amitriptyline and clozapine

amitriptyline has been researched along with clozapine in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (13.43)	18.7374
1990's	12 (17.91)	18.2507
2000's	26 (38.81)	29.6817
2010's	18 (26.87)	24.3611
2020's	2 (2.99)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Chiang, GH; Unger, SH	1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP	1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR	1
Amlaiky, N; Hen, R; Plassat, JL	1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR	1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C	1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
McKinnon, RA; Miners, JO; Smith, PA; Sorich, MJ	1
Keserü, GM	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Kottke, T; Ligneau, X; Stark, H; von Coburg, Y; Weizel, L	1
Caron, G; Ermondi, G; Visentin, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Sen, S; Sinha, N	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Modestin, J; Petrin, A	1
Richelson, E	1
Kudrin, VS; Mineyeva, MF; Rayevsky, KS	1
Breyer, U; Villumsen, K	1
Gabriel, E; Küfferle, B; Lenz, G; Schuster, P	1
Copp, PJ; Lament, R; Tennent, TG	1
Cools, AR	1
Gross, G; Schümann, HJ	1
Rechlin, T	2
Hemmeter, U; Holsboer-Trachsler, E; Pöldinger, W; Seifritz, E	1
Eikelmann, B; Konrad, C; Schormair, C; Telger, K	1
Feuerstein, TJ; Fischer, W; Kiefer, G	1
Rosendaal, FR; Thomassen, R; Vandenbroucke, JP	1
Arolt, V; Kirchner, H; Peters, M; Rothermundt, M; Rudolf, S	1
Belova, MV; Lisovik, ZA; Livanov, AS; Luzhnikov, EA; Ostapenko, YN	1
Arora, M; Praharaj, SK	1
Bomsien, S; Skopp, G	1
Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM	1
Aggarwal, A; Garg, A; Jiloha, RC	1
Dickenson, ER; Drewes, JE; Khan, SJ; McDonald, JA; Stevens-Garmon, J	1
Dick, S; Keene, W; Swales, J; Temesi, D	1
Praharaj, SK; Simlai, J; Sinha, S	1
Hoti, F; Lähteenvuo, M; Mehtälä, J; Taipale, H; Tanskanen, A; Tiihonen, J; Vattulainen, P	1
Deckert, J; Hommers, LG; Menke, A; Samanski, L; Scherf-Clavel, M; Unterecker, S	1
Engel, R; Frey, R; Friedrich, ME; Grohmann, R; Kasper, S; Konstantinidis, A; Rabl, U; Seifert, J; Stübner, S; Toto, S; Winkler, D	1
Boscutti, A; Brambilla, P; Cereda, G; Enrico, P; Lazzaretti, M	1

Reviews

3 review(s) available for amitriptyline and clozapine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants]. International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:1 Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine	1976

Other Studies

64 other study(ies) available for amitriptyline and clozapine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity. Journal of medicinal chemistry, 1981, Volume: 24, Issue:3 Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship	1981
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular pharmacology, 1993, Volume: 43, Issue:3 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24 Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection	1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular pharmacology, 1993, Volume: 44, Issue:2 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity	1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor. Molecular pharmacology, 1997, Volume: 52, Issue:3 Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines	1997
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum. Molecular pharmacology, 1998, Volume: 54, Issue:3 Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium	1998
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
Pharmacophore and quantitative structure-activity relationship modeling: complementary approaches for the rationalization and prediction of UDP-glucuronosyltransferase 1A4 substrate selectivity. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Catalysis; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Substrate Specificity	2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics. Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2 Topics: Animals; Antipsychotic Agents; Cell Line; CHO Cells; Cricetinae; Cricetulus; Histamine Antagonists; Humans; Radioligand Assay; Receptors, Histamine H3	2009
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds. Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2 Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface	2014
Tricyclic antidepressants and histamine H1 receptors. Mayo Clinic proceedings, 1979, Volume: 54, Issue:10 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic	1979
The effect of neuroleptics on brain tyrosine hydroxylase. Annali dell'Istituto superiore di sanita, 1978, Volume: 14, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Brain; Clozapine; Fluphenazine; Haloperidol; Hypothalamus; Male; Promethazine; Rats; Tyrosine 3-Monooxygenase	1978
Measurement of plasma levels of tricylic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms. European journal of clinical pharmacology, 1976, Mar-22, Volume: 09, Issue:5-6 Topics: Amitriptyline; Chromatography, Thin Layer; Clozapine; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Perazine; Psychotropic Drugs; Spectrophotometry, Ultraviolet	1976
[Individual conditions of pharmacogenic confusion conditions. Comparison of amitriptyline and clozapine]. Psychiatria clinica, 1976, Volume: 9, Issue:1 Topics: Adult; Amitriptyline; Austria; Clozapine; Cognition Disorders; Confusion; Delusions; Dibenzazepines; Female; Humans; Male	1976
Amitriptyline in clozapine-induced sialorrhoea. The British journal of psychiatry : the journal of mental science, 1991, Volume: 159 Topics: Amitriptyline; Clozapine; Drug Administration Schedule; Humans; Schizophrenia; Sialorrhea	1991
The nucleus accumbens and antidepressants: modulation of ergometrine-induced hyperactivity by typical and atypical antidepressants and neuroleptics in rats. Psychopharmacology, 1987, Volume: 92, Issue:3 Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Clorgyline; Clozapine; Desipramine; Ergonovine; Male; Mianserin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sulpiride; Zimeldine	1987
Enhancement of noradrenaline release from rat cerebral cortex by neuroleptic drugs. Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 315, Issue:2 Topics: Amitriptyline; Animals; Antipsychotic Agents; Cerebral Cortex; Clozapine; Cocaine; In Vitro Techniques; Male; Norepinephrine; Promazine; Rats; Stimulation, Chemical	1980
[Effects of psychopharmacologic therapy on heart rate variation]. Der Nervenarzt, 1995, Volume: 66, Issue:9 Topics: Adult; Amitriptyline; Arrhythmias, Cardiac; Autonomic Nervous System; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Overdose; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Psychotropic Drugs; Schizophrenia	1995
Decreased R-R variation: a criterium for overdosage of tricyclic psychotropic drugs. Intensive care medicine, 1995, Volume: 21, Issue:7 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arrhythmias, Cardiac; Case-Control Studies; Clozapine; Doxepin; Drug Monitoring; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Substance Abuse Detection	1995
Chronic leukocytosis and neutrophilia caused by rehabilitation stress in a clozapine-treated patient. Pharmacopsychiatry, 1993, Volume: 26, Issue:3 Topics: Amitriptyline; Anti-Anxiety Agents; Benzodiazepines; Clozapine; Depressive Disorder; Humans; Leukocytosis; Male; Middle Aged; Neutrophils; Smoking; Stress, Psychological	1993
[Risperidone after clozapine in therapy refractory schizoaffective psychosis--a case report]. Psychiatrische Praxis, 1997, Volume: 24, Issue:2 Topics: Adult; Amitriptyline; Antipsychotic Agents; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Prognosis; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Treatment Outcome	1997
Effects of amitriptyline, amitriptylinoxide, doxepine and clozapine on N-methyl-D-aspartate-evoked release of [3H]-acetylcholine in rat caudatoputamen. Arzneimittel-Forschung, 1999, Volume: 49, Issue:10 Topics: Acetylcholine; Algorithms; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Caudate Nucleus; Chronic Disease; Clozapine; Doxepin; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Pain; Putamen; Rats; Rats, Wistar	1999
Antipsychotic drugs and venous thromboembolism. Lancet (London, England), 2000, Jul-15, Volume: 356, Issue:9225 Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Humans; Imipramine; Incidence; Thromboembolism; Venous Thrombosis	2000
The influence of typical and atypical neuroleptic drugs in the production of interleukin-2 and interferon-gamma in vitro. Neuropsychobiology, 2002, Volume: 46, Issue:4 Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Haloperidol; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-2; Schizophrenia	2002
Comparative assessment of blood and urine analyses in patients with acute poisonings by medical, narcotic substances and alcohol in clinical toxicology. Przeglad lekarski, 2005, Volume: 62, Issue:6 Topics: Acute Disease; Amitriptyline; Carbamazepine; Central Nervous System Agents; Clozapine; Ethanol; Female; Humans; Immunoenzyme Techniques; Male; Mass Spectrometry; Narcotics; Poisoning; Reproducibility of Results; Russia; Severity of Illness Index; Substance Abuse Detection; Substance-Related Disorders; Toxicology	2005
Amitriptyline for clozapine-induced nocturnal enuresis and sialorrhoea. British journal of clinical pharmacology, 2007, Volume: 63, Issue:1 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Drug Administration Schedule; Humans; Male; Nocturnal Enuresis; Sialorrhea	2007
An in vitro approach to potential methadone metabolic-inhibition interactions. European journal of clinical pharmacology, 2007, Volume: 63, Issue:9 Topics: Algorithms; Amitriptyline; Analgesics, Opioid; Atomoxetine Hydrochloride; Chromatography, Liquid; Citalopram; Clozapine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Isoenzymes; Kinetics; Methadone; Methylation; N-Methyl-3,4-methylenedioxyamphetamine; Oxidoreductases, N-Demethylating; Propylamines; Psychotropic Drugs; Pyridines; Pyrrolidines; Tandem Mass Spectrometry; Zolpidem	2007
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants. Psychopharmacology, 2007, Volume: 195, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine	2007
Trihexyphenidyl (benzhexol) in clozapine-induced nocturnal enuresis and sialorrhea. Indian journal of medical sciences, 2009, Volume: 63, Issue:10 Topics: Amitriptyline; Antipsychotic Agents; Clozapine; Humans; Male; Muscarinic Antagonists; Nocturnal Enuresis; Schizophrenia; Sialorrhea; Trihexyphenidyl; Young Adult	2009
Sorption of emerging trace organic compounds onto wastewater sludge solids. Water research, 2011, Volume: 45, Issue:11 Topics: Adsorption; Amitriptyline; Clozapine; Cosmetics; Household Products; Hydroxyzine; Organic Chemicals; Pharmaceutical Preparations; Risperidone; Sewage; Verapamil; Waste Disposal, Fluid; Water Pollutants, Chemical	2011
The stability of amitriptyline N-oxide and clozapine N-oxide on treated and untreated dry blood spot cards. Journal of pharmaceutical and biomedical analysis, 2013, Mar-25, Volume: 76 Topics: Amitriptyline; Animals; Chromatography, High Pressure Liquid; Clozapine; Dried Blood Spot Testing; Drug Monitoring; Drug Stability; Rats; Rats, Wistar; Time Factors	2013
Very Low Dose Amitriptyline for Clozapine-Associated Sialorrhea. Current drug safety, 2016, Volume: 11, Issue:3 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Humans; Male; Schizophrenia; Sialorrhea; Young Adult	2016
Pharmacological treatments and risk of readmission to hospital for unipolar depression in Finland: a nationwide cohort study. The lancet. Psychiatry, 2017, Volume: 4, Issue:7 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cohort Studies; Depressive Disorder; Depressive Disorder, Major; Female; Finland; Humans; Incidence; Lithium; Male; Middle Aged; Outcome Assessment, Health Care; Patient Readmission; Risk; Secondary Prevention; Severity of Illness Index	2017
Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2. International clinical psychopharmacology, 2019, Volume: 34, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Female; Glucuronosyltransferase; Humans; Male; Middle Aged; Mirtazapine; Nortriptyline; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Smoking; Venlafaxine Hydrochloride	2019
Incidence of Drug-Induced Delirium During Treatment With Antidepressants or Antipsychotics: A Drug Surveillance Report of German-Speaking Countries Between 1993 and 2016. The international journal of neuropsychopharmacology, 2022, 08-04, Volume: 25, Issue:7 Topics: Adverse Drug Reaction Reporting Systems; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Delirium; Humans; Incidence; Muscarinic Antagonists; Psychoses, Substance-Induced	2022
Amitriptyline for clozapine-induced hypersalivation: A case series. Schizophrenia research, 2022, Volume: 243 Topics: Amitriptyline; Antipsychotic Agents; Clozapine; Humans; Schizophrenia; Sialorrhea	2022