processing, Computer-Assisted; Mianserin; Neurons; Pregnancy; Rats; Rats, Wistar | 1992 |
Pharmacological comparison of the rat and guinea-pig cortical high affinity 5-hydroxytryptamine uptake system.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Citalopram; Desipramine; Female; Guinea Pigs; Kinetics; Nortriptyline; Rats; Serotonin; Synaptosomes | 1992 |
Tricyclic antidepressant-induced seizures and plasma drug concentration.
Topics: Adult; Ambulatory Care; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Administration Schedule; Drug Monitoring; Epilepsy, Tonic-Clonic; Female; Hospitalization; Humans; Imipramine; Incidence; Male; Middle Aged; Panic Disorder | 1992 |
Inhibition and metabolite complexation of rat hepatic microsomal cytochrome P450 by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desipramine; Hydroxylation; Imipramine; Male; Microsomes, Liver; Nortriptyline; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Testosterone | 1992 |
Effect of paroxetine, a selective 5-hydroxytryptamine uptake inhibitor, on beta-adrenoceptors in rat brain: autoradiographic and functional studies.
Topics: Adrenergic beta-Antagonists; Amitriptyline; Animals; Autoradiography; Brain Chemistry; Cyclic AMP; Desipramine; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Membranes; Paroxetine; Pindolol; Piperidines; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Serotonin Antagonists | 1991 |
Influence of antidepressant drugs on seizure susceptibility and the anticonvulsant activity of valproate in mice.
Topics: Amitriptyline; Animals; Desipramine; Dose-Response Relationship, Drug; Electroshock; Imipramine; Male; Mice; Seizures; Valproic Acid | 1991 |
Genotoxicity evaluation of five tricyclic antidepressants in the wing somatic mutation and recombination test in Drosophila melanogaster.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Imipramine; Mutagenicity Tests; Nortriptyline; Protriptyline; Recombination, Genetic | 1991 |
Evidence for feeding elicited through antihistaminergic effects of tricyclic antidepressants in the rat hypothalamus.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking; Eating; Histamine H1 Antagonists; Hypothalamus; Imipramine; Injections, Intraventricular; Male; Methylhistidines; Microinjections; Rats; Rats, Inbred Strains; Zimeldine | 1990 |
Use of tricyclic antidepressants in recipients of heart transplants.
Topics: Adaptation, Psychological; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Heart Transplantation; Humans; Middle Aged; Nortriptyline; Postoperative Complications | 1991 |
Extremely slow metabolism of amitriptyline but normal metabolism of imipramine and desipramine in an extensive metabolizer of sparteine, debrisoquine, and mephenytoin.
Topics: Administration, Oral; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Thin Layer; Debrisoquin; Desipramine; Drug Interactions; Humans; Imipramine; Male; Mephenytoin; Phenotype; Quinidine; Sparteine | 1991 |
Antinociceptive action of tricyclic antidepressant drugs in the rat.
Topics: Amitriptyline; Analgesia; Animals; Delayed-Action Preparations; Desipramine; Disease Models, Animal; Male; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Effects of systemically administered monoamine reuptake blocking agents on patterns of buspirone-induced analgesia in rats.
Topics: Amitriptyline; Analgesia; Animals; Brain Chemistry; Buspirone; Desipramine; Dopamine; Drug Interactions; Female; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Serotonin; Spinal Cord | 1990 |
[Therapeutic drug monitoring of tricyclic antidepressants].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biological Availability; Chromatography, Gas; Chromatography, High Pressure Liquid; Desipramine; Humans; Immunoenzyme Techniques; Nortriptyline | 1990 |
The effects of various antidepressant drugs on the fine-structure of neurons of the cingulate cortex in culture.
Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Cytoskeleton; Desipramine; Female; Gyrus Cinguli; Mianserin; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Inbred Strains; Synapses | 1990 |
Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Amitriptyline; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Desipramine; Dibenzoxazepines; Enzyme Induction; Humans; Imipramine; Injections, Intraperitoneal; Male; Mianserin; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenobarbital; Phenytoin | 1990 |
Inhibition of the retrograde axonal transport of acetylcholinesterase by the anti-calmodulin agents amitriptyline and desipramine.
Topics: Acetylcholinesterase; Amitriptyline; Animals; Axonal Transport; Calmodulin; Desipramine; Rana catesbeiana; Sciatic Nerve; Spinal Nerves | 1985 |
Inhibition of fast axonal transport in bullfrog nerves by dibenzazepine and dibenzocycloheptadiene calmodulin inhibitors.
Topics: Acetylcholinesterase; Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Calmodulin; Clomipramine; Desipramine; Ganglia, Spinal; Imipramine; In Vitro Techniques; Microtubules; Phosphocreatine; Rana catesbeiana; Spinal Nerves | 1986 |
Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebral Cortex; Chlorides; Desipramine; gamma-Aminobutyric Acid; Imipramine; Ion Channels; Ionophores; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1988 |
Effects of acute and chronic anti-panic drug administration on conflict behavior in the rat.
Topics: Amitriptyline; Animals; Conflict, Psychological; Desipramine; Drinking Behavior; Electroshock; Fear; Female; Panic; Phenelzine; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Strain-specific effects of antidepressants on escape deficits induced by inescapable shock.
Topics: Amitriptyline; Animals; Antidepressive Agents; Bupropion; Desipramine; Electroshock; Escape Reaction; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Propiophenones; Reaction Time; Receptors, Serotonin; Species Specificity | 1989 |
Antidepressant treatments, including sibutramine hydrochloride and electroconvulsive shock, decrease beta 1- but not beta 2-adrenoceptors in rat cortex.
Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Cerebral Cortex; Clenbuterol; Cyclobutanes; Desipramine; Dihydroalprenolol; Electroshock; Kinetics; Male; Rats; Receptors, Adrenergic, beta; Reference Values; Tranylcypromine; Zimeldine | 1989 |
External quality assurance of tricyclic antidepressant measurements in serum: eight years of progress?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Nortriptyline; Quality Control | 1989 |
Effect of tricyclic antidepressant drugs in the isolation-induced social behavioural deficit test.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Reference Values; Social Behavior; Social Isolation | 1989 |
Determination of serum desipramine and 2-hydroxydesipramine for pharmacokinetic applications by HPLC with ultraviolet detection.
Topics: Alkalies; Amitriptyline; Chromatography, High Pressure Liquid; Desipramine; Humans; Microchemistry; Spectrometry, Fluorescence; Time Factors | 1989 |
Dose-dependent down-regulation of beta-adrenergic receptors after chronic intravenous infusion of antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebral Cortex; Cyclopentanes; Desipramine; Dose-Response Relationship, Drug; Female; Imipramine; Infusions, Intravenous; Iprindole; Kinetics; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values; Zimeldine | 1988 |
The nucleus accumbens and antidepressants: modulation of ergometrine-induced hyperactivity by typical and atypical antidepressants and neuroleptics in rats.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Clorgyline; Clozapine; Desipramine; Ergonovine; Male; Mianserin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sulpiride; Zimeldine | 1987 |
Antidepressants and EEG sleep: search for specificity.
Topics: Amitriptyline; Antidepressive Agents; Depressive Disorder; Desipramine; Humans; Nortriptyline; Sleep; Sleep Stages; Zimeldine | 1987 |
Comparison of desipramine, amitriptyline, zimeldine and alaproclate in six animal models used to investigate antidepressant drugs.
Topics: Alanine; Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Desipramine; Male; Rats; Rats, Inbred Strains; Time Factors; Zimeldine | 1988 |
Why is amitriptyline much weaker than desipramine at decreasing beta-adrenoceptor numbers?
Topics: Amitriptyline; Animals; Desipramine; In Vitro Techniques; Male; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Desensitization of beta-receptors on primary astrocyte cultures by norepinephrine but not by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Astrocytes; Cells, Cultured; Cyclic AMP; Desipramine; Iodocyanopindolol; Norepinephrine; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1985 |
Adaptive and differential changes on beta- and alpha 2-adrenoreceptors mediated hyperthermia after chronic treatment with antidepressant drugs in the rat kept at high ambient temperature.
Topics: Amitriptyline; Animals; Body Temperature; Brain; Desipramine; Environment; Hot Temperature; Hyperthermia, Induced; Imipramine; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1985 |
Effects of combined administration of L-tryptophan and tricyclic antidepressants on alpha 2- and beta-adrenoceptors and monoamine levels in rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Catecholamines; Desipramine; Drug Combinations; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Time Factors; Tryptophan | 1985 |
Pharmacologic evidence that high dose chronic amitriptyline and desipramine down-regulate alpha 2-receptor-mediated hypothermia in the rat.
Topics: Amitriptyline; Animals; Body Temperature Regulation; Chromatography, High Pressure Liquid; Clonidine; Desipramine; Half-Life; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Repeated treatment with antidepressant drugs does not affect the benzodiazepine receptors in preincubated membrane preparations from mouse and rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Desipramine; Flunitrazepam; Imipramine; Male; Mice; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Results compared for tricyclic antidepressants as assayed by liquid chromatography and enzyme immunoassay.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Immunoenzyme Techniques; Nortriptyline | 1988 |
The effects of chronic antidepressant treatment in an animal model of anxiety.
Topics: Amitriptyline; Animals; Antidepressive Agents; Anxiety; Desipramine; Diazepam; Disease Models, Animal; Flumazenil; Male; Rats; Time Factors | 1988 |
Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome.
Topics: Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Male; Nortriptyline; Psychiatric Status Rating Scales | 1985 |
Desipramine subsensitizes nicotinic mechanism involved in regulating core temperature.
Topics: Amitriptyline; Animals; Body Temperature Regulation; Brain; Desipramine; Fluoxetine; Light; Lithium; Male; Nicotine; Phenelzine; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1988 |
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine | 1988 |
Calmodulin inhibitors induce wallerian degeneration of mammalian peripheral nerves.
Topics: Amitriptyline; Animals; Calmodulin; Desipramine; Female; Male; Nerve Degeneration; Rats; Rats, Inbred Strains; Sciatic Nerve; Wallerian Degeneration | 1988 |
Quantitative homogeneous enzyme immunoassays for amitriptyline, nortriptyline, imipramine, and desipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Cross Reactions; Desipramine; Humans; Imipramine; Immunoenzyme Techniques; Methods; Nortriptyline | 1986 |
Two tricyclic antidepressant poisonings: levels of amitriptyline, nortriptyline and desipramine in post-mortem biological samples.
Topics: Adult; Amitriptyline; Chromatography, High Pressure Liquid; Desipramine; Humans; Male; Nortriptyline; Suicide; Verapamil | 1987 |
Effects of chronic amitriptyline and desipramine on food intake and body weight in rats.
Topics: Amitriptyline; Animals; Body Weight; Deoxyglucose; Desipramine; Feeding Behavior; Female; Infusion Pumps; Male; Motor Activity; Rats; Rats, Inbred Strains; Sucrose | 1987 |
Plasma-serum differences in the assessment of tricyclic antidepressant blood levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Nortriptyline; Plasma | 1987 |
Cardiovascular effects of polycyclic antidepressants.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depression; Desipramine; Doxepin; Female; Heart; Humans; Imipramine; Male; Middle Aged | 1986 |
Tricyclic antidepressant inhibition of the electrical evoked responses of the rat urinary bladder strip-effect of variation in extracellular Ca2+ concentration.
Topics: Amitriptyline; Animals; Atropine; Calcium; Desipramine; Drug Synergism; Electric Stimulation; Female; In Vitro Techniques; Male; Rats; Urinary Bladder | 1986 |
Tricyclic antidepressants antagonize prostaglandin (PG) E2-induced contractions of the guinea pig ileum and hypomotility in the mouse.
Topics: Acetylcholine; Amitriptyline; Animals; Desipramine; Dinoprostone; Guinea Pigs; Histamine Antagonists; Ileum; Male; Mice; Motor Activity; Muscle Contraction; Prostaglandins E | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Acute effects of antidepressants on hippocampal seizures.
Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hippocampus; Imipramine; Maprotiline; Propiophenones; Rats; Trazodone | 1985 |
Tricyclic antidepressant and metabolite levels in chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chromatography, Liquid; Depression; Desipramine; Female; Half-Life; Humans; Imipramine; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Nortriptyline; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis | 1985 |
Tolerance to therapeutic effects of antidepressants.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chronic Disease; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Imipramine; Middle Aged; Recurrence | 1985 |
Potentiation of morphine antinociception by monoamine reuptake inhibitors in the rat spinal cord.
Topics: 1-Naphthylamine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Drug Synergism; Male; Morphine; Nociceptors; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Sertraline; Spinal Cord | 1985 |
Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes.
Topics: Amitriptyline; Antipyrine; Desipramine; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Metoprolol; Microsomes, Liver; Theophylline | 1985 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhydramine; Disease Models, Animal; Electroshock; Ethanol; Humans; Imipramine; Male; Maprotiline; Mianserin; Mice; Motor Activity; Nialamide; Pargyline; Tranylcypromine | 1985 |
Acute response to methylphenidate as a predictor of outcome of treatment with TCAs in the elderly.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Emotions; Female; Humans; Male; Methylphenidate; Middle Aged; Norepinephrine; Outcome and Process Assessment, Health Care; Probability; Psychiatric Status Rating Scales; Serotonin | 1985 |
Tricyclic blood levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Humans | 1985 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
Metabolism of amitriptyline, nortriptyline, imipramine and desipramine to yield hydroxylamines.
Topics: Amitriptyline; Animals; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Guinea Pigs; Hydroxylamines; Imipramine; In Vitro Techniques; Mass Spectrometry; Microsomes, Liver; Mitochondria, Liver; Nortriptyline; Rabbits | 1973 |
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine | 1974 |
Effects of noradrenaline pump blockers on its uptake by synaptosomes from several brain regions; additional evidence for dopamine terminals in the frontal cortex.
Topics: Amitriptyline; Animals; Benztropine; Biological Transport, Active; Carbon Radioisotopes; Cerebral Cortex; Desipramine; Dibenzazepines; Dopamine; Frontal Lobe; Imipramine; Mice; Norepinephrine; Synaptosomes; Tritium | 1974 |
Toxicology of some autopsy cases involving tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Autopsy; Brain Chemistry; Desipramine; Dibenzazepines; Ethanol; Female; Humans; Imipramine; Kidney; Liver; Lung; Male; Middle Aged; Nortriptyline; Protein Binding; Spleen; Stomach | 1974 |
A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cats; Chlorpromazine; Desipramine; Electroencephalography; Electromyography; Evoked Potentials; Female; Imipramine; Male; Mesencephalon; Methamphetamine; Pargyline; Perphenazine; Reticular Formation; Seizures; Sleep; Wakefulness | 1969 |
Effects of antidepressant drugs on wakefulness and sleep in the cat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Chlorpromazine; Circadian Rhythm; Desipramine; Electromyography; Evoked Potentials; Female; Imipramine; Male; Mesencephalon; Methamphetamine; Pargyline; Perphenazine; Reticular Formation; Sleep; Sleep Stages; Time Factors; Wakefulness | 1969 |
Adhesion of human blood platelets to glass and polymer surfaces. I. Studies with platelets in plasma.
Topics: Adult; Age Factors; Amitriptyline; Aspirin; Blood Coagulation Disorders; Chloromercuribenzoates; Chlorpromazine; Citrates; Desipramine; Edetic Acid; Glass; Glucosamine; Heparin; Humans; Imipramine; Middle Aged; Platelet Adhesiveness; Polyethylenes; Polymers; Polytetrafluoroethylene; Polyvinyl Chloride; Promethazine; Sulfinpyrazone | 1974 |
Anti-inflammatory activity of imipramine and congeners.
Topics: Adenosine Triphosphatases; Alanine Transaminase; Amitriptyline; Animals; Arthritis; Aspartate Aminotransferases; Brain; Bronchial Spasm; Desipramine; Formaldehyde; Histamine; Hydrocortisone; Imipramine; Liver; Lysergic Acid Diethylamide; Phenylbutazone; Rats; Serotonin | 1966 |
[Protein binding of some psychoactive drugs with a tricyclic ring system, as a function of their chemical constitution].
Topics: Acepromazine; Alcohols; Amitriptyline; Chemical Phenomena; Chemistry, Physical; Chlorpromazine; Chromatography, Gel; Desipramine; Dialysis; Dibenzazepines; Dibenzocycloheptenes; Imipramine; Phenothiazines; Promazine; Protein Binding; Serum Albumin, Bovine; Thiazines; Triflupromazine | 1970 |
[Action of various tricyclic antidepressive agents on the estrous cycle of the female rat].
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dibenzazepines; Estrus; Female; Imipramine; Keratins; Opipramol; Pregnancy; Rats; Vaginal Diseases | 1970 |
Effects of some analgesics and antidepressants on the (Na + + K + )-adenosine triphosphatase from cortices of brain and kidney.
Topics: Adenosine Triphosphatases; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cattle; Cerebral Cortex; Chlorpromazine; Cyclazocine; Desipramine; Dose-Response Relationship, Drug; Hydralazine; Imipramine; In Vitro Techniques; Kidney; Kidney Cortex; Pentazocine; Phenazocine; Phenelzine; Potassium; Sodium; Tranylcypromine | 1972 |
Effects of pharmacological agents on the physiological responses of hair discs.
Topics: Acetylcholine; Action Potentials; Alkaloids; Amitriptyline; Animals; Anticonvulsants; Calcium; Catecholamines; Desipramine; Electric Stimulation; Hair; Imipramine; Lobeline; Magnesium; Monoamine Oxidase Inhibitors; Nicotine; Parasympathomimetics; Plants, Medicinal; Plants, Toxic; Potassium; Rats; Reserpine; Sensory Receptor Cells; Serotonin; Skin Physiological Phenomena; Synaptic Transmission; Touch; Veratrum | 1967 |
Systematic identification of psychotropic drugs by thin layer chromatography. II.
Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents | 1968 |
Interactions of tricyclic antidepressants and 5-hydroxyindolealkylamine precursors on spinal monosynaptic reflex transmission.
Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Amitriptyline; Animals; Antidepressive Agents; Cats; Desipramine; Drug Interactions; Drug Synergism; Imipramine; Reflex, Monosynaptic; Serotonin; Spinal Nerves; Synaptic Transmission; Time Factors | 1971 |
Stimulated formation of adenosine 3',5'-monophosphate by desipramine in brain slices.
Topics: Adenine; Adenosine Triphosphate; Amitriptyline; Animals; Brain; Carbon Isotopes; Chlorpromazine; Cyclic AMP; Desipramine; Guinea Pigs; Histamine; Imipramine; Male; Norepinephrine; Perphenazine; Phentolamine; Phosphoric Monoester Hydrolases; Propranolol; Rats; Rats, Inbred Strains; Theophylline; Tritium; Veratrine | 1971 |
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents | 1972 |
Effect of psychotropic drugs on phosphodiesterase and cyclic AMP level in rat brain in vivo.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlorpromazine; Chlorprothixene; Cyclic AMP; Desipramine; Haloperidol; Imipramine; Male; Phosphoric Diester Hydrolases; Rats; Theophylline; Tranquilizing Agents; Triflupromazine; Tritium | 1973 |
Influence of various substances which induce and inhibit aggregation on the uptake of deoxyglucose by human blood platelets.
Topics: Adenosine Diphosphate; Amitriptyline; Antidepressive Agents; Blood Glucose; Blood Platelets; Bucladesine; Carbon Radioisotopes; Chlorpromazine; Cyproheptadine; Desipramine; Epinephrine; Glucose; Humans; In Vitro Techniques; Norepinephrine; Nortriptyline; Platelet Adhesiveness; Promethazine; Serotonin; Thrombin | 1974 |
Lipid phase transitions and drug interactions.
Topics: Amitriptyline; Binding Sites; Calorimetry; Desipramine; Electron Spin Resonance Spectroscopy; Imipramine; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Morphinans; Morphine; Nortriptyline; Palmitic Acids; Phosphatidylcholines; Structure-Activity Relationship; Temperature; Thermodynamics | 1974 |
Antagonism to reserpine induced depression by imipramine, related psychoactive drugs, and some autonomic agents.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Behavior, Animal; Cyproheptadine; Desipramine; Diphenhydramine; Hallucinogens; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Mice; Promazine; Psychopharmacology; Reserpine; Serotonin | 1965 |
Anorexigenic drugs and lipid mobilisation.
Topics: Amitriptyline; Animals; Appetite Depressants; Chlorphentermine; Desipramine; Dextroamphetamine; Fatty Acids; Imipramine; Lipid Metabolism; Methylphenidate; Piperidines; Rats | 1965 |
In vivo inhibition of 3H-noradrenaline uptake by mouse brain slices in vitro.
Topics: Amitriptyline; Amphetamine; Animals; Brain; Chlordiazepoxide; Chlorpromazine; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Norepinephrine; Tritium | 1966 |
Ionization constants and water solubilities of some aminoalkylphenothiazine tranquillizers and related compounds.
Topics: Amitriptyline; Chemical Phenomena; Chemistry; Chlorpromazine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Solubility; Thioridazine; Tranquilizing Agents; Trifluoperazine; Water | 1967 |
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine | 1967 |
[Aggressiveness of the rat following combined treatment with monomaime oxidase inhibitors and other psychotropic drugs, especially thymoleptics].
Topics: Aggression; Alkaloids; Amitriptyline; Amphetamine; Animals; Anthracenes; Body Temperature; Central Nervous System; Desipramine; Dibenzazepines; Dihydroxyphenylalanine; Humans; Hydrazines; Imipramine; Indoles; Iproniazid; Isocarboxazid; Male; Nortriptyline; Opipramol; Pargyline; Phenelzine; Rats; Stimulation, Chemical; Tranylcypromine | 1969 |
The inhibition of human platelet 5-hydroxytryptamine uptake by tricyclic antidepressive drugs. The relation between structure and potency.
Topics: Amitriptyline; Blood Platelets; Desipramine; Dibenzazepines; Humans; Imipramine; In Vitro Techniques; Serotonin; Serotonin Antagonists | 1969 |
On the mechanism of 5-hydroxytryptamine release by thymoleptics.
Topics: Amitriptyline; Animals; Body Temperature Regulation; Cerebral Cortex; Desipramine; Dibenzazepines; Female; Glucose; Imipramine; Nialamide; Oxygen Consumption; Rabbits; Serotonin; Stimulation, Chemical | 1969 |
Assessment of anti-reserpine and anti-apomorphine activities of some psychic energizers in pigeons.
Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Columbidae; Deanol; Desipramine; Female; Hydrazines; Imipramine; Male; Opipramol; Orphenadrine; Reserpine; Vomiting | 1969 |
The effects of some centrally acting drugs on the glucocorticoid induction of hepatic tyrosine transaminase.
Topics: Adrenalectomy; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Desipramine; Diphenhydramine; Enzyme Induction; Female; Fluocinolone Acetonide; Fluorometholone; Glucocorticoids; Hydrocortisone; Imipramine; Liver; Male; Prednisone; Proadifen; Promazine; Promethazine; Rats; Reserpine; Sex Factors; Triflupromazine; Tyrosine Transaminase | 1969 |
Effect of antidepressant drugs on accumulation and disappearance of monoamines formed in vivo from labelled precursors in mouse brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Carbon Isotopes; Desipramine; Dopamine; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Serotonin; Tritium; Tryptophan; Tyrosine | 1970 |
Modification by a tricyclic series of compounds of the noradrenaline effect on the cat nictitating membrane.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Desipramine; Dibenzazepines; Drug Synergism; Imipramine; Nictitating Membrane; Norepinephrine; Nortriptyline | 1971 |
The effect of imipramine-like drugs and antihistamine drugs on uptake mechanisms in the central noradrenaline and 5-hydroxytryptamine neurons.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Brompheniramine; Chlorpheniramine; Desipramine; Dibenzazepines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Imipramine; Male; Microscopy, Fluorescence; Monoamine Oxidase Inhibitors; Neurons; Nialamide; Norepinephrine; Rats; Reflex; Reserpine; Serotonin | 1971 |
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
Topics: Amitriptyline; Animals; Carbon Isotopes; Carbon Monoxide; Chlorpromazine; Cyclic N-Oxides; Cytochromes; Dealkylation; Desipramine; Horses; Imipramine; Kinetics; Liver; Male; NADP; Organ Specificity; Oxidation-Reduction; Proadifen; Rats; Species Specificity; Subcellular Fractions; Swine; Tetrazolium Salts | 1972 |
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine | 1972 |
Effect of dimethyl and monomethyl tricyclic antidepressants on central 5-hydroxytryptamine processes in the frog.
Topics: Amitriptyline; Animals; Antidepressive Agents; Anura; Brain; Desipramine; Dibenzazepines; Imipramine; Male; Muscle Contraction; Nortriptyline; Rana temporaria; Serotonin | 1971 |
[Tricyclic anti-depressant drugs and dopamine sensitive adenylcyclase from rat caudate nuclei].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amitriptyline; Animals; Antidepressive Agents; Basal Metabolism; Caudate Nucleus; Chlorpromazine; Desipramine; Dopamine; Imipramine; Nortriptyline; Rats; Stimulation, Chemical | 1974 |
Relationships between tricyclic antidepressant concentrations, 1-3H-noradrenaline uptake and chronotropic effect in isolated rat atria.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Radioisotopes; Chromatography, Thin Layer; Clomipramine; Dealkylation; Desipramine; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Female; Heart Atria; Heart Rate; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors; Tritium | 1974 |
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood Pressure; Depression; Desipramine; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Motor Activity; Nortriptyline; Pulse; Time Factors; Triiodothyronine; Verbal Behavior | 1974 |
The "on-off" side effect of L-DOPA.
Topics: Age Factors; Amitriptyline; Aromatic Amino Acid Decarboxylase Inhibitors; Athetosis; Carbidopa; Catechol O-Methyltransferase Inhibitors; Chlordiazepoxide; Chorea; Desipramine; Diazepam; Dietary Proteins; Enzyme Inhibitors; Female; Humans; Imipramine; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Physical Exertion; Picolinic Acids; Prochlorperazine; Sex Factors; Stress, Psychological | 1974 |
Serious side effects from routine doses of non-Mao inhibitor antidepressants. How "well" is well tolerated?
Topics: Adult; Amitriptyline; Antidepressive Agents; Desipramine; Drug Tolerance; Female; Humans; Imipramine; Male; Middle Aged | 1973 |
Cardiac effects of antidepressants.
Topics: Amitriptyline; Animals; Anti-Arrhythmia Agents; Antidepressive Agents; Coronary Circulation; Depression, Chemical; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Dimethylamines; Electrocardiography; Female; Guinea Pigs; Heart; Heart Conduction System; Imipramine; In Vitro Techniques; Male; Oximes; Rats; Vasopressins | 1972 |
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature | 1974 |
Functional group contribution in ion-pair extraction of tricyclic amines.
Topics: Amitriptyline; Bromides; Chemical Phenomena; Chemistry; Chlorates; Chlorides; Desipramine; Imipramine; Iodides; Ions; Mathematics; Naphthalenes; Nitrates; Nortriptyline; Spectrophotometry, Ultraviolet; Tosyl Compounds | 1972 |
[Innervation of efferent seminal ducts in man: site of action and effects of psychotropic drugs].
Topics: Affective Symptoms; Amitriptyline; Desipramine; Humans; Imipramine; Infertility, Male; Male; Norepinephrine; Serotonin; Vas Deferens | 1972 |
Proceedings: Effect of tricyclic antidepressants on drug metabolism.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Hexobarbital; Humans; Imipramine; Liver; Male; Nortriptyline; Rats | 1972 |
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents | 1972 |
Binding of cyproheptadine-(N-methyl- 14 C) by human blood platelets: inhibition by phenothiazines and tricyclic antidepressants.
Topics: Amitriptyline; Blood Platelets; Carbon Isotopes; Centrifugation; Chlorpromazine; Cyproheptadine; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phenothiazines; Platelet Adhesiveness; Promethazine | 1973 |
Interaction of Ro 4-1284 with doxepin, amitriptyline and desmethylimipramine on mouse avoidance behavior.
Topics: Amitriptyline; Animals; Avoidance Learning; Desipramine; Dibenzoxepins; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Male; Mice; Quinolizines; Reserpine; Time Factors | 1973 |
Studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
Topics: Adult; Amitriptyline; Antidepressive Agents; Charcoal; Chromatography, Gas; Desipramine; Female; Gastric Juice; Humans; Imipramine; Male; Mass Spectrometry; Nortriptyline; Poisoning | 1973 |
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine.
Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium | 1973 |
The interference of tricyclic antidepressants with the central hypotensive effect of clonidine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Cats; Clonidine; Desipramine; Imipramine; Time Factors | 1973 |
[Evaluation of central antireserpine effect by the use of light blink reflex (author's transl)].
Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Diethylamines; Dimethylamines; Ethylenediamines; Glycolates; Imipramine; Light; Nortriptyline; Propylamines; Rabbits; Reflex; Reserpine | 1973 |
Stimulation of drug metabolism in man by tricyclic antidepressants.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Amitriptyline; Amobarbital; Analysis of Variance; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Humans; Hydrocortisone; Hydroxycorticosteroids; Imipramine; Male; Nortriptyline; Stimulation, Chemical; Time Factors | 1973 |
The effect of p-chloroamphetamine on motility in rats after inhibition of monoamine synthesis, storage, uptake and receptor interaction.
Topics: Amitriptyline; Amphetamine; Animals; Biogenic Amines; Catecholamines; Chlorine; Chlorpheniramine; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Female; Haloperidol; Imipramine; Methyltyrosines; Motor Activity; Rats; Receptors, Cholinergic; Serotonin Antagonists; Spiro Compounds; Time Factors | 1974 |
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors | 1974 |
Treatment of the depressed outpatient.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Child; Chlordiazepoxide; Depression; Desipramine; Diazepam; Humans; Hydroxyzine; Imipramine; Lithium; Methylphenidate; Outpatient Clinics, Hospital; Suicide; Tranylcypromine | 1974 |
[Effect of thymoleptica in the drawing test].
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Female; Humans; Imipramine; Middle Aged; Personality Disorders; Projective Techniques; Psychological Tests | 1967 |
Further studies on the effect of various drugs on the uptake of tyramine-3H and formation of octopamine-3H in the rat heart.
Topics: Amitriptyline; Animals; Cocaine; Desipramine; Diphenhydramine; Female; Glucosyltransferases; Methylphenidate; Myocardium; Neurons; Norepinephrine; Octopamine; Pyridines; Rats; Sympathetic Nervous System; Triprolidine; Tritium; Tyramine | 1969 |
Pharmacological studies of 5-methyl-8-ethyl-sulfonyl-10-(2-dimethylaminoethyl)-5H-dibenzo (B,E) (1,4) diazepine-11 (10)-one (SM-307), an antidepressive substance.
Topics: Amitriptyline; Animals; Antidepressive Agents; Barbiturates; Behavior, Animal; Body Temperature; Cats; Desipramine; Dibenzazepines; Dopamine; Epinephrine; Haplorhini; Ileum; Imipramine; In Vitro Techniques; Male; Mice; Monoamine Oxidase; Muscle, Smooth; Norepinephrine; Rats; Reserpine; Respiration | 1971 |
Blocking H 3 -Norepinephrine uptake and some guanethidine-induced effects with tricyclic psychotherapeutic drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Autonomic Fibers, Postganglionic; Benzofurans; Blood Pressure; Cats; Chlorpromazine; Desipramine; Dibenzoxepins; Electric Stimulation; Guanethidine; Heart; Imipramine; Male; Methylamines; Myocardium; Nictitating Membrane; Norepinephrine; Rats; Rats, Inbred Strains; Thioridazine; Tranquilizing Agents; Tritium | 1972 |
Fluorimetric determinations by ion pair extraction. 3. Extraction constants of ion pairs between anthracene-2-sulphonate and mono- and divalent amines.
Topics: Amines; Amitriptyline; Anthracenes; Desipramine; Dibenzazepines; Emetine; Hydrocarbons, Halogenated; Imipramine; Ions; Nortriptyline; Prenylamine; Spectrometry, Fluorescence; Sulfonic Acids | 1972 |
Toxic interactions of d-amphetamine and tricyclic antidepressants in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Antagonism; Drug Interactions; Drug Synergism; Imipramine; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nortriptyline; Promazine; Time Factors | 1972 |
[Effect of the tricyclic antidepressants--imizin, desipramine, amitryptyline and azaphen on gastric secretion in rats].
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Gastric Juice; Gastric Mucosa; Imipramine; Male; Oxazines; Piperazines; Pyrimidines; Rats; Stomach | 1972 |
Rophe neurons: effect of tricyclic antidepressant drugs.
Topics: Action Potentials; Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dibenzazepines; Imipramine; Male; Mesencephalon; Nerve Endings; Phenylalanine; Rats; Serotonin | 1972 |
Interaction between digoxin and tricyclic antidepressants in the rat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Heart; Heart Arrest; Imipramine; Male; Nortriptyline; Rats; Reserpine; Stress, Physiological | 1972 |
A quantitative study of the anticholinergic action of several tricyclic antidepressants on the rat isolated fundal strip.
Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Dibenzocycloheptenes; Dimethylamines; Female; In Vitro Techniques; Mathematics; Muscle Contraction; Opipramol; Parasympatholytics; Rats; Stomach | 1972 |
[New drugs. 6].
Topics: Amitriptyline; Cycloheptanes; Desipramine; Phenothiazines; Tranquilizing Agents | 1971 |
[Stereotypy following amphetamine and apomorphine and its influencing by drugs].
Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Behavior, Animal; Desipramine; Drug Synergism; Female; Imipramine; Mastication; Mice; Rats; Tranquilizing Agents | 1971 |
Detection of some psychotherapeutic drugs and their metabolites in urine.
Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1971 |
Antidepressant overdosage in children--a new menace.
Topics: Accidents, Home; Adolescent; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Child; Child, Preschool; Desipramine; Drug Compounding; Drug Packaging; Humans; Imipramine; Infant; Seizures | 1971 |
[Cenesthetic schizophrenia as a significant type in schizophrenic diseases].
Topics: Adult; Affective Symptoms; Amitriptyline; Brain Stem; Desipramine; Diagnosis, Differential; Electroencephalography; Female; Humans; Male; Neurotic Disorders; Personality Disorders; Pneumoencephalography; Prognosis; Schizophrenia; Schizotypal Personality Disorder; Sex Factors; Thioridazine | 1971 |
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine | 1971 |
[Changes in tonus of the bladder and its sphincter under thymoleptic treatment. Cystomanometric measurements in man].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Carbachol; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Manometry; Middle Aged; Muscle Tonus; Nortriptyline; Pressure; Urinary Bladder; Water-Electrolyte Balance | 1971 |
Central effects of 6-hydroxydopamine.
Topics: Amantadine; Amitriptyline; Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Desipramine; Dopamine; Electroencephalography; Female; Humans; Hydroxydopamines; Imipramine; Male; Mice; Motor Activity; Norepinephrine; Rats; Seizures; Species Specificity; Stereotyped Behavior | 1971 |
[Differential therapeutic experiments with antidepressive efficacious psychopharmacotics].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Humans; Imipramine; Psychopharmacology; Thioridazine | 1967 |
Central muscle relaxant activity of imipramine, amitriptyline and desmethylimipramine.
Topics: Amitriptyline; Animals; Cats; Central Nervous System; Desipramine; Female; Imipramine; Male; Muscles | 1966 |
Further evidence of central muscle relaxant activity of imipramine, desmethylimipramine and amitriptyline.
Topics: Amitriptyline; Animals; Behavior, Animal; Blood Pressure; Cats; Desipramine; Female; Imipramine; Male; Mephenesin; Muscle Contraction; Muscles; Rabbits; Reflex | 1966 |
Effect of psychotherapeutic drugs on hyperemotionality of rats in which the olfactory bulb was removed.
Topics: Amitriptyline; Animals; Benperidol; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Desipramine; Emotions; Imipramine; Limbic System; Male; Meprobamate; Phenobarbital; Rats; Reserpine; Tranquilizing Agents | 1967 |
Plasma protein binding of tricyclic anti-depressants in man.
Topics: Amitriptyline; Antidepressive Agents; Blood Proteins; Carbon Isotopes; Desipramine; Humans; Imipramine; Nortriptyline; Phenytoin; Protein Binding; Temperature; Tritium | 1969 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology | 1969 |
Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antimetabolites; Brain; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Nortriptyline; Reserpine; Serotonin; Tritium; Tryptamines | 1969 |
Effects of tricyclic antidepressants on the uptake and mabolism of intracisternally administered norepinephrine-H3 in rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Brain Chemistry; Cell Membrane; Cerebral Ventricles; Desipramine; Imipramine; Injections; Injections, Intraperitoneal; Male; Mitochondria; Norepinephrine; Normetanephrine; Nortriptyline; Rats; Tritium | 1969 |
An in vitro study of the effects of tricyclic antidepressant drugs on the accumulation of C14-serotonin by rabbit brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Stem; Carbon Isotopes; Desipramine; Imipramine; In Vitro Techniques; Rabbits; Serotonin; Serotonin Antagonists | 1969 |
Use of antidepressant drugs during the first trimester.
Topics: Amitriptyline; Desipramine; Embryo, Mammalian; Female; Gestational Age; Humans; Imipramine; Nortriptyline; Pregnancy | 1969 |
Thin-layer chromatography of ion pairs on impregnated layers.
Topics: Alkaloids; Amitriptyline; Atropine; Chromatography, Thin Layer; Desipramine; Imipramine; Ions; Scopolamine | 1969 |
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine | 1969 |
[Effect of thymoleptics on acid production of the stomach. Preliminary report].
Topics: Amitriptyline; Chlorpromazine; Depression; Depression, Chemical; Desipramine; Dibenzazepines; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Humans; Imipramine; Methotrimeprazine; Stomach; Tranquilizing Agents | 1969 |
[Cardiodepressive and local anesthetic effect of thymoleptics. Comparative studies with imipramine, desipramine, amitriptyline, nortriptyline and melitracene].
Topics: Amitriptyline; Anesthetics, Local; Animals; Anthracenes; Cornea; Depression, Chemical; Desipramine; Drug Synergism; Guinea Pigs; Heart Rate; Imipramine; In Vitro Techniques; Norepinephrine; Nortriptyline; Rabbits; Time Factors; Tyramine | 1969 |
[Thymoleptics and lipolysis].
Topics: Adipose Tissue; Amitriptyline; Animals; Antidepressive Agents; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Fatty Acids, Nonesterified; Imipramine; In Vitro Techniques; Lipid Metabolism; Male; Norepinephrine; Nortriptyline; Photometry; Rats; Stimulation, Chemical; Tranquilizing Agents | 1969 |
Blockade of norepinephrine uptake and other activities of 5-(3'-dimethylaminopropyl)-dibenzo(a,d) (1,4)cycloheptadiene hydrochloride (AY-8794) and structurally related compounds.
Topics: Adipose Tissue; Amitriptyline; Animals; Anti-Inflammatory Agents; Biological Transport; Carrageenan; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Edema; Epididymis; Fatty Acids, Nonesterified; Female; Gastric Juice; Heart; Hindlimb; Imipramine; Injections, Intraperitoneal; Lipid Mobilization; Male; Mathematics; Mice; Myocardium; Norepinephrine; Rats; Time Factors; Tritium | 1969 |
Removal of 5-hydroxytryptamine by rat isolated lung.
Topics: Amitriptyline; Animals; Desipramine; Hydrazines; In Vitro Techniques; Iproniazid; Lung; Methysergide; Monoamine Oxidase Inhibitors; Rats; Reserpine; Serotonin; Stomach; Tritium | 1970 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine | 1970 |
[Clinical antidepressant drug therapy].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Nortriptyline; Prognosis | 1970 |
Effects of psychotherapeutic drugs on hypothalamic- induced hissing in cats.
Topics: Amitriptyline; Animals; Cats; Chlordiazepoxide; Chlorpromazine; Desipramine; Electric Stimulation; Female; Hypothalamus; Imipramine; Injections, Intraperitoneal; Male; Pentobarbital; Perphenazine; Tranquilizing Agents; Trifluoperazine; Vocalization, Animal | 1970 |
Removal of 5-hydroxytryptamine in the pulmonary circulation of rat isolated lungs.
Topics: Amitriptyline; Animals; Capillaries; Depression, Chemical; Desipramine | 1970 |
Antianxiety and anti-depressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Depression; Desipramine; Dibenzoxepins; Humans; Imipramine; Nortriptyline; Tranquilizing Agents | 1970 |
[Intragastric telemetric pH measuring during thymoleptic therapy].
Topics: Amitriptyline; Depression; Depression, Chemical; Desipramine; Dibenzazepines; Female; Gastric Acidity Determination; Humans; Hydrogen-Ion Concentration; Imipramine; Male; Neurasthenia; Stimulation, Chemical; Telemetry; Tranquilizing Agents | 1970 |
[Animal experiments to study the cardiotoxic effect of thymoleptics].
Topics: Amitriptyline; Animals; Blood Pressure; Cats; Desipramine; Drug Synergism; Epinephrine; Heart; Heart Failure; Humans; Imipramine; Nortriptyline; Tranquilizing Agents | 1971 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug Synergism; Female; Fever; Humans; Hypertension; Hypotension; Imipramine; Isocarboxazid; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Seizures | 1971 |
Comparative study of imipramine, amitriptyline and their desmethyl analogues in the hypothyroid rat.
Topics: Amitriptyline; Animals; Blepharoptosis; Desipramine; Exploratory Behavior; Female; Hypothyroidism; Imipramine; Motor Activity; Nortriptyline; Posture; Propylthiouracil; Psychopharmacology; Rats; Sympathomimetics; Tetrabenazine | 1967 |
Mechanism of inhibition of experimental inflammation by antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carrageenan; Catecholamines; Desipramine; Dextrans; Drug Synergism; Edema; Female; Formaldehyde; Imipramine; Nortriptyline; Rats | 1967 |
[On the management of pain using antidepressive agents].
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Nortriptyline; Pain | 1967 |
[Nortriptyline poisoning].
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Imipramine; Nortriptyline | 1967 |
Inhibition by drugs of the accumulation in vitro of 5-hydroxytryptamine in guinea-pig vas deferens.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Guinea Pigs; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Male; Serotonin; Vas Deferens | 1968 |
Tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Nortriptyline; Opipramol | 1968 |
The effect of various drug pretreatments on amine-induced phosphorylase activation and amine uptake.
Topics: Amitriptyline; Animals; Carbon Isotopes; Depression, Chemical; Desipramine; Diphenhydramine; Drug Synergism; Female; Glucosyltransferases; Heart; Imipramine; Isoproterenol; Methylphenidate; Myocardium; Norepinephrine; Promethazine; Propranolol; Rats; Stimulation, Chemical; Tranylcypromine; Triprolidine; Tritium; Tyramine | 1968 |
A new type of drug enhancement: increased maximum response to cumulative noradrenaline in the isolated rat vas deferens.
Topics: Amitriptyline; Animals; Cocaine; Desipramine; Drug Synergism; Imipramine; Male; Muscle Contraction; Norepinephrine; Phentolamine; Rats; Vas Deferens | 1968 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents | 1968 |
[On the analgesic affect of thymoleptics].
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Codeine; Desipramine; Dibenzazepines; Humans; Imipramine; Male; Mice; Nortriptyline; Phosphates; Quinones; Tranquilizing Agents | 1968 |
[Investigation of gastric ulcer inhibiting and secreto-inhibitory actions of thymoleptics in rats].
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Gastric Juice; Imipramine; Nortriptyline; Rats; Stomach Ulcer | 1968 |
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1968 |
Cataleptic state and hypothermia in mice, caused by central cholinergic stimulation and antagonized by anticholinergic and antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Catalepsy; Desipramine; Hexamethonium Compounds; Humans; Hypothermia; Imipramine; Male; Mice; Nicotine; Nicotinic Acids; Nitrophenols; Parasympatholytics; Parasympathomimetics; Phosphoric Acids; Pilocarpine; Pralidoxime Compounds; Scopolamine; Tremorine | 1968 |
Clinical significance of anticholinergic effects of imipramine-like drugs.
Topics: Amitriptyline; Animals; Atropine; Columbidae; Depression; Desipramine; Diphenhydramine; Humans; Imipramine; Parasympatholytics; Scopolamine | 1969 |
Aryl-substituted triazines with antidepressant activity.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Synergism; Electroshock; Hexobarbital; Imipramine; Mice; Reserpine; Sleep; Triazines | 1969 |
Some observations on the adrenergic blocking activity of desipramine and amitriptyline on aortic strips of rabbits.
Topics: Amitriptyline; Animals; Aorta; Calcium; Chlorpromazine; Desipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rabbits; Receptors, Drug | 1969 |
Cardiac abnormalities in poisoning with tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Desipramine; Electrocardiography; Female; Heart; Humans; Imipramine; Nortriptyline | 1969 |
[The influence of psychopharmacologic agents on the acitvity of retinal neurons].
Topics: Action Potentials; Amitriptyline; Animals; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Neurons; Optic Nerve; Retina; Tranquilizing Agents | 1969 |
[The influence of psychopharmacologic agents on visual evoked potentials in the cat].
Topics: Amitriptyline; Animals; Cats; Cerebral Cortex; Chlorpromazine; Chlorprothixene; Desipramine; Diazepam; Evoked Potentials; Haloperidol; Tranquilizing Agents; Vision, Ocular; Visual Cortex | 1969 |
Desipramine.
Topics: Amitriptyline; Depression; Desipramine; Humans; Nortriptyline | 1965 |
Association between biochemical and behavioral actions of tricyclic antidepressants.
Topics: Amitriptyline; Animals; Behavior, Animal; Brain Chemistry; Desipramine; Female; Metaraminol; Myocardium; Neurons; Rats; Sympathetic Nervous System; Tetrabenazine | 1966 |
Effect of amitriptyline and related drugs on neuromuscular transmission.
Topics: Amitriptyline; Animals; Anura; Cats; Desipramine; Diaphragm; Imipramine; In Vitro Techniques; Neostigmine; Neuromuscular Junction; Phrenic Nerve; Rats; Sciatic Nerve | 1966 |
[Amnesic action of some anti-depressive drugs and their effect on cerebral acetylcholine in the rat].
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Desipramine; Imipramine; Memory; Rats; Scopolamine | 1966 |
[Psychopathological complications in antidepressant medication].
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Delirium; Depression; Desipramine; Dogs; Guinea Pigs; Humans; Imipramine; Mice; Movement; Rats; Tetrabenazine | 1966 |
[Amplification of the norepinephrine effect in man by psychopharmaca].
Topics: Amitriptyline; Blood Pressure; Desipramine; Electrocardiography; Electroencephalography; Humans; Imipramine; Isocarboxazid; Monoamine Oxidase Inhibitors; Norepinephrine; Thioridazine | 1966 |
[Therapeutic experiences in 5 clinics with a dibenzoxepine derivative in depressive states].
Topics: Amitriptyline; Depression; Desipramine; Dibenzothiepins; Dibenzoxepins; Humans; Imipramine; Monoamine Oxidase Inhibitors; Opipramol; Switzerland; Trimeprazine | 1966 |
[Comparative clinical experiences with Protriptyline in depressive conditions of various origins].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Nortriptyline; Opipramol | 1966 |
[Restraining action of antidepressive agents of the imipramine group on the cardiovascular centers].
Topics: Action Potentials; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Cats; Desipramine; Hypertension; Hypothalamus; Imipramine; Medulla Oblongata; Mesencephalon; Nictitating Membrane; Nortriptyline; Rats; Sciatic Nerve; Splanchnic Nerves | 1967 |
Central anticholinergic activity of imipramine and allied drugs.
Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Female; Imipramine; Male; Mice; Parasympatholytics; Seizures | 1967 |
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds.
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Imipramine; Male; Nortriptyline | 1967 |
[Clinical studies of a new antidepressive agent, nortriptyline].
Topics: Adolescent; Adult; Aged; Amitriptyline; Depression; Desipramine; Humans; Imipramine; Middle Aged; Neurotic Disorders; Nortriptyline | 1967 |
Chronic antidepressants and GABA "B" receptors: a GABA hypothesis of antidepressant drug action.
Topics: Amitriptyline; Animals; Antidepressive Agents; Citalopram; Desipramine; Frontal Lobe; gamma-Aminobutyric Acid; Hippocampus; Male; Nipecotic Acids; Pargyline; Proline; Propylamines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Viloxazine | 1984 |
Dexamethasone suppression test identifies subtypes of depression which respond to different antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Depression, Chemical; Desipramine; Dexamethasone; Diagnosis, Differential; Female; Humans; Imipramine; Male; Pituitary-Adrenal System | 1980 |
Affinity of butriptyline and other tricyclic antidepressants for alpha-adrenoceptor binding sites in rat brain.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Binding, Competitive; Brain; Desipramine; Dibenzocycloheptenes; Imipramine; In Vitro Techniques; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Suppression of histamine-induced adrenocorticotropic hormone release by antihistamines and antidepressants.
Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents; Desipramine; Diazepam; Doxepin; Histamine; Histamine H1 Antagonists; Imipramine; Iprindole; Male; Mianserin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Histamine; Stimulation, Chemical | 1982 |
Rapid down-regulation of serotonin2 receptor binding during combined administration of tricyclic antidepressant drugs and alpha 2 antagonists.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Desipramine; Kinetics; Male; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1983 |
Effects of phenothiazines and dibenzazepines on axonal transport and microtubule assembly in vitro.
Topics: Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Chlorpromazine; Desipramine; Dibenzazepines; Lofepramine; Microtubules; Phenothiazines; Phosphocreatine; Rana pipiens; Rana temporaria; Sciatic Nerve; Thioridazine; Trifluoperazine | 1982 |
Interaction of EEG sleep, antidepressants, and affective disease.
Topics: Amitriptyline; Antidepressive Agents; Brompheniramine; Depressive Disorder; Desipramine; Electroencephalography; Humans; Sleep; Sleep, REM; Zimeldine | 1982 |
Effects of amitriptyline, desipramine and zimeldine, alone and in combination with ethanol, on information processing and memory in healthy volunteers.
Topics: Adult; Amitriptyline; Cognition; Desipramine; Drug Interactions; Ethanol; Humans; Male; Memory; Psychomotor Performance; Zimeldine | 1983 |
Effects of antidepressants on skilled performance.
Topics: Adult; Amitriptyline; Antidepressive Agents; Breath Tests; Desipramine; Ethanol; Humans; Kinetics; Male; Posture; Psychomotor Performance; Reaction Time; Zimeldine | 1984 |
Interactions of tricyclic antidepressants with a synaptic ion channel.
Topics: Acetylcholine; Amitriptyline; Amphibian Venoms; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Desipramine; Electric Organ; Fishes; Imipramine; Ion Channels; Nortriptyline; Phencyclidine; Receptors, Nicotinic | 1981 |
Interaction of desipramine and amitriptyline with adrenergic mechanisms in the human iris in vivo.
Topics: Adult; Amitriptyline; Desipramine; Drug Interactions; Female; Humans; Male; Methoxamine; Middle Aged; Mydriatics; Norepinephrine; Pupil; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1981 |
Pre- and postsynaptic adrenergic activation by norepinephrine reuptake inhibitors in the field-stimulated rat vas deferens.
Topics: Amitriptyline; Animals; Chlorpromazine; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Male; Norepinephrine; Prazosin; Protriptyline; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1981 |
Alpha 2-adrenoreceptors on human platelets: selective labelling by [3H]clonidine and [3H]yohimbine and competitive inhibition by antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Binding, Competitive; Blood Platelets; Cell Membrane; Clonidine; Desipramine; Humans; In Vitro Techniques; Iprindole; Kinetics; Male; Mianserin; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Yohimbine | 1981 |
Lack of effect of raphe lesions on serotonin S2 receptor changes induced by amitriptyline and desmethylimipramine.
Topics: Amitriptyline; Animals; Brain Stem; Cerebral Cortex; Corpus Striatum; Desipramine; Dopamine; Hypothalamus; Male; Mesencephalon; Mianserin; Norepinephrine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Synaptic Transmission | 1982 |
Chronic antidepressant treatment enhances agonist affinity of brain alpha 1-adrenoceptors.
Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Brain; Desipramine; Iprindole; Kinetics; Male; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thalamus | 1983 |
Functional supersensitivity of CNS alpha 1-adrenoceptors following chronic antidepressant treatment.
Topics: Amitriptyline; Animals; Antidepressive Agents; Binding Sites; Desipramine; Hydroxydopamines; Iprindole; Male; Norepinephrine; Oxidopamine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reflex, Acoustic | 1983 |
The effects of acute and repeated administration of various antidepressant drugs on clonidine-induced hypoactivity in mice and rats.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Desipramine; Male; Mianserin; Mice; Mice, Inbred C57BL; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1983 |
Effects of amitriptyline, desipramine and mianserin on noradrenergic transmission in the rat isolated right ventricle.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Electric Stimulation; Heart; In Vitro Techniques; Male; Mianserin; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Synaptic Transmission; Yohimbine | 1983 |
Comparison of pharmacological treatment response between situational and non-situational depressions.
Topics: Amitriptyline; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Life Change Events; Lithium; Lithium Carbonate; Male; Time Factors | 1984 |
A study of the effects of clonidine on the EEG in rats treated with single and multiple doses of antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clonidine; Desipramine; Electroencephalography; Male; Mianserin; Rats; Rats, Inbred Strains | 1984 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine | 1984 |
The nonlinear kinetics of desipramine and 2-hydroxydesipramine in plasma.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Chromatography, High Pressure Liquid; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Middle Aged; Nortriptyline; Random Allocation | 1984 |
Manic symptoms following addition of lithium to antidepressant treatment.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged | 1984 |
Blood collection tubes for tricyclic antidepressant drugs: a reevaluation.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Preservation; Blood Proteins; Blood Specimen Collection; Desipramine; Humans; Imipramine; Nortriptyline; Plasma | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
Topics: Aggression; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorpromazine; Clomipramine; Desipramine; Diazepam; Humans; Injections; Male; Microinjections; Olfactory Bulb; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Use of an MMPI scale to predict antidepressant response to lithium.
Topics: Adult; Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Humans; Lithium; Male; MMPI; Prognosis | 1983 |
Spinal 5-HT or NA uptake inhibition potentiates supraspinal morphine antinociception in rats.
Topics: Amitriptyline; Animals; Central Nervous System; Citalopram; Desipramine; Drug Synergism; Injections, Intraventricular; Male; Morphine; Neural Pathways; Norepinephrine; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord | 1984 |
Facial EMG activity levels predict treatment outcome in depression.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyography; Facial Expression; Facial Muscles; Female; Humans; Imipramine; Maprotiline; Middle Aged; Muscle Contraction; Prognosis; Psychiatric Status Rating Scales | 1984 |
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists | 1984 |
Phenytoin: similarity to tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlordiazepoxide; Conditioning, Operant; Cues; Desipramine; Discrimination Learning; Imipramine; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1983 |
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline | 1983 |
Discriminative stimulus control with imipramine: transfer to other anti-depressants.
Topics: Amitriptyline; Animals; Behavior, Animal; Desipramine; Discrimination Learning; Imipramine; Male; Rats; Rats, Inbred Strains | 1983 |
Effects of a new antidepressant drug on active avoidance behavior in rats. Comparative study with tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Avoidance Learning; Desipramine; Extinction, Psychological; Female; Imipramine; Male; Piperazines; Rats | 1983 |
Massive eosinophilic reaction to desipramine in conjunction with pneumonia.
Topics: Aged; Amitriptyline; Bipolar Disorder; Desipramine; Dexamethasone; Eosinophilia; Female; Humans; Hydrocortisone; Leukocyte Count; Pneumonia | 1984 |
Therapeutic use of the tricyclic-induced switch in bipolar manic-depression.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Desipramine; Drug Therapy, Combination; Humans; Imipramine; Lithium; Lithium Carbonate; Male | 1982 |
The effect of repeated desipramine administration on water intake in rats.
Topics: Amitriptyline; Animals; Body Weight; Desipramine; Dose-Response Relationship, Drug; Drinking Behavior; Drug Tolerance; Male; Rats; Rats, Inbred Strains; Scopolamine; Time Factors | 1982 |
Somatic symptoms in depression and antidepressants.
Topics: Adult; Amitriptyline; Anxiety; Autonomic Nervous System Diseases; Constipation; Depressive Disorder; Desipramine; Erectile Dysfunction; Female; Humans; Male; Personality Inventory; Psychiatric Status Rating Scales; Xerostomia | 1983 |
Column deactivation in analysis for underivatized tricyclic antidepressants by gas chromatography with use of a nitrogen detector.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Humans; Imipramine; Nitrogen; Nortriptyline | 1983 |
Complex inhibition of [3H]imipramine binding by serotonin and nontricyclic serotonin uptake blockers.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1983 |
High-affinity uptake of [3H]norepinephrine by primary astrocyte cultures and its inhibition by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Animals, Newborn; Astrocytes; Biological Transport; Cells, Cultured; Desipramine; Dopamine; Kinetics; Norepinephrine; Rats | 1983 |
The methylphenidate test for differentiating desipramine-responsive from nortriptyline-responsive depression.
Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Desipramine; Emotions; Humans; Imipramine; Methylphenidate; Middle Aged; Norepinephrine; Nortriptyline | 1983 |
Tricyclic antidepressants and delirium.
Topics: Adolescent; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Black People; Delirium; Desipramine; Female; Hospitalization; Humans; Male; Middle Aged; Protriptyline | 1983 |
Age as a predictor of treatment response in endogenous depression.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans; Imipramine; Male; Middle Aged | 1983 |
Role of serotonin in the blockade of muricidal behavior by tricyclic antidepressants.
Topics: Aggression; Amitriptyline; Amphetamines; Animals; Desipramine; Diet; Humans; Imipramine; Male; Mice; p-Chloroamphetamine; Rats; Serotonin; Tryptophan | 1982 |
Pituitary-adrenal disinhibition in depression: marker of a subtype with characteristic clinical features and response to treatment?
Topics: Adult; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Pituitary-Adrenal System; Recurrence | 1981 |
Differential effect of chronic desipramine and amitriptyline treatment on rat brain adrenergic and serotonergic receptors.
Topics: Amitriptyline; Animals; Brain; Cerebral Cortex; Clonidine; Desipramine; Dihydroalprenolol; Dioxanes; Male; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Spiperone | 1981 |
Tricyclic antidepressants do not alter thyroid hormone levels in patients suffering from a major affective disorder.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Thyroid Hormones; Thyroxine; Triiodothyronine | 1981 |
Depression, antidepressants, and plasma DBH.
Topics: Adult; Amitriptyline; Depressive Disorder; Desipramine; Dopamine beta-Hydroxylase; Female; Humans; Male; Psychiatric Status Rating Scales | 1981 |
Failure of chronic antidepressant treatment to alter growth hormone response to clonidine.
Topics: Amitriptyline; Clonidine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Growth Hormone; Humans; Male; Middle Aged | 1982 |
True and pseudo cholinesterases in depression.
Topics: Acetylcholinesterase; Adult; Amitriptyline; Anxiety; Butyrylcholinesterase; Cholinesterases; Depressive Disorder; Desipramine; Erythrocytes; Female; Humans; Male; Middle Aged | 1982 |
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Thyroxine; Triiodothyronine | 1982 |
Plasma concentrations of tricyclic antidepressants in clinical practice.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Nortriptyline | 1982 |
Tricyclic antidepressant plasma levels: the state of the art and clinical prospects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Imipramine; Nortriptyline | 1982 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Protriptyline | 1982 |
Bonded-phase extraction of plasma tricyclic antidepressant drugs for gas chromatographic analysis.
Topics: Acetates; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Desipramine; Humans; Imipramine; Methods; Nortriptyline | 1982 |
The relationship of therapeutic response to antidepressant plasma levels: an update.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive Disorder; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Patient Compliance; Protriptyline | 1982 |
Evidence for in vivo methylation of the secondary amino antidepressant desipramine to imipramine in humans.
Topics: Amitriptyline; Biotransformation; Depressive Disorder; Desipramine; Humans; Imipramine; Methylation; Nortriptyline | 1982 |
Effect of acute and chronic treatment with tricyclic antidepressants on 3-methoxy-4-hydroxyphenylethyleneglycol sulfate (MHPG-SO4) contents in various regions of rat brain.
Topics: Amitriptyline; Animals; Brain; Desipramine; Glycols; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains | 1982 |
Simultaneous liquid chromatographic analysis of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and nordoxepin.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline | 1981 |
The dexamethasone suppression test in the identification subtypes of depression differentially responsive to antidepressants [proceedings].
Topics: Adult; Age Factors; Aged; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Radioimmunoassay; Statistics as Topic | 1981 |
Liquid-chromatographic analysis for common tricyclic antidepressant drugs and their metabolites in serum or plasma with the technicon "FAST-LC" system.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Protriptyline | 1981 |
The depression-pain syndrome and its response to antidepressants.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Depression; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Pain; Syndrome | 1981 |
The measurement of antagonist potency and the importance of selective inhibition of agonist uptake processes.
Topics: Albuterol; Amitriptyline; Animals; Desipramine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Metanephrine; Methoxamine; Models, Biological; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Drug; Regression Analysis | 1981 |
Cognitive improvement associated with tricyclic antidepressant treatment of childhood major depressive illness.
Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Cognition; Depressive Disorder; Desipramine; Female; Humans; Intelligence; Male; Nortriptyline; Psychiatric Status Rating Scales | 1981 |
Reversed-phase liquid chromatography and gas chromatography/mass fragmentography compared for determination of tricyclic antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Nortriptyline | 1981 |
Tricyclic antidepressant blood levels: eight practical questions.
Topics: Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Intestinal Absorption; Nortriptyline | 1981 |
Effects of acutely and chronically administered antidepressants on the brain regional 3-methoxy-4-hydroxyphenylethyleneglycol sulfate in the forced swimming rat.
Topics: Amitriptyline; Animals; Brain; Desipramine; Glycols; Male; Methoxyhydroxyphenylglycol; Physical Exertion; Rats; Rats, Inbred Strains; Swimming | 1981 |
Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Synaptosomes; Viloxazine | 1981 |
The diagnosis and treatment of hidden depression.
Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Desipramine; Diagnosis, Differential; Female; Humans; Imipramine; Male; Psychotherapy; Social Isolation | 1981 |
Identification of misused drugs in the clinical laboratory. I. Tricyclics.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Doxepin; Humans; Loxapine; Male; Mass Spectrometry; Spectrophotometry, Ultraviolet; Stomach; Substance-Related Disorders | 1980 |
Quantitative analysis for tricyclic antidepressant drugs in plasma or serum by gas chromatography-chemical-ionization mass spectrometry.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1980 |
An external quality-control scheme for tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Desipramine; Humans; Imipramine; Laboratories; Nortriptyline; Quality Control; United Kingdom | 1980 |
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors | 1995 |
Prevention and treatment of the complications of diabetes mellitus.
Topics: Aged; Amitriptyline; Desipramine; Diabetic Neuropathies; Humans; Pain | 1995 |
Inhibition by antidepressants of glibenclamide-sensitive K+ currents in follicle-enclosed Xenopus oocytes.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antihypertensive Agents; Benzopyrans; Desipramine; Female; Glyburide; Imipramine; In Vitro Techniques; Oocytes; Potassium Channel Blockers; Potassium Channels; Xenopus laevis | 1994 |
Cocaine craving.
Topics: Adolescent; Amitriptyline; Cocaine; Desipramine; Humans; Hypotension, Orthostatic; Male; Risk Factors; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
Initiation of tricyclic treatment at full dose.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Administration Schedule; Humans; Hypotension, Orthostatic; Nortriptyline | 1994 |
Antidepressant treatment and chemical sympathectomy fail to modulate alpha 1-adrenoceptor sensitivity in mouse eye.
Topics: Administration, Topical; Amitriptyline; Animals; Antidepressive Agents; Benzamides; Desipramine; Down-Regulation; Fluoxetine; Injections, Intraperitoneal; Male; Methoxamine; Mice; Moclobemide; Oxidopamine; Phentolamine; Phenylephrine; Prazosin; Pupil; Receptors, Adrenergic, alpha-1; Sympathectomy, Chemical; Time Factors | 1993 |
A comparison of weight changes with fluoxetine, desipramine, and amitriptyline: a retrospective study of psychiatric inpatients.
Topics: Amitriptyline; Body Weight; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Hospitalization; Humans; Male; Mental Disorders; Retrospective Studies; Weight Gain | 1993 |
Concurrent liquid chromatographic measurement of fluoxetine, amitriptyline, imipramine, and their active metabolites norfluoxetine, nortriptyline, and desipramine in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Fluoxetine; Humans; Imipramine; Indicators and Reagents; Nortriptyline; Spectrophotometry, Ultraviolet | 1993 |
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation Studies as Topic; Forensic Medicine; Formaldehyde; Humans; Imipramine; Liver; Methylation; Nortriptyline; Poisoning; Temperature; Time Factors | 1993 |
Ca2+ release from inositol 1,4,5-trisphosphate-sensitive Ca2+ store by antidepressant drugs in cultured neurons of rat frontal cortex.
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Calcium; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Embryo, Mammalian; Frontal Lobe; Imipramine; Inositol 1,4,5-Trisphosphate; Kinetics; Mianserin; Neomycin; Neurons; Rats; Rats, Wistar | 1993 |
Improved arousal and initiation following tricyclic antidepressant use in severe brain injury.
Topics: Activities of Daily Living; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arousal; Brain Injuries; Cerebral Hemorrhage; Desipramine; Humans; Male; Reflex Sympathetic Dystrophy | 1996 |
Characteristics of the inhibitory effect of tricyclic antidepressants on histamine release from rat peritoneal mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Buffers; Calcium; Clomipramine; Desipramine; Histamine Release; Imipramine; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Structure-Activity Relationship | 1996 |
Modulation of glucocorticoid receptor gene expression by antidepressant drugs.
Topics: Adrenal Cortex Hormones; Amitriptyline; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Blotting, Northern; Cell Line; Desipramine; Dexamethasone; Fibroblasts; Gene Expression; Hippocampus; Hypothalamus; Mice; Mice, Transgenic; Neuroblastoma; Receptors, Glucocorticoid; Transfection | 1996 |
The effect of the potassium channel activator, cromakalim, on antidepressant drugs in the forced swimming test in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents; Benzopyrans; Cromakalim; Desipramine; Drug Interactions; Imipramine; Locomotion; Male; Mianserin; Mice; Minoxidil; Paroxetine; Physical Exertion; Potassium Channels; Pyrroles; Swimming | 1996 |
The effects of different monoaminergic antidepressants on the analgesia induced by spinal cord adrenal medullary transplants in the formalin test in rats.
Topics: Adrenal Medulla; Amitriptyline; Analgesia; Animals; Antidepressive Agents; Desipramine; Fluvoxamine; Formaldehyde; Male; Rats; Rats, Wistar; Spinal Cord | 1997 |
Effects of tricyclic and tetracyclic antidepressants on the three subtypes of GABA transporter.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biological Transport; Carrier Proteins; Desipramine; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; Maprotiline; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters | 1997 |
Treatments for postherpetic neuralgia.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Capsaicin; Desipramine; Herpes Zoster; Humans; Meta-Analysis as Topic; Neuralgia; Reproducibility of Results; Treatment Outcome | 1997 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Imipramine; Lung; Maprotiline; Mianserin; Microscopy, Electron; Nortriptyline; Organ Size; Perfusion; Pulmonary Edema; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley | 1997 |
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity | 1998 |
Isotope dilution gas chromatographic-mass spectrometric measurement of tricyclic antidepressant drugs. Utility of the 4-carbethoxyhexafluorobutyryl derivatives of secondary amines.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Deuterium; Drug Stability; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Nortriptyline; Reference Standards; Reproducibility of Results | 1998 |
In vitro effect of central nervous system active drugs on the ATPase-ADPase activity and acetylcholinesterase activity from cerebral cortex of adult rats.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Amitriptyline; Animals; Apyrase; Central Nervous System Agents; Cerebral Cortex; Desipramine; Diazepam; Hydrolases; Imipramine; In Vitro Techniques; Lithium; Rats; Synaptosomes | 1998 |
Stability of tricyclic antidepressants in formalin solutions.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Drug Stability; Forensic Medicine; Formaldehyde; Imipramine; Nortriptyline; Substance Abuse Detection; Time Factors | 1998 |
Effect of psychotropic drugs on taste responses in young and elderly persons.
Topics: Adult; Aged; Aging; Amitriptyline; Clomipramine; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Psychotropic Drugs; Taste; Trifluoperazine | 1998 |
Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Molecular Structure; Nortriptyline | 1998 |
On-line nonaqueous capillary electrophoresis and electrospray mass spectrometry of tricyclic antidepressants and metabolic profiling of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Calibration; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Mass Spectrometry; Molecular Structure | 1998 |
High concentrations of tricyclic antidepressants increase intracellular Ca2+ in cultured neural cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Desipramine; Neuroglia; Neurons; PC12 Cells; Rats | 1999 |
The relationship between pupil diameter and pain by the administration of morphine and antidepressant drugs in mice.
Topics: Amitriptyline; Analgesia; Analgesics, Opioid; Animals; Antidepressive Agents; Desipramine; Male; Mice; Morphine; Mydriasis; Pain; Pain Measurement; Pain Threshold; Pupil; Sertraline; Time Factors | 1999 |
Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Caffeine; Desipramine; Drug Evaluation, Preclinical; Fluoxetine; Male; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Spinal Nerves | 1999 |
Amitriptyline-induced loss of tight junction integrity in a human endothelial--smooth muscle cell bi-layer model.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Coculture Techniques; Desipramine; Electric Impedance; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Formazans; Humans; Imipramine; Muscle, Smooth, Vascular; Nortriptyline; Spectrometry, Fluorescence; Tetrazolium Salts; Tight Junctions; Umbilical Cord | 1999 |
Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Desipramine; Dexamethasone; Gene Expression Regulation; Haloperidol; Hippocampus; Ketanserin; Mianserin; Neurons; Paroxetine; Phentolamine; Propranolol; Radioligand Assay; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Sulpiride; Transcription, Genetic; Tritium | 1999 |
Selective increase of dopamine D3 receptor gene expression as a common effect of chronic antidepressant treatments.
Topics: Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Dopamine; Dynorphins; Electroshock; Fluoxetine; Gene Expression; Imipramine; Islands of Calleja; Limbic System; Male; Monoamine Oxidase Inhibitors; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substance P; Tranylcypromine | 2000 |
The effect of repeated amitriptyline and desipramine administration on cytokine release in C57BL/6 mice.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cell Division; Cytokines; Desipramine; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-2; Interleukin-4; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Organ Size; Spleen | 2000 |
Sample preparation with fiber-in-tube solid-phase microextraction for capillary electrophoretic separation of tricyclic antidepressant drugs in human urine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Imipramine; Nortriptyline; Specimen Handling | 2001 |
Tricyclic antidepressants directly depress human myocardial mechanical function independent of effects on the conduction system.
Topics: Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Culture Techniques; Desipramine; Dose-Response Relationship, Drug; Heart Atria; Humans; Myocardial Contraction; Neural Conduction; Probability; Reference Values; Sensitivity and Specificity | 2001 |
The effect of lofepramine and other related agents on the motility of Tetrahymena pyriformis.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; beta-Cyclodextrins; Cell Membrane; Cyclodextrins; Desipramine; Dose-Response Relationship, Drug; Image Processing, Computer-Assisted; Inhibitory Concentration 50; Lofepramine; Statistics, Nonparametric; Swimming; Tetrahymena pyriformis; Video Recording | 2002 |
Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kappa B and extracellular signal-regulated protein kinase activation.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Death; Cyclic AMP; Desipramine; DNA-Binding Proteins; Early Growth Response Protein 1; Fluoxetine; I-kappa B Proteins; Immediate-Early Proteins; Lysophospholipids; Mitochondria; Mitogen-Activated Protein Kinases; Neurons; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; PC12 Cells; Phosphorylation; Rats; Sphingosine; Transcription Factors | 2002 |
Gabapentin: new indication. In postherpetic neuralgia when amitriptyline fails.
Topics: Acetates; Amitriptyline; Anticonvulsants; Desipramine; Drug Approval; France; Herpes Zoster; Humans; Neuralgia; Pain; Randomized Controlled Trials as Topic; Safety; Treatment Outcome | 2002 |
[Effects of antidepressants on the expression of rat brain dopamine receptors].
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents; Brain; Desipramine; Male; Rats; Rats, Wistar; Receptors, Dopamine; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Sulpiride | 2002 |
Cortical alpha-adrenoceptor downregulation by tricyclic antidepressants in the rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Down-Regulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
INFLUENCE OF IMIPRAMINE AND RELATED PSYCHOACTIVE AGENTS ON THE EFFECT OF 5-HYDROXYTRYPTAMINE AND CATECHOLAMINES ON THE CAT NICTITATING MEMBRANE.
Topics: Amitriptyline; Animals; Antidepressive Agents; Catecholamines; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Epinephrine; Imipramine; Nictitating Membrane; Norepinephrine; Pharmacology; Promazine; Psychotropic Drugs; Research; Serotonin; Tranquilizing Agents | 1963 |
[DRUGS ACTING ON THE NERVOUS SYSTEM. (2). WITH SPECIAL REFERENCE TO TRANQUILIZERS AND ANTIDEPRESSIVE AGENTS].
Topics: Amides; Amitriptyline; Antidepressive Agents; Benactyzine; Chemical Phenomena; Chemistry; Chlordiazepoxide; Desipramine; Diazepam; Haloperidol; Humans; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Isocarboxazid; Meprobamate; Methylphenidate; Monoamine Oxidase Inhibitors; Nervous System; Nialamide; Pharmacology; Phenelzine; Piperidines; Tranquilizing Agents; Tranylcypromine; Tryptamines | 1963 |
ON THE ANTIARRHYTHMIC EFFECT OF SOME THYMOLEPTICS (AMITRIPTYLINE, IMIPRAMINE, TRIMEPROPIMINE AND DESMETHYLIMIPRAMINE).
Topics: Aconitum; Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Bradycardia; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Chlorides; Desipramine; Electrocardiography; Guanethidine; Imipramine; Pharmacology; Quinidine; Rats; Research; Reserpine; Tachycardia; Ventricular Fibrillation | 1964 |
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine | 1964 |
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine | 1964 |
EFFECT OF IMIPRAMINE AND SOME ANALOGUES ON THE UPTAKE OF 5-HYDROXYTRYPTAMINE BY HUMAN BLOOD PLATELETS IN VITRO.
Topics: Amitriptyline; Antidepressive Agents; Blood Platelets; Chlorpromazine; Desipramine; Humans; Imipramine; In Vitro Techniques; Metabolism; Orphenadrine; Pharmacology; Research; Serotonin | 1964 |
[THIN LAYER CHROMATOGRAPHIC SEPARATION OF PSYCHOPHARMACOLOGICAL AGENTS WITH ANTIDEPRESSIVE ACTION].
Topics: Amitriptyline; Antidepressive Agents; Chromatography; Chromatography, Thin Layer; Desipramine; Hydrazines; Imipramine; Iproniazid; Isocarboxazid; Isoniazid; Nialamide; Phenelzine; Research; Tranylcypromine | 1963 |
[RESEARCH ON THE AMINE POTENTIATING EFFECT OF ANTIDEPRESSIVE AGENTS IN RABBITS].
Topics: Amines; Amitriptyline; Angiotensins; Antidepressive Agents; Desipramine; Epinephrine; Imipramine; Lysergic Acid Diethylamide; Norepinephrine; Pharmacology; Rabbits; Research; Serotonin; Thioridazine | 1964 |
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervous System; Bradycardia; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Desipramine; Dogs; Epinephrine; Imipramine; Mice; Norepinephrine; Pharmacology; Promazine; Rats; Research; Reserpine; Sleep; Toxicology; Tranquilizing Agents; Vasomotor System; Yohimbine | 1964 |
COMBINING THE ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Phenelzine; Psychopharmacology; Toxicology | 1965 |
[RESEARCH ON ANTICHOLINERGIC EFFECTS OF ANTIDEPRESSIVE SUBSTANCES IN THE RABBIT].
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Bradycardia; Cholinergic Antagonists; Desipramine; Imipramine; Parasympatholytics; Pharmacology; Rabbits; Research; Salivation; Sialorrhea | 1964 |
[PROGRESS OF DEPRESSIVE DISEASES UNDER DRUG THERAPY].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Desipramine; Drug Therapy; Humans; Imipramine; Nialamide; Prognosis; Psychopharmacology; Thioridazine | 1964 |
THE DIAGNOSIS AND MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Classification; Depression; Depressive Disorder; Desipramine; Diagnosis; Drug Therapy; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nortriptyline; Tyramine | 1965 |
POTENTIATION OF NOREPINEPHRINE IN THE ISOLATED VAS DEFERENS OF THE RAT BY SOME CNS STIMULANTS AND ANTIDEPRESSANTS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Humans; Imipramine; Male; Methylphenidate; Norepinephrine; Pharmacology; Phenmetrazine; Piperidines; Rats; Research; Tranquilizing Agents; Vas Deferens | 1965 |
CORRELATIONS BETWEEN EXPERIMENTAL AND CLINICAL RESULTS WITH ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Imipramine; Pharmacology; Rabbits; Rats; Research; Reserpine; Tetrabenazine | 1965 |
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlorpromazine; Chlorprothixene; Desipramine; Eyelids; Imipramine; Mice; Nortriptyline; Peptic Ulcer; Pharmacology; Rats; Research; Reserpine; Toxicology; Tranquilizing Agents | 1964 |
PHARMACOLOGICAL PROPERTIES OF THE DESMETHYL DERIVATIVES OF SOME ANTIDEPRESSANTS OF IMIPRAMINE TYPE.
Topics: Amitriptyline; Animals; Antidepressive Agents; Caffeine; Desipramine; Hypothermia; Hypothermia, Induced; Imipramine; Injections, Intraperitoneal; Mice; Nortriptyline; Pentylenetetrazole; Peptic Ulcer; Rats; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin; Strychnine; Toxicology; Tranquilizing Agents | 1965 |
Excess fatality from desipramine and dosage recommendations.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Databases, Factual; Desipramine; Drug Overdose; Humans; Imipramine; Nortriptyline; United Kingdom; United States | 2004 |
A comparison of the chronic treatment effects of venlafaxine and other antidepressants on serotonin and norepinephrine transporters.
Topics: Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Brain; Cyclohexanols; Desipramine; Male; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Venlafaxine Hydrochloride | 2006 |
Deliberate misuse of tricyclic antidepressants by intravenous drug users--case studies and report.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cause of Death; Desipramine; Female; Humans; Male; Middle Aged; Risk Assessment; Sampling Studies; Substance Abuse, Intravenous | 2005 |
Excess fatality from desipramine in children and adolescents.
Topics: Adolescent; Amitriptyline; Child; Desipramine; Doxepin; Humans; Imipramine; Incidence; Mortality; Nortriptyline; Prevalence; Substance-Related Disorders | 2006 |
Characterization of cytotoxic actions of tricyclic antidepressants on human HT29 colon carcinoma cells.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Colonic Neoplasms; Desipramine; DNA Fragmentation; HT29 Cells; Humans; Imipramine; Membrane Potentials; Mitochondrial Membranes; Time Factors | 2006 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine | 2007 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Chromatography, Liquid; Clomipramine; Desipramine; Humans; Imipramine; Nortriptyline; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2007 |
In vitro biotransformation of amitriptyline and imipramine with rat hepatic S9 fraction: evaluation of the toxicity with Spirotox and Thamnotoxkit F Tests.
Topics: Amitriptyline; Animals; Anostraca; Biotransformation; Ciliophora; Desipramine; Imipramine; Lethal Dose 50; Liver; Male; Nortriptyline; Rats; Rats, Sprague-Dawley; Toxicity Tests; Water Pollutants, Chemical | 2008 |
Histamine uptake into human vascular endothelial cells and influence of three different antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Cells, Cultured; Citalopram; Desipramine; Dose-Response Relationship, Drug; Endothelial Cells; Histamine; Humans | 2008 |
Serotoninergic and non-serotoninergic effects of two tricyclic antidepressants on visceral nociception in a rat model.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Models, Animal; Nociceptors; Rats; Reserpine; Serotonin | 2009 |
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2009 |
Perisurgical amitriptyline produces a preventive effect on afferent hypersensitivity following spared nerve injury.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain-Derived Neurotrophic Factor; Desipramine; Glial Cell Line-Derived Neurotrophic Factor; Hyperalgesia; Immunohistochemistry; Male; Neurons, Afferent; Norepinephrine; Oxidopamine; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sympatholytics | 2009 |
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride | 2010 |
IFN-gamma reduction by tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Cytokines; Depressive Disorder; Desipramine; Desvenlafaxine Succinate; Female; Humans; Imipramine; In Vitro Techniques; Interferon-gamma; Male; Nortriptyline; Venlafaxine Hydrochloride | 2010 |
Sildenafil, a phosphodiesterase type 5 inhibitor, enhances the antidepressant activity of amitriptyline but not desipramine, in the forced swim test in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Chromatography, High Pressure Liquid; Depression; Desipramine; Drug Interactions; Drug Synergism; Male; Mice; Motor Activity; Muscarinic Antagonists; Phosphodiesterase Inhibitors; Piperazines; Purines; Scopolamine; Sildenafil Citrate; Spectrophotometry, Ultraviolet; Sulfones; Swimming | 2012 |
Comparative evaluation of the effect of tricyclic antidepressants on inducible nitric oxide synthase expression in neuropathic pain model.
Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cerebellum; Clomipramine; Desipramine; Enzyme Inhibitors; Gene Expression; Guanidines; Hippocampus; Immunohistochemistry; Male; Neuralgia; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve | 2012 |
Tricyclic antidepressants exhibit variable pharmacological profiles at the α(2A) adrenergic receptor.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arrestins; Desipramine; Endocytosis; HEK293 Cells; Humans; Imipramine; Mice; Receptors, Adrenergic, alpha-2 | 2014 |
Tricyclic antidepressants for the treatment of tenesmus associated with rectal prolapse.
Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Defecation; Desipramine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nortriptyline; Rectal Diseases; Rectal Prolapse; Retrospective Studies; Treatment Outcome | 2015 |
Tricyclic Antidepressants Amitriptyline and Desipramine Induced Neurotoxicity Associated with Parkinson's Disease.
Topics: Adenosine Triphosphate; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antioxidants; Apoptosis; Cell Line, Tumor; Desipramine; Dopaminergic Neurons; Humans; Male; Mice, Inbred C57BL; Mitochondria; Parkinson Disease; Reactive Oxygen Species | 2015 |
Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS).
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Nortriptyline; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
Liquid-Phase Microextraction and Gas Chromatographic-Mass Spectrometric Analysis of Antidepressants in Vitreous Humor: Study of Matrix Effect of Human and Bovine Vitreous and Saline Solution.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cattle; Desipramine; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Liquid Phase Microextraction; Sodium Chloride; Vitreous Body | 2016 |
Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Atomoxetine Hydrochloride; Brain; Chlorpromazine; Citalopram; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neurotransmitter Agents; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2017 |
Carbon Nanohorn Suprastructures on a Paper Support as a Sorptive Phase.
Topics: Amitriptyline; Antidepressive Agents; Carbon; Desipramine; Humans; Limit of Detection; Mass Spectrometry; Mianserin; Paper; Solid Phase Microextraction; Solvents; Urine | 2018 |
6-nitrodopamine is a major endogenous modulator of human vas deferens contractility.
Topics: Adrenergic Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Dopamine; Doxazosin; Epinephrine; Humans; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Prazosin; Rats; Receptors, Adrenergic; Tamsulosin; Tandem Mass Spectrometry; Vas Deferens | 2022 |
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma.
Topics: Acetonitriles; Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Maprotiline; Mass Spectrometry; Methanol; Nortriptyline; Reproducibility of Results; Spectrum Analysis; Vacuum; Venlafaxine Hydrochloride | 2022 |
Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Ceramides; Desipramine; Endothelial Cells; Extracellular Vesicles; Fluoxetine; Ischemia; Mice; Proteomics | 2022 |
Calcium-Dependent Interplay of Lithium and Tricyclic Antidepressants, Amitriptyline and Desipramine, on
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium, Dietary; Desipramine; Lithium; Rats; Receptors, N-Methyl-D-Aspartate | 2022 |
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction | 2023 |