amitriptyline has been researched along with clomipramine in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (50.26) | 18.7374 |
| 1990's | 33 (16.92) | 18.2507 |
| 2000's | 32 (16.41) | 29.6817 |
| 2010's | 30 (15.38) | 24.3611 |
| 2020's | 2 (1.03) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Chiang, GH; Unger, SH | 1 |
| Anderson, VB; Geyer, HM; Kruse, H; Ong, HH; Profitt, JA; Wilker, JC | 1 |
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Dhawan, NS; Izadmehr, S; Kastrinsky, DB; Narla, G; Ohlmeyer, M; Sangodkar, J; Zaware, N | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Fromm, GH; Glass, JD | 1 |
| Delini-Stula, A; Radeke, E; Vassout, A | 1 |
| Lüllmann-Rauch, R; Scheid, D | 1 |
| Lüllmann-Rauch, R | 2 |
| Franz, DN; Sangdee, C | 1 |
| Frisch, W; Lüllmann-Rauch, R | 1 |
| Mishra, R; Sulser, F | 1 |
| Burgess, CD; Turner, P; Wadsworth, J | 1 |
| Kampman, R; Kuha, S; Nummikko-Pelkonen, A | 1 |
| Dujovne, CA; Ueda, I; Yasuhara, H | 1 |
| Briley, M; Langer, SZ; Raisman, R | 1 |
| van Kammen, DP; van Scheyen, JD | 1 |
| Asberg, M; Montgomery, SA | 1 |
| Lingjaerde, O | 2 |
| Allaria, E; Biondi, PA; Cazzullo, CL; Negri, F; Sacchetti, E; Smeraldi, E | 1 |
| Dürst, T; Glatt, A; Klebs, K; Koella, WP | 1 |
| Carasso, RL; Streifler, M; Yehuda, S | 1 |
| Albert, W; Klicpera, C; Strian, F | 2 |
| Asberg, M; Bertilsson, L; Mellström, B; Rollins, D; Sjöqvist, F; Träskman, L | 1 |
| Delini-Stula, A; Vassout, A | 2 |
| Leppäluoto, J; Linnoila, M; Ranta, T; Seppälä, T | 1 |
| Moyes, IC; Moyes, RB | 2 |
| Escande, M; Gayral, L; Golberger, E; Jarrige, A; Kulik, J | 1 |
| Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| Ashcroft, GW | 1 |
| Capstick, N | 1 |
| Krupp, P; Wesp, M | 1 |
| Oksenkrug, GF | 1 |
| Middelburg, ZT; van Scheyen, JD | 1 |
| Bertschy, G; Bizouard, P; Bonin, B; François, TH; Nezelof, S; Sechter, D; Vandel, B; Vandel, S | 1 |
| Askenasi, R; Leduc, D; Lheureux, P; Vranckx, M | 1 |
| Clissold, SP; Dechant, KL | 1 |
| Zhao, JP | 1 |
| Blanchi, M; De Conno, F; Panerai, AE; Ripamonti, C; Sacerdote, P; Ventafridda, V; Zecca, E | 1 |
| Bennett, GW; Lighton, C; Marsden, CA | 1 |
| Møller, SE | 1 |
| Lavoie, PA; Tiberi, M | 1 |
| Cohen, DL; Hanahoe, TH; Purcell, WM | 1 |
| Bryan, W; Fraser, AD; Isner, AF | 1 |
| Garreau, M; Magni, G; Orofiamma, B; Palminteri, R | 1 |
| Danti, S; Fermanian, J; Frances, H | 1 |
| De Potter, WP; Schoups, AA | 1 |
| Ferrari, C; Marmiroli, N; Puglisi, PP; Sabatini, MA; Tedeschi, F; Truzzi, G | 1 |
| Hölzl, G; Krüger, R; Kuss, HJ; Schefold, L | 2 |
| Barone, P; Cardone, G; Iovino, M; Monteleone, P; Steardo, L | 1 |
| Iri, H; Kanba, S; Kubo, H; Matsumoto, K; Yagi, G; Yuki, H | 1 |
| Briley, M; Moret, C | 1 |
| Brini, A; Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
| Ishikura, Y; Ono, H; Yokota, S | 1 |
| Bourhim, N; Cantau, P; Carydakis, C; Castanas, E; Giraud, P; Oliver, C | 1 |
| Cournoyer, J | 1 |
| Domínguez-Gil, A; Fernández de Gatta, MM; García, MJ; Gutierrez, JR; Tamayo, M | 1 |
| Grohmann, R; Hippius, H; Rüther, E; von Oefele, K | 1 |
| Baumann, P; Cuendet, C; Eap, CB | 1 |
| Mellerup, ET; Plenge, P | 1 |
| Conquy, T; Durand, A; Rop, PP; Viala, A | 1 |
| Anselmi, E; Sevilla, E; Villar, A | 1 |
| Cygielman, G; Modai, I; Rinsky, H | 1 |
| Ericsson, O; Nordin, C; Spina, E | 1 |
| Bareggi, SR; Bonaccorsi, A; Franco, R; Garattini, S; Morselli, PL; Mundo, AS; Riva, E | 1 |
| Balashova, MG; Lobova, EK; Smulevich, AB; Vorob'ev, VIu; Zavidovskaia, GI | 1 |
| Couper-Smartt, JD; Rodham, R | 1 |
| Dresse, A; Van Dorsser, W | 1 |
| Brown, WA; Haier, RJ; Qualls, CB | 2 |
| Pawłowski, L | 1 |
| Burkard, WP; Da Prada, M; Keller, HH | 1 |
| Hall, H; Lindbom, LO; Malatray, J; Ogren, SO | 1 |
| Abou-Saleh, MT; Coppen, A | 1 |
| Goyot, C; Grenier, J; Hug, R | 1 |
| Ellinwood, EH; France, RD; Krishnan, KR | 1 |
| Larsen, OB; Møller, SE | 1 |
| Gram, LF; Kragh-Sørensen, P; Kristensen, CB; Møller, M; Pedersen, OL; Thayssen, P | 1 |
| Herzog, DB | 1 |
| Agras, WS; Kraemer, HC | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Nakanishi, H; Shibata, S; Ueki, S; Watanabe, S | 1 |
| Carter, RB; Leander, JD | 1 |
| Boiardi, A; Bussone, G; Di Giulio, AM; Galva, MD; La Mantia, L; Mantegazza, P; Picotti, GB | 1 |
| Vinet, B | 1 |
| Briley, MS; Langer, SZ; Sette, M | 1 |
| Brown, WA; Qualls, CB | 1 |
| Ananth, J; Engelsmann, F; Pecknold, JC; van den Steen, N | 1 |
| Cicardo, VH; Osman Dick, G | 1 |
| Marsden, CA; Stolz, JF | 1 |
| Górka, Z; Kwiatek, H; Pawłowski, L | 1 |
| Bazán, E; Fuentes, JA; Galindo, A; Guillamón, A; Somoza, E; Valencia, A | 1 |
| Agnoli, A; Caratozzolo, P; Ciabatti, P; Martucci, N; Rulli, V; Sollecito, A | 1 |
| Frazer, A; Mendels, J; Savage, DD | 1 |
| Nielsen-Kudsk, F; Quist, S | 2 |
| Moyes, IC; Moyes, RB; Ray, RL | 1 |
| Snyder, S | 1 |
| Brodin, E; Brodin, K; Ogren, SO | 1 |
| Benfield, P; Harris, MG | 1 |
| Hulstijn, W; Pagen, M; van Hoof, JJ; van Mier, H | 1 |
| Bagheri, H; Berlan, M; Houin, G; Montastruc, JL; Picault, P; Schmitt, L | 1 |
| Potvin, JH; Souetre, E; Thomander, L; Tollefson, GD | 1 |
| Cai, B; Matsumoto, K; Ohta, H; Watanabe, H | 1 |
| Baumann, P; Bertschy, G; Bizouard, P; Bonin, B; Bouquet, S; Francois, T; Sechter, D; Vandel, S | 1 |
| Erjavec, F; Ferjan, I | 2 |
| Lozet, H; Martin, P; Monteban, H; Souêtre, E | 1 |
| Levering, SC; Loonen, AJ; Oostelbos, MC; Toll, PJ | 1 |
| Caram-Lelham, N; Persson, B; Sundelöf, LO | 1 |
| Burrows, GD; Kremer, CM | 1 |
| Gartside, SE; Sharp, T; Umbers, V | 1 |
| Kumazawa, T; Lee, XP; Sato, K; Suzuki, O | 1 |
| Bartolini, A; Capaccioli, S; Galeotti, N; Ghelardini, C; Nicolin, A; Quattrone, A | 1 |
| Wolfe, RM | 1 |
| Aymard, G; Diquet, B; Livi, P; Pham, YT | 1 |
| Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA | 1 |
| Eriksson, T; Wålinder, J | 1 |
| Asbun, J; Castillo, C; Castillo, EF; Ocharan, ME; Valencia, I | 1 |
| Dodman, NH; Moon-Fanelli, AA; Sawyer, LS | 1 |
| Graham, BG; Sattely-Miller, EA; Schiffman, SS; Suggs, MS | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Roos, P | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Pinto, D | 1 |
| Akechi, T; Kugaya, A; Nakano, T; Okamura, H; Shima, Y; Uchitomi, Y | 1 |
| Jonasson, B; Jonasson, U; Saldeen, T | 1 |
| Antonietti, M; Denis, P; Ducrotte, P; Lalaude, O; Leroi, AM; Menard, JF; Touchais, JY | 1 |
| Dunham, AE; Ohad, DG; Overall, KL; Reich, MR | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C | 3 |
| Gsell, W; Jungkun, G; Kuss, HJ | 1 |
| Barańczyk-Kuźma, A; Jagiełło, J; Kuźma, M; Sawicki, J | 1 |
| Dunham, AE; Overall, KL | 1 |
| Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM | 1 |
| Nagaraja, MR; Sharada, S; Subhash, MN; Vinod, KY | 1 |
| Miyaoka, H; Shibuya, A; Suzuki, E; Yoshida, Y | 1 |
| Barańczyk-Kuźma, A; Gutowicz, M; Kaźmierczak, B; Kuźma, M; Sawicki, J | 1 |
| He, L; Wu, B; Zhou, M | 1 |
| Akechi, T; Akizuki, N; Ito, T; Nakano, T; Okamura, M; Shimizu, K; Uchitomi, Y | 1 |
| Bårdstu, KF; Ho, TS; Jönsson, JA; Pedersen-Bjergaard, S; Rasmussen, KE | 1 |
| Nika, MK; Papadoyannis, IN; Samanidou, VF | 1 |
| Alves, C; Fernandes, C; Lanças, FM; Rodrigues, JC; Santos-Neto, AJ | 1 |
| Burger, R; Deckert, J; Gerlach, M; Gonska, S; Jabs, B; Pfuhlmann, B; Riederer, P; Unterecker, S | 1 |
| Mosekilde, L; Rejnmark, L; Vestergaard, P | 1 |
| Cai, Y; Ruan, J; Tang, Y; Xiong, C | 1 |
| Booth-Genthe, CL; Grimm, SW; Guo, J; Linnenbach, AJ; Zhou, D | 1 |
| Higgins, SC; Pilkington, GJ | 1 |
| de Vos, A; Loovers, HM; van der Weide, J | 1 |
| Brenner, M; Cho, W; Messing, A; Peters, N | 1 |
| Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhou, M | 1 |
| Dalmizrak, O; Kulaksiz-Erkmen, G; Ozer, N | 1 |
| Naqvi, AZ; Rub, MA | 1 |
| Allilaire, JF; Couturier, PL; Goldwirt, L; Lambrey, S; Warot, D; Zahr, N | 1 |
| Amberger-Murphy, V; Cree, IA; Glaysher, S; Hurren, J; Knight, LA; McCormick, D; Parker, KA; Pilkington, GJ; Suovouri, A | 1 |
| Abdel-Zaher, AO; Farghaly, HS; Kotb, HI; Mostafa, MG | 1 |
| Maaswinkel, H; Weng, W; Zhu, L | 1 |
| Kaur, K; Malik, AK | 1 |
| Ferjan, I; Lipnik-Štangelj, M | 1 |
| Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M | 1 |
| Ishikawa, M; Maekawa, K; Murayama, M; Nakatsu, N; Saito, K; Saito, Y; Senoo, Y; Urata, M; Yamada, H | 1 |
| Derry, S; Hearn, L; Moore, RA; Phillips, T; Wiffen, PJ | 1 |
| Aldington, D; Derry, S; Moore, RA; Wiffen, PJ | 1 |
| Berm, EJJ; Brummel-Mulder, E; Hak, E; Maring, JG; Paardekooper, J; Wilffert, B | 1 |
| Arco, L | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Calabresi, P; Di Gregorio, M; Paolini Paoletti, F; Parnetti, L | 1 |
| Goodwin, GM; Joas, E; Jonsson, L; Landén, M; Pålsson, E; Smedler, E; Viktorin, A | 1 |
17 review(s) available for amitriptyline and clomipramine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Drug Evaluation; Drug Tolerance; Humans; Imipramine; Paroxetine; Piperidines; Serotonin Antagonists | 1991 |
Tryptophan to competing amino acids ratio in depressive disorder: relation to efficacy of antidepressive treatments.
Topics: Amino Acids; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Humans; Hydroxyindoleacetic Acid; Imipramine; Lithium; Metabolic Clearance Rate; Norepinephrine; Serotonin; Tryptophan; Tyrosine | 1985 |
Tryptophan and tyrosine availability: relation to clinical response to antidepressive pharmacotherapy.
Topics: Amitriptyline; Antidepressive Agents; Clomipramine; Depressive Disorder; Humans; Imipramine; Lithium; Prognosis; Tryptophan; Tyrosine | 1984 |
Plasma level monitoring of antidepressants: theoretical basis and clinical application.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Genetic Variation; Humans; Imipramine; Kinetics; Nortriptyline; Oxidation-Reduction; Patient Compliance; Pharmacogenetics | 1984 |
Pharmacotherapy of anorexia nervosa and bulimia.
Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs | 1984 |
Antidepressants and the serotonin uptake in platelets.
Topics: Amitriptyline; Antidepressive Agents; Blood Platelets; Brain; Clomipramine; Depression; Dose-Response Relationship, Drug; Humans; Serotonin; Serotonin Antagonists; Smoking | 1980 |
Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in older patients with depressive illness.
Topics: Aged; Amitriptyline; Clomipramine; Depressive Disorder; Drug Interactions; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Receptors, Adrenergic; Suicide | 1995 |
Mirtazapine: clinical advantages in the treatment of depression.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Feeding and Eating Disorders; Humans; Mianserin; Mirtazapine; Sleep Stages; Weight Gain | 1997 |
Antidepressant withdrawal reactions.
Topics: Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanols; Drug Administration Schedule; Female; Humans; Male; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome; Trazodone; Venlafaxine Hydrochloride | 1997 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia | 2006 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia | 2011 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia | 2013 |
Desipramine for neuropathic pain in adults.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desipramine; Diabetic Neuropathies; Fluoxetine; Humans; Middle Aged; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2014 |
Nortriptyline for neuropathic pain in adults.
Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Morphine; Neuralgia; Nortriptyline; Pregabalin; Randomized Controlled Trials as Topic | 2015 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
13 trial(s) available for amitriptyline and clomipramine
| Article | Year |
|---|---|
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Clomipramine; Depression; Desipramine; Dibenzazepines; Double-Blind Method; Drug Interactions; Female; Guanethidine; Heart Rate; Humans; Hydralazine; Hypertension; Male; Mianserin; Propranolol | 1978 |
Tricyclic antidepressants in the treatment of depressions. A double-blind clinical comparison of clomipramine (Anafranil) and amitriptyline.
Topics: Adult; Aged; Ambulatory Care; Amitriptyline; Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Fatigue; Female; Humans; Male; Middle Aged; Xerostomia | 1978 |
Clomipramine-induced mania in unipolar depression.
Topics: Adult; Age Factors; Aged; Amitriptyline; Bipolar Disorder; Brain Chemistry; Clomipramine; Depression; Dibenzazepines; Dopamine; Female; Humans; Male; Middle Aged; Serotonin; Time Factors | 1979 |
Clomipramine and amitriptyline in the treatment of severe pain.
Topics: Adult; Aged; Amitriptyline; Clomipramine; Female; Headache; Humans; Male; Middle Aged; Neuralgia; Pain, Intractable; Trigeminal Neuralgia | 1979 |
Fengabine, a new GABAmimetic agent in the treatment of depressive disorders: an overview of six double-blind studies versus tricyclics.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Chlorophenols; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Random Allocation | 1989 |
Pharmacotherapy of anorexia nervosa and bulimia.
Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs | 1984 |
The treatment of anorexia nervosa: do different treatments have different outcomes?
Topics: Adolescent; Amitriptyline; Anorexia Nervosa; Behavior Therapy; Body Weight; Clinical Trials as Topic; Clomipramine; Combined Modality Therapy; Female; Humans; Insulin; Levodopa; Lithium; Lithium Carbonate; Prognosis | 1984 |
Double-blind comparative study of clomipramine and amitriptyline in obsessive neurosis.
Topics: Adult; Amitriptyline; Anxiety Disorders; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Random Allocation | 1981 |
Pharmacokinetic study of yohimbine and its pharmacodynamic effects on salivary secretion in patients treated with tricyclic antidepressants.
Topics: Administration, Oral; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Norepinephrine; Salivation; Yohimbine | 1994 |
Fluvoxamine and fluoxetine: interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients.
Topics: Adult; Amitriptyline; Antipsychotic Agents; Clomipramine; Depressive Disorder; Drug Interactions; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Pharmacogenetics; Phenotype | 1995 |
Influence of heparin on the assay of amitriptyline, clomipramine, and their metabolites.
Topics: Amitriptyline; Anticoagulants; Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Edetic Acid; Female; Heparin; Humans; Lithium; Male; Middle Aged | 1996 |
Long-term effects of tricyclic antidepressants on norepinephrine kinetics in humans.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Blood Pressure; Brain; Brain Chemistry; Clomipramine; Depression; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Female; Heart Rate; Humans; Kinetics; Male; Middle Aged; Norepinephrine | 2001 |
Nitric oxide involvement in depression during interferon-alpha therapy.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Hepatitis C, Chronic; Humans; Imipramine; Interferon-alpha; Male; Nitrates; Nitric Oxide; Nitrites; Reference Values | 2003 |
166 other study(ies) available for amitriptyline and clomipramine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Novel tetracyclic spiropiperidines. 1. 3-Aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidines] as potential antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Tricyclic; Blepharoptosis; Chemical Phenomena; Chemistry; Drug Synergism; Male; Mice; Physostigmine; Piperidines; Spiro Compounds; Tetrabenazine | 1981 |
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Reengineered tricyclic anti-cancer agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dibenzazepines; Heterocyclic Compounds, 3-Ring; Humans; Mice; Neoplasms; Phenothiazines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Transplantation, Heterologous; Vesicular Monoamine Transport Proteins | 2015 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
The effect of tricyclic antidepressants on corticofugal inhibition of the spinal trigeminal nucleus.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brompheniramine; Cats; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Drug Combinations; Imipramine; Neural Inhibition; Procyclidine; Spinal Cord; Trigeminal Nerve | 1977 |
Some aspects of the psychopharmacological activity of maprotiline (Ludiomil): effects of single and repeated treatments.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Anthracenes; Behavior, Animal; Body Temperature; Clomipramine; Depression, Chemical; Escape Reaction; Haplorhini; Head; Imipramine; Maprotiline; Mice; Muscle Contraction; Phenobarbital; Propranolol; Rats; Reserpine; Shrews | 1978 |
Intraalveolar foam cells associated with lipidosis-like alterations in lung and liver of rats treated with tricyclic psychotropic drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Endoplasmic Reticulum; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Liver; Macrophages; Male; Pulmonary Alveoli; Rats; Thioridazine | 1975 |
Retinal lipidosis in albino rats treated with chlorphentermine and with tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorphentermine; Clomipramine; Female; Imipramine; Inclusion Bodies; Iprindole; Male; Microscopy, Electron; Phagocytosis; Phentermine; Rats; Retina | 1976 |
Enhancement of central norepinephrine and 5-hydroxytryptamine transmission by tricyclic antidepressants. A comparison.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Electric Stimulation; Female; Imipramine; Male; Norepinephrine; Serotonin; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Time Factors | 1979 |
Differential effects of chloroquine and of several other amphiphilic cationic drugs upon rat choroid plexus.
Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Choroid Plexus; Clomipramine; Female; Hexestrol; Inclusion Bodies; Iprindole; Male; Microscopy, Electron; Quinacrine; Rats | 1979 |
Role of serotonin reuptake inhibition in the development of subsensitivity of the norepinephrine (NE) receptor coupled adenylate cyclase system.
Topics: Adenylyl Cyclases; Amitriptyline; Animals; Brain; Clomipramine; Dibenzazepines; Fluoxetine; Male; Norepinephrine; Propylamines; Rats; Serotonin | 1978 |
Relationship between surface activity and toxicity to Chang liver cultures of tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cells, Cultured; Clomipramine; Doxepin; Glucuronidase; Humans; Imipramine; L-Lactate Dehydrogenase; Liver; Nortriptyline; Surface Tension | 1979 |
High-affinity 3H-imipramine binding in rat cerebral cortex.
Topics: Amitriptyline; Animals; Binding Sites; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; In Vitro Techniques; Male; Rats | 1979 |
A new depression scale designed to be sensitive to change.
Topics: Adolescent; Adult; Aged; Amitriptyline; Clomipramine; Depression; England; Female; Humans; Male; Maprotiline; Mianserin; Middle Aged; Psychiatric Status Rating Scales; Psychometrics; Sweden | 1979 |
Inhibition of platelet uptake of serotonin in plasma from patients treated with clomipramine and amitriptyline.
Topics: Adult; Aged; Amitriptyline; Blood Platelets; Clomipramine; Dibenzazepines; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Serotonin | 1979 |
3-Methoxy-4-hydroxyphenylglycol and primary depression: clinical and pharmacological considerations.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Clomipramine; Depression; Female; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged | 1979 |
Epileptic phenomena induced in the cat by the antidepressants maprotiline, imipramine, clomipramine, and amitriptyline.
Topics: Amitriptyline; Animals; Anthracenes; Cats; Cerebral Cortex; Clomipramine; Electroencephalography; Evoked Potentials; Female; Hippocampus; Imipramine; Male; Maprotiline; Reticular Formation; Seizures | 1979 |
Effects of somatic treatments on mood in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clomipramine; Depression; Desipramine; Electroconvulsive Therapy; Emotions; Evaluation Studies as Topic; Female; Humans; Male; Maprotiline; Middle Aged; Psychological Tests; Time Factors | 1979 |
Intraindividual similarity in the metabolism of amitriptyline and chlorimipramine in depressed patients.
Topics: Amitriptyline; Clomipramine; Dealkylation; Depression; Humans; Kinetics | 1979 |
Antidepressive treatment and mood swing patterns in endogenous depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clomipramine; Depression; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Male; Maprotiline; Middle Aged; Schizophrenia | 1979 |
Modulation of dopamine-mediated behavioural responses by antidepressants: effects of single and repeated treatment.
Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Clomipramine; Dopamine; Humans; Hydroxydopamines; Imipramine; Male; Maprotiline; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1979 |
Serum gonadotropin and TSH levels after tricyclic antidepressants in healthy males.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Doxepin; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Nortriptyline; Secretory Rate; Thyrotropin | 1977 |
Metabolism and pharmacokinetics of clomipramine. Measurement of plasma antidepressant levels by high-performance liquid chromatography.
Topics: Amitriptyline; Chromatography, Gas; Chromatography, High Pressure Liquid; Clomipramine; Dibenzazepines; Humans; Nortriptyline | 1977 |
[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Electroencephalography; Epilepsy; Female; History of Medicine; Humans; Imipramine; Male; Middle Aged; Seizures | 1976 |
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Flupenthixol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pilot Projects; Thioxanthenes; Trimipramine | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
Psychological medicine. Management of depression.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Clomipramine; Depression; Drug Interactions; Electroconvulsive Therapy; Female; Grief; Humans; Imipramine; Life Style; Lithium; Male; Phenelzine; Physician-Patient Relations; Recurrence; Social Isolation | 1975 |
Depressive reactions in the course of clomipramine therapy used in the treatment of obsessional conditions.
Topics: Adult; Aged; Amitriptyline; Clomipramine; Depression; Dibenzazepines; Female; Flupenthixol; Humans; Male; Obsessive-Compulsive Disorder; Schizophrenia | 1975 |
Inhibition of prostaglandin synthetase by psychotropic drugs.
Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
[Mania complicating treatment of unipolar vital depression].
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Clomipramine; Depression; Dibenzazepines; Female; Humans; Male; Middle Aged | 1975 |
Tricyclic antidepressant plasma levels after fluoxetine addition.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged | 1992 |
Risks of flumazenil in mixed benzodiazepine-tricyclic antidepressant overdose: report of a preliminary study in the dog.
Topics: Amitriptyline; Animals; Clomipramine; Dogs; Drug Overdose; Female; Flumazenil; Male; Risk Factors | 1992 |
[A control study of clomipramine and amitriptyline for treating obsessive-compulsive disorder].
Topics: Adolescent; Adult; Amitriptyline; Clomipramine; Female; Humans; Male; Obsessive-Compulsive Disorder | 1991 |
Studies on the effects of antidepressant drugs on the antinociceptive action of morphine and on plasma morphine in rat and man.
Topics: Amitriptyline; Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Drug Synergism; Humans; Morphine; Nortriptyline; Rats; Rats, Inbred Strains; Trazodone | 1990 |
Increase in levels and ex vivo release of thyrotrophin-releasing hormone (TRH) in specific regions of the CNS of the rat by chronic treatment with antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Central Nervous System; Clomipramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Metergoline; Mianserin; Rats; Rats, Inbred Strains; Serotonin; Thyrotropin-Releasing Hormone | 1985 |
Inhibition of fast axonal transport in bullfrog nerves by dibenzazepine and dibenzocycloheptadiene calmodulin inhibitors.
Topics: Acetylcholinesterase; Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Calmodulin; Clomipramine; Desipramine; Ganglia, Spinal; Imipramine; In Vitro Techniques; Microtubules; Phosphocreatine; Rana catesbeiana; Spinal Nerves | 1986 |
Contribution of post-secretory mechanisms to the observed pattern of histamine and 5-hydroxytryptamine secretion from peritoneal rat mast cells in response to compound 48/80.
Topics: Amitriptyline; Animals; Biological Transport; Cell Separation; Clomipramine; Female; Fluoxetine; Histamine; Histamine Release; Mast Cells; Nialamide; Pargyline; Peritoneal Cavity; Phosphatidylserines; Rats; Rats, Inbred Strains; Secretory Rate; Serotonin; Temperature | 1989 |
Evaluation of the EMIT amitriptyline and nortriptyline assays for the determination of serum clomipramine and desmethylclomipramine.
Topics: Amitriptyline; Antibody Specificity; Clomipramine; Cross Reactions; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Nortriptyline | 1989 |
Effect of tricyclic antidepressant drugs in the isolation-induced social behavioural deficit test.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Reference Values; Social Behavior; Social Isolation | 1989 |
Species dependence of adaptations at the pre- and postsynaptic serotonergic receptors following long-term antidepressant drug treatment.
Topics: Adaptation, Physiological; Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Imipramine; Male; Mianserin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Serotonin; Synaptic Transmission | 1988 |
Relationship between growth inhibition and mitochondrial function in petite-negative yeasts. II. Effects of central nervous system drugs upon pathogenic and non-pathogenic Candida species.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Candida; Cell Division; Chlorpheniramine; Chlorpromazine; Clomipramine; Cytochromes; Electrophoresis, Polyacrylamide Gel; Imipramine; Mitochondria; Oxygen Consumption; Promazine | 1985 |
Influence of neuroleptics on the metabolism of tricyclic antidepressants--in vitro experiments with rat liver microsomes.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Drug Interactions; Female; Haloperidol; Imipramine; In Vitro Techniques; Microsomes, Liver; Perazine; Rats; Rats, Inbred Strains | 1986 |
Is the dexamethasone suppression test predictive of response to specific antidepressant treatment in major depression?
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Clomipramine; Depressive Disorder; Dexamethasone; Female; Humans; Male; Maprotiline; Middle Aged; Neurotransmitter Agents | 1987 |
Automated determination of drugs in serum by column-switching high-performance liquid chromatography. IV. Separation of tricyclic and tetracyclic antidepressants and their metabolites.
Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Clomipramine; Humans; Hydrogen-Ion Concentration; Maprotiline; Nortriptyline; Quality Control; Regression Analysis | 1989 |
High- and low-affinity binding of [3H]imipramine in rat hypothalamus.
Topics: Amitriptyline; Animals; Citalopram; Clomipramine; Cyclopropanes; Hypothalamus; Imipramine; Kinetics; Male; Milnacipran; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Sodium | 1986 |
A role for serotonin and beta-endorphin in the analgesia induced by some tricyclic antidepressant drugs.
Topics: 5-Hydroxytryptophan; Amitriptyline; Analgesia; Animals; Antidepressive Agents, Tricyclic; beta-Endorphin; Clomipramine; Endorphins; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Cardiovascular effects of paroxetine, a newly developed antidepressant, in anesthetized dogs in comparison with those of imipramine, amitriptyline and clomipramine.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents; Atrioventricular Node; Blood Pressure; Clomipramine; Dogs; Electrocardiography; Female; Heart Conduction System; Heart Rate; Hemodynamics; Imipramine; Male; Paroxetine; Piperidines; Respiration | 1987 |
[Direct interaction of tricyclic antidepressants with opiate binding sites in the bovine adrenal medulla].
Topics: Adrenal Medulla; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cattle; Clomipramine; Cyproheptadine; Imipramine; Kinetics; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Comparison of the metabolism of the three antidepressants amitriptyline, imipramine, and chlorimipramine in vitro in rat liver microsomes.
Topics: Amitriptyline; Animals; Chemical Phenomena; Chemistry; Clomipramine; Female; Hydroxylation; Imipramine; In Vitro Techniques; Methylation; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1986 |
[Rapid response of a disorder to the addition of lithium carbonate: panic resistant to tricyclic antidepressants].
Topics: Adult; Amitriptyline; Anxiety Disorders; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Fear; Female; Humans; Lithium; Lithium Carbonate; Panic | 1986 |
High levels of tricyclic antidepressants in conventional therapy: determinant factors.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Risk Factors | 1988 |
[Adverse drug reactions in combined treatment with tricyclic antidepressants and monoamine oxidase inhibitors].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Risk Factors; Tranylcypromine | 1988 |
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine | 1988 |
Chlorimipramine--but not imipramine--rapidly reduces [3H]imipramine binding in human platelet membranes.
Topics: Amitriptyline; Blood Platelets; Cell Membrane; Clomipramine; Depressive Disorder; Humans; Imipramine; In Vitro Techniques; Kinetics | 1986 |
Determination of citalopram, amitriptyline and clomipramine in plasma by reversed-phase high-performance liquid chromatography.
Topics: Amitriptyline; Chromatography, High Pressure Liquid; Citalopram; Clomipramine; Humans; Propylamines; Serotonin Antagonists; Spectrophotometry, Ultraviolet | 1985 |
Effects of chlorpromazine and the antidepressant drugs amitriptyline, clomipramine and mianserin on the Ca-depleted rat uterus.
Topics: Amitriptyline; Animals; Antidepressive Agents; Calcium; Chlorpromazine; Clomipramine; Edetic Acid; Female; Mianserin; Oxytocin; Rats; Rats, Inbred Strains; Uterine Contraction | 1985 |
The DST as a predictor of acute response to treatment with ECT, chlorimipramine, amitriptyline, and phenelzine.
Topics: Amitriptyline; Clomipramine; Depressive Disorder; Dexamethasone; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Male; Personality Inventory; Phenelzine; Probability | 1986 |
Analysis of tricyclic antidepressants in serum and plasma yields similar results.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dealkylation; Humans; Nortriptyline | 1985 |
Lipidosis-like ultrastructural alterations in rat lymph nodes after treatment with tricyclic antidepressants or neuroleptics.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Lymph Nodes; Lymphocytes; Male; Microscopy, Electron; Rats; Thioridazine | 1974 |
Relationships between tricyclic antidepressant concentrations, 1-3H-noradrenaline uptake and chronotropic effect in isolated rat atria.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Radioisotopes; Chromatography, Thin Layer; Clomipramine; Dealkylation; Desipramine; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Female; Heart Atria; Heart Rate; Norepinephrine; Nortriptyline; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors; Tritium | 1974 |
[Problems of differentiated thymoleptic therapy in phasic depressions].
Topics: Adolescent; Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Azocines; Benzoates; Benzofurans; Bipolar Disorder; Clomipramine; Cyclothymic Disorder; Depression; Dibenzazepines; Dimethylamines; Dothiepin; Humans; Imipramine; Methylamines; Middle Aged; Personality Disorders; Propylamines; Schizophrenia | 1974 |
A technique for surveying side-effects of tricyclic drugs with reference to reported sexual effects.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Drug Evaluation; Erectile Dysfunction; Female; Humans; Imipramine; Libido; Male; Middle Aged; Orgasm; Sexual Behavior; Surveys and Questionnaires | 1973 |
[Comparative effects of various antidepressants on the response to noradrenaline of the deferent canal and the arterial pressure, and the response to 5-hydroxytryptamine of the rat uterus].
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Clomipramine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Orphenadrine; Quinuclidines; Rats; Serotonin; Uterus; Vas Deferens | 1974 |
Dexamethasone suppression test identifies subtypes of depression which respond to different antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Depression, Chemical; Desipramine; Dexamethasone; Diagnosis, Differential; Female; Humans; Imipramine; Male; Pituitary-Adrenal System | 1980 |
Amitriptyline and femoxetine, but not clomipramine or citalopram, antagonize hyperthermia induced by directly acting 5-hydroxytryptamine-like drugs in heat adapted rats.
Topics: Adaptation, Physiological; Amitriptyline; Animals; Body Temperature; Citalopram; Clomipramine; Dose-Response Relationship, Drug; Hot Temperature; Male; Piperazines; Piperidines; Propylamines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1984 |
Tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Imipramine; Male; Rats; Receptors, Dopamine; Time Factors | 1980 |
Cardiovascular and anticholinergic effects of zimelidine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Brompheniramine; Clomipramine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Imipramine; Male; Pyridines; Receptors, Cholinergic; Zimeldine | 1982 |
Classification of depression and response to antidepressive therapies.
Topics: Amitriptyline; Clomipramine; Combined Modality Therapy; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Zimeldine | 1983 |
[Radioimmunoassay of clomipramine and amitriptyline. Monitoring plasma levels of clomipramine in endogenous depression].
Topics: Amitriptyline; Clomipramine; Depressive Disorder; Humans; Radioimmunoassay | 1983 |
Tricyclic-induced akathisia in patients taking conjugated estrogens.
Topics: Adult; Akathisia, Drug-Induced; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Doxepin; Drug Interactions; Estrogens, Conjugated (USP); Female; Humans; Middle Aged | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
Effects of chronic administration of antidepressants on mouse-killing behavior (muricide) in olfactory bulbectomized rats.
Topics: Aggression; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorpromazine; Clomipramine; Desipramine; Diazepam; Humans; Injections; Male; Microinjections; Olfactory Bulb; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists | 1984 |
Platelet met-enkephalin immunoreactivity and 5-hydroxytryptamine concentrations in migraine patients: effects of 5-hydroxytryptophan, amitriptyline and chlorimipramine treatment.
Topics: 5-Hydroxytryptophan; Adult; Amitriptyline; Blood Platelets; Clomipramine; Enkephalin, Methionine; Female; Humans; Male; Middle Aged; Migraine Disorders; Serotonin | 1984 |
Column deactivation in analysis for underivatized tricyclic antidepressants by gas chromatography with use of a nitrogen detector.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Humans; Imipramine; Nitrogen; Nortriptyline | 1983 |
Complex inhibition of [3H]imipramine binding by serotonin and nontricyclic serotonin uptake blockers.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1983 |
Pituitary-adrenal disinhibition in depression: marker of a subtype with characteristic clinical features and response to treatment?
Topics: Adult; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Pituitary-Adrenal System; Recurrence | 1981 |
[Pressor response to the stimulation of peripheral sympathetic nerves and the posterior hypothalamus in the presence of tricyclic antidepressive agents and nomifensine in dogs].
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Clomipramine; Dogs; Electric Stimulation; Hypothalamus; Hypothalamus, Posterior; Imipramine; Isoquinolines; Nomifensine; Peripheral Nerves | 1982 |
The effects of antidepressants on aggressiveness induced by social deprivation in mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Imipramine; Maprotiline; Mice; Social Isolation | 1981 |
Withdrawal from chronic treatment with metergoline, dl-propranolol and amitriptyline enhances serotonin receptor mediated behaviour in the rat.
Topics: Amitriptyline; Animals; Behavior, Animal; Clomipramine; Ergolines; Humans; Iprindole; Male; Metergoline; Methoxydimethyltryptamines; Motor Activity; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Substance Withdrawal Syndrome | 1982 |
The dexamethasone suppression test in the identification subtypes of depression differentially responsive to antidepressants [proceedings].
Topics: Adult; Age Factors; Aged; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Radioimmunoassay; Statistics as Topic | 1981 |
Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors?
Topics: Amitriptyline; Animals; Clomipramine; Hindlimb; Imipramine; Lysergic Acid Diethylamide; Male; Quipazine; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Spinal Cord | 1981 |
Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Synaptosomes; Viloxazine | 1981 |
[The problem of side-effects: cardiotoxicity (author's transl)].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dibenzocycloheptenes; Double-Blind Method; Electrocardiography; Female; Heart Diseases; Humans; Male; Mianserin; Middle Aged | 1981 |
Monoamine oxidase inhibitors and serotonin uptake inhibitors: differential effects on [3H]serotonin binding sites in rat brain.
Topics: Amitriptyline; Animals; Binding Sites; Brain; Cerebral Cortex; Clomipramine; Clorgyline; Hippocampus; Male; Membranes; Monoamine Oxidase Inhibitors; Nialamide; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors | 1980 |
Myocardial pharmacokinetics of amitriptyline and clomipramine in the isolated, perfused rabbit heart.
Topics: Amitriptyline; Animals; Clomipramine; Half-Life; Kinetics; Myocardium; Perfusion; Rabbits; Time Factors | 1980 |
Effects of amitriptyline and clomipramine in the isolated, perfused rabbit heart.
Topics: Amitriptyline; Animals; Clomipramine; Coronary Circulation; Electrocardiography; Heart; Heart Rate; Hemodynamics; Myocardial Contraction; Oxygen Consumption; Perfusion; Rabbits | 1980 |
Some factors affecting the plasma levels of tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Delayed-Action Preparations; Drug Administration Schedule; Erythrocytes; Female; Humans; Ileum; Male; Middle Aged; Nortriptyline | 1980 |
Plasma levels and clinical improvement--a comparative study of clomipramine and amitriptyline in depression.
Topics: Amitriptyline; Clomipramine; Depression; Female; Humans; Male; Nortriptyline | 1980 |
Amitriptyline therapy of obsessive-compulsive neurosis.
Topics: Adult; Amitriptyline; Brain; Clomipramine; Female; Humans; Obsessive-Compulsive Disorder; Serotonin | 1980 |
Clomipramine and clonazepam increase cholecystokinin levels in rat ventral tegmental area and limbic regions.
Topics: Amitriptyline; Animals; Cholecystokinin; Clomipramine; Clonazepam; Infusion Pumps, Implantable; Limbic System; Male; Nortriptyline; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P; Ventral Tegmental Area | 1994 |
Figure drawing and psychomotor retardation: preliminary report.
Topics: Adult; Amitriptyline; Antipsychotic Agents; Clomipramine; Depressive Disorder; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Personality Inventory; Psychomotor Disorders; Psychomotor Performance; Reaction Time | 1993 |
Comorbid anxious signs and symptoms in major depression: impact on functional work capacity and comparative treatment outcomes.
Topics: Absenteeism; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Clomipramine; Comorbidity; Cost of Illness; Cross-Sectional Studies; Depressive Disorder; Dose-Response Relationship, Drug; Female; Fluoxetine; Humans; Male; Middle Aged; Personality Inventory; Work Capacity Evaluation | 1993 |
Biphasic effects of typical antidepressants and mianserin, an atypical antidepressant, on aggressive behavior in socially isolated mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Clomipramine; Male; Maprotiline; Mianserin; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha; Selective Serotonin Reuptake Inhibitors; Social Isolation; Yohimbine | 1993 |
Changes in histamine and serotonin secretion from rat peritoneal mast cells caused by antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Calcium; Clomipramine; Fluoxetine; Histamine Release; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneum; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin | 1996 |
Characteristics of the inhibitory effect of tricyclic antidepressants on histamine release from rat peritoneal mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Buffers; Calcium; Clomipramine; Desipramine; Histamine Release; Imipramine; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Structure-Activity Relationship | 1996 |
Quality of life in depressed patients: comparison of fluoxetine and major tricyclic antidepressants.
Topics: Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Fluoxetine; France; Humans; Male; Middle Aged; Quality of Life; Retrospective Studies; Selective Serotonin Reuptake Inhibitors | 1996 |
Polyelectrolyte/amphiphile interaction studied by surface tension measurements.
Topics: Adsorption; Amitriptyline; Carrageenan; Clomipramine; Doxepin; Electrolytes; Hydrogen-Ion Concentration; Osmolar Concentration; Salts; Structure-Activity Relationship; Surface Tension; Time Factors | 1996 |
Inhibition of 5-HT cell firing in the DRN by non-selective 5-HT reuptake inhibitors: studies on the role of 5-HT1A autoreceptors and noradrenergic mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amitriptyline; Animals; Clomipramine; Cyclohexanols; Male; Neurons; Paroxetine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Venlafaxine Hydrochloride | 1997 |
Detection of tricyclic antidepressants in whole blood by headspace solid-phase microextraction and capillary gas chromatography.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Humans; Imipramine; Male; Rats; Rats, Wistar; Sodium Hydroxide; Trimipramine; Water | 1997 |
Blockade of clomipramine and amitriptyline analgesia by an antisense oligonucleotide to mKv1.1, a mouse Shaker-like K+ channel.
Topics: Amitriptyline; Animals; Brain Chemistry; Clomipramine; Male; Mice; Molecular Sequence Data; Motor Activity; Oligonucleotides, Antisense; Pain Measurement; Pain Threshold; Polymerase Chain Reaction; Potassium Channels; RNA, Messenger; Sequence Homology; Virulence Factors, Bordetella | 1997 |
Sensitive and rapid method for the simultaneous quantification of five antidepressants with their respective metabolites in plasma using high-performance liquid chromatography with diode-array detection.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Fluoxetine; Humans; Imipramine; Maprotiline; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1997 |
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity | 1998 |
Amitriptyline and clomipramine increase the concentration of administered L-tryptophan in the rat brain.
Topics: Amino Acids; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Brain; Clomipramine; Male; Rats; Rats, Sprague-Dawley; Tryptophan | 1998 |
A study of the interactions of tricyclic antidepressants with alpha 1-adrenoceptor subtypes in rat aorta and caudal arteries.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Arteries; Clomipramine; Dose-Response Relationship, Drug; Drug Interactions; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1998 |
Psychogenic alopecia in cats: 11 cases (1993-1996).
Topics: Alopecia; Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Breeding; Buspirone; Cat Diseases; Cats; Clomipramine; Data Collection; Female; Grooming; Male; Retrospective Studies; Stress, Physiological | 1999 |
Effect of psychotropic drugs on taste responses in young and elderly persons.
Topics: Adult; Aged; Aging; Amitriptyline; Clomipramine; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Psychotropic Drugs; Taste; Trifluoperazine | 1998 |
Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Molecular Structure; Nortriptyline | 1998 |
On-line nonaqueous capillary electrophoresis and electrospray mass spectrometry of tricyclic antidepressants and metabolic profiling of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Calibration; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Mass Spectrometry; Molecular Structure | 1998 |
Milnacipran: new preparation. Tricyclics remain first-line antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclopropanes; Drug Evaluation; Europe; Fluoxetine; Fluvoxamine; Humans; Imipramine; Meta-Analysis as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; United States | 1998 |
Successful antidepressant treatment for five terminally ill cancer patients with major depression, suicidal ideation and a desire for death.
Topics: Affect; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Attitude to Death; Clomipramine; Cognition Disorders; Depressive Disorder; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Male; Middle Aged; Neoplasms; Psychomotor Agitation; Suicide Prevention; Suicide, Assisted; Survival Rate; Terminally Ill | 1999 |
Among fatal poisonings dextropropoxyphene predominates in younger people, antidepressants in the middle aged and sedatives in the elderly.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Autopsy; Azabicyclo Compounds; Clomipramine; Dextropropoxyphene; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Male; Middle Aged; Narcotics; Phenothiazines; Piperazines; Poisoning; Trimeprazine | 2000 |
Prolonged stationary colonic motility recording in seven patients with severe constipation secondary to antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Cathartics; Cholinergic Antagonists; Clomipramine; Colon; Colonoscopy; Constipation; Depressive Disorder; Eating; Fecal Impaction; Female; Gastrointestinal Motility; Humans; Male; Manometry; Maprotiline; Middle Aged; Mood Disorders; Muscle Contraction; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiazepines; Viloxazine | 2000 |
Electrocardiographic assessment of antianxiety medication in dogs and correlation with serum drug concentration.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Clomipramine; Dog Diseases; Dogs; Electrocardiography; Fluorescence Polarization Immunoassay; Statistics, Nonparametric | 2000 |
Involvement of potassium channels in amitriptyline and clomipramine analgesia.
Topics: Amitriptyline; Analgesia; Animals; Antidepressive Agents, Tricyclic; Calcium; Clomipramine; Injections, Intraventricular; Kv1.1 Potassium Channel; Male; Mice; Motor Activity; Pain Threshold; Postural Balance; Potassium Channels; Potassium Channels, Voltage-Gated; Reaction Time | 2001 |
Amitriptyline and clomipramine activate Gi-protein signaling pathway in the induction of analgesia.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Mice; Oligonucleotides, Antisense; Pain Measurement; Signal Transduction | 2002 |
[Tricyclic antidepressants as inhibitors of brain glutathione-S-transferase].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autopsy; Binding Sites; Brain; Clomipramine; Depressive Disorder; Doxepin; Glutathione Transferase; Humans; Imipramine | 2001 |
Role of Gi proteins in the antidepressant-like effect of amitriptyline and clomipramine.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Brain Chemistry; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Male; Mice; Motor Activity; Motor Skills; Oligonucleotides, Antisense; Pertussis Toxin; Postural Balance; Proto-Oncogene Proteins | 2002 |
Clinical features and outcome in dogs and cats with obsessive-compulsive disorder: 126 cases (1989-2000).
Topics: Age of Onset; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior Therapy; Behavior, Animal; Breeding; Cat Diseases; Cats; Clomipramine; Dog Diseases; Dogs; Female; Male; Obsessive-Compulsive Disorder; Retrospective Studies; Sex Factors; Treatment Outcome | 2002 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Imipramine; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sertraline; Trazodone | 2003 |
Cortical alpha-adrenoceptor downregulation by tricyclic antidepressants in the rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Down-Regulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Glutathione S-transferase pi as a target for tricyclic antidepressants in human brain.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Doxepin; Glutathione S-Transferase pi; Humans; Imipramine; Isoenzymes; Kinetics; Oxidation-Reduction | 2004 |
Clinical experience of the use of a pharmacological treatment algorithm for major depressive disorder in patients with advanced cancer.
Topics: Adult; Aged; Algorithms; Alprazolam; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Central Nervous System Stimulants; Clomipramine; Depressive Disorder, Major; Disease Progression; Drug Therapy, Combination; Female; Humans; Male; Methylphenidate; Middle Aged; Neoplasm Staging; Neoplasms; Prognosis; Severity of Illness Index | 2008 |
Supported liquid membranes in hollow fiber liquid-phase microextraction (LPME)--practical considerations in the three-phase mode.
Topics: Amitriptyline; Chromatography, High Pressure Liquid; Clomipramine; Dibenzazepines; Doxepin; Drug Stability; Drug Storage; Membranes, Artificial; Mianserin | 2007 |
Development of an HPLC method for the monitoring of tricyclic antidepressants in biofluids.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Clomipramine; Doxepin; Drug Monitoring; Humans; Imipramine; Models, Chemical; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry; Time Factors; Urinalysis | 2007 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Chromatography, Liquid; Clomipramine; Desipramine; Humans; Imipramine; Nortriptyline; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2007 |
Therapeutic drug monitoring of tricyclic antidepressants in everyday clinical practice.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male; Middle Aged; Reference Values; Retrospective Studies; Sex Factors; Treatment Outcome | 2007 |
Selective serotonin reuptake inhibitors and other antidepressants and risk of fracture.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Second-Generation; Case-Control Studies; Child; Child, Preschool; Clomipramine; Denmark; Depression; Dose-Response Relationship, Drug; Female; Fractures, Bone; Humans; Infant; Male; Middle Aged; Registries; Risk Factors; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2008 |
Extraction and determination of some psychotropic drugs in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography.
Topics: Amitriptyline; Calibration; Chromatography, High Pressure Liquid; Clomipramine; Drug Combinations; Drug Stability; Drug Storage; Female; Freezing; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Psychotropic Drugs; Reference Standards; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Thioridazine; Time Factors | 2009 |
Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biocatalysis; Clomipramine; Enzyme Inhibitors; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Sapogenins; Trimipramine | 2010 |
The in vitro effects of tricyclic drugs and dexamethasone on cellular respiration of malignant glioma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cell Respiration; Clomipramine; Dexamethasone; Doxepin; Humans; Oxygen Consumption; Respiratory Rate; Tumor Cells, Cultured | 2010 |
Association between CYP2C19*17 and metabolism of amitriptyline, citalopram and clomipramine in Dutch hospitalized patients.
Topics: Adolescent; Adult; Aged; Alleles; Amitriptyline; Aryl Hydrocarbon Hydroxylases; Biomarkers, Pharmacological; Citalopram; Clomipramine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Dose-Response Relationship, Drug; Female; Genetic Association Studies; Humans; Male; Middle Aged; Netherlands; Polymorphism, Genetic | 2011 |
Drug screening to identify suppressors of GFAP expression.
Topics: Amitriptyline; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Astrocytes; Cells, Cultured; Clomipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Humans; Luciferases; Mice; Mice, Transgenic; Microscopy, Fluorescence; Promoter Regions, Genetic; Time Factors | 2010 |
The inhibition characteristics of human placental glutathione S-transferase-π by tricyclic antidepressants: amitriptyline and clomipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dinitrochlorobenzene; Enzyme Assays; Female; Glutathione; Glutathione S-Transferase pi; Humans; Kinetics; Placenta; Pregnancy | 2011 |
Effects of pharmaceutical excipients on cloud points of amphiphilic drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Clomipramine; Cyclodextrins; Excipients; Fatty Acids; Imipramine; Phase Transition; Salts; Surface-Active Agents; Temperature | 2011 |
Therapeutic drug monitoring of clomipramine and amitriptyline in a depressed patient with upper digestive tract resection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Drug Monitoring; Drug Resistance; Female; Humans; Middle Aged; Upper Gastrointestinal Tract | 2011 |
The effect of tricyclic antidepressants on cutaneous melanoma cell lines and primary cell cultures.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cell Line, Tumor; Clomipramine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Melanoma; Nortriptyline; Primary Cell Culture; Skin Neoplasms | 2012 |
Comparative evaluation of the effect of tricyclic antidepressants on inducible nitric oxide synthase expression in neuropathic pain model.
Topics: Amitriptyline; Analgesics; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Cerebellum; Clomipramine; Desipramine; Enzyme Inhibitors; Gene Expression; Guanidines; Hippocampus; Immunohistochemistry; Male; Neuralgia; Nitric Oxide Synthase Type II; Pain Measurement; Rats; Rats, Wistar; RNA, Messenger; Sciatic Nerve | 2012 |
The immediate and the delayed effects of buspirone on zebrafish (Danio rerio) in an open field test: a 3-D approach.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Analysis of Variance; Animals; Anti-Anxiety Agents; Buspirone; Clomipramine; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Imaging, Three-Dimensional; Movement; Selective Serotonin Reuptake Inhibitors; Time Factors; Zebrafish | 2012 |
Study on the fluorescence quenching reaction of amitriptyline and clomipramine hydrochlorides with eosin Y and its analytical application.
Topics: Absorption; Amitriptyline; Buffers; Calibration; Clomipramine; Drug Compounding; Eosine Yellowish-(YS); Fluorescent Dyes; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Osmolar Concentration; Spectrometry, Fluorescence; Temperature | 2013 |
Chronic pain treatment: the influence of tricyclic antidepressants on serotonin release and uptake in mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Cells, Cultured; Chronic Pain; Clomipramine; Imipramine; Mast Cells; Rats; Rats, Wistar; Serotonin | 2013 |
Glucosylceramide and lysophosphatidylcholines as potential blood biomarkers for drug-induced hepatic phospholipidosis.
Topics: Amitriptyline; Animals; Bile Ducts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Clomipramine; Discriminant Analysis; Disease Models, Animal; Glucosylceramides; Hepatocytes; Imipramine; Least-Squares Analysis; Liver; Lysophosphatidylcholines; Lysosomal Storage Diseases; Male; Mass Spectrometry; Metabolomics; Multivariate Analysis; Predictive Value of Tests; Rats | 2014 |
A simple dried blood spot method for therapeutic drug monitoring of the tricyclic antidepressants amitriptyline, nortriptyline, imipramine, clomipramine, and their active metabolites using LC-MS/MS.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Calibration; Chromatography, Liquid; Clomipramine; Depressive Disorder, Major; Dried Blood Spot Testing; Drug Monitoring; Hematocrit; Humans; Imipramine; Limit of Detection; Nortriptyline; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
A case study in treating chronic comorbid obsessive-compulsive disorder and depression with behavioral activation and pharmacotherapy.
Topics: Amitriptyline; Antidepressive Agents; Behavior Therapy; Chronic Disease; Clomipramine; Depressive Disorder, Major; Duloxetine Hydrochloride; Humans; Lithium Compounds; Male; Middle Aged; Obsessive-Compulsive Disorder; Treatment Outcome | 2015 |
Drug-induced Creutzfeldt-Jakob disease-like syndrome: early CSF analysis as useful tool for differential diagnosis.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cognitive Dysfunction; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male | 2018 |
Effect of CYP2C19 polymorphisms on antidepressant prescription patterns and treatment emergent mania in bipolar disorder.
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Clomipramine; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Depressive Disorder, Major; Humans; Mania; Polymorphism, Single Nucleotide; Sertraline | 2023 |