amiodarone and warfarin

amiodarone has been researched along with warfarin in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (13.64)	18.7374
1990's	13 (11.82)	18.2507
2000's	35 (31.82)	29.6817
2010's	40 (36.36)	24.3611
2020's	7 (6.36)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C	1
Fouchard, J; Guérin, F; Le, F; Py, A	1
Eddy, AC; Gibaldi, M; Goulart, DA; Heimark, LD; Kunze, K; O'Reilly, RA; Trager, WF; Wienkers, L	1
Lown, B; Podrid, PJ; Raeder, EA	1
Blevins, RD; Faitel, K; Goldman, L; Kerin, NZ; Rubenfire, M	1
Goulart, DA; O'Reilly, RA; Rettie, AE; Trager, WF	1
Bonati, M; Neyroz, P	1
Almog, S; Bank, H; Farfel, Z; Halkin, H; Martinowitz, U; Shafran, N; Weiss, P	1
Buss, DC; Routledge, PA; Stephens, MR; Watt, AH	1
Marcus, FI	1
Byfield, PG; Greenwood, RM; Himsworth, RL; Lalloz, MR	1
Alpert, JS; Asdourian, GK; Haffajee, CI; Love, JC; Sloan, KC	1
Hamer, A; Mandel, WJ; Peter, T; Weiss, D	1
Dalal, JJ; Henderson, AH; Lewis, MJ; Rees, A; Reid, PG	1
Green, GJ; Serlin, MJ; Sibeon, RG	1
D'Arcy, PF	1
Hamer, A; Mandel, WJ; Peter, T; Scheinman, MM; Weiss, D	1
Bank, H; Goldfarb, D; Many, A; Martinowitz, U; Rabinovich, J	1
Gornbein, JA; Middlekauff, HR; Stevenson, WG	1
Birkmeyer, JD; Disch, DL; Greenberg, ML; Holzberger, PT; Malenka, DJ	1
Cheung, B; Kumana, CR; Lam, FM	1
Chan, JC; Chan, TY; Critchley, JA; Tomlinson, B; Young, RP	1
Jolobe, OM	2
Disch, DL; Greenberg, ML; Malenka, DJ	1
Alessandrini, RS; Goldberger, JJ; Kadish, AH; Kane, BJ; McPherson, DD	1
Warner, I; Woeber, KA	1
Kausar, SA	1
Brügemann, J; Crijns, HJ; De Kam, PJ; Tuinenburg, AE; Van Den Berg, MP; Van Gelder, IC	1
Furmaga, EM; Good, CB	1
Bharat, V; Mohanty, B	1
Bauman, JL; Sanoski, CA	1
Fujii, E; Kasanuki, H; Naganuma, M; Nishikata, K; Shiga, T; Tsuchiya, T	1
Khairy, P; Nattel, S	1
Ahn, H; Kim, K; Lee, B; Lee, J; Lee, M; Shin, W; Suh, O	1
Cook, JR; Epstein, AE; Greene, HL; Hallstrom, AP; Hsia, H; Kutalek, SP; Sharma, A; Wilkoff, BL	1
Hirmerová, J; Mádr, T; Suchý, D	1
Andreux, JP; Debray, M; Esquirol, C; Gouin, I; Pautas, E; Siguret, V	1
Jonkaitiene, R; Mizariene, V	1
Corley, SD; DiMarco, JP; Domanski, MJ; Epstein, AE; Geller, N; Greene, HL; Josephson, RA; Kellen, JC; Klein, RC; Krahn, AD; Mickel, M; Mitchell, LB; Nelson, JD; Rosenberg, Y; Schron, E; Shemanski, L; Waldo, AL; Wyse, DG	1
Ezra, D; Farfel, Z; Halkin, H; Kurnik, D; Loebstein, R; Olchovsky, D	1
Canivet, JL; Radermecker, MA; Roediger, L; Yans, T	1
Demircioglu, F; Ersel-Tüzüner, F; Kabukcu, M; Minareci, K; Yanik, E	1
Ekman, S; Fransson-Steen, R; Hagbjörk, AL; Löfgren, S; Terelius, Y	1
Hersi, A; Wyse, DG	1
Corley, SD; DiMarco, JP; Flaker, G; Greene, HL; Mitrani, G; Nemeth, M; Rosenfeld, LE; Safford, RE; Waldo, AL	1
Faiçal, F; Oliveira-Filho, J; Reis, FJ; Torreão, JA; Viana, LC; Vieira-de-Melo, RM; Villar, FA	1
Breskvar, K; Dolzan, V; Grabnar, I; Herman, D; Lainscak, M; Locatelli, I; Mrhar, A; Peternel, P; Stegnar, M	1
Bedard, P; Hendry, P; Kulik, A; Lam, BK; Masters, R; Mesana, TG; Rubens, FD; Ruel, M	1
Kurnik, D; Loebstein, R; Olchovsky, D	1
Biersack, HJ; Brockmann, H; Bucerius, J; Ezziddin, S; Palmedo, H	1
Kishida, H; Tsukada, YT	1
Asinger, RW; Lu, Y; Nelson, BJ; Qi, D; Rausch, DJ; Won, KA	1
Balasubramaniam, R; Kistler, PM	1
Dias-Neto, E; Ojopi, EB; Perini, JA; Rangel, F; Santana, IS; Silva-Assunção, E; Struchiner, CJ; Suarez-Kurtz, G	1
Becker, C; Bowersox, S; Choppin, A; Dennis, DM; Druzgala, P; Irwin, I; Lach, L; McDonald, MG; Paliard, X; Palme, MP; Rettie, AE; Shao, L	1
Edwin, SB; Jennings, DL; Kalus, JS	1
Becker, RC; Fiuzat, M; Shirolkar, SC	1
Reiffel, JA	1
Haber, SL; Pogge, EK	1
Au, NT; McDonald, MG; Rettie, AE; Wittkowsky, AK	1
Lindsay, BD	1
Ahmad, Y; Lip, GY	1
Bajolle, F; Bonnet, D; Loriot, MA; Moreau, C; Siguret, V	1
Cinconze, E; Joppi, R; Mezzalira, L; Pase, D; Pengo, V; Poggiani, C; Rossi, E	1
Gomes, T; Holbrook, AM; Juurlink, DN; Kearon, C; Lam, J; Mamdani, MM; Paterson, M; Pullenayegum, EM; Spencer, FA; Zheng, H	1
Agarwal, V; Lafferty, J; Otterbeck, PE; Parikh, V	1
Cesar, LA; Ferreira, JF; Grinberg, M; Krieger, JE; Pereira, AC; Santos, PC; Scanavacca, M; Soares, RA; Strunz, CM	1
Guo, X; Li, L; Tang, B; Xu, G; Zhang, Y; Zhou, X	1
Al-Khatib, SM; Amerena, J; Avezum, A; Dorian, P; Flaker, G; Garcia, D; Granger, CB; Hanna, M; Harjola, VP; Hohnloser, SH; Hylek, E; Keltai, M; Lopes, RD; Sullivan, RM; Thomas, L; Wallentin, L; Wojdyla, DM	1
Antman, EM; Atar, D; Braunwald, E; Camm, AJ; Giugliano, RP; Heidbuchel, H; Murphy, SA; Ruff, CT; Steffel, J	1
Chen, CH; Chen, CY; Chen, W; Chen, WC; Cheng, WC; Hsia, TC; Li, CH; Liao, WC; Lin, KH; Muo, CH; Wu, BR	1
Conen, D	1
Ege, EJ; Flaker, G; Koerber, SM; Petroski, GF; Riggs, KW; White, RD	1
Pieper, PG	1
Berckmans, P; Covaci, A; Hollanders, K; Maho, W; Peers, B; Remy, S; Verstraelen, S; Witters, H	1
Camargo, HP; Girotto, E; Guidoni, CM; Obreli-Neto, PR; Pereira, LR	1
Block, BL; Nouri, SN	1
Andersson, ML; Holm, J; Lindh, JD; Mannheimer, B	1
Basu, A; Carlson, JJ; Dhanda, DS; Guzauskas, GF; Veenstra, DL	1
de Abajo, FJ; Gaist, D; Martín-Pérez, M; Rodríguez, LAG	1
Avendano, R; Di Biase, L; Diaz, JC; Garcia, MJ; Golive, A; Krumerman, AK; Lupercio, F; Natale, A; Quispe, R; Romero, J	1
Cohen, JL; Kozikowski, A; Pekmezaris, R; Qiu, G; Sinvani, L; Spyropoulos, AC; Thompson, E; Wang, JJ	1
Brown, JR; Hennessy, S; Miano, TA; Shashaty, MGS; Yang, W; Zuppa, A	1
Auvity, S; Cisternino, S; Nguyen, D; Postaire, M; Schlatter, J; Secretan, PH; Vidal, F	1
Desai, NR; Fonarow, GC; Lewis, WR; Matsouaka, R; Piccini, JP; Sciria, CT; Turakhia, MP; Zhao, X	1
Chen, W; Fu, J; Jiang, S; Lv, M; Wu, T; Xia, X; Zhang, J	1
De Backer, TL; Grymonprez, M; Lahousse, L; Steurbaut, S; Vanspranghe, K	1
Bando, Y; Ishii, H; Otori, K; Yokota, N	1
Beaulieu-Jones, BR; Haime, M; Lin, B; Phillips, AM; Quin, JA	1

Reviews

17 review(s) available for amiodarone and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Isolated atrial fibrillation. The risk of embolism and its prevention]. Presse medicale (Paris, France : 1983), 1992, Jun-27, Volume: 21, Issue:24 Topics: 4-Hydroxycoumarins; Adult; Aged; Aged, 80 and over; Amiodarone; Anticoagulants; Aspirin; Atrial Fibrillation; Female; Humans; Indenes; Intracranial Embolism and Thrombosis; Male; Middle Aged; Recurrence; Risk Factors; Vitamin K; Warfarin	1992
Antiarrhythmic prophylaxis vs warfarin anticoagulation to prevent thromboembolic events among patients with atrial fibrillation. A decision analysis. Archives of internal medicine, 1995, May-08, Volume: 155, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Atrial Fibrillation; Confounding Factors, Epidemiologic; Decision Support Techniques; Electric Countershock; Female; Humans; Male; Middle Aged; Quinidine; Risk; Thromboembolism; Treatment Outcome; Warfarin	1995
Managing chronic atrial fibrillation: a Markov decision analysis comparing warfarin, quinidine, and low-dose amiodarone. Annals of internal medicine, 1994, Mar-15, Volume: 120, Issue:6 Topics: Aged; Amiodarone; Atrial Fibrillation; Chronic Disease; Decision Support Techniques; Humans; Markov Chains; Quality of Life; Quinidine; Risk Factors; Warfarin	1994
Therapeutic strategies for atrial fibrillation. The value of decision analysis. Cardiology clinics, 1996, Volume: 14, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; Chronic Disease; Decision Support Techniques; Electric Countershock; Humans; Markov Chains; Quinidine; Randomized Controlled Trials as Topic; Warfarin	1996
New insights into the mechanisms and management of atrial fibrillation. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Oct-29, Volume: 167, Issue:9 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiac Catheterization; Humans; Practice Guidelines as Topic; Propafenone; Sotalol; Warfarin	2002
Complex drug-drug-disease interactions between amiodarone, warfarin, and the thyroid gland. Medicine, 2004, Volume: 83, Issue:2 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Drug Interactions; Female; Humans; Male; Middle Aged; Risk Factors; Thyroid Gland; Thyrotoxicosis; Warfarin	2004
Management of atrial fibrillation. Current problems in cardiology, 2005, Volume: 30, Issue:4 Topics: Adrenergic beta-Antagonists; Algorithms; Amiodarone; Atrial Fibrillation; Heart Rate; Humans; Recurrence; Stroke; Warfarin	2005
[Adverse effects of cardiovascular agents]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Brugada Syndrome; Drug Interactions; Fibrinolytic Agents; Hemorrhage; Heparin; Humans; Long QT Syndrome; Lung Diseases, Interstitial; Platelet Aggregation Inhibitors; Thrombocytopenia; Vasodilator Agents; Warfarin	2007
Atrial fibrillation in heart failure: the chicken or the egg? Heart (British Cardiac Society), 2009, Volume: 95, Issue:7 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Catheter Ablation; Electrocardiography; Heart Failure; Humans; Middle Aged; Warfarin	2009
Dronedarone and vitamin K antagonists: a review of drug-drug interactions. American heart journal, 2010, Volume: 160, Issue:4 Topics: Amiodarone; Anticoagulants; Atrial Fibrillation; Dronedarone; Drug Interactions; Drug Therapy, Combination; Humans; Vitamin K; Warfarin	2010
Atrial fibrillation: new drugs, devices, and procedures. Cleveland Clinic journal of medicine, 2012, Volume: 79, Issue:8 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Catheter Ablation; Dronedarone; Equipment and Supplies; Humans; Warfarin	2012
Stroke prevention in atrial fibrillation: concepts and controversies. Current cardiology reviews, 2012, Volume: 8, Issue:4 Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clinical Trials, Phase III as Topic; Dabigatran; Dronedarone; Drug Design; Humans; Morpholines; Pyrazoles; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Thiophenes; Treatment Outcome; Warfarin	2012
Use of medication for cardiovascular disease during pregnancy. Nature reviews. Cardiology, 2015, Volume: 12, Issue:12 Topics: Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Female; Humans; Pregnancy; Pregnancy Complications, Cardiovascular; Spironolactone; Warfarin	2015
Are Evidence Standards Different for Genomic- vs. Clinical-Based Precision Medicine? A Quantitative Analysis of Individualized Warfarin Therapy. Clinical pharmacology and therapeutics, 2017, Volume: 102, Issue:5 Topics: Amiodarone; Anticoagulants; Drug Interactions; Genomics; Humans; Pharmacogenetics; Precision Medicine; Randomized Controlled Trials as Topic; Warfarin	2017
Clinical outcomes in patients with atrial fibrillation receiving amiodarone on NOACs vs. warfarin. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2019, Volume: 54, Issue:1 Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Stroke; Survival Rate; Thromboembolism; Treatment Outcome; Warfarin	2019
Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Versus Warfarin in Patients with Atrial Fibrillation Using P-gp and/or CYP450-Interacting Drugs: a Systematic Review and Meta-analysis. Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:4 Topics: Administration, Oral; Amiodarone; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Atrial Fibrillation; Cytochrome P-450 CYP3A Inhibitors; Embolism; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; Stroke; Warfarin	2023

Trials

7 trial(s) available for amiodarone and warfarin

Article	Year
Role of desethylamiodarone in the anticoagulant effect of concurrent amiodarone and warfarin therapy. Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:4 Topics: Adult; Aged; Amiodarone; Anticoagulants; Drug Interactions; Drug Therapy, Combination; Female; Heart Diseases; Humans; International Normalized Ratio; Male; Middle Aged; Warfarin	2001
Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. JAMA, 2002, Dec-25, Volume: 288, Issue:24 Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cardiovascular Agents; Catheter Ablation; Defibrillators, Implantable; Digoxin; Diuretics; Female; Heart Failure; Humans; Male; Middle Aged; Pacemaker, Artificial; Single-Blind Method; Survival Analysis; Tachycardia, Ventricular; Ventricular Dysfunction, Left; Warfarin	2002
Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation, 2004, Mar-30, Volume: 109, Issue:12 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Combined Modality Therapy; Comorbidity; Digoxin; Electric Countershock; Follow-Up Studies; Heart Rate; Humans; Models, Cardiovascular; Myocardial Contraction; Phenethylamines; Proportional Hazards Models; Retrospective Studies; Risk; Stroke; Sulfonamides; Survival Analysis; Treatment Failure; Treatment Outcome; Warfarin	2004
Factors affecting bleeding risk during anticoagulant therapy in patients with atrial fibrillation: observations from the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study. American heart journal, 2005, Volume: 149, Issue:4 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; Combined Modality Therapy; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Life Tables; Male; Middle Aged; Risk; Stroke; Thromboembolism; Warfarin	2005
The influence of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose. European journal of clinical pharmacology, 2006, Volume: 62, Issue:4 Topics: Aged; Aged, 80 and over; Amiodarone; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP2C9; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pharmacokinetics; Warfarin	2006
Amiodarone, anticoagulation, and clinical events in patients with atrial fibrillation: insights from the ARISTOTLE trial. Journal of the American College of Cardiology, 2014, Oct-14, Volume: 64, Issue:15 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Brazil; Cause of Death; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Europe; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Ontario; Pyrazoles; Pyridones; Stroke; Survival Rate; Thromboembolism; Treatment Outcome; United States; Warfarin	2014
Edoxaban vs. warfarin in patients with atrial fibrillation on amiodarone: a subgroup analysis of the ENGAGE AF-TIMI 48 trial. European heart journal, 2015, Sep-01, Volume: 36, Issue:33 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin	2015

Other Studies

86 other study(ies) available for amiodarone and warfarin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Development of Robust 17( Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar	2019
The mechanism of the interaction between amiodarone and warfarin in humans. Clinical pharmacology and therapeutics, 1992, Volume: 51, Issue:4 Topics: Adult; Amiodarone; Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolic Clearance Rate; Microsomes, Liver; Stereoisomerism; Warfarin	1992
Side effects and complications of amiodarone therapy. American heart journal, 1985, Volume: 109, Issue:5 Pt 1 Topics: Amiodarone; Arrhythmias, Cardiac; Ataxia; Benzofurans; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Respiratory Tract Diseases; Thyroid Diseases; Time Factors; Vision Disorders; Warfarin	1985
The incidence, magnitude, and time course of the amiodarone-warfarin interaction. Archives of internal medicine, 1988, Volume: 148, Issue:8 Topics: Amiodarone; Drug Synergism; Female; Humans; Male; Middle Aged; Prothrombin Time; Retrospective Studies; Time Factors; Warfarin	1988
Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:3 Topics: Adult; Amiodarone; Drug Interactions; Humans; Kinetics; Male; Prothrombin Time; Stereoisomerism; Warfarin	1987
In vitro amiodarone protein binding and its interaction with warfarin. Experientia, 1985, Mar-15, Volume: 41, Issue:3 Topics: Amiodarone; Benzofurans; Binding Sites; Binding, Competitive; Blood Proteins; Dialysis; Humans; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Ultracentrifugation; Warfarin	1985
Mechanism of warfarin potentiation by amiodarone: dose--and concentration--dependent inhibition of warfarin elimination. European journal of clinical pharmacology, 1985, Volume: 28, Issue:3 Topics: Adult; Aged; Amiodarone; Benzofurans; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Female; Humans; Male; Middle Aged; Warfarin	1985
Amiodarone reduces plasma warfarin clearance in man. British journal of clinical pharmacology, 1985, Volume: 20, Issue:6 Topics: Aged; Amiodarone; Benzofurans; Blood Proteins; Female; Humans; Male; Middle Aged; Protein Binding; Warfarin	1985
Drug interactions with amiodarone. American heart journal, 1983, Volume: 106, Issue:4 Pt 2 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Benzofurans; Blood Coagulation Disorders; Calcium; Digoxin; Drug Interactions; Drug Synergism; Heart Arrest; Humans; Kinetics; Quinidine; Tachycardia; Warfarin	1983
Binding of amiodarone by serum proteins and the effects of drugs, hormones and other interacting ligands. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:6 Topics: Amiodarone; Benzofurans; Binding, Competitive; Blood Proteins; Digoxin; Drug Interactions; Humans; In Vitro Techniques; Ligands; Protein Binding; Serum Albumin; Thyronines; Warfarin	1984
Efficacy and safety of long-term amiodarone in treatment of cardiac arrhythmias: dosage experience. American heart journal, 1983, Volume: 106, Issue:4 Pt 2 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Blood Coagulation Disorders; Dose-Response Relationship, Drug; Drug Interactions; Heart Atria; Heart Ventricles; Humans; Tachycardia; Warfarin	1983
Evaluation of amiodarone therapy in the treatment of drug-resistant cardiac arrhythmias: long-term follow-up. American heart journal, 1983, Volume: 106, Issue:4 Pt 2 Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Female; Follow-Up Studies; Humans; Male; Middle Aged; Warfarin	1983
Dangers of amiodarone and anticoagulant treatment. British medical journal (Clinical research ed.), 1981, May-30, Volume: 282, Issue:6278 Topics: Amiodarone; Animals; Benzofurans; Drug Interactions; Female; Humans; Middle Aged; Prothrombin Time; Rabbits; Warfarin	1981
Dangers of amiodarone and anticoagulant treatment. British medical journal (Clinical research ed.), 1981, Jul-04, Volume: 283, Issue:6283 Topics: Aged; Amiodarone; Benzofurans; Drug Interactions; Humans; Male; Myocardial Infarction; Prothrombin Time; Warfarin	1981
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
The potentiation of warfarin anticoagulation by amiodarone. Circulation, 1982, Volume: 65, Issue:5 Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Blood Coagulation; Blood Coagulation Factors; Drug Synergism; Female; Humans; Male; Middle Aged; Prothrombin Time; Vitamin K; Warfarin	1982
Interaction between warfarin sodium and amiodarone. The New England journal of medicine, 1981, Mar-12, Volume: 304, Issue:11 Topics: Amiodarone; Benzofurans; Drug Synergism; Humans; Prothrombin Time; Warfarin	1981
Insidiously evolving, occult drug interaction involving warfarin and amiodarone. BMJ (Clinical research ed.), 1996, Jan-13, Volume: 312, Issue:7023 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Blood Coagulation Disorders; Drug Interactions; Hematuria; Humans; Male; Prothrombin Time; Warfarin	1996
Monitoring may need to be prolonged in patients given warfarin and amiodarone. BMJ (Clinical research ed.), 1996, Aug-03, Volume: 313, Issue:7052 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Asian People; China; Drug Interactions; Hong Kong; Humans; Warfarin	1996
Cardioversion of atrial fibrillation. Postgraduate medical journal, 1996, Volume: 72, Issue:844 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Electric Countershock; Humans; Warfarin	1996
Cardiac memory: a mechanical and electrical phenomenon. The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atenolol; Cardiomyopathy, Hypertrophic; Diastole; Echocardiography; Electrocardiography; Equipment Design; Female; Heart; Humans; Male; Memory; Middle Aged; Models, Cardiovascular; Pacemaker, Artificial; Sotalol; Time Factors; Ventricular Function, Left; Warfarin	1997
Potentiation of warfarin sodium by amiodarone-induced thyrotoxicosis. The Western journal of medicine, 1999, Volume: 170, Issue:1 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Drug Synergism; Humans; International Normalized Ratio; Male; Prothrombin Time; Tachycardia, Supraventricular; Thyrotoxicosis; Thyroxine; Warfarin	1999
Heart failure: a diagnostic and therapeutic dilemma in elderly patients. Age and ageing, 1999, Volume: 28, Issue:3 Topics: Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Clinical Trials as Topic; Death, Sudden, Cardiac; Defibrillators, Implantable; Heart Failure; Humans; Myocardial Infarction; Warfarin	1999
Lack of prevention of heart failure by serial electrical cardioversion in patients with persistent atrial fibrillation. Heart (British Cardiac Society), 1999, Volume: 82, Issue:4 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Electric Countershock; Female; Flecainide; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Risk; Sotalol; Treatment Failure; Warfarin	1999
Amiodarone in atrial fibrillation. Postgraduate medical journal, 1999, Volume: 75, Issue:889 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Female; Humans; Male; Warfarin	1999
Amiodarone to prevent recurrence of atrial fibrillation. The New England journal of medicine, 2000, Aug-24, Volume: 343, Issue:8 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Digoxin; Drug Approval; Drug Interactions; Humans; Secondary Prevention; Warfarin	2000
Bleeding complication during coumarin therapy due to amiodarone and azithromycin. The Journal of the Association of Physicians of India, 2000, Volume: 48, Issue:7 Topics: Amiodarone; Anticoagulants; Atrial Fibrillation; Azithromycin; Coumarins; Drug Interactions; Fatal Outcome; Female; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; Middle Aged; Postoperative Complications; Respiratory Tract Infections	2000
Clinical observations with the amiodarone/warfarin interaction: dosing relationships with long-term therapy. Chest, 2002, Volume: 121, Issue:1 Topics: Aged; Amiodarone; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Heart Diseases; Hemorrhage; Humans; Long-Term Care; Male; Middle Aged; Retrospective Studies; Risk Factors; Tachycardia; Warfarin	2002
Factors affecting warfarin therapy following cardiac valve surgery. The Annals of pharmacotherapy, 2002, Volume: 36, Issue:12 Topics: Adult; Amiodarone; Anticoagulants; Dose-Response Relationship, Drug; Drug Interactions; Ethnicity; Female; Heart Valve Diseases; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; International Normalized Ratio; Korea; Male; Retrospective Studies; Warfarin	2002
Interactions between amiodarone and vitamin K antagonists. Prescrire international, 2003, Volume: 12, Issue:64 Topics: Amiodarone; Anticoagulants; Drug Interactions; France; Hemorrhage; Humans; Vitamin K; Warfarin	2003
[Long-term drug interaction of warfarin with amiodarone]. Casopis lekaru ceskych, 2003, Jan-20, Volume: 142, Issue:1 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Drug Interactions; Hemorrhage; Humans; Intracranial Thrombosis; Male; Warfarin	2003
[Excess antivitamin K in elderly hospitalised patients aged over 70. A one-year prospective survey]. Presse medicale (Paris, France : 1983), 2003, Jun-14, Volume: 32, Issue:21 Topics: 4-Hydroxycoumarins; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Coma; Drug Administration Schedule; Drug Overdose; Drug Synergism; Female; Hematoma, Subdural; Hemorrhage; Hospitalization; Humans; Indenes; International Normalized Ratio; Male; Prospective Studies; Pulmonary Embolism; Thrombocytopenia; Vitamin K; Warfarin	2003
[Arrhythmogenic dilated cardiomyopathy]. Medicina (Kaunas, Lithuania), 2003, Volume: 39, Issue:7 Topics: Adult; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anticoagulants; Antihypertensive Agents; Atrial Fibrillation; Cardiomyopathy, Dilated; Echocardiography; Electric Countershock; Electrocardiography; Follow-Up Studies; Humans; Male; Ramipril; Time Factors; Warfarin	2003
Left atrial thrombus formation early after mitral valve replacement. Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiac Output, Low; Echocardiography, Doppler; Echocardiography, Transesophageal; Electrocardiography; Female; Heart Atria; Heart Diseases; Heart Valve Prosthesis Implantation; Heparin; Humans; Hypotension; Middle Aged; Mitral Valve; Postoperative Complications; Thrombosis; Time Factors; Warfarin	2004
Simultaneous double external DC shock technique for refractory atrial fibrillation in concomitant heart disease. Japanese heart journal, 2004, Volume: 45, Issue:6 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Defibrillators; Electric Countershock; Humans; Middle Aged; Mitral Valve Insufficiency; Rheumatic Heart Disease; Warfarin	2004
Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison. Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:9 Topics: Amiodarone; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; DNA, Complementary; Ethanolamines; Female; Humans; Kinetics; Lauric Acids; Male; Mephenytoin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrophenols; Oxidoreductases, N-Demethylating; Oxygen; Paclitaxel; Phenacetin; Rats; Sex Factors; Species Specificity; Substrate Specificity; Testosterone	2004
Chagas disease is an independent risk factor for stroke: baseline characteristics of a Chagas Disease cohort. Stroke, 2005, Volume: 36, Issue:9 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Chagas Disease; Cohort Studies; Female; Heart Diseases; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Platelet Aggregation Inhibitors; Regression Analysis; Risk Factors; Stroke; Warfarin	2005
Combined atrial fibrillation ablation with mitral valve surgery. The Journal of heart valve disease, 2006, Volume: 15, Issue:4 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Catheter Ablation; Evaluation Studies as Topic; Female; Follow-Up Studies; Heart Atria; Heart Valve Prosthesis Implantation; Humans; Male; Middle Aged; Mitral Valve; Postoperative Period; Retrospective Studies; Time Factors; Treatment Outcome; Warfarin	2006
Amiodarone for atrial fibrillation. The New England journal of medicine, 2007, Jun-07, Volume: 356, Issue:23 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Humans; International Normalized Ratio; Thyroid Diseases; Thyrotoxicosis; Warfarin	2007
Impact of thyroid metabolism on the course of INR levels in a patient with systemic anticoagulation suffering from amiodarone-induced thyrotoxicosis. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2007, Volume: 115, Issue:9 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Coumarins; Female; Humans; International Normalized Ratio; Middle Aged; Thyroid Gland; Thyrotoxicosis; Thyrotropin; Thyroxine; Triiodothyronine; Ventricular Premature Complexes	2007
Characteristics of the amiodarone-warfarin interaction during long-term follow-up. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, May-15, Volume: 65, Issue:10 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Retrospective Studies; Warfarin	2008
Pharmacogenetics of warfarin: development of a dosing algorithm for brazilian patients. Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Ambulatory Care; Amiodarone; Analysis of Variance; Aryl Hydrocarbon Hydroxylases; Brazil; Cohort Studies; Cytochrome P-450 CYP2C9; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ethnicity; Female; Genotype; Humans; Linear Models; Male; Middle Aged; Mixed Function Oxygenases; Multivariate Analysis; Pharmacogenetics; Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Simvastatin; Treatment Outcome; Vitamin K Epoxide Reductases; Warfarin; Young Adult	2008
I was told to stop taking my daily betablocker (Coreg)before a myocardial perfusion test. I was hospitalized with chest pain and a bout of atrial fibrillation. I have cardiomyopathy and was prescribed amiodarone and warfarin, but I stopped taking them w Heart advisor, 2008, Volume: 11, Issue:8 Topics: Adrenergic beta-Antagonists; Amiodarone; Anticoagulants; Atrial Fibrillation; Cardiomyopathies; Chest Pain; Humans; Perfusion; Vasodilator Agents; Warfarin	2008
Effect of tecarfarin, a novel vitamin K epoxide reductase inhibitor, on coagulation in beagle dogs. British journal of pharmacology, 2009, Volume: 158, Issue:6 Topics: Administration, Oral; Amiodarone; Animals; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Benzoates; Coumarins; Cytochrome P-450 CYP2C9; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Factor VII; Factor X; Female; Infusions, Intravenous; Male; Mixed Function Oxygenases; Prothrombin Time; Vitamin K Epoxide Reductases; Warfarin	2009
An evaluation of the early pharmacodynamic response after simultaneous initiation of warfarin and amiodarone. Journal of clinical pharmacology, 2010, Volume: 50, Issue:6 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; International Normalized Ratio; Male; Retrospective Studies; Time Factors; Warfarin	2010
An important indirect drug interaction between dronedarone and warfarin that may be extrapolated to other drugs that can alter gastrointestinal function. American heart journal, 2011, Volume: 161, Issue:2 Topics: Amiodarone; Anticoagulants; Dronedarone; Drug Interactions; Gastrointestinal Tract; Humans; Warfarin	2011
Elevated international normalized ratio associated with use of dronedarone and warfarin. The Annals of pharmacotherapy, 2011, Volume: 45, Issue:9 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Dose-Response Relationship, Drug; Dronedarone; Drug Interactions; Drug Monitoring; Female; Humans; International Normalized Ratio; Warfarin	2011
Warfarin-amiodarone drug-drug interactions: determination of [I](u)/K(I,u) for amiodarone and its plasma metabolites. Clinical pharmacology and therapeutics, 2012, Volume: 91, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Chromatography, Liquid; Cohort Studies; Drug Interactions; Female; Humans; Male; Middle Aged; Retrospective Studies; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Warfarin; Young Adult	2012
[Update on current care guidelines: atrial fibrillation]. Duodecim; laaketieteellinen aikakauskirja, 2012, Volume: 128, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Dronedarone; Finland; Humans; Morpholines; Practice Guidelines as Topic; Rivaroxaban; Thiophenes; Warfarin	2012
Genetic resistance to warfarin therapy masked by amiodarone in a 2-year-old girl with mitral valve replacement. Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:3 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Blood Coagulation; Child, Preschool; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Drug Resistance; Female; Genotype; Heart Valve Prosthesis Implantation; Humans; International Normalized Ratio; Mitral Valve Stenosis; Mixed Function Oxygenases; Phenotype; Polymorphism, Single Nucleotide; Vitamin K Epoxide Reductases; Warfarin	2013
Hospitalized patients with atrial fibrillation compared to those included in recent trials on novel oral anticoagulants: a population-based study. European journal of internal medicine, 2013, Volume: 24, Issue:4 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Cohort Studies; Female; Fibrinolytic Agents; Hospitalization; Humans; Male; Platelet Aggregation Inhibitors; Polypharmacy; Stroke; Warfarin	2013
Hospitalization for hemorrhage among warfarin recipients prescribed amiodarone. The American journal of cardiology, 2013, Aug-01, Volume: 112, Issue:3 Topics: Aged; Algorithms; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Cohort Studies; Drug Synergism; Drug Therapy, Combination; Female; Hemorrhage; Hospital Mortality; Hospitalization; Humans; Male; Ontario; Retrospective Studies; Warfarin	2013
Myxedema coma induced by short-term amiodarone therapy. The American journal of the medical sciences, 2014, Volume: 347, Issue:3 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Coma; Drug Interactions; Humans; Male; Myxedema; Warfarin	2014
Simultaneous use of amiodarone influences warfarin maintenance dose but is not associated with adverse events. Journal of managed care & specialty pharmacy, 2014, Volume: 20, Issue:4 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Cohort Studies; Cytochrome P-450 CYP2C9; Dose-Response Relationship, Drug; Female; Genotype; Humans; International Normalized Ratio; Male; Middle Aged; Polymorphism, Genetic; Prothrombin Time; Retrospective Studies; Vitamin K Epoxide Reductases; Warfarin	2014
[The clinical analysis of atrial fibrillation of 1 310 in patients in Urumqi of China]. Zhonghua nei ke za zhi, 2014, Volume: 53, Issue:5 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atrial Fibrillation; China; Comorbidity; Diabetes Mellitus; Factor Xa Inhibitors; Female; Fibrinolytic Agents; Humans; Hypertension; Incidence; Inpatients; Male; Morpholines; Retrospective Studies; Rivaroxaban; Stroke; Thiophenes; Treatment Outcome; Warfarin	2014
Amiodarone use is associated with increased risk of stroke in patients with nonvalvular atrial fibrillation: a nationwide population-based cohort study. Medicine, 2015, Volume: 94, Issue:19 Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Comorbidity; Digoxin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Stroke; Taiwan; Warfarin	2015
Edoxaban and amiodarone: interactions on multiple levels. European heart journal, 2015, Sep-01, Volume: 36, Issue:33 Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Female; Humans; Male; Pyridines; Thiazoles; Warfarin	2015
The effect of the amiodarone-warfarin interaction on anticoagulation quality in a single, high-quality anticoagulation center. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:2 Topics: Aged; Aged, 80 and over; Amiodarone; Anticoagulants; Atrial Fibrillation; Drug Combinations; Female; Follow-Up Studies; Humans; International Normalized Ratio; Male; Middle Aged; Sex Factors; Smoking; Thromboembolism; Time Factors; Treatment Outcome; Warfarin	2016
Phenotypic and biomarker evaluation of zebrafish larvae as an alternative model to predict mammalian hepatotoxicity. Journal of applied toxicology : JAT, 2016, Volume: 36, Issue:9 Topics: Acetaminophen; Amiodarone; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Ceruloplasmin; Coumarins; Female; Gene Expression Regulation; Genetic Markers; Genome-Wide Association Study; Humans; In Situ Hybridization; Larva; Liver; Male; Methapyrilene; Nitriles; Oxidoreductases, N-Demethylating; Phenotype; Toxicity Tests; Transferrin; Triazoles; Zebrafish; Zebrafish Proteins	2016
Study of warfarin utilization in hospitalized patients: analysis of possible drug interactions. International journal of clinical pharmacy, 2016, Volume: 38, Issue:5 Topics: Adult; Aged; Amiodarone; Anticoagulants; Aspirin; Brazil; Cross-Sectional Studies; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Hospitalization; Humans; Male; Middle Aged; Tertiary Care Centers; Warfarin	2016
Triple Oral Antithrombotic Therapy: A Teachable Moment. JAMA internal medicine, 2016, 10-01, Volume: 176, Issue:10 Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chest Pain; Coronary Artery Disease; Drug-Eluting Stents; Fibrinolytic Agents; Heart Failure; Humans; Hypertension; Male; Platelet Aggregation Inhibitors; Renal Insufficiency, Chronic; Tachycardia, Ventricular; Treatment Outcome; Warfarin	2016
The effect of amiodarone on warfarin anticoagulation: a register-based nationwide cohort study involving the Swedish population. Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Blood Coagulation; Cohort Studies; Dose-Response Relationship, Drug; Drug Monitoring; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Registries; Retrospective Studies; Sweden; Warfarin; Young Adult	2017
Population Impact of Drug Interactions with Warfarin: A Real-World Data Approach. Thrombosis and haemostasis, 2018, Volume: 118, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anticoagulants; Carbamazepine; Databases, Factual; Drug Interactions; Female; Fluconazole; Follow-Up Studies; Humans; International Normalized Ratio; Male; Miconazole; Middle Aged; Nystatin; Primary Health Care; Retrospective Studies; United Kingdom; Warfarin; Young Adult	2018
Assessment of warfarin algorithms for hospitalized adults: searching for a safe dosing strategy. Journal of thrombosis and thrombolysis, 2019, Volume: 48, Issue:4 Topics: Aged; Aged, 80 and over; Algorithms; Amiodarone; Drug Dosage Calculations; Female; Hospitalization; Humans; International Normalized Ratio; Male; Retrospective Studies; Warfarin	2019
The Magnitude of the Warfarin-Amiodarone Drug-Drug Interaction Varies With Renal Function: A Propensity-Matched Cohort Study. Clinical pharmacology and therapeutics, 2020, Volume: 107, Issue:6 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cohort Studies; Drug Interactions; Female; Hemorrhage; Hospitalization; Humans; International Normalized Ratio; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Retrospective Studies; Warfarin	2020
Assessment of practices for suspended oral drugs by tablet crushing in pediatric units. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2020, Volume: 157 Topics: Administration, Oral; Age Factors; Amiodarone; Captopril; Drug Compounding; Drug Dosage Calculations; Drugs, Generic; Humans; Hydrocortisone; Pediatrics; Pharmaceutical Preparations; Pharmaceutical Solutions; Quality Control; Solubility; Tablets; Warfarin	2020
Patterns of Care for Atrial Fibrillation Before, During, and at Discharge From Hospitalization: From the Get With The Guidelines-Atrial Fibrillation Registry. Circulation. Arrhythmia and electrophysiology, 2021, Volume: 14, Issue:4 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Catheter Ablation; Drug Substitution; Drug Utilization; Electric Countershock; Factor Xa Inhibitors; Female; Hospitalization; Humans; Male; Middle Aged; Patient Admission; Patient Discharge; Practice Patterns, Physicians'; Prevalence; Registries; Time Factors; Treatment Outcome; United States; Warfarin	2021
Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin. European journal of clinical pharmacology, 2022, Volume: 78, Issue:2 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Apolipoproteins E; Asian People; Body Surface Area; Body Weight; China; Cytochrome P-450 Enzyme Inhibitors; Ethnicity; Female; Genotype; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Sociodemographic Factors; Warfarin	2022
[Significant Prolongation of the International Normalized Ratio Associated with COVID-19 Treatment: Possible Drug Interaction with Remdesivir]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2022, Volume: 142, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amiodarone; Anticoagulants; Atorvastatin; Bisoprolol; COVID-19 Drug Treatment; Dexamethasone; Diltiazem; Drug Interactions; Humans; International Normalized Ratio; Male; Middle Aged; Warfarin	2022
Postoperative Atrial Fibrillation After Surgical Aortic Valve Replacement: Amiodarone and Warfarin Use. The Journal of surgical research, 2023, Volume: 291 Topics: Amiodarone; Anticoagulants; Aortic Valve; Atrial Fibrillation; Humans; Postoperative Complications; Retrospective Studies; Risk Factors; Treatment Outcome; Warfarin	2023