amiodarone and sematilide

amiodarone has been researched along with sematilide in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Honerjäger, P; Schmidt, G1
Cui, G; Sager, P; Sen, L; Singh, BN; Uppal, P1
Follmer, C; Godfrey, R; Pruitt, C; Sager, PT; Uppal, P1
Hashimoto, K; Ishida, Y; Kugiyama, K; Satoh, Y; Sugiyama, A; Yoneyama, M; Yoshida, H1

Reviews

1 review(s) available for amiodarone and sematilide

ArticleYear
[New anti-arrhythmia agents].
    Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Phenethylamines; Procainamide; Propanolamines; Sotalol; Sulfonamides; Survival Rate; Tachycardia

1992

Trials

2 trial(s) available for amiodarone and sematilide

ArticleYear
Effects of amiodarone, sematilide, and sotalol on QT dispersion.
    The American journal of cardiology, 1994, Nov-01, Volume: 74, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Follow-Up Studies; Heart Conduction System; Humans; Male; Middle Aged; Procainamide; Retrospective Studies; Sotalol; Tachycardia, Ventricular; Time Factors

1994
The effects of beta-adrenergic stimulation on the frequency-dependent electrophysiologic actions of amiodarone and sematilide in humans.
    Circulation, 1994, Volume: 90, Issue:4

    Topics: Action Potentials; Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart; Heart Conduction System; Humans; Isoproterenol; Middle Aged; Procainamide; Prospective Studies; Reaction Time; Refractory Period, Electrophysiological; Tachycardia, Ventricular; Ventricular Function

1994

Other Studies

5 other study(ies) available for amiodarone and sematilide

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:8

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Female; Heart Block; Male; Procainamide; Torsades de Pointes

2002