amitriptyline has been researched along with amitriptyline n-oxide in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (56.25) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Becher, B; Breyer-Pfaff, U; Fischer, W; Müller, WE; Scholz, E; Taneri, Z | 1 |
| Dilger, C; Fischer, W; Hutt, V; Jaeger, H; Mosberg, H; Pabst, G; Theodor, R | 1 |
| Heinrich, K; Klieser, E; Lehmann, E; Tegeler, J | 1 |
| Koch, H | 1 |
| Berger, M; Laubenthal, S; Müller, WE; Riemann, D; Velthaus, S | 1 |
| Borbe, HO; Zierenberg, O | 1 |
| Borbe, HO; Dimpfel, W; Spüler, M | 1 |
| Brand, T; Filser, JG; Kaumeier, S; Müller, WE; Schanz, H; Terlinden, R | 1 |
| Borbe, HO; Terlinden, R | 1 |
| Kellhammer, U; Pfaffenrath, V; Pöllmann, W | 1 |
| Baumann, U; Eckmann, F; Stieglitz, RD | 1 |
| Johannes, KJ; Jungkunz, G; Kuss, HJ | 1 |
| Facino, RM; Pirillo, D; Santagostino, G | 1 |
| de Wolff, FA; Edelbroek, PM | 1 |
| Maj, J; Michaluk, J; Rogóz, Z; Skuza, G; Vetulani, J | 1 |
| Beinroth, AS; Harrer, G | 1 |
| Schröder, HG | 1 |
| Danek, L; Melzacka, M | 1 |
| Hertrich, O | 1 |
| Borromei, A | 1 |
| Nadjafi, A | 1 |
| Seefried, S | 1 |
| Jensen, KM | 1 |
| Diener, HC; Fischer, W; Haase, W; Isler, H; Meyer, C; Pfaffenrath, V; Scholz, E; Taneri, Z; Wessely, P; Zaiser-Kaschel, H | 2 |
| Diehl, B; Heinrich, T; König, W | 1 |
| Degen, J; Fischer, W; Höxter, G; Pintar, P; Seiberling, M; Steinhauer, HB; Wölke, E | 1 |
| Feuerstein, TJ; Fischer, W; Kiefer, G | 1 |
| Breyer-Pfaff, U | 1 |
| Li, H; Sumarah, MW; Topp, E | 1 |
| Dick, S; Keene, W; Swales, J; Temesi, D | 1 |
1 review(s) available for amitriptyline and amitriptyline n-oxide
| Article | Year |
|---|---|
The metabolic fate of amitriptyline, nortriptyline and amitriptylinoxide in man.
Topics: Amitriptyline; Humans; Nortriptyline | 2004 |
13 trial(s) available for amitriptyline and amitriptyline n-oxide
| Article | Year |
|---|---|
Urinary metabolites of amitriptylinoxide and amitriptyline in single-dose experiments and during continuous therapy.
Topics: Adult; Amitriptyline; Biotransformation; Chromatography, High Pressure Liquid; Female; Headache; Humans; Male | 1992 |
[Plasma and urine kinetics of amitriptyline oxide and its metabolites. Comparison of intravenous infusion and oral administration in volunteers].
Topics: Administration, Oral; Adult; Amitriptyline; Biotransformation; Blood Pressure; Female; Humans; Infusions, Intravenous; Male; Nortriptyline; Pulse | 1991 |
Double-blind study of the therapeutic efficacy and tolerability of amitriptylinoxide in comparison with amitriptyline.
Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 1990 |
Steady-state plasma levels during antidepressant therapy with amitriptyline and amitriptylinoxide.
Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic | 1990 |
Self-rating data as a selecting factor in clinical trials of psychotropic drugs.
Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychological Tests; Trazodone | 1985 |
Urinary excretion of amitriptyline N-oxide in humans.
Topics: Adult; Amitriptyline; Buffers; Clinical Trials as Topic; Female; Humans; Hydroxylation; Male; Nitrogen Oxides; Nortriptyline; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Amitriptyline: looking through the therapeutic window.
Topics: Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male | 1984 |
[Clinical testing of equilibrin in hospitalized depressive patients].
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Middle Aged; Tablets | 1982 |
A new antidepressant agent: amitriptyline-N-oxide.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales | 1982 |
Efficacy and tolerability of amitriptylinoxide in the treatment of chronic tension-type headache: a multi-centre controlled study.
Topics: Adolescent; Adult; Aged; Amitriptyline; Chronic Disease; Depression; Dose-Response Relationship, Drug; Double-Blind Method; Evaluation Studies as Topic; Female; Headache; Humans; Male; Middle Aged; Stress, Physiological | 1994 |
A double-blind comparison of amitriptylinoxide versus doxepine in the treatment of severe depression.
Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 1994 |
[Effectiveness and tolerance of amitriptyline oxide in chronic tension headache--a multicenter double-blind study versus amitriptyline versus placebo].
Topics: Adolescent; Adult; Aged; Amitriptyline; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Headache; Humans; Male; Middle Aged | 1993 |
[Comparative study of the pharmacokinetics of amitriptyline oxide and trimipramine after single administration in healthy male probands and patients with renal failure].
Topics: Adult; Aged; Amitriptyline; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Nortriptyline; Trimipramine | 1993 |
18 other study(ies) available for amitriptyline and amitriptyline n-oxide
| Article | Year |
|---|---|
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
REM-suppressing effects of amitriptyline and amitriptyline-N-oxide after acute medication in healthy volunteers: results of two uncontrolled pilot trials.
Topics: Adult; Affect; Amitriptyline; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Male; Pilot Projects; Sleep; Sleep, REM | 1990 |
Amitriptylinoxide: receptor-binding profile compared with other antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Binding, Competitive; Brain; Carrier Proteins; Cattle; Imipramine; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin | 1985 |
Monitoring of the effects of antidepressant drugs in the freely moving rat by radioelectroencephalography (tele-stereo-EEG).
Topics: Amitriptyline; Animals; Antidepressive Agents; Arousal; Brain; Dextroamphetamine; Doxepin; Electroencephalography; Haloperidol; Imipramine; Lysergic Acid Diethylamide; Male; Microcomputers; Nomifensine; Rats; Rats, Inbred F344; Signal Processing, Computer-Assisted; Telemetry | 1988 |
Pharmacokinetics of amitriptyline and amitriptylinoxide after intravenous or oral administration in humans.
Topics: Administration, Oral; Adolescent; Adult; Amitriptyline; Female; Half-Life; Humans; Injections, Intravenous; Male | 1988 |
Determination of amitriptylinoxide and its major metabolites amitriptyline and nortriptyline in plasma by high-performance liquid chromatography.
Topics: Amitriptyline; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Kinetics; Nortriptyline | 1986 |
Combination headache: practical experience with a combination of a beta-blocker and an antidepressive.
Topics: Adult; Amitriptyline; Cluster Headache; Drug Therapy, Combination; Female; Headache; Humans; Male; Metoprolol; Middle Aged; Migraine Disorders; Propranolol | 1986 |
Single oral dose pharmacokinetics of amitriptylinoxide and amitriptyline in humans.
Topics: Administration, Oral; Adult; Amitriptyline; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Nortriptyline | 1985 |
Central action of amitriptyline N-oxide.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Brain; Brain Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Tryptamines | 1982 |
[Multicenter therapy study with the amitriptyline oxide Equilibrin 60--a broad-spectrum antidepressive agent].
Topics: Administration, Oral; Adult; Aged; Amitriptyline; Depression; Depressive Disorder; Female; Humans; Male; Middle Aged; Tablets | 1983 |
Pharmacokinetics of amitriptyline N-oxide in rats after single and prolonged oral administration.
Topics: Administration, Oral; Amitriptyline; Animals; Brain; Kinetics; Male; Rats; Rats, Inbred Strains; Time Factors | 1983 |
[Ataractic treatment in psychiatry and general medicine. Overview of drugs. 2].
Topics: Amitriptyline; Benperidol; Chemical Phenomena; Chemistry; Family Practice; Humans; Mental Disorders; Tranquilizing Agents; Trimeprazine | 1983 |
[Ambulatory therapy of depression with equilibrin].
Topics: Adolescent; Adult; Aged; Ambulatory Care; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Male; Middle Aged | 1982 |
[Equilibrin in elderly depressed patients. Results of a therapy study].
Topics: Adult; Aged; Amitriptyline; Depressive Disorder; Female; Humans; Male; Middle Aged | 1982 |
Determination of amitriptyline-N-oxide, amitriptyline and nortriptyline in serum and plasma by high-performance liquid chromatography.
Topics: Amitriptyline; Animals; Chromatography, High Pressure Liquid; Diazepam; Male; Nortriptyline; Rats | 1980 |
Effects of amitriptyline, amitriptylinoxide, doxepine and clozapine on N-methyl-D-aspartate-evoked release of [3H]-acetylcholine in rat caudatoputamen.
Topics: Acetylcholine; Algorithms; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Caudate Nucleus; Chronic Disease; Clozapine; Doxepin; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Pain; Putamen; Rats; Rats, Wistar | 1999 |
Persistence of the tricyclic antidepressant drugs amitriptyline and nortriptyline in agriculture soils.
Topics: Agriculture; Amitriptyline; Antidepressive Agents, Tricyclic; Environmental Monitoring; Models, Chemical; Nortriptyline; Soil; Soil Pollutants | 2013 |
The stability of amitriptyline N-oxide and clozapine N-oxide on treated and untreated dry blood spot cards.
Topics: Amitriptyline; Animals; Chromatography, High Pressure Liquid; Clozapine; Dried Blood Spot Testing; Drug Monitoring; Drug Stability; Rats; Rats, Wistar; Time Factors | 2013 |