amitriptyline and chloroquine

amitriptyline has been researched along with chloroquine in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (32.14)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (25.00)	29.6817
2010's	11 (39.29)	24.3611
2020's	1 (3.57)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Drenckhahn, D; Lüllmann-Rauch, R	1
Frisch, W; Lüllmann-Rauch, R	1
Mason, CG	1
Hanno, PM; Wein, AJ	1
Lüllmann, H; Lüllmann-Rauch, R; Wassermann, O	1
Bwibo, NO	1
Banez, RJ; Combs, HF; Decker, WJ; Treuting, JJ	1
Clèdes, J; Favarel-Garrigues, JC; Potaux, L; Sagardiluz, J	1
Bennett, JC; Dodson, WH; McBride, WW	1
Carcasona, C; Eichhorn, P; Gavaldà, A; Godessart, N; Pérez, B; Tarrasón, G	1
Park, SY; Zinnah, KMA	1

Reviews

4 review(s) available for amitriptyline and chloroquine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Ocular accumulation and toxicity of certain systemically administered drugs. Journal of toxicology and environmental health, 1977, Volume: 2, Issue:5 Topics: Amitriptyline; Animals; Chloroquine; Cornea; Eye; Eye Diseases; Female; Haplorhini; Humans; Lens, Crystalline; Phenothiazines; Pregnancy; Retinal Diseases; Rifampin; Structure-Activity Relationship; Thioxanthenes; Time Factors	1977
Medical treatment of interstitial cystitis (other than Rimso-50/Elmiron). Urology, 1987, Volume: 29, Issue:4 Suppl Topics: Administration, Intravesical; Administration, Oral; Amitriptyline; Azathioprine; Benzenesulfonates; Benzydamine; Chloroquine; Cystitis; Heparin; Histamine H1 Antagonists; Humans; Hydroxychloroquine; Pentosan Sulfuric Polyester; Prednisolone; Silver Nitrate	1987
[Drug-induced phospholipid storage disease]. Deutsche medizinische Wochenschrift (1946), 1973, Aug-31, Volume: 98, Issue:35 Topics: Adrenal Gland Diseases; Amitriptyline; Animals; Anticholesteremic Agents; Appetite Depressants; Body Weight; Cardiomyopathies; Chemical Phenomena; Chemistry; Chloroquine; Chlorphentermine; Drug Interactions; Female; Fenfluramine; Humans; Iprindole; Lipidoses; Lung Diseases; Lysosomes; Male; Phospholipids; Piperazines; Rats; Testicular Diseases; Thyroid Diseases; Triparanol	1973

Other Studies

24 other study(ies) available for amitriptyline and chloroquine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs. Neuroscience, 1979, Volume: 4, Issue:4 Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Chlorpromazine; Female; Imipramine; Iprindole; Male; Microscopy, Electron; Muscles; Muscular Diseases; Phentermine; Piperazines; Psychotropic Drugs; Quinacrine; Rats; Triparanol	1979
Differential effects of chloroquine and of several other amphiphilic cationic drugs upon rat choroid plexus. Acta neuropathologica, 1979, May-15, Volume: 46, Issue:3 Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Choroid Plexus; Clomipramine; Female; Hexestrol; Inclusion Bodies; Iprindole; Male; Microscopy, Electron; Quinacrine; Rats	1979
Accidental poisoning in children in Uganda. British medical journal, 1969, Dec-06, Volume: 4, Issue:5683 Topics: Amitriptyline; Aspirin; Barbiturates; Child; Child, Preschool; Chloroquine; Codeine; Dapsone; Diazepam; Ethanol; Female; Humans; Infant; Iron; Kerosene; Male; Pesticides; Poisoning; Quinine; Tetrachloroethylene; Uganda	1969
Dialysis of drugs against activated charcoal. Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3 Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors	1971
[Cardiac complications in acute poisoning]. Journal de medecine de Bordeaux et du Sud-Ouest, 1967, Volume: 144, Issue:7 Topics: Adolescent; Adult; Amitriptyline; Arrhythmias, Cardiac; Child; Child, Preschool; Chloroquine; Digitalis Glycosides; Electrocardiography; Heart; Humans; Imipramine; Middle Aged; Poisoning; Quinine	1967
Management of rheumatoid arthritis. Southern medical journal, 1969, Volume: 62, Issue:3 Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health Personnel; Barbiturates; Chlordiazepoxide; Chloroquine; Exercise Therapy; Gold; Hospitalization; Hot Temperature; Humans; Indomethacin; Injections, Intra-Articular; Lidocaine; Mechlorethamine; Phenylbutazone; Physical Therapy Modalities; Physician-Patient Relations; Prednisolone; Rest	1969
Characterization of the chloroquine-induced mouse model of pruritus using an automated behavioural system. Experimental dermatology, 2017, Volume: 26, Issue:11 Topics: Administration, Oral; Amitriptyline; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Antipruritics; Aprepitant; Behavior, Animal; Chloroquine; Cyproheptadine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Morphinans; Morpholines; Motor Activity; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pattern Recognition, Automated; Pruritus; Signal Processing, Computer-Assisted; Skin; Spiro Compounds; Vibration; Video Recording	2017
Sensitizing TRAIL‑resistant A549 lung cancer cells and enhancing TRAIL‑induced apoptosis with the antidepressant amitriptyline. Oncology reports, 2021, Volume: 46, Issue:1 Topics: A549 Cells; Amitriptyline; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Microtubule-Associated Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA-Binding Proteins; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation	2021