amitriptyline has been researched along with bupivacaine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (66.67) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Maneksha, FR; Mirza, H; Poppers, PJ | 1 |
| Gerner, P; Mujtaba, M; Sinnott, CJ; Wang, GK | 1 |
| Gerner, P; Khan, MA; Kuo Wang, G | 1 |
| Ecoffey, C; Estèbe, JP; Gentili, ME; Le Corre, P; Leduc, C; Moulinoux, JP | 2 |
| Abdi, S; Gerner, P; Haderer, A; Jarolim, P; Srinivasa, V; Wang, GK | 1 |
| Gulec, A; Karadasli, H; Karakurum, G; Oner, U; Pirbudak, L; Satana, T | 1 |
| Eappen, S; Fridrich, P; Gerner, P; Jaeger, W; Schernhammer, E; Wang, GK; Zizza, AM | 1 |
| Barnet, CS; Kohane, DS; Tse, JY | 1 |
| Kang, X; Liu, H; Song, L; Wen, C; Xiao, H; Yang, B; Yang, F | 1 |
| Chauhan, A; Howell, BA | 1 |
| Bae, SA; Kohane, DS; Langer, R; Lawlor, MW; Shichor, I; Shomron, N; Zoldan, J | 1 |
| Christian, MR; Mycyk, MB; Pallasch, EM; Wahl, M | 1 |
1 trial(s) available for amitriptyline and bupivacaine
| Article | Year |
|---|---|
Phase Ia and Ib study of amitriptyline for ulnar nerve block in humans: side effects and efficacy.
Topics: Adult; Amitriptyline; Bupivacaine; Double-Blind Method; Erythema; Female; Humans; Male; Middle Aged; Nerve Block; Pain; Ulnar Nerve | 2004 |
20 other study(ies) available for amitriptyline and bupivacaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Complex regional pain syndrome (CRPS) with resistance to local anesthetic block: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Lidocaine; Nerve Block; Physical Therapy Modalities; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympathetic Nervous System | 2000 |
Amitriptyline versus bupivacaine in rat sciatic nerve blockade.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sodium Channel Blockers; Time Factors | 2001 |
Amitriptyline for prolonged cutaneous analgesia in the rat.
Topics: Amitriptyline; Anesthetics, Local; Animals; Area Under Curve; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Male; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
The effect of local anesthetics and amitriptyline on peroxidation in vivo in an inflammatory rat model: preliminary reports.
Topics: Amides; Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Bupivacaine; Carrageenan; Inflammation; Lidocaine; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Ropivacaine; Thiobarbituric Acid Reactive Substances | 2002 |
The relative toxicity of amitriptyline, bupivacaine, and levobupivacaine administered as rapid infusions in rats.
Topics: Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Bupivacaine; Electrocardiography; Heart Arrest; Heart Rate; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tachycardia, Ventricular; Ventricular Fibrillation | 2003 |
Sympathetic blockade and amitriptyline in the treatment of reflex sympathetic dystrophy.
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Reflex Sympathetic Dystrophy; Sympatholytics; Treatment Outcome | 2003 |
Site 1 sodium channel blockers prolong the duration of sciatic nerve blockade from tricyclic antidepressants.
Topics: Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Injections, Subcutaneous; Male; Motor Activity; Nerve Block; Pain Measurement; Rats; Rats, Sprague-Dawley; Saxitoxin; Sciatic Nerve; Sodium Channel Blockers; Statistics, Nonparametric; Tetrodotoxin; Time Factors | 2004 |
Contralateral effect of amitriptyline and bupivacaine for sciatic nerve block in an animal model of inflammation.
Topics: Amitriptyline; Anesthetics, Local; Animals; Bupivacaine; Carrageenan; Disease Models, Animal; Hyperalgesia; Male; Microspheres; Nerve Block; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2004 |
[Peripheral anti-hyperalgesic effect and neurotoxicologic screening of amitriptyline and bupivacaine on sciatic nerve blockade chronically on neuropathic pain in rats].
Topics: Amitriptyline; Animals; Bupivacaine; Male; Nerve Block; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy | 2009 |
A physiologically based pharmacokinetic (PBPK) model for predicting the efficacy of drug overdose treatment with liposomes in man.
Topics: Algorithms; Amitriptyline; Anesthetics, Local; Antidepressive Agents, Tricyclic; Area Under Curve; Bupivacaine; Computer Simulation; Drug Carriers; Drug Overdose; Humans; Imipramine; Liposomes; Models, Biological; Models, Statistical; Pharmacokinetics; Phosphatidylethanolamines; Phosphatidylglycerols; Predictive Value of Tests; Software; Solubility; Tissue Distribution | 2010 |
Toxicogenomic analysis of a sustained release local anesthetic delivery system.
Topics: Amitriptyline; Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Dexamethasone; Gene Expression Regulation; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Sciatic Nerve; Tetrodotoxin; Toxicogenetics | 2012 |
Lipid rescue 911: Are poison centers recommending intravenous fat emulsion therapy for severe poisoning?
Topics: Acute Disease; Adult; Amitriptyline; Bupivacaine; Drug Overdose; Fat Emulsions, Intravenous; Guideline Adherence; Health Care Surveys; Humans; Physician Executives; Poison Control Centers; Poisoning; Practice Guidelines as Topic; Remote Consultation; Severity of Illness Index; Shock; Societies, Medical; United States; Verapamil; Xenobiotics | 2013 |