amitriptyline and cyclobenzaprine

amitriptyline has been researched along with cyclobenzaprine in 178 studies

Research

Studies (178)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (22.47)	18.7374
1990's	22 (12.36)	18.2507
2000's	41 (23.03)	29.6817
2010's	62 (34.83)	24.3611
2020's	13 (7.30)	2.80

Authors

Authors	Studies
Henderson, JD; Wilkerson, RD	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL	1
Brown, BR; Womble, J	1
Hucker, HB; Stauffer, SC	2
Barnes, CD; Hughes, MJ; Light, KE; Messiha, FS	1
Basmajian, JV	2
Adams, WL; Barnes, CD	1
Share, NN	3
Belvedere, G; Frigerio, A; Pantarotto, C; Rovei, V	1
Barnes, CD	1
McFarlane, CS; Share, NN	1
Edinboro, LE; Poklis, A	1
De Vita, S; Fossaluzza, V	1
Felson, DT; Goldenberg, DL; Simms, RW	1
Lue, FA; Moldofsky, H; Reynolds, WJ; Saskin, P	1
Romano, TJ	1
Block, SR; Gratwick, GM; Quimby, LG; Whitney, CD	1
Hamaty, D; Howard, CW; Howard, R; Patten, MS; Valentine, JL; Wakefield, V	1
Goldenberg, DL	2
Calderon, J; Gillette, P; O'Riordan, W; Stennes, RL	1
Flannery, DB	1
Snapinn, SM	1
Andrews, RP; Bennett, RM; Campbell, SM; Clark, SR; Gatter, RA; Scarola, JA	1
Dube, J; Katz, WA	1
Gatter, RA	1
Flood, JG; Puopolo, PR	1
Giardina, EG; Schneider, M	1
Ciancio, SG	1
Ambre, JJ	1
Bayne, WF; Constanzer, ML; Vincek, WC	1
Harsch, HH	1
Bartow, TJ; Heckerling, PS	1
Antelman, SM; Chiodo, LA; DeGiovanni, LA; Kocan, D; Perel, JM	1
Linden, CH; Lindzon, RD; Mitchiner, JC; Rumack, BH	1
Novack, GD; Zwolshen, JM	1
Beeber, AR; Manring, JM	1
Barnes, CD; Lang, IM	2
Heinitz, ML	1
Commissiong, JW; Karoum, F; Neff, NH; Reiffenstein, RJ	1
Barnes, CD; Fung, SJ; Gintautas, J	1
Chavez, C; Constanzer, M; Matuszewski, B	1
Harris, RS; Theoharides, TC; Weckstein, D	1
Danielson, ND; Holeman, JA	1
Baron, M; Bell, MJ; Bykerk, VP; Carette, S; Edworthy, SM; Fam, AG; Haraoui, B; Koehler, BE; McCain, GA; Reynolds, WJ	1
Bellandi, F; Cantini, F; Di Munno, O; Niccoli, L	1
Ito, Y; Iwasaki, N; Kakiuchi, M; Kato, H; Muramatsu, H; Ohashi, T; Sawanishi, H	1
Gudewicz, TM; Jones, R; Levine, B; Peterson, B; Smith, ML	1
Goodnick, PJ; Sandoval, R	1
Chapron, D; Engel, PA	1
Alim, M; Edelson, GW	1
Cheng, H; Liu, L; Wang, RW	1
Fink, M	1
Hasegawa, Y; Kobayashi, H; Ono, H	1
Cerniglia, CE; Deck, J; Evans, FE; Freeman, JP; Yang, Y; Zhang, D	1
Lines, C; Mant, T; Raskin, S; Reines, S; Traub, M	1
Yong, JN	1
Wahba, WW; Winek, CL	1
Douglass, MA; Levine, DP	1
Borgaonkar, MR; Lumb, B	1
Bhaskara, SM; Knudson, GA; O'Neil, BA	1
Buttaro, T; Jalali, S; Lofland, JH; Shermock, S; Szarlej, D	1
Browning, R; Jackson, JL; O'Malley, PG	1
Chavez-Eng, CM; Constanzer, ML; King, JD; Korn, SH; Winchell, GA	1
Herman, CR; Look, JO; Rindal, DB; Schiffman, EL	1
Chang, SI; Harwood, MI	1
Razaghi, AM; Schwartz, JB	2
Argoff, CE	1
van de Laar, MA; Zijlstra, TR	1
Honda, M; Nishida, T; Ono, H	1
D'Amico, FJ; Frater, CR; Turturro, MA	1
Borenstein, DG; Korn, S	1
Cutino, L; Spiller, HA	1
Jackson, JL; O'Malley, PG; Tofferi, JK	1
Toth, PP; Urtis, J	1
Riley-Lazo, KP; Rosenlicht, NZ	1
Meyer, MA	1
Borenstein, D; Brown, RL; Childers, MK; Gershon, S; Hale, ME; Harrison, DD; Laudadio, C; Petri, M; Wan, GJ	1
Menon, Y; Quintos-Macasa, AM; Serebro, L	1
Aguilar, I; Aranda Regules, JM; Faus, V; Herrera Galante, A; Martinez Barquin, DM; Mendez, C; Perea-Milla, E; Silva, LC; Vas, J	1
Brown, DR; Keegan, MT; Rabinstein, AA	1
Dixon, SP; Lodi, A; Miller, JH; Skellern, GG	1
Darwish, M; Hellriegel, ET; Xie, F	1
Day, LT; Jeanmonod, RK	1
Itro, A; Rauso, R; Santagata, M; Santillo, V; Tartaro, G	1
Anderson, JM; Brodsky, MC	1
Darwish, M; Xie, F	2
Chang, S; Darwish, M; Hellriegel, ET	1
Altman, CA; Borenstein, DG; Malanga, GA; Ruoff, GE; Weil, AJ; Xie, F	1
Arancibia, A; Costa, E; Gai, MN	1
Gillman, PK	1
Andriolo, RB; Atallah, AN; da Silva, EM; El Dib, R; Grossmann, E; Januzzi, E; Leite, FM	1
Fischer, F; Jauss, M; Muller, SC; Reuss, R; Reuter, I; Stolz, E	1
Grosberg, BM; Robbins, MS	1
Henretig, FM; Menard-Katcher, C; Osterhoudt, KC	1
Khwaja, SM; Minnerop, M; Singer, AJ	1
Altman, CA; Nalamachu, S; Ruoff, GE; Taylor, DR; Weil, AJ; Xie, F	1
Bebarta, VS; Borys, DJ; Maddry, J; Morgan, DL	2
Darwish, M; Hellriegel, ET	2
Altman, CA; Landy, S; Xie, F	1
Abdala, N; Abdalla, C; Abrahão, A; Barsottini, OG; Braga-Neto, P; Pedroso, JL; Rivero, RL	1
Archambault, WT; Harris, HW; Kwong, T; Lederman, S; Moldofsky, H	1
Calazans, AC; de Oliveira E Silva, ED; de Santana Santos, T; Gomes, AC; Martins-Filho, PR; Silva, LC	1
Mestres, J; Oprea, TI; Seifert, SA	1
Abernethy, DR; Bai, JP; Burkhart, K; Xie, HG; Zhichkin, P	1
Borges, DC; Borges, NC; Donato, JL; Moreira, RF; Moreira, RP; Moreno, P; Moreno, RA; Rezende, VM; Santana, JM	1
Chen, X; Jiang, H; Li, D; Peng, K; Qian, Z; Xiang, Y; Zheng, H; Zhou, L	1
Thomas, RJ	1
Burger, J; Coelho, C; Elgoyhen, AB; Figueiredo, R; Frank, E; Landgrebe, M; Langguth, B; Schecklmann, M	1
De Ridder, D; Figueiredo, R; Vanneste, S	1
Gordin, VN; Lamberg, JJ	1
Kunka, CA; Ota, KS; Sheikh, M	1
Calafat, AM; Hauser, R; Hernández-Díaz, S; Kelley, KE; Mitchell, AA; Su, YC	1
Perza, MN; Rosini, JM; Schneider, LA	1
Sederholm, B; Shprecher, D; Sloan, CT	1
Chuttani, K; Mathur, R; Mishra, AK; Misra, A; Naik, S; Patel, D	1
Bicknell, LT; Sanches, M; Schatte, DJ	1
Aly, A; Barbin, C; Fonseca, R; Martinez, H; Moreira, A	1
Brioschi, TM; Ching, TH; Kano, EK; Koono, EE; Porta, V; Schramm, SG; Serra, CH	1
Alencar, FG; Becker, A; Viana, PG; Zamperini, C	1
Blair, C; Le Prell, C; Lobarinas, E; Spankovich, C	1
Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL	1
Awad, NI; Bridgeman, PJ; Jeges, J; McCoy, JV; Page, E; Westrol, MS	1
Brennan-Taylor, MK	1
Bijur, PE; Davitt, M; Dym, AA; Esses, D; Friedman, BW; Gallagher, EJ; Holden, L; Solorzano, C	1
Blum, LM; Scanlon, KA; Starkey, SJ; Stoppacher, R	1
Allan, GM; Braschi, E; Garrison, S	1
McCarthy, J	1
Chaffee, DM	1
Cioroiu, BI; Cioroiu, ME; Grigoriu, IC; Lazar, MI; Lupuleasa, R; Niculaua, M	1
Amris, K; Atzeni, F; Branco, J; Choy, E; Dean, LE; Dincer, F; Fluß, E; Häuser, W; Jones, GT; Kosek, E; Kronisch, C; Leino-Arjas, P; Longley, K; Macfarlane, GJ; Makri, S; McCarthy, GM; Perrot, S; Sarzi-Puttini, P; Taylor, A	1
Barna, M; Brewer, WE; Dongari, N; Lee, LA; Mastrianni, KR; Morgan, SL	1
Borja Segade, J; Feo Brito, JF; Galindo Bonilla, PA; García Arpa, M; García Rodríguez, C; García Rodríguez, R; Gómez Torrijos, E; Mendez Díaz, Y	1
Frazer, K; Stevermer, JJ	1
Kennedy, DJ; Kumbhare, D; Schneider, BJ	1
Gottlieb, M; Njie, A	1
Clark, S; Kokkirala, A; Rasla, S; Siddique, O	1
Chambers, RS; DeMonbrun, AG; Dolcourt, BA; Kawai, Y; Malas, NM; Nolan, DA; Quasney, MW	1
Abengózar, MA; Almeida-Amaral, EE; Andrade-Neto, VV; Barbas, C; Cunha-Júnior, EF; da Costa-Silva, TA; Galisteo Junior, AJ; Lima, ML; Rivas, L; Tempone, AG; Torres-Santos, EC	1
Bell, P; Glinn, MA; Harvey, A; Lickteig, AJ; Rappold, B; Recer, S; Salske, M; Stensland, J; Weber, L	1
Ingalsbe, GS; Kim, HS; Lank, PM	1
Adar, L; Conner, JB; Dragone, J; Janka, L; Rabinovich-Guilatt, L; Zarycranski, W	1
Macdonald, JB; Nelson, SA; Sekulic, A; Yang, YW	1
Darwish, HW; Darwish, IA; Naguib, IA	1
Dorsey, SG; Griffioen, MA; O'Toole, RV; Renn, CL; Ziegler, ML	1
Cohen, JY; Guilbault, A	1
Ahmad, K; Baig, MH; Choi, I; Imran, M; Rabbani, G; Rahman, S	1
Baker, T; Burra, B; Datta, P; Hale, TW; Rewers-Felkins, K	1
Amorim, JBO; de Moraes, MB; Nascimento, RD; Raldi, FV; Santos, LM; Sato, FRL	1
El Abass Mohamed, SA; Walash, MI	1
Alsaab, S; Cobb, C; Haidari, M; Mansani, S; Ponds, D; Romero, L	1
de Assis, MR; Dos Santos Paiva, E; Helfenstein, M; Heymann, RE; Martinez, JE; Pollak, DF; Provenza, JR; Ranzolin, A; Rezende, MC; Ribeiro, LS; Souza, EJR	1
Caron, J; Halseth, A; Kay, G; Kaye, R; Wessel, T	1
Al Yafi, MN; Al-Halabi, B; Alnaeem, H; ElHawary, H; Fouda-Neel, O; Xu, L	1
Robertson, CE; Steel, SJ	1
Daugherty, BL; Engels, J; Gendreau, J; Gendreau, RM; Lederman, S; Peters, A; Peters, P; Sullivan, GM; Vaughn, B; Weathers, FW	1
Buyukgoz, C; Gangu, S; Gowani, F; Kimura, D	1
Cheshmehkani, A; Karmokar, PF; Moniri, NH; Senatorov, IS; Singh, K	1
Dean, DA; Hossain, E; Katemauswa, M; Lesani, M; Liu, Z; McCall, LI; Parab, AR	1
Alwan, R; O'Neal, M	1
Bloom, J; Hoffman, RS	1
Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM	1
Abengózar, MA; Barbas, C; Borborema, SET; Godzien, J; Lima, ML; López-Gonzálvez, Á; Rivas, L; Tempone, AG; Torres-Santos, EC	1

Reviews

18 review(s) available for amitriptyline and cyclobenzaprine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Treatment of fibromyalgia syndrome. Rheumatic diseases clinics of North America, 1989, Volume: 15, Issue:1 Topics: Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Fibromyalgia; Humans; Syndrome	1989
A review of the role of tricyclic medications in the treatment of fibromyalgia syndrome. The Journal of rheumatology. Supplement, 1989, Volume: 19 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biomechanical Phenomena; Clinical Trials as Topic; Fibromyalgia; Humans; Pain; Pain Measurement; Sleep; Syndrome	1989
Cyclobenzaprine in the treatment of acute muscle spasm: review of a decade of clinical experience. Clinical therapeutics, 1988, Volume: 10, Issue:2 Topics: Amitriptyline; Humans; Muscle Relaxants, Central; Spasm	1988
Psychotropic treatment of chronic fatigue syndrome and related disorders. The Journal of clinical psychiatry, 1993, Volume: 54, Issue:1 Topics: 5-Hydroxytryptophan; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Fatigue Syndrome, Chronic; Fibromyalgia; Humans; Lithium Carbonate; Psychotropic Drugs; S-Adenosylmethionine	1993
Syncope in a young woman with chronic back pain. Hospital practice (Office ed.), 1993, Jun-15, Volume: 28, Issue:6 Topics: Adult; Amitriptyline; Back Pain; Diagnosis, Differential; Emergency Medical Services; Female; Humans; Hypoglycemia; Muscle Relaxants, Central; Syncope	1993
Cyclobenzaprine and back pain: a meta-analysis. Archives of internal medicine, 2001, Jul-09, Volume: 161, Issue:13 Topics: Amitriptyline; Back Pain; Humans; Muscle Relaxants, Central; Randomized Controlled Trials as Topic	2001
Clinical inquiries. What is the most effective treatment for acute low back pain? The Journal of family practice, 2002, Volume: 51, Issue:2 Topics: Acetaminophen; Adrenal Cortex Hormones; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Bed Rest; Drug Therapy, Combination; Evidence-Based Medicine; Exercise; Humans; Injections, Epidural; Low Back Pain; Manipulation, Spinal; Muscle Relaxants, Central	2002
Pharmacologic management of chronic pain. The Journal of the American Osteopathic Association, 2002, Volume: 102, Issue:9 Suppl 3 Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Drug Therapy, Combination; Humans; Pain	2002
Treatment of fibromyalgia with cyclobenzaprine: A meta-analysis. Arthritis and rheumatism, 2004, Feb-15, Volume: 51, Issue:1 Topics: Amitriptyline; Databases, Factual; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome	2004
Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. Clinical therapeutics, 2004, Volume: 26, Issue:9 Topics: Amitriptyline; Carisoprodol; Humans; Low Back Pain; Muscle Relaxants, Central; Oxazolidinones; Randomized Controlled Trials as Topic; Risk Assessment	2004
Cyclobenzaprine for the treatment of myofascial pain in adults. The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3 Topics: Adult; Amitriptyline; Anesthetics, Local; Clonazepam; Fascia; Humans; Lidocaine; Muscle Relaxants, Central; Muscular Diseases; Pain; Randomized Controlled Trials as Topic	2009
Pharmacokinetic profile of once-daily cyclobenzaprine extended-release. Expert opinion on drug metabolism & toxicology, 2010, Volume: 6, Issue:11 Topics: Aged; Amitriptyline; Animals; Delayed-Action Preparations; Drug Administration Schedule; Food-Drug Interactions; Humans; Muscle Relaxants, Central; Randomized Controlled Trials as Topic; Spasm	2010
Cyclobenzaprine for acute back pain. Canadian family physician Medecin de famille canadien, 2015, Volume: 61, Issue:12 Topics: Acute Disease; Adult; Aged; Amitriptyline; Back Pain; Humans; Middle Aged; Muscle Relaxants, Central; Pain Management	2015
Myalgias and Myopathies: Fibromyalgia. FP essentials, 2016, Volume: 440 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Behavior Therapy; Combined Modality Therapy; Exercise Therapy; Female; Fibromyalgia; Humans; Muscular Diseases; Myalgia; Patient Education as Topic; Selective Serotonin Reuptake Inhibitors	2016
Cyclobenzaprine in the Treatment of Low Back Pain. American family physician, 2016, Feb-01, Volume: 93, Issue:3 Topics: Amitriptyline; Humans; Low Back Pain; Muscle Relaxants, Central	2016
EULAR revised recommendations for the management of fibromyalgia. Annals of the rheumatic diseases, 2017, Volume: 76, Issue:2 Topics: Activities of Daily Living; Acupuncture Therapy; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Capsaicin; Cognitive Behavioral Therapy; Europe; Evidence-Based Medicine; Exercise Therapy; Fatigue; Fibromyalgia; Human Growth Hormone; Humans; Hydrotherapy; Hypnosis; Manipulation, Chiropractic; Massage; Mind-Body Therapies; Mindfulness; Monoamine Oxidase Inhibitors; Pain; Practice Guidelines as Topic; S-Adenosylmethionine; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Sleep; Societies, Medical; Sodium Oxybate; Treatment Outcome	2017
First Bite Syndrome: What Neurologists Need to Know. Current pain and headache reports, 2021, Mar-24, Volume: 25, Issue:5 Topics: Acetylcholine Release Inhibitors; Amitriptyline; Analgesics, Non-Narcotic; Botulinum Toxins; Carotid Body Tumor; Facial Pain; Head and Neck Neoplasms; Horner Syndrome; Humans; Muscle Relaxants, Central; Otorhinolaryngologic Surgical Procedures; Parapharyngeal Space; Parotid Gland; Parotid Neoplasms; Postoperative Complications; Squamous Cell Carcinoma of Head and Neck; Tonsillar Neoplasms	2021

Trials

40 trial(s) available for amitriptyline and cyclobenzaprine

Article	Year
Cyclobenzaprine in intractable pain syndromes with muscle spasm. JAMA, 1978, Sep-08, Volume: 240, Issue:11 Topics: Adult; Amitriptyline; Clinical Trials as Topic; Diazepam; Dibenzocycloheptenes; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Pain, Intractable; Syndrome	1978
Cyclobenzaprine hydrochloride effect on skeletal muscle spasm in the lumbar region and neck: two double-blind controlled clinical and laboratory studies. Archives of physical medicine and rehabilitation, 1978, Volume: 59, Issue:2 Topics: Administration, Oral; Amitriptyline; Computers; Dibenzocycloheptenes; Double-Blind Method; Drug Evaluation; Electromyography; Humans; Lumbosacral Region; Movement; Muscle Relaxants, Central; Muscle Spasticity; Neck; Placebos	1978
Combined therapy with cyclobenzaprine and ibuprofen in primary fibromyalgia syndrome. International journal of clinical pharmacology research, 1992, Volume: 12, Issue:2 Topics: Adult; Amitriptyline; Blood Sedimentation; Drug Therapy, Combination; Female; Fibromyalgia; Humans; Ibuprofen; Middle Aged	1992
Development of preliminary criteria for response to treatment in fibromyalgia syndrome. The Journal of rheumatology, 1991, Volume: 18, Issue:10 Topics: Amitriptyline; Double-Blind Method; Fibromyalgia; Humans; Naproxen; Regression Analysis	1991
The effects of cyclobenzaprine on sleep physiology and symptoms in patients with fibromyalgia. The Journal of rheumatology, 1991, Volume: 18, Issue:3 Topics: Adult; Affect; Amitriptyline; Double-Blind Method; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain; Sleep	1991
A randomized trial of cyclobenzaprine for the treatment of fibromyalgia. The Journal of rheumatology. Supplement, 1989, Volume: 19 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Fibromyalgia; Humans; Middle Aged; Pain Measurement; Palliative Care; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Sleep	1989
Acute back pain and spasm. A controlled multicenter trial of combined analgesic and antispasm agents. Spine, 1989, Volume: 14, Issue:4 Topics: Acute Disease; Amitriptyline; Back Pain; Diflunisal; Double-Blind Method; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Muscle Cramp; Muscle Relaxants, Central; Salicylates	1989
The plasma endorphin, prostaglandin and catecholamine profile of patients with fibrositis treated with cyclobenzaprine and placebo: a 5-month study. The Journal of rheumatology. Supplement, 1989, Volume: 19 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; beta-Endorphin; Catecholamines; Dinoprostone; Double-Blind Method; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Placebos; Sleep	1989
A review of the role of tricyclic medications in the treatment of fibromyalgia syndrome. The Journal of rheumatology. Supplement, 1989, Volume: 19 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biomechanical Phenomena; Clinical Trials as Topic; Fibromyalgia; Humans; Pain; Pain Measurement; Sleep; Syndrome	1989
Evaluating the efficacy of a combination therapy. Statistics in medicine, 1987, Volume: 6, Issue:6 Topics: Amitriptyline; Analgesics; Back Pain; Biometry; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Drug Combinations; Humans; Monte Carlo Method; Muscle Relaxants, Central; Random Allocation	1987
A comparison of cyclobenzaprine and placebo in the management of fibrositis. A double-blind controlled study. Arthritis and rheumatism, 1988, Volume: 31, Issue:12 Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Double-Blind Method; Female; Fibromyalgia; Humans; Male; Middle Aged; Muscle Relaxants, Central; Placebos; Random Allocation	1988
Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial. Arthritis and rheumatism, 1994, Volume: 37, Issue:1 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Double-Blind Method; Fibromyalgia; Humans; Pain Measurement; Patient Compliance; Placebos	1994
[Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia]. Minerva medica, 1994, Volume: 85, Issue:3 Topics: Adult; Amitriptyline; Drug Therapy, Combination; Female; Fibromyalgia; Fluoxetine; Humans; Middle Aged; Muscle Relaxants, Central; Time Factors	1994
Lack of sedative and cognitive effects of diphenhydramine and cyclobenzaprine in elderly volunteers. Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:4 Topics: Aged; Aged, 80 and over; Amitriptyline; Arousal; Cognition; Diphenhydramine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Tranquilizing Agents	1997
Cyclobenzaprine pharmacokinetics, including the effects of age, gender, and hepatic insufficiency. Journal of clinical pharmacology, 2002, Volume: 42, Issue:1 Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Analysis of Variance; Area Under Curve; Biological Availability; Confidence Intervals; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Muscle Relaxants, Central; Sex Factors	2002
The effectiveness of adding pharmacologic treatment with clonazepam or cyclobenzaprine to patient education and self-care for the treatment of jaw pain upon awakening: a randomized clinical trial. Journal of orofacial pain, 2002,Winter, Volume: 16, Issue:1 Topics: Adult; Amitriptyline; Clonazepam; Female; GABA Modulators; Health Education, Dental; Humans; Male; Muscle Relaxants, Central; Self Care; Sleep Wake Disorders; Temporomandibular Joint Dysfunction Syndrome; Treatment Outcome	2002
Cyclobenzaprine with ibuprofen versus ibuprofen alone in acute myofascial strain: a randomized, double-blind clinical trial. Annals of emergency medicine, 2003, Volume: 41, Issue:6 Topics: Adolescent; Adult; Aged; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Muscle Relaxants, Central; Myofascial Pain Syndromes; Pain Measurement; Spasm	2003
Efficacy of a low-dose regimen of cyclobenzaprine hydrochloride in acute skeletal muscle spasm: results of two placebo-controlled trials. Clinical therapeutics, 2003, Volume: 25, Issue:4 Topics: Acute Disease; Adult; Amitriptyline; Back Pain; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Muscle Relaxants, Central; Muscle, Skeletal; Neck Pain; Spasm; Treatment Outcome	2003
Low-dose cyclobenzaprine versus combination therapy with ibuprofen for acute neck or back pain with muscle spasm: a randomized trial. Current medical research and opinion, 2005, Volume: 21, Issue:9 Topics: Adolescent; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Muscle Relaxants, Central; Neck Pain; Spasm	2005
Single-dose pharmacokinetics of once-daily cyclobenzaprine extended release 30 mg versus cyclobenzaprine immediate release 10 mg three times daily in healthy young adults : a randomized, open-label, two-period crossover, single-centre study. Clinical drug investigation, 2008, Volume: 28, Issue:12 Topics: Adult; Amitriptyline; Cross-Over Studies; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Male; Muscle Relaxants, Central	2008
Comparison of the single-dose pharmacokinetics of once-daily cyclobenzaprine extended-release 30 mg and cyclobenzaprine immediate-release 10 mg three times daily in the elderly: a randomized, open-label, crossover study. Drugs & aging, 2009, Volume: 26, Issue:2 Topics: Aged; Aging; Amitriptyline; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Muscle Relaxants, Central; Therapeutic Equivalency; Time Factors	2009
Effect of food on the pharmacokinetics of once-daily cyclobenzaprine extended-release 30 mg: a randomized, open-label, crossover, single-centre study. Clinical drug investigation, 2009, Volume: 29, Issue:3 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Area Under Curve; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Female; Food-Drug Interactions; Half-Life; Humans; Male; Sample Size; Young Adult	2009
A pharmacokinetic comparison of single doses of once-daily cyclobenzaprine extended-release 15 mg and 30 mg: a randomized, double-blind, two-period crossover study in healthy volunteers. Clinical therapeutics, 2009, Volume: 31, Issue:1 Topics: Adolescent; Adult; Amitriptyline; Area Under Curve; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Half-Life; Humans; Male; Muscle Relaxants, Central; Young Adult	2009
Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: two randomized, double-blind, placebo-controlled studies of identical design. Current medical research and opinion, 2009, Volume: 25, Issue:5 Topics: Adolescent; Adult; Aged; Algorithms; Amitriptyline; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Relaxants, Central; Neck Pain; Placebos; Spasm; Treatment Outcome; Young Adult	2009
Bioavailability of a controlled-release cyclobenzaprine tablet and influence of a high fat meal on bioavailability. International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:4 Topics: Adult; Amitriptyline; Area Under Curve; Biological Availability; Cross-Over Studies; Delayed-Action Preparations; Dietary Fats; Food-Drug Interactions; Humans; Male; Muscle Relaxants, Central; Tablets; Young Adult	2009
Comparison of ibuprofen, cyclobenzaprine or both in patients with acute cervical strain: a randomized controlled trial. CJEM, 2010, Volume: 12, Issue:1 Topics: Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Muscle Relaxants, Central; Pain Measurement; Prospective Studies; Sprains and Strains; Trauma Centers; Treatment Outcome	2010
Efficacy and tolerability of cyclobenzaprine extended release for acute muscle spasm: a pooled analysis. Postgraduate medicine, 2010, Volume: 122, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Amitriptyline; Chi-Square Distribution; Delayed-Action Preparations; Double-Blind Method; Humans; Middle Aged; Muscle Relaxants, Central; Pain Measurement; Placebos; Spasm; Statistics, Nonparametric; Treatment Outcome; United States	2010
Steady-state pharmacokinetics of once-daily cyclobenzaprine extended release: a randomized, double-blind, 2-period crossover study in healthy volunteers. Clinical therapeutics, 2011, Volume: 33, Issue:6 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Area Under Curve; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; Humans; Male; Middle Aged; Young Adult	2011
Effects of bedtime very low dose cyclobenzaprine on symptoms and sleep physiology in patients with fibromyalgia syndrome: a double-blind randomized placebo-controlled study. The Journal of rheumatology, 2011, Volume: 38, Issue:12 Topics: Adult; Aged; Amitriptyline; Double-Blind Method; Electroencephalography; Fatigue; Female; Fibromyalgia; Humans; Male; Middle Aged; Placebos; Sleep; Sleep Wake Disorders; Treatment Outcome	2011
Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction. Journal of the American Dental Association (1939), 2011, Volume: 142, Issue:10 Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Double-Blind Method; Edema; Female; Follow-Up Studies; Humans; Male; Mandible; Molar, Third; Muscle Relaxants, Central; Pain Measurement; Pain, Postoperative; Placebos; Postoperative Complications; Premedication; Prospective Studies; Range of Motion, Articular; Tooth Extraction; Tooth, Impacted; Treatment Outcome; Trismus; Young Adult	2011
Chlorpromazine quantification in human plasma by UPLC-electrospray ionization tandem mass spectrometry. Application to a comparative pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Dec-01, Volume: 879, Issue:31 Topics: Adolescent; Adult; Amitriptyline; Area Under Curve; Biological Availability; Chlorpromazine; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Stability; Female; Humans; Limit of Detection; Linear Models; Male; Middle Aged; Random Allocation; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2011
Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study. Audiology & neuro-otology, 2012, Volume: 17, Issue:3 Topics: Adult; Aged; Amitriptyline; Clonidine; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Orphenadrine; Pilot Projects; Propiophenones; Severity of Illness Index; Tinnitus; Treatment Outcome	2012
Pharmacokinetics and bioequivalence evaluation of cyclobenzaprine tablets. BioMed research international, 2013, Volume: 2013 Topics: Amitriptyline; Antidepressive Agents; Chromatography, High Pressure Liquid; Depression; Half-Life; Healthy Volunteers; Humans; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; United States	2013
Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine. Journal of oral & facial pain and headache, 2014,Spring, Volume: 28, Issue:2 Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Clonidine; Double-Blind Method; Facial Pain; Female; Humans; Ibuprofen; Male; Middle Aged; Muscle Relaxants, Central; Pain Measurement; Patient Education as Topic; Placebos; Self Care; Severity of Illness Index; Sleep; Temporomandibular Joint Dysfunction Syndrome; Treatment Outcome; Young Adult	2014
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial. JAMA, 2015, Oct-20, Volume: 314, Issue:15 Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Treatment Outcome	2015
Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain. CJEM, 2016, Volume: 18, Issue:6 Topics: Acetaminophen; Acute Disease; Administration, Oral; Adult; Amitriptyline; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Emergency Service, Hospital; Female; Follow-Up Studies; Hospitals, Teaching; Humans; Low Back Pain; Male; Middle Aged; Naproxen; Oxycodone; Pain Measurement; Patient Satisfaction; Severity of Illness Index; Treatment Outcome; Young Adult	2016
Bioequivalence of cyclobenzaprine hydrochloride extended-release capsule taken intact or sprinkled over applesauce . International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:12 Topics: Adult; Amitriptyline; Capsules; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Male; Muscle Relaxants, Central; Therapeutic Equivalency	2017
An assessment of the centrally acting muscle relaxant tolperisone on driving ability and cognitive effects compared to placebo and cyclobenzaprine. Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:4 Topics: Adult; Amitriptyline; Automobile Driving; Cognition; Cross-Over Studies; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Psychomotor Performance; Self Report; Tolperisone	2020
Pain control following alloplastic breast reconstruction with muscle relaxant: A randomized controlled trial. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2021, Volume: 74, Issue:2 Topics: Adult; Amitriptyline; Drug Administration Schedule; Female; Humans; Mammaplasty; Middle Aged; Muscle Relaxants, Central; Pain, Postoperative; Treatment Outcome	2021
Randomized clinical trial of bedtime sublingual cyclobenzaprine (TNX-102 SL) in military-related PTSD and the role of sleep quality in treatment response. Psychiatry research, 2021, Volume: 301 Topics: Amitriptyline; Double-Blind Method; Humans; Military Personnel; Sleep; Stress Disorders, Post-Traumatic	2021

Other Studies

121 other study(ies) available for amitriptyline and cyclobenzaprine

Article	Year
Antiarrhythmic activity of amitriptyline analogues in conscious dogs after myocardial infarction: cyproheptadinium methiodide. Journal of medicinal chemistry, 1980, Volume: 23, Issue:11 Topics: Amitriptyline; Animals; Anti-Arrhythmia Agents; Cyproheptadine; Dogs; Hemodynamics; Myocardial Infarction	1980
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain. RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2 Topics:	2022
Determination of various drugs in rodent diet mixtures. Journal of chromatography, 1977, Jan-21, Volume: 131 Topics: Amitriptyline; Animal Feed; Animals; Benzylidene Compounds; Chromatography, Gas; Chromatography, Thin Layer; Dibenzocycloheptenes; Drug Stability; Halofenate; Indenes; Methods; Pharmaceutical Preparations; Rodentia; Spectrophotometry	1977
Behavioral effects of cyclobenzaprine. Proceedings of the Western Pharmacology Society, 1979, Volume: 22 Topics: Amitriptyline; Animals; Behavior, Animal; Dextroamphetamine; Female; Humans; Male; Mice; Mice, Inbred Strains; Motor Activity; Muscle Relaxants, Central; Pentobarbital; Rats; Sleep; Stereotyped Behavior	1979
Effects of cyclobenzaprine on interneurones of the spinal cord. Neuropharmacology, 1978, Volume: 17, Issue:7 Topics: Amitriptyline; Animals; Brain Stem; Cats; Decerebrate State; Dibenzocycloheptenes; Female; Interneurons; Male; Muscle Relaxants, Central; Reflex, Monosynaptic; Reticular Formation; Spinal Cord	1978
Cyclobenzaprine: effect on segmental monosynaptic and tonic vibration reflexes in the cat. Neuropharmacology, 1978, Volume: 17, Issue:9 Topics: Amitriptyline; Animals; Cats; Cerebellum; Decerebrate State; Dibenzocycloheptenes; Female; Male; Muscle Relaxants, Central; Reflex; Reflex, Monosynaptic; Spinal Cord; Vibration	1978
Identification of 10, 11-epoxide and other cyclobenzaprine metabolites isolated from rat urine. Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:6 Topics: Amitriptyline; Animals; Chromatography, Gas; Dibenzocycloheptenes; Epoxy Compounds; Ethers, Cyclic; Glucuronidase; Hydrolysis; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; Rats	1976
Gas-liquid chromatographic determination of nanogram amounts of cyclobenzaprine in plasma using a nitrogen detector. Journal of chromatography, 1976, Sep-01, Volume: 124, Issue:1 Topics: Amitriptyline; Chromatography, Gas; Chromatography, Liquid; Dibenzocycloheptenes; Humans; Microchemistry; Muscle Relaxants, Central; Nitrogen	1976
Effects of cyclobenzaprine on brainstem motor systems. Neuropharmacology, 1976, Volume: 15, Issue:10 Topics: Amitriptyline; Animals; Brain Stem; Cats; Diazepam; Dibenzocycloheptenes; Efferent Pathways; Evoked Potentials; Female; Male; Motor Neurons; Neural Inhibition; Physostigmine; Reflex, Monosynaptic; Reticular Formation; Synapses; Vestibular Nuclei	1976
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant. Neuropharmacology, 1975, Volume: 14, Issue:9 Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam; Dibenzocycloheptenes; Female; Male; Mice; Muscle Relaxants, Central; Muscle Rigidity; Rabbits; Seizures; Tachyphylaxis; Tetanus	1975
REMEDi drug profiling system readily distinguishes between cyclobenzaprine and amitriptyline in emergency toxicology urine specimens. Clinical chemistry, 1992, Volume: 38, Issue:11 Topics: Amitriptyline; Chromatography, High Pressure Liquid; Emergencies; Humans; Toxicology	1992
Fibromyalgia in children; diagnosis and treatment. The West Virginia medical journal, 1991, Volume: 87, Issue:3 Topics: Adolescent; Amitriptyline; Antidepressive Agents; Child; Diagnosis, Differential; Drug Therapy, Combination; Female; Fibromyalgia; Humans; Male; Muscle Relaxants, Central	1991
Overdose of cyclobenzaprine, the tricyclic muscle relaxant. Annals of emergency medicine, 1986, Volume: 15, Issue:5 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bicarbonates; Charcoal; Emergencies; Female; Humans; Ipecac; Muscle Relaxants, Central; Sodium; Sodium Bicarbonate; Therapeutic Irrigation	1986
Syndrome of imperforate oropharynx with costovertebral and auricular anomalies. American journal of medical genetics, 1989, Volume: 32, Issue:2 Topics: Abnormalities, Drug-Induced; Amitriptyline; Ear, External; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Oropharynx; Ribs; Syndrome; Thoracic Vertebrae; Tolmetin	1989
Pharmacotherapeutics in fibrositis. The American journal of medicine, 1986, Sep-29, Volume: 81, Issue:3A Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Drug Therapy, Combination; Fibromyalgia; Humans; Muscle Relaxants, Central; Psychotropic Drugs	1986
Detection of interference by cyclobenzaprine in liquid-chromatographic assays of tricyclic antidepressants. Clinical chemistry, 1987, Volume: 33, Issue:6 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Humans; Muscle Relaxants, Central; Spectrophotometry	1987
Interference by flexeril, a tricyclic muscle relaxant, with liquid-chromatographic determination of imipramine. Clinical chemistry, 1986, Volume: 32, Issue:8 Topics: Amitriptyline; Humans; Imipramine; Muscle Relaxants, Central	1986
Drugs in dentistry. Muscle relaxants. Dental management, 1985, Volume: 25, Issue:12 Topics: Amitriptyline; Carisoprodol; Humans; Methocarbamol; Muscle Relaxants, Central; Orphenadrine	1985
Cyclobenzaprine overdosage. Annals of internal medicine, 1985, Volume: 102, Issue:4 Topics: Amitriptyline; Chromatography, Gas; Humans; Oxazepam; Parasympatholytics; Pyrilamine	1985
Determination of cyclobenzaprine in plasma and urine using capillary gas chromatography with nitrogen-selective detection. Journal of chromatography, 1985, May-03, Volume: 339, Issue:2 Topics: Amitriptyline; Chromatography, Gas; Glucuronates; Humans; Kinetics; Tranquilizing Agents	1985
Cyclobenzaprine: effect on tonic vibration reflexes in local tetanus cat preparations. Neuropharmacology, 1984, Volume: 23, Issue:8 Topics: Amitriptyline; Animals; Cats; Decerebrate State; Electric Stimulation; Female; Male; Muscle Contraction; Muscle Relaxants, Central; Reflex; Spinal Cord; Tetanus Toxin; Vibration	1984
Mania in two patients following cyclobenzaprine. Psychosomatics, 1984, Volume: 25, Issue:10 Topics: Adult; Amitriptyline; Bipolar Disorder; Delusions; Female; Humans; Male	1984
Paradoxical diaphoresis in cyclobenzaprine poisoning. Annals of internal medicine, 1984, Volume: 101, Issue:6 Topics: Adult; Amitriptyline; Chromatography, Gas; Humans; Hyperhidrosis; Male	1984
Amitriptyline sensitization of a serotonin-mediated behavior depends on the passage of time and not repeated treatment. Life sciences, 1983, Oct-24, Volume: 33, Issue:17 Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Behavior, Animal; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Time Factors	1983
Cyclobenzaprine overdosage. Journal of toxicology. Clinical toxicology, 1983, Volume: 20, Issue:3 Topics: Adolescent; Adult; Amitriptyline; Female; Humans; Male; Physostigmine; Suicide, Attempted	1983
Predictive value of muscle relaxant models in rats and cats. Journal of pharmacological methods, 1983, Volume: 10, Issue:3 Topics: Amitriptyline; Animals; Benzodiazepines; Cats; Female; Male; Models, Biological; Morphine; Muscle Relaxants, Central; Rats; Rats, Inbred Strains; Reflex	1983
Psychosis following cyclobenzaprine use. The Journal of clinical psychiatry, 1983, Volume: 44, Issue:4 Topics: Adult; Amitriptyline; Bipolar Disorder; Female; Humans; Muscle Relaxants, Central; Psychoses, Substance-Induced; Spasm	1983
Cyclobenzaprine effects on locus coeruleus cells in tissue slice. Neuropharmacology, 1983, Volume: 22, Issue:2 Topics: Action Potentials; Amitriptyline; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Locus Coeruleus; Male; Norepinephrine; Rats; Rats, Inbred Strains	1983
Determination of cyclobenzaprine in tablets by high-performance liquid chromatography. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:6 Topics: Amitriptyline; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Spectrophotometry, Ultraviolet; Tablets	1982
The effects of cyclobenzaprine on locus coeruleus cells in vitro. Proceedings of the Western Pharmacology Society, 1982, Volume: 25 Topics: Amitriptyline; Animals; In Vitro Techniques; Locus Coeruleus; Male; Rats; Rats, Inbred Strains	1982
Cyclobenzaprine: a possible mechanism of action for its muscle relaxant effect. Canadian journal of physiology and pharmacology, 1981, Volume: 59, Issue:1 Topics: Amitriptyline; Animals; Electromyography; Electrophysiology; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Muscle Relaxants, Central; Norepinephrine; Rats; Spinal Cord	1981
Brainstem noradrenergic system depression by cyclobenzaprine. Neuropharmacology, 1980, Volume: 19, Issue:2 Topics: Amitriptyline; Animals; Axons; Brain Stem; Cats; Female; Locus Coeruleus; Male; Norepinephrine; Phenoxybenzamine; Reflex, Monosynaptic; Sympathetic Nervous System	1980
Cyclobenzaprine: studies on its site of muscle relaxant action in the cat. Neuropharmacology, 1980, Volume: 19, Issue:8 Topics: Amitriptyline; Animals; Brain Stem; Cats; Decerebrate State; Dose-Response Relationship, Drug; Muscle Contraction; Muscle Relaxation; Reflex; Reticular Formation; Spinal Cord; Vestibular Nerve; Vestibular Nucleus, Lateral	1980
Development and comparison of high-performance liquid chromatographic methods with tandem mass spectrometric and ultraviolet absorbance detection for the determination of cyclobenzaprine in human plasma and urine. Journal of chromatography. B, Biomedical applications, 1995, Apr-07, Volume: 666, Issue:1 Topics: Amitriptyline; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Muscle Relaxants, Central; Reproducibility of Results; Spectrophotometry, Ultraviolet	1995
Neuroleptic malignant-like syndrome due to cyclobenzaprine? Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:1 Topics: Adult; Amitriptyline; Humans; Male; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome	1995
Microbore liquid chromatography of tertiary amine anticholinergic pharmaceuticals with tris(2,2'-bipyridine)ruthenium(III) chemiluminescence detection. Journal of chromatographic science, 1995, Volume: 33, Issue:6 Topics: 2,2'-Dipyridyl; Amines; Amitriptyline; Atropine; Butanones; Cholinergic Antagonists; Chromatography, High Pressure Liquid; Cyclopentolate; Dicyclomine; Hydrogen-Ion Concentration; Indicators and Reagents; Luminescent Measurements; Organometallic Compounds; Procyclidine; Scopolamine	1995
Study on zwitter-ionization of drugs. II. Synthesis and pharmacological activity of some N-[3-(5H-dibenzo[a, d]cyclohepten-5-ylidene) propyl]-N-methylamino- and N-[3-(6H-dibenz[b, e]oxepin-11-ylidene) propyl]-N-methylamino-alkanoic acid derivatives and re Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:11 Topics: Amitriptyline; Animals; Biogenic Monoamines; Doxepin; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Molecular Structure; Muscle Relaxants, Central; Rabbits; Rats; Rats, Wistar; Receptors, Biogenic Amine; Receptors, Histamine H1; Structure-Activity Relationship	1993
A multiple drug intoxication involving cyclobenzaprine and ibuprofen. The American journal of forensic medicine and pathology, 1993, Volume: 14, Issue:3 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Fatal Outcome; Humans; Ibuprofen; Male; Mass Spectrometry; Suicide	1993
Cyclobenzaprine-induced delirium in two octogenarians. The Journal of clinical psychiatry, 1993, Volume: 54, Issue:1 Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Delirium; Female; Humans; Male; Muscle Relaxants, Central	1993
Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:7 Topics: Adult; Amitriptyline; Child; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Muscle Relaxants, Central; Recombinant Proteins; Tumor Cells, Cultured	1996
Response to "Neuroleptic malignant-like syndrome due to cyclobenzaprine?". Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:1 Topics: Adult; Amitriptyline; Catatonia; Humans; Lead Poisoning; Male; Neuroleptic Malignant Syndrome; Tranquilizing Agents	1996
Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. European journal of pharmacology, 1996, Sep-05, Volume: 311, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Amitriptyline; Animals; Decerebrate State; Fenclonine; Male; Muscle Relaxants, Central; Neural Pathways; Oxidopamine; Rats; Rats, Wistar; Reflex, Monosynaptic; Serotonin; Serotonin Agents; Sympathectomy, Chemical	1996
Formation of mammalian metabolites of cyclobenzaprine by the fungus, Cunninghamella elegans. Chemico-biological interactions, 1996, Oct-21, Volume: 102, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Chromatography, High Pressure Liquid; Fungi; Magnetic Resonance Spectroscopy; Microsomes, Liver; Oxygen; Oxygen Isotopes; Rats	1996
Nefazodone and neurotoxicity. The Journal of clinical psychiatry, 1997, Volume: 58, Issue:8 Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Carbamazepine; Cytochrome P-450 CYP2D6; Drug Interactions; Drug Therapy, Combination; Humans; Piperazines; Risperidone; Triazoles	1997
Drowning due to cyclobenzaprine and ethanol. Forensic science international, 1999, Mar-15, Volume: 100, Issue:1-2 Topics: Accidents, Home; Adult; Alcohol Drinking; Amitriptyline; Autopsy; Baths; Cause of Death; Drowning; Drug Synergism; Ethanol; Fatal Outcome; Female; Humans; Muscle Relaxants, Central	1999
Hallucinations in an elderly patient taking recommended doses of cyclobenzaprine. Archives of internal medicine, 2000, May-08, Volume: 160, Issue:9 Topics: Aged; Amitriptyline; Drug Interactions; Female; Hallucinations; Humans; Muscle Relaxants, Central	2000
Acute on chronic intestinal pseudoobstruction responds to neostigmine. Digestive diseases and sciences, 2000, Volume: 45, Issue:8 Topics: Acute Disease; Adult; Amitriptyline; Cholinergic Antagonists; Cholinesterase Inhibitors; Chronic Disease; Female; Humans; Intestinal Pseudo-Obstruction; Multiple Endocrine Neoplasia Type 2b; Neostigmine	2000
First episode psychosis following cyclobenzaprine use. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2000, Volume: 45, Issue:8 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Psychoses, Substance-Induced	2000
Cyclobenzaprine hydrochloride is a commonly prescribed centrally acting muscle relaxant, which is structurally similar to tricyclic antidepressants (TCAs) and differs from amitriptyline by only one double bond. The Clinical journal of pain, 2001, Volume: 17, Issue:1 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Drug Therapy, Combination; Humans; Male; Muscle Relaxants, Central; Nortriptyline; Pain	2001
Investigation of cyclobenzaprine hydrochloride release from oral osmotic delivery systems containing a water-swellable polymer. Drug development and industrial pharmacy, 2002, Volume: 28, Issue:6 Topics: Administration, Oral; Amitriptyline; Antidepressive Agents, Tricyclic; Drug Delivery Systems; Excipients; Humans; Osmotic Pressure; Polyethylene Glycols; Tablets	2002
Release of cyclobenzaprine hydrochloride from osmotically rupturable tablets. Drug development and industrial pharmacy, 2002, Volume: 28, Issue:6 Topics: Amitriptyline; Chemistry, Pharmaceutical; Excipients; Membranes, Artificial; Osmotic Pressure; Polyethylene Glycols; Tablets; Tranquilizing Agents	2002
The lack of a placebo effect in a trial of fluoxetine in the treatment of fibromyalgia. The American journal of medicine, 2002, Volume: 113, Issue:7 Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-Generation; Female; Fibromyalgia; Fluoxetine; Humans; Moclobemide; Placebo Effect; Randomized Controlled Trials as Topic; Treatment Outcome	2002
Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cyproheptadine; Decerebrate State; Dose-Response Relationship, Drug; Fenclonine; Indophenol; Ketanserin; Male; Rats; Rats, Wistar; Receptors, Serotonin; Reflex; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Synapses; Synaptic Transmission	2003
Fatal cyclobenzaprine overdose with postmortem values. Journal of forensic sciences, 2003, Volume: 48, Issue:4 Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Diazepam; Drug Overdose; Ethanol; Female; Humans; Male; Middle Aged; Molecular Structure; Muscle Relaxants, Central; Suicide	2003
Interactions of cyclobenzaprine and tricyclic antidepressants. The Journal of clinical psychiatry, 2005, Volume: 66, Issue:1 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Interactions; Humans; Male; Middle Aged; Nortriptyline; Pain; Sleep Initiation and Maintenance Disorders; Syncope	2005
Persistent low back pain. The New England journal of medicine, 2005, Sep-01, Volume: 353, Issue:9 Topics: Amitriptyline; Analgesics, Non-Narcotic; Chronic Disease; Humans; Low Back Pain; Muscle Relaxants, Central; Obesity; Weight Gain; Weight Loss	2005
Transient synovitis of the hip in an adult. Southern medical journal, 2006, Volume: 99, Issue:2 Topics: Acute Disease; Aged; Amitriptyline; Diagnosis, Differential; Drug Therapy, Combination; Follow-Up Studies; Glucocorticoids; Hip Joint; Humans; Magnetic Resonance Imaging; Male; Muscle Relaxants, Central; Prednisone; Range of Motion, Articular; Synovitis	2006
Efficacy and safety of acupuncture for the treatment of non-specific acute low back pain: a randomised controlled multicentre trial protocol [ISRCTN65814467]. BMC complementary and alternative medicine, 2006, Apr-21, Volume: 6 Topics: Acetaminophen; Acupuncture; Acute Disease; Adult; Amitriptyline; Analgesics; Bayes Theorem; Clinical Protocols; Cost-Benefit Analysis; Diclofenac; Humans; Ibuprofen; Low Back Pain; Multicenter Studies as Topic; Pain Measurement; Patient Satisfaction; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Sample Size; Treatment Outcome	2006
Serotonin syndrome from the interaction of cyclobenzaprine with other serotoninergic drugs. Anesthesia and analgesia, 2006, Volume: 103, Issue:6 Topics: Aged; Amitriptyline; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Phenelzine; Serotonin Syndrome; Thiophenes	2006
The control of impurities in amitriptyline hydrochloride using a reversed-phase hybrid stationary phase. Pharmeuropa scientific notes, 2005, Volume: 2005, Issue:1 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Dibenzocycloheptenes; Drug Contamination; Drug Stability; Mass Spectrometry; Molecular Structure; Reproducibility of Results; Temperature; Time Factors; Viscosity	2005
Extended-release cyclobenzaprine (Amrix). The Medical letter on drugs and therapeutics, 2007, Dec-17, Volume: 49, Issue:1276 Topics: Amitriptyline; Delayed-Action Preparations; Drug Interactions; Humans; Muscle Relaxants, Central; Spasm; Treatment Outcome	2007
Serotonin syndrome in a patient taking Lexapro and Flexeril: a case report. The American journal of emergency medicine, 2008, Volume: 26, Issue:9 Topics: Adult; Amitriptyline; Citalopram; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tranquilizing Agents	2008
Lower facial contouring with botulinum toxin type A. The Journal of craniofacial surgery, 2008, Volume: 19, Issue:6 Topics: Amitriptyline; Antimitotic Agents; Botulinum Toxins, Type A; Colchicine; Electromyography; Female; Follow-Up Studies; Humans; Hypertrophy; Injections, Intramuscular; Male; Masseter Muscle; Middle Aged; Muscle Contraction; Muscle Relaxants, Central; Neuromuscular Agents; Patient Satisfaction; Prospective Studies; Treatment Outcome	2008
Anticholinergic esotropia. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2008, Volume: 28, Issue:4 Topics: Accommodation, Ocular; Acetylcholine; Adult; Amitriptyline; Benztropine; Brain; Cholinergic Antagonists; Diplopia; Esotropia; Exotropia; Female; Humans; Hydroxyzine; Iatrogenic Disease; Mood Disorders; Neuromuscular Junction; Oculomotor Muscles	2008
Is there sufficient evidence to suggest cyclobenzaprine might be implicated in causing serotonin toxicity? The American journal of emergency medicine, 2009, Volume: 27, Issue:4 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Drug Overdose; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome	2009
Torticollis under cyclobenzaprine. Pharmacology, 2009, Volume: 84, Issue:2 Topics: Amitriptyline; Biperiden; Humans; Male; Muscarinic Antagonists; Muscle Relaxants, Central; Myoclonus; Torticollis; Young Adult	2009
Menstrual-related nummular headache. Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:4 Topics: Adult; Amitriptyline; Female; Headache; Humans; Menstrual Cycle; Muscle Relaxants, Central	2010
A 19-month-old girl with recurrent illness: over the hills and through the woods. Pediatric emergency care, 2009, Volume: 25, Issue:12 Topics: Amitriptyline; Drug Overdose; Female; Humans; Infant; Lethargy; Muscle Relaxants, Central; Psychomotor Disorders	2009
Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. The American journal of emergency medicine, 2011, Volume: 29, Issue:6 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Chi-Square Distribution; Coma; Drug Overdose; Female; Humans; Hypertension; Hypotension; Incidence; Male; Poison Control Centers; Retrospective Studies; Seizures; Sleep Stages; Texas	2011
Time to recovery in patients with acute painful musculoskeletal conditions treated with extended-release or immediate-release cyclobenzaprine. Advances in therapy, 2011, Volume: 28, Issue:4 Topics: Acute Disease; Administration, Oral; Adult; Amitriptyline; Delayed-Action Preparations; Disorders of Excessive Somnolence; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle, Skeletal; Pain; Patient Satisfaction; Recovery of Function; Spasm; Therapeutic Equivalency; Time Factors; Treatment Outcome	2011
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family. Arquivos de neuro-psiquiatria, 2011, Volume: 69, Issue:2B Topics: Adult; Amitriptyline; Baclofen; Female; Humans; Magnetic Resonance Imaging; Male; Muscle Relaxants, Central; Muscle Spasticity; Pedigree; Spinocerebellar Ataxias	2011
Linking pharmacology to clinical reports: cyclobenzaprine and its possible association with serotonin syndrome. Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:5 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Humans; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Receptors, Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Syndrome	2011
Integration of diverse data sources for prediction of adverse drug events. Clinical pharmacology and therapeutics, 2011, Volume: 90, Issue:5 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Humans; Serotonin Syndrome	2011
Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. The American journal of emergency medicine, 2012, Volume: 30, Issue:2 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Drug Overdose; Humans; Incidence; Poison Control Centers; Retrospective Studies	2012
Determination of cyclobenzaprine in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry and its application in a pharmacokinetic study. Biomedical chromatography : BMC, 2012, Volume: 26, Issue:9 Topics: Amitriptyline; Chromatography, Liquid; Citalopram; Drug Stability; Humans; Linear Models; Liquid-Liquid Extraction; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2012
Sleep as a window into the world of fibromyalgia syndrome. The Journal of rheumatology, 2011, Volume: 38, Issue:12 Topics: Amitriptyline; Female; Fibromyalgia; Humans; Male; Placebos; Sleep; Sleep Wake Disorders	2011
Treatment of tinnitus with cyclobenzaprine: an open-label study. International journal of clinical pharmacology and therapeutics, 2012, Volume: 50, Issue:5 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Tinnitus	2012
Serotonin syndrome in a patient with chronic pain polypharmacy. Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:8 Topics: Adult; Amitriptyline; Anti-Allergic Agents; Antidepressive Agents; Carisoprodol; Cetirizine; Chronic Pain; Duloxetine Hydrochloride; Female; Humans; Muscle Relaxants, Central; Narcotics; Polypharmacy; Serotonin Syndrome; Thiophenes; Tramadol	2014
Treatment of levator ani syndrome with cyclobenzaprine. The Annals of pharmacotherapy, 2012, Volume: 46, Issue:10 Topics: Adult; Amitriptyline; Anus Diseases; Humans; Male; Muscle Relaxants, Central; Pain	2012
Medications as a potential source of exposure to phthalates among women of childbearing age. Reproductive toxicology (Elmsford, N.Y.), 2013, Volume: 37 Topics: Adolescent; Adult; Amitriptyline; Drug Utilization; Environmental Exposure; Female; Humans; Mesalamine; Middle Aged; Omeprazole; Phthalic Acids; Pregnancy; Young Adult	2013
Suspected tricyclic antidepressant overdose successfully treated with lipids. Journal of emergency nursing, 2013, Volume: 39, Issue:3 Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Doxepin; Drug Overdose; Fat Emulsions, Intravenous; Humans; Male; Middle Aged; Trazodone; Treatment Outcome	2013
Neuropsychiatric side effects of cyclobenzaprine. BMJ case reports, 2013, May-02, Volume: 2013 Topics: Amitriptyline; Antidepressive Agents; Delirium; Humans; Male; Middle Aged; Movement Disorders; Muscle Relaxants, Central; Oxycodone; Pain; Serotonin Syndrome	2013
Intranasal delivery of cyclobenzaprine hydrochloride-loaded thiolated chitosan nanoparticles for pain relief. Journal of drug targeting, 2013, Volume: 21, Issue:8 Topics: Administration, Intranasal; Amitriptyline; Animals; Brain; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Epithelial Cells; Humans; Hyperalgesia; Mice; Nanoparticles; Pain; Permeability; Tissue Distribution	2013
Erythema multiforme vs. DRESS syndrome associated with the combined use of lamotrigine and cyclobenzaprine: a case report. International journal of psychiatry in medicine, 2012, Volume: 44, Issue:4 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antimanic Agents; Citalopram; Diagnosis, Differential; Drug Interactions; Drug Therapy, Combination; Eosinophilia; Erythema Multiforme; Female; Humans; Lamotrigine; Middle Aged; Off-Label Use; Selective Serotonin Reuptake Inhibitors; Syndrome; Triazines	2012
Maternal use of cyclobenzaprine (Flexeril) may induce ductal closure and persistent pulmonary hypertension in neonates. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2014, Volume: 27, Issue:11 Topics: Abnormalities, Drug-Induced; Amitriptyline; Antidepressive Agents, Tricyclic; Ductus Arteriosus; Female; Heart Septal Defects, Atrial; Heart Septal Defects, Ventricular; Humans; Infant, Newborn; Male; Maternal Exposure; Persistent Fetal Circulation Syndrome; Pregnancy; Ultrasonography	2014
Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment. Journal of the Association for Research in Otolaryngology : JARO, 2015, Volume: 16, Issue:2 Topics: Amitriptyline; Animals; Male; Noise; Rats; Rats, Sprague-Dawley; Reflex, Startle; Tinnitus	2015
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6 Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocardiography; Epilepsy; Female; Heart Arrest; Humans; Lacosamide; Levetiracetam; Piracetam; Risk Factors; Sodium Bicarbonate; Sodium Channel Blockers; Sodium Channels; Suicide, Attempted; Tachycardia, Ventricular; Treatment Outcome	2015
Use of an Intravascular Heat Exchange Catheter and Intravenous Lipid Emulsion for Hypothermic Cardiac Arrest After Cyclobenzaprine Overdose. Therapeutic hypothermia and temperature management, 2015, Volume: 5, Issue:3 Topics: Amitriptyline; Cardiopulmonary Bypass; Cardiopulmonary Resuscitation; Drug Overdose; Fat Emulsions, Intravenous; Heart Arrest; Humans; Hypothermia; Male; Pharmaceutical Solutions; Rewarming; Tranquilizing Agents; Treatment Outcome; Vascular Access Devices; Young Adult	2015
"Mom, You Have to Trust Me". JAMA internal medicine, 2015, Volume: 175, Issue:9 Topics: Aged, 80 and over; Amitriptyline; Cross Infection; Delirium; Fatal Outcome; Female; Humans; Medication Reconciliation; Unnecessary Procedures	2015
Comprehensive Duloxetine Analysis in a Fatal Overdose. Journal of analytical toxicology, 2016, Volume: 40, Issue:2 Topics: Aged; Alcoholism; Amitriptyline; Depression; Diphenhydramine; Drug Overdose; Duloxetine Hydrochloride; Fatal Outcome; Female; Humans; Selective Serotonin Reuptake Inhibitors	2016
Determination of Degradation Products of Cyclobenzaprine Hydrochloride, Lidocaine and Piroxicam in a Semi-Topical Formulation: MS-MS Confirmation of Unknown Impurities. Journal of chromatographic science, 2016, Volume: 54, Issue:6 Topics: Amitriptyline; Lidocaine; Piroxicam; Tandem Mass Spectrometry	2016
Variations in enzymatic hydrolysis efficiencies for amitriptyline and cyclobenzaprine in urine. Journal of analytical toxicology, 2016, Volume: 40, Issue:9 Topics: Amitriptyline; Calibration; Chromatography, High Pressure Liquid; Enzyme Activation; Glucuronidase; Glucuronides; Humans; Hydrolysis; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2016
Exudative Erythema Multiforme Due to Cyclobenzaprine. Journal of investigational allergology & clinical immunology, 2016, Volume: 26, Issue:4 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Erythema Multiforme; Female; Humans; Middle Aged	2016
PURLs: More isn't better with acute low back pain treatment. The Journal of family practice, 2016, Volume: 65, Issue:6 Topics: Acetaminophen; Amitriptyline; Drug Combinations; Female; Humans; Low Back Pain; Male; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Randomized Controlled Trials as Topic; Treatment Outcome	2016
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: Naproxen with Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo to Treating Acute Low Back Pain: A Randomized Clinical Trial. American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:6 Topics: Acetaminophen; Amitriptyline; Humans; Low Back Pain; Naproxen; Oxycodone; Peer Review; Physiatrists	2017
A Case of Ileus and ST Segment Elevation. Rhode Island medical journal (2013), 2016, Nov-01, Volume: 99, Issue:11 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Catheterization; Electrocardiography; Humans; Male; Middle Aged; ST Elevation Myocardial Infarction; Troponin	2016
A Previously Healthy Adolescent With Acute Encephalopathy and Decorticate Posturing. Pediatrics, 2017, Volume: 139, Issue:1 Topics: Acute Febrile Encephalopathy; Adolescent; Amitriptyline; Brain; Bupropion; Decerebrate State; Diagnosis, Differential; Emergency Service, Hospital; Female; Glasgow Coma Scale; Humans; Intensive Care Units, Pediatric; Interdisciplinary Communication; Intersectoral Collaboration; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Self Medication; Serotonin Syndrome; Suicide, Attempted; Tomography, X-Ray Computed; Venlafaxine Hydrochloride	2017
Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice. PLoS neglected tropical diseases, 2017, Volume: 11, Issue:1 Topics: Amitriptyline; Animals; Antiprotozoal Agents; Humans; Interferon-gamma; Interleukin-10; Interleukin-6; Leishmania infantum; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Parasite Load; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	2017
Urinary Concentrations of Topically Administered Pain Medications. Journal of analytical toxicology, 2017, Mar-01, Volume: 41, Issue:2 Topics: Administration, Oral; Administration, Topical; Amines; Amitriptyline; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Limit of Detection; Skin Absorption; Substance Abuse Detection	2017
Unresponsive Male. Annals of emergency medicine, 2017, Volume: 69, Issue:5 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brugada Syndrome; Drug Overdose; Electrocardiography; Humans; Male; Middle Aged; Suicide, Attempted; Tachycardia, Sinus; Unconsciousness	2017
Treatment of vismodegib-associated muscle cramps with cyclobenzaprine: A retrospective review. Journal of the American Academy of Dermatology, 2017, Volume: 77, Issue:6 Topics: Aged; Amitriptyline; Anilides; Female; Humans; Male; Middle Aged; Muscle Cramp; Muscle Relaxants, Central; Pyridines; Retrospective Studies	2017
Five modified classical least squares based models for stability indicating analysis of cyclobenzaprine HCl with its major degradation products: A comparative study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2018, Nov-05, Volume: 204 Topics: Amitriptyline; Chromatography, High Pressure Liquid; Drug Stability; Least-Squares Analysis; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	2018
Change in Pain Score after Administration of Analgesics for Lower Extremity Fracture Pain during Hospitalization. Pain management nursing : official journal of the American Society of Pain Management Nurses, 2019, Volume: 20, Issue:2 Topics: Adult; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents; Baclofen; Bones of Lower Extremity; Cohort Studies; Duloxetine Hydrochloride; Female; Fractures, Bone; Gabapentin; Hospitalization; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain Management; Pain Measurement; Pregabalin; Retrospective Studies	2019
Induction of Psychosis by Cyclobenzaprine. Psychopharmacology bulletin, 2018, 06-20, Volume: 48, Issue:4 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Borderline Personality Disorder; Female; Humans; Muscle Relaxants, Central; Psychoses, Substance-Induced; Tranquilizing Agents	2018
Multi-Spectroscopic Characterization of Human Serum Albumin Binding with Cyclobenzaprine Hydrochloride: Insights from Biophysical and International journal of molecular sciences, 2019, Feb-03, Volume: 20, Issue:3 Topics: Amitriptyline; Circular Dichroism; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Serum Albumin, Human; Spectrum Analysis; Thermodynamics	2019
Transfer of Cyclobenzaprine into Human Milk and Subsequent Infant Exposure. Journal of human lactation : official journal of International Lactation Consultant Association, 2019, Volume: 35, Issue:3 Topics: Adult; Amitriptyline; Breast Feeding; Diagnosis, Differential; Female; Humans; Infant, Newborn; Mass Spectrometry; Milk, Human; Muscle Relaxants, Central; Pain; Pregnancy; Prenatal Care	2019
Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis. Oral and maxillofacial surgery, 2019, Volume: 23, Issue:4 Topics: Amitriptyline; Dexamethasone; Edema; Humans; Molar, Third; Pain, Postoperative; Prospective Studies; Tooth Extraction; Tooth, Impacted; Trismus	2019
Green analytical chromatographic assay method for quantitation of cyclobenzaprine in tablets, spiked human urine and in-vitro dissolution test. Annales pharmaceutiques francaises, 2019, Volume: 77, Issue:5 Topics: Amitriptyline; Chromatography, High Pressure Liquid; Gastric Juice; Green Chemistry Technology; Guidelines as Topic; Humans; Limit of Detection; Micelles; Muscle Relaxants, Central; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solubility; Spectrophotometry, Ultraviolet; Tablets	2019
Storage of urine specimens in point of care (POC) urine drug testing cups reduces concentrations of many drugs. Clinica chimica acta; international journal of clinical chemistry, 2019, Volume: 499 Topics: Amitriptyline; Chromatography, Liquid; Drug Storage; Fentanyl; Flunitrazepam; Fluoxetine; Humans; Mass Spectrometry; Nortriptyline; Paroxetine; Point-of-Care Testing; Sertraline	2019
Treatment data from the Brazilian fibromyalgia registry (EpiFibro). Advances in rheumatology (London, England), 2020, 01-21, Volume: 60, Issue:1 Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Brazil; Cohort Studies; Combined Modality Therapy; Cross-Sectional Studies; Drug Therapy, Combination; Duloxetine Hydrochloride; Exercise; Female; Fibromyalgia; Health Education; Humans; Male; Middle Aged; Muscle Stretching Exercises; Pregabalin; Registries	2020
Treatment of comatose patient from cyclobenzaprine overdose with therapeutic plasma exchange. Journal of clinical apheresis, 2022, Volume: 37, Issue:3 Topics: Adolescent; Amitriptyline; Coma; Drug Overdose; Female; Humans; Plasma Exchange; Plasmapheresis	2022
The Skeletal Muscle Relaxer Cyclobenzaprine Is a Potent Non-Competitive Antagonist of Histamine H1 Receptors. The Journal of pharmacology and experimental therapeutics, 2022, Volume: 380, Issue:3 Topics: Amitriptyline; Animals; Humans; Mice; Muscle, Skeletal; Rats; Receptors, Histamine H1	2022
Enabling Quantitative Analysis of Surface Small Molecules for Exposomics and Behavioral Studies. Journal of the American Society for Mass Spectrometry, 2022, Mar-02, Volume: 33, Issue:3 Topics: Amitriptyline; Carnitine; Environmental Exposure; Environmental Monitoring; Glutamine; Humans; Workplace	2022
Does Flexeril Work? Utility of Muscle Relaxants in Lower Back Pain. The Journal of emergency medicine, 2022, Volume: 62, Issue:5 Topics: Amitriptyline; Humans; Low Back Pain; Muscles; Vasodilator Agents	2022
Comment on "Treatment of comatose patient from cyclobenzaprine overdose with therapeutic plasma exchange". Journal of clinical apheresis, 2022, Volume: 37, Issue:4 Topics: Amitriptyline; Coma; Drug Overdose; Humans; Plasma Exchange; Plasmapheresis	2022
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants. Neurology, 2022, 09-27, Volume: 99, Issue:13 Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort Studies; Humans; Hydrocodone; Methocarbamol; Narcotic Antagonists; Neuromuscular Agents; Opiate Overdose; Orphenadrine; Oxycodone; Prescriptions; Sepsis; Substance-Related Disorders	2022
Energy metabolism as a target for cyclobenzaprine: A drug candidate against Visceral Leishmaniasis. Bioorganic chemistry, 2022, Volume: 127 Topics: Adenosine Triphosphate; Amitriptyline; Animals; Antiprotozoal Agents; Energy Metabolism; Humans; Leishmania infantum; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Reactive Oxygen Species	2022