amitriptyline has been researched along with debrisoquin in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Brockmöller, J; Müller, N; Roots, I | 1 |
| Brøsen, K; Gram, LF; Kragh-Sørensen, P | 1 |
| Aberg-Wistedt, A; Bertilsson, L; Dahl-Puustinen, ML | 1 |
| Dawling, S | 1 |
| Bertilsson, L; Sjöqvist, F | 1 |
| Baumann, P; Jonzier-Perey, M; Koeb, L; Küpfer, A; Schöpf, J; Tinguely, D | 1 |
| Baumann, P | 1 |
| Bertilsson, L; Mellström, B; Säwe, J; Sjöqvist, F | 1 |
| Baumann, P; Jonzier-Perey, M; Koeb, L; Schnyder, C; Wertheimer, J | 1 |
| Aberg-Wistedt, A; Bertilsson, L; Gustafsson, LL; Nordin, C | 1 |
| Bertilsson, L; Lou, YC; Mellström, B; Säwe, J; Sjöqvist, F | 1 |
| Fieller, NR; Silas, JH; Smith, AJ; Tucker, GT | 1 |
| Gu, NF; Jiang, WD; Yin, JL; Yu, P; Zhang, XH | 1 |
2 review(s) available for amitriptyline and debrisoquin
| Article | Year |
|---|---|
Is there a practical alternative to therapeutic drug monitoring in therapy with tricyclic antidepressants?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Debrisoquin; Half-Life; Humans; Monitoring, Physiologic; Phenotype | 1988 |
Slow hydroxylation of tricyclic antidepressants--relationship to polymorphic drug oxidation.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Debrisoquin; Desipramine; Female; Humans; Hydroxylation; Kinetics; Male; Middle Aged; Nortriptyline; Phenotype; Polymorphism, Genetic; Smoking; Twins, Dizygotic; Twins, Monozygotic | 1986 |
2 trial(s) available for amitriptyline and debrisoquin
| Article | Year |
|---|---|
[The use of low-dose amitriptyline in psychogeriatrics. A clinical, pharmacokinetic and pharmacogenetic study].
Topics: Aged; Amitriptyline; Debrisoquin; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; Hydroxylation; Male; Nortriptyline; Psychological Tests | 1985 |
Accumulation of debrisoquine by platelets in vivo: a model of events at the peripheral adrenergic neurone.
Topics: Amitriptyline; Blood Platelets; Debrisoquin; Erythrocytes; Humans; Hydroxylation; Hypertension; Isoquinolines; Models, Biological; Neurons; Sympathetic Nervous System; Time Factors | 1980 |
11 other study(ies) available for amitriptyline and debrisoquin
| Article | Year |
|---|---|
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Extremely long plasma half-life of amitriptyline in a woman with the cytochrome P450IID6 29/29-kilobase wild-type allele--a slowly reversible interaction with fluoxetine.
Topics: Alleles; Amitriptyline; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Debrisoquin; Depression; Drug Interactions; Female; Fluoxetine; Fluvoxamine; Half-Life; Humans; Middle Aged; Nortriptyline; Phenotype; Spectrophotometry, Ultraviolet | 1991 |
Extremely slow metabolism of amitriptyline but normal metabolism of imipramine and desipramine in an extensive metabolizer of sparteine, debrisoquine, and mephenytoin.
Topics: Administration, Oral; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Thin Layer; Debrisoquin; Desipramine; Drug Interactions; Humans; Imipramine; Male; Mephenytoin; Phenotype; Quinidine; Sparteine | 1991 |
Glucuronidation of amitriptyline in man in vivo.
Topics: Administration, Oral; Adult; Amitriptyline; Chemical Phenomena; Chemistry; Debrisoquin; Humans; Hydroxylation; Middle Aged | 1989 |
Amitriptyline pharmacokinetics and clinical response: II. Metabolic polymorphism assessed by hydroxylation of debrisoquine and mephenytoin.
Topics: Adult; Amitriptyline; Debrisoquin; Depressive Disorder; Female; Humans; Hydantoins; Hydroxylation; Isoquinolines; Kinetics; Male; Mephenytoin; Middle Aged; Nortriptyline; Phenotype; Polymorphism, Genetic | 1986 |
New aspects in research on blood levels and bioavailability of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Biological Availability; Debrisoquin; Depressive Disorder; Humans; Kinetics; Maprotiline; Mephenytoin; Nortriptyline | 1986 |
Amitriptyline metabolism: association with debrisoquin hydroxylation in nonsmokers.
Topics: Administration, Oral; Adult; Amitriptyline; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Debrisoquin; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Nortriptyline; Phenotype | 1986 |
Extremely rapid hydroxylation of debrisoquine: a case report with implication for treatment with nortriptyline and other tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Debrisoquin; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Hydroxylation; Isoquinolines; Lithium; Nortriptyline | 1985 |
Amitriptyline metabolism: relationship to polymorphic debrisoquine hydroxylation.
Topics: Adult; Amitriptyline; Debrisoquin; Female; Humans; Kinetics; Male; Middle Aged; Nortriptyline; Smoking | 1983 |
[Relationship between amitriptyline metabolism and polymorphic debrisoquine hydroxylation in native Chinese volunteers].
Topics: Adult; Amitriptyline; Asian People; Debrisoquin; Humans; Hydroxylation; Male; Metabolic Clearance Rate; Nortriptyline; Phenotype; Polymorphism, Genetic; Species Specificity | 1993 |