amiodarone and sirolimus

amiodarone has been researched along with sirolimus in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's6 (50.00)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Beck, WT; Schuetz, EG; Schuetz, JD1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dipchand, AI; Nalli, N; Stewart-Teixeira, L1
Glanville, AR; Hayward, CS; Keogh, AM; Macdonald, PS; Otton, J1
Choi, YJ; Lee, BH; Lee, K; Lee, KY; Oh, S; Oh, SH; Yang, MJ; Yang, YS1
Aboulhoda, BE; Ashour, H; El-Hanbuli, H; Harb, I; Mahmoud, H; Mostafa, A; Rashed, LA; Rashwan, E; Samir, M1

Reviews

1 review(s) available for amiodarone and sirolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for amiodarone and sirolimus

ArticleYear
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:2

    Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil

1996
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
    Nature chemical biology, 2008, Volume: 4, Issue:5

    Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Amiodarone-sirolimus/tacrolimus interaction in a pediatric heart transplant patient.
    Pediatric transplantation, 2006, Volume: 10, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Fatal Outcome; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Infant; Sirolimus; Tacrolimus

2006
Everolimus-associated pneumonitis in 3 heart transplant recipients.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:1

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Everolimus; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Pneumonia; Radiography, Thoracic; Sirolimus; Tomography, X-Ray Computed

2009
Activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and pulmonary toxicity in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Adenine; Administration, Inhalation; Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Autophagy; Autophagy-Related Protein 7; Bronchoalveolar Lavage Fluid; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Gene Knockdown Techniques; Humans; Lung; Macrolides; Male; Microtubule-Associated Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred F344; RNA Interference; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Transfection; Ubiquitin-Activating Enzymes

2013
Nicorandil mitigates amiodarone-induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF-β1/PI3K/Akt1-p/mTOR axis in rats.
    Clinical and experimental pharmacology & physiology, 2023, Volume: 50, Issue:1

    Topics: Amiodarone; Animals; Fibrosis; Lung; Mammals; Nicorandil; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Rats; Sirolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1

2023