amiodarone and uk 68798

amiodarone has been researched along with uk 68798 in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (6.90)	18.2507
2000's	37 (63.79)	29.6817
2010's	15 (25.86)	24.3611
2020's	2 (3.45)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Keserü, GM	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Honerjäger, P; Schmidt, G	1
Bharucha, D; Kowey, PR; Marinchak, RA; Rials, SJ	1
Beyer, ME; Hoffmeister, HM; Seipel, L	1
MacNeil, DJ	1
Sager, PT	1
Alboni, P; Bianconi, L; Castro, A; Dinelli, M; Pappalardo, A; Richiardi, E; Santini, M	1
Schmitt, C	1
Knobloch, K; Wirth, KJ	1
Camm, AJ	1
Ahn, S; Etienne, J; Friedrich, T; Ghadanfar, M; Massart, PE; Pouleur, H; Rousseau, MF; van Eyll, C	1
Dai, DZ; Kong, RZ; Li, HT; Wang, YQ	1
Cox, CD; Tsikouris, JP	1
Bianconi, L; Castro, A; Santini, M	1
Cleland, JG; Deedwania, PC; Khand, AU	1
Singh, BN	1
Nattel, S; Schram, G; Shinagawa, K; Shiroshita-Takeshita, A	1
Bhatta, L; Hynes, J; Khan, M; Luck, J; Naccarelli, GV; Samii, S; Wolbrette, DL	1
Kao, W; Kowey, PR; Winkel, E; Yan, GX	1
Wolbrette, DL	1
DeBisschop, M; Lower, DL; Martin, LG; Yamreudeewong, W	1
Khan, MH	1
Li, WZ	1
Singh, S	1
Mounsey, JP; VerNooy, RA	1
Prystowsky, EN	1
Corley, SD; DiMarco, JP; Domanski, MJ; Epstein, AE; Geller, N; Greene, HL; Josephson, RA; Kellen, JC; Klein, RC; Krahn, AD; Mickel, M; Mitchell, LB; Nelson, JD; Rosenberg, Y; Schron, E; Shemanski, L; Waldo, AL; Wyse, DG	1
Bleich, M; Brendel, J; Busch, AE; Knobloch, K; Rosenstein, B; Wirth, KJ	1
Brendorp, B; Elming, H; Køber, L; Pedersen, OD; Pehrson, S; Torp-Petersen, C	1
Cvetanovic, I; Ke, X; Lin, C; Ranade, V; Somberg, J	1
Bhatia, GS; Lip, GY	1
Hamlin, RL; Keene, BW; Kijtawornrat, A; Nishijima, Y; Roche, BM	1
Bauman, JL; Kehoe, RF; Leal, S; Mykytsey, A; Razminia, M; Saleem, M; Wang, T; Zheutlin, T	1
Afkham, F; Itter, G; Linz, DK; Rütten, H; Wirth, KJ	1
London, B	1
Verma, A	1
Ahmad, K; Akhtari, S; Dorian, P; Korley, V; Mangat, I; Newman, D; O'Connell, T; O'Donnell, S; Pinter, A; Posan, E	1
DU, CY; El Harchi, A; Hancox, JC; Orchard, CH; Zhang, YH	1
Saklani, P; Skanes, A	1
Anderson, JL; Bunch, TJ	1
Adelstein, E; Alam, MB; Jain, SK; Khattak, F; Leef, G; Munir, MB; Patel, D; Qin, D; Rattan, R; Saba, S	1
Abildgaard, L; Diness, JG; Grunnet, M; Jespersen, T; Kirchhoff, JE; Sheykhzade, M	1
Dick, T; Negrelli, J; Olson, JL; Rickard, JP	1
Atkins, D; Bommana, S; Carroll, H; Gopinathannair, R; Jeffrey, C; Lakkireddy, D; Natale, A; Newton, D; Nydegger, C; Sharma, SP; Turagam, M	1
Árpádffy-Lovas, T; Baczkó, I; Husti, Z; Varró, A; Virág, L	1
Batul, A; Bogun, F; Chugh, A; Chung, E; Crawford, T; Cunnane, R; Ghanbari, H; Ghannam, M; Jongnarangsin, K; Latchamsetty, R; Liang, J; Morady, F; Oral, H; Pelosi, F; Saeed, M; Shantha, G	1

Reviews

21 review(s) available for amiodarone and uk 68798

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[New anti-arrhythmia agents]. Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Phenethylamines; Procainamide; Propanolamines; Sotalol; Sulfonamides; Survival Rate; Tachycardia	1992
Pharmacologic and pharmacokinetic profile of class III antiarrhythmic drugs. The American journal of cardiology, 1997, Oct-23, Volume: 80, Issue:8A Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Humans; Phenethylamines; Sotalol; Sulfonamides	1997
The side effect profile of class III antiarrhythmic drugs: focus on d,l-sotalol. The American journal of cardiology, 1997, Oct-23, Volume: 80, Issue:8A Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Conduction System; Heart Failure; Humans; Hypertension; Infant, Newborn; Phenethylamines; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Exposure Delayed Effects; Risk Factors; Sotalol; Sulfonamides; Survival Rate; Torsades de Pointes	1997
New advances in class III antiarrhythmic drug therapy. Current opinion in cardiology, 2000, Volume: 15, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2000
Clinical differences between the newer antiarrhythmic agents. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2000, Volume: 1 Suppl C Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2000
A review of class III antiarrhythmic agents for atrial fibrillation: maintenance of normal sinus rhythm. Pharmacotherapy, 2001, Volume: 21, Issue:12 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Drug Interactions; Humans; Phenethylamines; Sotalol; Sulfonamides	2001
New antiarrhythmic drugs for the treatment of atrial fibrillation. Pacing and clinical electrophysiology : PACE, 2002, Volume: 25, Issue:2 Topics: Aminobenzoates; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2002
Prevention of and medical therapy for atrial arrhythmias in heart failure. Heart failure reviews, 2002, Volume: 7, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Carbazoles; Carvedilol; Drug Therapy, Combination; Electric Countershock; Heart Failure; Humans; Pacemaker, Artificial; Phenethylamines; Propanolamines; Software Design; Sulfonamides	2002
Significance and control of cardiac arrhythmias in patients with congestive cardiac failure. Heart failure reviews, 2002, Volume: 7, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Death, Sudden, Cardiac; Defibrillators, Implantable; Drug Therapy, Combination; Heart Failure; Humans; Phenethylamines; Sulfonamides; Tachycardia, Ventricular; Ventricular Fibrillation	2002
Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Australia; Canada; Controlled Clinical Trials as Topic; Europe; Flecainide; Heart Conduction System; Heart Failure; Humans; Multicenter Studies as Topic; Myocardial Infarction; Phenethylamines; Propafenone; Quinidine; Sotalol; Sulfonamides; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; United States	2003
Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Flecainide; Heart Rate; Humans; Phenethylamines; Practice Guidelines as Topic; Propafenone; Quinidine; Stroke; Sulfonamides; Ventricular Dysfunction, Left	2003
Risk of proarrhythmia with class III antiarrhythmic agents: sex-based differences and other issues. The American journal of cardiology, 2003, Mar-20, Volume: 91, Issue:6A Topics: Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Female; Heart Conduction System; Humans; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Risk Assessment; Risk Factors; Sex Factors; Sotalol; Sulfonamides; Tachycardia; Torsades de Pointes	2003
Potentially significant drug interactions of class III antiarrhythmic drugs. Drug safety, 2003, Volume: 26, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Drug Interactions; Humans; Phenethylamines; Sotalol; Sulfonamides	2003
Oral class III antiarrhythmics: what is new? Current opinion in cardiology, 2004, Volume: 19, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sotalol; Sulfonamides; Tachycardia, Supraventricular; Tachycardia, Ventricular; Treatment Outcome	2004
Trials of new antiarrhythmic drugs for maintenance of sinus rhythm in patients with atrial fibrillation. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2004, Volume: 10 Suppl 1 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Cyclopropanes; Dronedarone; Humans; Hydantoins; Imidazoles; Imidazolidines; Indoles; Oxazines; Phenethylamines; Piperazines; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides	2004
Antiarrhythmic drug therapy of atrial fibrillation. Cardiology clinics, 2004, Volume: 22, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Flecainide; Humans; Phenethylamines; Sotalol; Sulfonamides	2004
A benefit-risk assessment of class III antiarrhythmic agents. Expert opinion on drug safety, 2004, Volume: 3, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Combined Modality Therapy; Defibrillators, Implantable; Dronedarone; Heart Conduction System; Humans; Hydantoins; Imidazolidines; Ion Transport; Life Tables; Membrane Potentials; Meta-Analysis as Topic; Phenethylamines; Piperazines; Risk Assessment; Sotalol; Sulfonamides; Survival Analysis; Torsades de Pointes; Treatment Outcome	2004
Atrial fibrillation post-myocardial infarction: frequency, consequences, and management. Current heart failure reports, 2004, Volume: 1, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Heart Failure; Humans; Incidence; Myocardial Infarction; Phenethylamines; Potassium Channel Blockers; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Sulfonamides	2004
Novel anti-arrhythmic medications in the treatment of atrial fibrillation. Current cardiology reviews, 2012, Volume: 8, Issue:4 Topics: Acetanilides; Amiodarone; Anisoles; Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Digoxin; Dronedarone; Forecasting; Heart Failure; Humans; Phenethylamines; Piperazines; Pyrrolidines; Ranolazine; Sulfonamides; Technology, Pharmaceutical; Ventricular Dysfunction, Left	2012
Adjuvant antiarrhythmic therapy in patients with implantable cardioverter defibrillators. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:2 Topics: Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Benzofurans; Defibrillators, Implantable; Humans; Hydantoins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazolidines; Mineralocorticoid Receptor Antagonists; Phenethylamines; Piperazines; Sotalol; Sulfonamides	2014

Trials

4 trial(s) available for amiodarone and uk 68798

Article	Year
Comparison of intravenously administered dofetilide versus amiodarone in the acute termination of atrial fibrillation and flutter. A multicentre, randomized, double-blind, placebo-controlled study. European heart journal, 2000, Volume: 21, Issue:15 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Blood Pressure; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Phenethylamines; Potassium Channel Blockers; Prognosis; Sulfonamides; Vasodilator Agents	2000
Cardiac and hemodynamic effects of intravenous dofetilide in patients with heart failure. The American journal of cardiology, 2001, Jun-01, Volume: 87, Issue:11 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Double-Blind Method; Electrocardiography; Female; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Long QT Syndrome; Male; Middle Aged; Myocardial Contraction; Phenethylamines; Sulfonamides; Ventricular Function, Left	2001
Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study. Circulation, 2004, Mar-30, Volume: 109, Issue:12 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Combined Modality Therapy; Comorbidity; Digoxin; Electric Countershock; Follow-Up Studies; Heart Rate; Humans; Models, Cardiovascular; Myocardial Contraction; Phenethylamines; Proportional Hazards Models; Retrospective Studies; Risk; Stroke; Sulfonamides; Survival Analysis; Treatment Failure; Treatment Outcome; Warfarin	2004
Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function. Journal of cardiovascular pharmacology and therapeutics, 2007, Volume: 12, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Dose-Response Relationship, Drug; Drug Monitoring; Female; Flecainide; Follow-Up Studies; Humans; Inpatients; Long QT Syndrome; Male; Middle Aged; Phenethylamines; Propafenone; Recurrence; Sotalol; Sulfonamides; Tachycardia, Ventricular; Treatment Outcome; Ventricular Function, Left; Withholding Treatment	2007

Other Studies

33 other study(ies) available for amiodarone and uk 68798

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Hemodynamic effects of antiarrhythmic compounds: intrinsic effects and autonomic modulation. The American journal of cardiology, 1997, Oct-23, Volume: 80, Issue:8A Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Heart Conduction System; Hemodynamics; Humans; Male; Myocardial Contraction; Phenethylamines; Rats; Rats, Wistar; Sotalol; Sulfonamides	1997
[Heart failure and sudden cardiac death: pharmacological and nonpharmacological treatment possibilities from the viewpoint of the rhythmologist]. Zeitschrift fur Kardiologie, 2000, Volume: 89 Suppl 7 Topics: Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Cardiac Pacing, Artificial; Clinical Trials as Topic; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Follow-Up Studies; Heart Failure; Humans; Multicenter Studies as Topic; Phenethylamines; Potassium Channel Blockers; Randomized Controlled Trials as Topic; Risk Factors; Sulfonamides; Vasodilator Agents	2000
Differential effects of dofetilide, amiodarone, and class lc drugs on left and right atrial refractoriness and left atrial vulnerability in pigs. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:2 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function, Left; Atrial Function, Right; Flecainide; Male; Phenethylamines; Propafenone; Sulfonamides; Swine	2001
Frequency dependent prolongation of effective refractory period by a complex class III antiarrhythmic agent CPU-86017. Acta pharmacologica Sinica, 2001, Volume: 22, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Berberine; Calcium Channel Blockers; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Papillary Muscles; Phenethylamines; Piperidines; Potassium Channel Blockers; Refractory Period, Electrophysiological; Sulfonamides; Verapamil	2001
Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights into the mechanism of the superior efficacy of amiodarone. Circulation, 2003, Mar-18, Volume: 107, Issue:10 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channels, L-Type; Dogs; Electrocardiography; Electrophysiology; Flecainide; Heart Atria; Phenethylamines; Refractory Period, Electrophysiological; Sulfonamides; Tachycardia	2003
[Progress in the clinical use of anti-arrhythmic drugs (I)]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2003, Volume: 41, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Clinical Trials as Topic; Humans; Hydantoins; Imidazoles; Imidazolidines; Phenethylamines; Piperazines; Sulfonamides	2003
Introduction--roundtable on atrial fibrillation: update on mechanisms and approaches to treatment. Journal of cardiovascular electrophysiology, 2003, Volume: 14, Issue:12 Suppl Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Catheter Ablation; Humans; Palliative Care; Phenethylamines; Sulfonamides; Treatment Outcome	2003
Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs. Medical science monitor : international medical journal of experimental and clinical research, 2004, Volume: 10, Issue:7 Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Atropine; Biphenyl Compounds; Chromans; Flecainide; Heart Atria; Hydantoins; Imidazoles; Imidazolidines; Male; Phenethylamines; Piperazines; Potassium Channel Blockers; Potassium Channels; Propafenone; Propanolamines; Sotalol; Sulfonamides; Swine; Ventricular Function	2004
The influence of extracellular acidosis on the effect of IKr blockers. Journal of cardiovascular pharmacology and therapeutics, 2005, Volume: 10, Issue:1 Topics: Acidosis; Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Humans; Hydantoins; Imidazolidines; Myocardial Infarction; Oocytes; Phenethylamines; Piperazines; Potassium Channels; Potassium Channels, Voltage-Gated; Quinidine; Sulfonamides; Trans-Activators; Xenopus laevis	2005
Use of a failing rabbit heart as a model to predict torsadogenicity. Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 93, Issue:1 Topics: Amiodarone; Animals; Cardiac Output, Low; Cisapride; Dose-Response Relationship, Drug; Electrocardiography; Models, Animal; Phenethylamines; Quaternary Ammonium Compounds; Quinidine; Rabbits; Sulfonamides; Torsades de Pointes; Verapamil	2006
Effect of atrial electrical remodeling on the efficacy of antiarrhythmic drugs: comparison of amiodarone with I(Kr)- and I(to)/IKur-blockade in vivo. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:12 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Goats; Heart Conduction System; Injections, Intravenous; Male; Phenethylamines; Potassium Channel Blockers; Sulfonamides; Swine	2007
Amiodarone and atrial fibrillation. Journal of cardiovascular electrophysiology, 2007, Volume: 18, Issue:12 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Goats; Heart Conduction System; Injections, Intravenous; Male; Phenethylamines; Potassium Channel Blockers; Sulfonamides; Swine	2007
Alternatives to amiodarone: search for the Holy Grail. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2009, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzofurans; Combined Modality Therapy; Dose-Response Relationship, Drug; Dronedarone; Humans; Pacemaker, Artificial; Phenethylamines; Sulfonamides	2009
Efficacy and safety of dofetilide in the treatment of frequent ventricular tachyarrhythmias after amiodarone intolerance or failure. Journal of the American College of Cardiology, 2011, Jan-18, Volume: 57, Issue:3 Topics: Amiodarone; Cohort Studies; Female; Humans; Male; Phenethylamines; Sulfonamides; Tachycardia, Ventricular; Time Factors; Treatment Failure; Treatment Outcome	2011
Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis. Journal of cardiovascular electrophysiology, 2011, Volume: 22, Issue:10 Topics: Acidosis; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flecainide; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Potassium; Potassium Channel Blockers; Sulfonamides; Time Factors; Transfection	2011
Comparative effectiveness of antiarrhythmic drugs for rhythm control of atrial fibrillation. Journal of cardiology, 2016, Volume: 67, Issue:5 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Dronedarone; Female; Humans; Male; Patient Admission; Pennsylvania; Phenethylamines; Recurrence; Retrospective Studies; Sotalol; Stroke; Sulfonamides	2016
Antiarrhythmic effect of the Ca Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:11-12 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Synergism; Guinea Pigs; Heart; Heart Rate; Isolated Heart Preparation; Phenethylamines; Potassium Channel Blockers; Pyridines; Small-Conductance Calcium-Activated Potassium Channels; Sulfonamides; Thiazoles	2016
Frequency of Adverse Event Monitoring in Ambulatory Patients on Amiodarone or Dofetilide. Journal of pharmacy practice, 2018, Volume: 31, Issue:5 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenethylamines; Retrospective Studies; Sulfonamides	2018
Safety of rapid switching from amiodarone to dofetilide in atrial fibrillation patients with an implantable cardioverter-defibrillator. Heart rhythm, 2019, Volume: 16, Issue:7 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Defibrillators, Implantable; Female; Hospitalization; Humans; Male; Middle Aged; Phenethylamines; Retrospective Studies; Sulfonamides	2019
Different effects of amiodarone and dofetilide on the dispersion of repolarization between well-coupled ventricular and Purkinje fibers Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:1 Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Dogs; Electrocardiography; Female; Heart Ventricles; Humans; Male; Microelectrodes; Models, Animal; Phenethylamines; Purkinje Fibers; Sulfonamides; Tachycardia, Ventricular	2021
Comparative Efficacy of Dofetilide Versus Amiodarone in Patients With Atrial Fibrillation. JACC. Clinical electrophysiology, 2021, Volume: 7, Issue:5 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Phenethylamines; Stroke Volume; Sulfonamides; Ventricular Function, Left	2021