amitriptyline has been researched along with chlorpheniramine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (43.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (28.13) | 29.6817 |
| 2010's | 9 (28.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Chiang, GH; Unger, SH | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Keserü, GM | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Casas Carnicero, J; Fernández de la Gandara, F; Velasco Martin, A | 1 |
| Ferrari, C; Marmiroli, N; Puglisi, PP; Sabatini, MA; Tedeschi, F; Truzzi, G | 1 |
| Rumack, BH | 1 |
| Greengard, P; Quinn, GP; Reid, MB | 1 |
| Lish, PM; Peters, EL; Robbins, SI | 1 |
| Brittain, RT | 1 |
| Baum, T; Gluckman, MI | 1 |
| Colson, SH; Tolson, WW; Umberger, EJ | 1 |
| Fuxe, K; Jonsson, G; Lidbrink, P | 1 |
| Schrold, J | 1 |
| Lassen, JB | 1 |
2 review(s) available for amitriptyline and chlorpheniramine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
30 other study(ies) available for amitriptyline and chlorpheniramine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.
Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface | 2014 |
Effects of antidepressants on alcohol-induced gastric mucosal injury in rats.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpheniramine; Cimetidine; Ethanol; Female; Gastric Mucosa; Maprotiline; Mianserin; Rats; Rats, Inbred Strains; Stomach Ulcer; Trimipramine | 1989 |
Relationship between growth inhibition and mitochondrial function in petite-negative yeasts. II. Effects of central nervous system drugs upon pathogenic and non-pathogenic Candida species.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Candida; Cell Division; Chlorpheniramine; Chlorpromazine; Clomipramine; Cytochromes; Electrophoresis, Polyacrylamide Gel; Imipramine; Mitochondria; Oxygen Consumption; Promazine | 1985 |
Anticholinergic poisoning: treatment with physostigmine.
Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Chlorpheniramine; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Male; Parasympatholytics; Phenylpropanolamine; Physostigmine; Plants; Poisoning | 1973 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
Specificity of antihistamine drugs and involvement of the adrenergic system in histamine deaths in the guinea pig.
Topics: Adrenal Medulla; Aerosols; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Diphenhydramine; Drug Antagonism; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imipramine; Phenothiazines; Shock, Septic; Sympatholytics; Tripelennamine | 1966 |
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl | 1966 |
The pharmacology of iprindole, a new antidepressant.
Topics: Acetylcholine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Appetite; Atropine; Blepharoptosis; Blood Pressure; Body Temperature; Body Weight; Brain; Chlorpheniramine; Dogs; Drug Synergism; Electric Stimulation; Guanethidine; Guinea Pigs; Histamine H1 Antagonists; Ileum; Imipramine; In Vitro Techniques; Indoles; Liver; Male; Methamphetamine; Mice; Myocardium; Norepinephrine; Rats; Reserpine; Tritium; Vas Deferens | 1969 |
The effects of some centrally acting drugs on the glucocorticoid induction of hepatic tyrosine transaminase.
Topics: Adrenalectomy; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Desipramine; Diphenhydramine; Enzyme Induction; Female; Fluocinolone Acetonide; Fluorometholone; Glucocorticoids; Hydrocortisone; Imipramine; Liver; Male; Prednisone; Proadifen; Promazine; Promethazine; Rats; Reserpine; Sex Factors; Triflupromazine; Tyrosine Transaminase | 1969 |
The effect of imipramine-like drugs and antihistamine drugs on uptake mechanisms in the central noradrenaline and 5-hydroxytryptamine neurons.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Brompheniramine; Chlorpheniramine; Desipramine; Dibenzazepines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Imipramine; Male; Microscopy, Fluorescence; Monoamine Oxidase Inhibitors; Neurons; Nialamide; Norepinephrine; Rats; Reflex; Reserpine; Serotonin | 1971 |
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine | 1972 |
The effect of p-chloroamphetamine on motility in rats after inhibition of monoamine synthesis, storage, uptake and receptor interaction.
Topics: Amitriptyline; Amphetamine; Animals; Biogenic Amines; Catecholamines; Chlorine; Chlorpheniramine; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Female; Haloperidol; Imipramine; Methyltyrosines; Motor Activity; Rats; Receptors, Cholinergic; Serotonin Antagonists; Spiro Compounds; Time Factors | 1974 |