amitriptyline and baclofen

amitriptyline has been researched along with baclofen in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.00)18.7374
1990's7 (23.33)18.2507
2000's6 (20.00)29.6817
2010's13 (43.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goldblatt, D1
Kikuchi, A; Kim, YS; Takai, Y1
Maj, M; Monteleone, P; Steardo, L; Tanzillo, C1
Iovino, M; Maj, M; Monteleone, P; Steardo, L1
Goodwin, GM; Gray, JA; Green, AR; Heal, DJ1
Goodwin, WB; Guyenet, PG; Huangfu, D1
Borodkin, IuS; Burakov, AM; Grinenko, AIa; Ivanov, VB; Karandashova, GF; Krupitskiĭ, EM; Lapin, IP1
Burakov, AM; Ivanov, VB; Krandashova, GF; Krupitsky, EM; Lapin, IP1
Borodkin, IuS; Burakov, AM; Grinenko, AIa; Krupitskiĭ, EM1
De Vry, J; Jentzsch, KR1
He, L; Wu, B; Zhou, M1
Anand, JS; Habrat, B; Korolkiewicz, R; Sut, M1
Barton, DL; Bearden, JD; Christensen, B; Green, NB; Hoff, KL; Kugler, JW; Lanier, KS; Loprinzi, CL; Mattar, BI; Qin, R; Reddy, PS; Riepl, M; Rowland, KM; Wos, EJ1
Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhou, M1
Abdala, N; Abdalla, C; Abrahão, A; Barsottini, OG; Braga-Neto, P; Pedroso, JL; Rivero, RL1
Cohen, SM; Misono, S1
Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M1
Benoliel, R; Haviv, Y; Sharav, Y; Zadik, Y1
Bak, K; Bleeker, J; Cavaletti, G; Chauhan, C; Dworkin, RH; Gavin, P; Hershman, DL; Lacchetti, C; Lavino, A; Lavoie Smith, EM; Loprinzi, CL; Lustberg, MB; Paice, J; Schneider, B; Smith, ML; Smith, T; Terstriep, S; Wagner-Johnston, N1
Donato, AA; Hao, D; Olugbodi, A; Udechukwu, N1
Dorsey, SG; Griffioen, MA; O'Toole, RV; Renn, CL; Ziegler, ML1
Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF; Vine, SM1

Reviews

6 review(s) available for amitriptyline and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Non-antiepileptic drugs for trigeminal neuralgia.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia

2006
Non-antiepileptic drugs for trigeminal neuralgia.
    The Cochrane database of systematic reviews, 2011, Jan-19, Issue:1

    Topics: Amitriptyline; Analgesics; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia

2011
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013, Volume: 148, Issue:3

    Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Pregabalin; Quality of Life

2013
Non-antiepileptic drugs for trigeminal neuralgia.
    The Cochrane database of systematic reviews, 2013, Dec-03, Issue:12

    Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia

2013
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jun-20, Volume: 32, Issue:18

    Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States

2014

Trials

4 trial(s) available for amitriptyline and baclofen

ArticleYear
[The use of baclofen for treating affective disorders in alcoholism].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:1

    Topics: Adult; Alcoholism; Amitriptyline; Baclofen; Diazepam; Drug Evaluation; Humans; Ligands; Mood Disorders; Psychological Tests; Receptors, GABA-B

1994
Baclofen administration for the treatment of affective disorders in alcoholic patients.
    Drug and alcohol dependence, 1993, Volume: 33, Issue:2

    Topics: Administration, Oral; Adult; Alcoholism; Amitriptyline; Anxiety Disorders; Baclofen; Blood Platelets; Depressive Disorder; Diazepam; Dopamine; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Humans; Male; Monoamine Oxidase; Personality Inventory; Receptors, GABA-A; Receptors, GABA-B; Serotonin

1993
[Effect of pharmacotherapy of affective disorders on the psycho-semantics of alcoholic patients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1995, Volume: 95, Issue:6

    Topics: Alcoholism; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Color Perception Tests; Consciousness; Diazepam; GABA Agonists; Humans; MMPI; Mood Disorders; Semantic Differential; Semantics

1995
A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:6

    Topics: Administration, Cutaneous; Adrenergic Uptake Inhibitors; Aged; Amitriptyline; Antineoplastic Agents; Baclofen; Double-Blind Method; Drug Combinations; Excitatory Amino Acid Antagonists; Female; GABA-B Receptor Agonists; Gels; Humans; Ketamine; Lecithins; Male; Middle Aged; Peripheral Nervous System Diseases; Poloxamer; Treatment Outcome

2011

Other Studies

20 other study(ies) available for amitriptyline and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Treatment of amyotrophic lateral sclerosis.
    Advances in neurology, 1977, Volume: 17

    Topics: Aging; Amitriptyline; Amyotrophic Lateral Sclerosis; Baclofen; Braces; Dantrolene; Deglutition Disorders; Environmental Exposure; Exercise Therapy; Guanidines; Humans; Male; Middle Aged; Physician-Patient Relations; Spasm; Speech Disorders; Syndrome; Virus Diseases

1977
Effect of chlorpromazine on the smg GDS action.
    Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3

    Topics: Amitriptyline; Baclofen; Blood Platelets; Cell Membrane; Chlorpromazine; Dibucaine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; Phenobarbital; Phosphatidic Acids; Phospholipids; Propranolol; rap GTP-Binding Proteins

1992
Chronic antidepressant drug treatment does not affect GH response to baclofen in depressed subjects.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:2

    Topics: Adult; Amitriptyline; Baclofen; Depressive Disorder; Drug Interactions; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hypothalamus; Male; Middle Aged; Receptors, GABA-A; Secretory Rate; Stimulation, Chemical; Up-Regulation

1990
GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach.
    Journal of affective disorders, 1990, Volume: 20, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents; Baclofen; Brain; Depressive Disorder; Fluoxetine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Imipramine; Male; Middle Aged; Personality Tests; Receptors, GABA-A

1990
Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: 5,7-Dihydroxytryptamine; Amitriptyline; Animals; Antidepressive Agents; Baclofen; Body Temperature; Electroshock; Flurazepam; Hypnotics and Sedatives; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Neural Pathways; Pentobarbital; Receptors, GABA-A

1987
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors

1995
Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Alkanesulfonates; Amines; Amitriptyline; Animals; Baclofen; Behavior, Animal; Benzoxazines; Carbamazepine; Cyclohexanecarboxylic Acids; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Molecular Structure; Morphine; Morpholines; Naphthalenes; Nitriles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonic Acids

2004
[Misuse of substances theoretically without abuse potential--case series].
    Przeglad lekarski, 2009, Volume: 66, Issue:6

    Topics: Amitriptyline; Analgesics; Anti-Inflammatory Agents; Antidepressive Agents; Baclofen; Benzydamine; Cyclohexanols; Drug Overdose; Female; Humans; Imidazoles; Male; Muscle Relaxants, Central; Nasal Decongestants; Poisoning; Substance Abuse Detection; Thiazepines; Venlafaxine Hydrochloride

2009
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family.
    Arquivos de neuro-psiquiatria, 2011, Volume: 69, Issue:2B

    Topics: Adult; Amitriptyline; Baclofen; Female; Humans; Magnetic Resonance Imaging; Male; Muscle Relaxants, Central; Muscle Spasticity; Pedigree; Spinocerebellar Ataxias

2011
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2014
Trauma-induced adiposis dolorosa (Dercum's disease).
    BMJ case reports, 2018, Mar-28, Volume: 2018

    Topics: Accidents, Traffic; Adipose Tissue; Adiposis Dolorosa; Adult; Amitriptyline; Analgesics, Non-Narcotic; Angiomyolipoma; Baclofen; Chronic Pain; Clonidine; Diagnosis, Differential; Humans; Ibuprofen; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed; Upper Extremity

2018
Change in Pain Score after Administration of Analgesics for Lower Extremity Fracture Pain during Hospitalization.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2019, Volume: 20, Issue:2

    Topics: Adult; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents; Baclofen; Bones of Lower Extremity; Cohort Studies; Duloxetine Hydrochloride; Female; Fractures, Bone; Gabapentin; Hospitalization; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain Management; Pain Measurement; Pregabalin; Retrospective Studies

2019
Comparative Risk of Opioid Overdose With Concomitant Use of Prescription Opioids and Skeletal Muscle Relaxants.
    Neurology, 2022, 09-27, Volume: 99, Issue:13

    Topics: Amitriptyline; Analgesics, Opioid; Baclofen; Benzodiazepines; Carisoprodol; Chlorzoxazone; Cohort Studies; Humans; Hydrocodone; Methocarbamol; Narcotic Antagonists; Neuromuscular Agents; Opiate Overdose; Orphenadrine; Oxycodone; Prescriptions; Sepsis; Substance-Related Disorders

2022