amitriptyline and buspirone

amitriptyline has been researched along with buspirone in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's5 (21.74)18.2507
2000's5 (21.74)29.6817
2010's11 (47.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Amlaiky, N; Hen, R; Plassat, JL1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Giordano, J; Rogers, LW1
Gammans, RE; LaBudde, JA; Mayol, RF1
Gatzonis, S; Ilias, A; Mitsikostas, DD; Thomas, A1
Overall, KL1
Dodman, NH; Moon-Fanelli, AA; Sawyer, LS1
Maaswinkel, H; Weng, W; Zhu, L1
Astegiano, M; Caviglia, GP; Cisarò, F; Fagoonee, S; Pellicano, R; Ribaldone, DG; Rosso, C; Saracco, GM; Sguazzini, C; Smedile, A1
Banchs, JE; Copeland, LA; McNeal, CJ; Stock, EM; Zeber, JE1

Reviews

2 review(s) available for amitriptyline and buspirone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Metabolism and disposition of buspirone.
    The American journal of medicine, 1986, Mar-31, Volume: 80, Issue:3B

    Topics: Absorption; Administration, Oral; Adolescent; Adult; Aged; Aging; Amitriptyline; Animals; Anxiety Disorders; Biological Availability; Blood Proteins; Buspirone; Carbon Radioisotopes; Female; Food; Half-Life; Humans; Injections, Intravenous; Kidney Diseases; Kinetics; Liver Cirrhosis; Male; Pyrimidines; Sex Factors

1986

Trials

1 trial(s) available for amitriptyline and buspirone

ArticleYear
Buspirone vs amitriptyline in the treatment of chronic tension-type headache.
    Acta neurologica Scandinavica, 1997, Volume: 96, Issue:4

    Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Buspirone; Depression; Female; Headache; Humans; Male; Middle Aged; Personality Inventory; Somatoform Disorders; Treatment Outcome

1997

Other Studies

20 other study(ies) available for amitriptyline and buspirone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of systemically administered monoamine reuptake blocking agents on patterns of buspirone-induced analgesia in rats.
    Life sciences, 1990, Volume: 47, Issue:11

    Topics: Amitriptyline; Analgesia; Animals; Brain Chemistry; Buspirone; Desipramine; Dopamine; Drug Interactions; Female; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Serotonin; Spinal Cord

1990
Animal behavior case of the month. A dog was examined because of profound separation anxiety.
    Journal of the American Veterinary Medical Association, 1998, Jun-01, Volume: 212, Issue:11

    Topics: Acepromazine; Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Anxiety, Separation; Behavior Therapy; Buspirone; Contraindications; Dog Diseases; Dogs; Drug Therapy, Combination; Follow-Up Studies; Male; Thyroxine

1998
Psychogenic alopecia in cats: 11 cases (1993-1996).
    Journal of the American Veterinary Medical Association, 1999, Jan-01, Volume: 214, Issue:1

    Topics: Alopecia; Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Breeding; Buspirone; Cat Diseases; Cats; Clomipramine; Data Collection; Female; Grooming; Male; Retrospective Studies; Stress, Physiological

1999
The immediate and the delayed effects of buspirone on zebrafish (Danio rerio) in an open field test: a 3-D approach.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Analysis of Variance; Animals; Anti-Anxiety Agents; Buspirone; Clomipramine; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Imaging, Three-Dimensional; Movement; Selective Serotonin Reuptake Inhibitors; Time Factors; Zebrafish

2012
Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by 13C-octanoic Acid Breath Test.
    Minerva medica, 2017, Volume: 108, Issue:6

    Topics: Adult; Amitriptyline; Benzamides; Breath Tests; Buspirone; Caprylates; Domperidone; Drug Evaluation; Drug Resistance; Dyspepsia; Female; Gastric Emptying; Humans; Male; Middle Aged; Postprandial Period; Proton Pump Inhibitors; Retrospective Studies; Satiation

2017
Psychotropic Pharmacotherapy Associated With QT Prolongation Among Veterans With Posttraumatic Stress Disorder.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Arrhythmias, Cardiac; Buspirone; Female; Humans; Male; Methadone; Middle Aged; Piperazines; Psychotropic Drugs; Quetiapine Fumarate; Sotalol; Stress Disorders, Post-Traumatic; Thiazoles; Veterans; Young Adult

2018