amiodarone has been researched along with propylthiouracil in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (28.21) | 18.7374 |
| 1990's | 9 (23.08) | 18.2507 |
| 2000's | 9 (23.08) | 29.6817 |
| 2010's | 10 (25.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Lipski, A; Mavroudakis, N; Unger, J; van Coevorden, A | 1 |
| Unger, J; Van Reeth, O | 2 |
| Boddaert, A; Chevrier, M; Cordier, A; De Sandro, V; Melcion, C; Richert, L | 1 |
| Chailurkit, LO; Himathongkam, T; Kongsuksai, A; Rajatanavin, R; Teeravaninthorn, U | 1 |
| Brzezińska-Slebodzińska, E; Kapluk, J | 1 |
| Unger, J | 1 |
| Bianchi, C; Meruane, J; Pineda, G; Valenzuela, MA | 2 |
| Goldberger, J; Goldberger, S | 1 |
| Bernard, R; Bonnyns, M; Bourdoux, P; Demaret, B; Renard, M; Sterling, I | 1 |
| De Weweire, A; Delwiche, F; Unger, J; Unger, P | 1 |
| Chosich, N; Harper, RW; Le Grand, BA; Newnham, HH; Stockigt, JR; Topliss, DJ | 1 |
| Gheri, RG | 1 |
| Burman, KD; Wartofsky, L | 1 |
| Braverman, LE; Mordes, JP; Rajatanavin, R; Safran, M; Stoller, WA | 1 |
| Chopra, IJ; Huang, TS; Hurd, RE; Solomon, DH | 1 |
| Bakker, O; Hudig, F; Wiersinga, WM | 1 |
| de Jong, M; Docter, R; Hennemann, G; Krenning, E; Plaisier, P; Quero, C; Van der Heide, D; Van der Hoek, H; Vos, R | 1 |
| Adawi, F; Baron, E; Dickstein, G; Ish-Shalom, S; Kaplan, J; Shechner, C | 1 |
| Burikhanov, RB; Matsuzaki, S | 1 |
| Bogazzi, F; D'Ascoli, F; Di Matola, T; Fenzi, G; Martino, E; Rossi, G; Vitale, M | 1 |
| Franklyn, JA; Gammage, MD; Osman, F; Sheppard, MC | 1 |
| Acu, B; Alyan, O; Arda, K; Demirkan, D; Ozdemir, O; Soylu, M | 1 |
| Arteaga, E; Brusco, F; González, G; Soto, N | 1 |
| Brigante, G; Diazzi, C; Rochira, V; Rossi, G | 1 |
| Aarts, JM; Hermsen, SA; Jomaa, B; Kessels, MY; Peijnenburg, AA; Piersma, AH; Rietjens, IM; van den Berg, JH | 1 |
| Gershinsky, M; Gronich, N; Lavi, I; Saliba, W; Shapira, C | 1 |
1 review(s) available for amiodarone and propylthiouracil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for amiodarone and propylthiouracil
| Article | Year |
|---|---|
The effect of amiodarone on the control of hyperthyroidism by propylthiouracil.
Topics: Adult; Amiodarone; Drug Therapy, Combination; Female; Graves Disease; Hemodynamics; Humans; Middle Aged; Propylthiouracil; Thyroxine; Triiodothyronine; Weight Gain | 1990 |
37 other study(ies) available for amiodarone and propylthiouracil
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Treatment of supraventricular tachyarrhythmias associated with hyperthyroidism by radioiodine, amiodarone and propylthiouracil.
Topics: Adult; Aged; Amiodarone; Combined Modality Therapy; Female; Humans; Hyperthyroidism; Iodine; Iodine Radioisotopes; Male; Propylthiouracil; Tachycardia, Supraventricular; Thyroxine; Triiodothyronine | 1991 |
Effects of amiodarone on serum T3 and T4 concentrations in hyperthyroid patients treated with propylthiouracil.
Topics: Adult; Aged; Amiodarone; Analysis of Variance; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Iodine; Male; Middle Aged; Propylthiouracil; Thyroxine; Triiodothyronine | 1991 |
The effect of amiodarone on the control of hyperthyroidism by propylthiouracil.
Topics: Amiodarone; Drug Therapy, Combination; Humans; Hyperthyroidism; Propylthiouracil | 1991 |
Comparison of the effects of propylthiouracil, amiodarone, diphenylhydantoin, phenobarbital, and 3-methylcholanthrene on hepatic and renal T4 metabolism and thyroid gland function in rats.
Topics: Amiodarone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochromes b5; Glucuronosyltransferase; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxygenases; Phenobarbital; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Ontogenic characterization of type I and II thyroxine 5'-monodeiodinases in brown adipose tissue from fetal and newborn rabbits.
Topics: Adipose Tissue, Brown; Age Factors; Amiodarone; Animals; Animals, Newborn; Dithiothreitol; Dose-Response Relationship, Drug; Fetus; Iodide Peroxidase; Iopanoic Acid; Propylthiouracil; Rabbits; Thyroxine; Triiodothyronine | 1990 |
[Treatment of hyperthyroidism: inhibitors of T4-T3 conversion].
Topics: Adrenal Cortex Hormones; Amiodarone; Antithyroid Agents; Humans; Hyperthyroidism; Ipodate; Lithium; Methimazole; Propranolol; Propylthiouracil; Thyroxine; Triiodothyronine | 1986 |
[Efficacy of propylthiouracil in the treatment of amiodarone-induced hyperthyroidism].
Topics: Adult; Aged; Amiodarone; Female; Humans; Hyperthyroidism; Male; Middle Aged; Propylthiouracil; Thyroid Hormones | 1989 |
Iatrogenic thyroid dysfunction.
Topics: Amiodarone; Humans; Hyperthyroidism; Male; Middle Aged; Propylthiouracil; Tachycardia; Thyroid Function Tests | 1989 |
Dexamethasone treatment of amiodarone-induced thyrotoxicosis (AIT) with or without persistent administration of the drug.
Topics: Amiodarone; Dexamethasone; Humans; Male; Middle Aged; Propylthiouracil; Tachycardia; Thyrotoxicosis | 1989 |
Failure to control hyperthyroidism with a thionamide after KClO4 withdrawal in a patient with amiodarone associated thyrotoxicosis.
Topics: Amiodarone; Humans; Hyperthyroidism; Male; Middle Aged; Perchlorates; Potassium; Potassium Compounds; Propylthiouracil | 1987 |
Amiodarone-induced hyperthyroidism: assessment of the predictive value of biochemical testing and response to combined therapy using propylthiouracil and potassium perchlorate.
Topics: Adolescent; Adult; Aged; Amiodarone; Child; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Male; Middle Aged; Perchlorates; Potassium; Potassium Compounds; Predictive Value of Tests; Propylthiouracil; Sex Hormone-Binding Globulin; Thyroglobulin; Thyroid Function Tests; Thyrotropin; Thyroxine | 1988 |
[Behavior of the cardiologist when faced with amiodarone-induced hormonal changes].
Topics: Adult; Amiodarone; Female; Glucocorticoids; Humans; Hyperthyroidism; Hypothyroidism; Male; Perchlorates; Plasmapheresis; Potassium; Potassium Compounds; Propylthiouracil; Thyroid Hormones; Thyroidectomy; Thyroxine | 1988 |
[Hyper- or hypothyroidism in chronic treatment with amiodarone: a diagnostic and therapeutic dilemma].
Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Propylthiouracil; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine | 1985 |
Effects of drugs on peripheral thyroxine metabolism.
Topics: Amiodarone; Animals; Humans; Iopanoic Acid; Ipodate; Liver; Pituitary Gland; Propranolol; Propylthiouracil; Receptors, Cell Surface; Receptors, Thyroid Hormone; Steroids; Thyroxine; Triiodothyronine | 1984 |
Five patients with iodine-induced hyperthyroidism.
Topics: Adult; Amiodarone; Chlorobutanol; Coloring Agents; Coronary Artery Bypass; Drug Combinations; Female; Goiter, Nodular; Graves Disease; Humans; Hyperthyroidism; Iodine; Iodine Radioisotopes; Male; Middle Aged; Niacinamide; Postoperative Complications; Povidone-Iodine; Propylthiouracil; Radiographic Image Enhancement; Sodium Iodide; Thyroid Hormones | 1984 |
A study of cardiac effects of thyroid hormones: evidence for amelioration of the effects of thyroxine by sodium ipodate.
Topics: Amiodarone; Animals; Cytosol; Diiodothyronines; Glycerolphosphate Dehydrogenase; Heart; Ipodate; Kinetics; Male; Mitochondria, Heart; Organ Size; Ornithine Decarboxylase; Propranolol; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1984 |
Amiodarone-induced hypercholesterolemia is associated with a decrease in liver LDL receptor mRNA.
Topics: Amiodarone; Animals; Cholesterol 7-alpha-Hydroxylase; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Liver; Male; Propylthiouracil; Rats; Rats, Wistar; Receptors, LDL; RNA, Messenger; Time Factors | 1994 |
Different effects of amiodarone on transport of T4 and T3 into the perfused rat liver.
Topics: Amiodarone; Animals; Biological Transport; Culture Media; In Vitro Techniques; Iodide Peroxidase; Liver; Male; Perfusion; Propylthiouracil; Rats; Thyroxine; Triiodothyronine | 1994 |
Lithium treatment in amiodarone-induced thyrotoxicosis.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Drug Therapy, Combination; Humans; Lithium Carbonate; Propylthiouracil; Thyrotoxicosis; Time Factors; Treatment Outcome | 1997 |
Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo.
Topics: Amiodarone; Animals; Antithyroid Agents; Apoptosis; Diiodotyrosine; DNA Fragmentation; Goiter; Male; Methimazole; Potassium Iodide; Propylthiouracil; Rats; Rats, Wistar; Thyroid Gland | 2000 |
Amiodarone induces cytochrome c release and apoptosis through an iodine-independent mechanism.
Topics: Amiodarone; Annexin A5; Anti-Arrhythmia Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cell Line; Cell Survival; Cycloheximide; Cytochrome c Group; Cytosol; HeLa Cells; Humans; Iodide Peroxidase; Kinetics; Mitochondria; Propylthiouracil; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Thyroid Gland; Tumor Suppressor Protein p53 | 2000 |
Successful treatment of amiodarone-induced thyrotoxicosis.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Autoantibodies; Carbimazole; Cohort Studies; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Propylthiouracil; Retrospective Studies; Steroids; Thyrotoxicosis; Thyrotropin; Thyroxine; Treatment Outcome; Triiodothyronine | 2002 |
Differential diagnosis and clinical course of amiodarone-induced thyroid dysfunction.
Topics: Adult; Aged; Amiodarone; Antithyroid Agents; Atrial Fibrillation; Diagnosis, Differential; Female; Humans; Hypothyroidism; Male; Middle Aged; Propylthiouracil; Tachycardia, Ventricular; Thyrotoxicosis; Ultrasonography, Doppler, Color | 2003 |
Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure.
Topics: Adult; Amiodarone; Female; Humans; Hyperthyroidism; Liver Failure, Acute; Propylthiouracil; Triiodothyronine | 2004 |
Propylthiouracil-induced interstitial pneumonia in a Caucasian woman with amiodarone-induced thyrotoxicosis.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Atrial Fibrillation; Cryptogenic Organizing Pneumonia; Female; Humans; Propylthiouracil; Radiography; Thyrotoxicosis; White People | 2012 |
Developmental toxicity of thyroid-active compounds in a zebrafish embryotoxicity test.
Topics: Amiodarone; Animal Testing Alternatives; Animals; Anti-Arrhythmia Agents; Antithyroid Agents; Embryo, Nonmammalian; Embryonic Development; Hazardous Substances; Methimazole; Perchlorates; Propylthiouracil; Sodium Compounds; Thyroid Gland; Thyroid Hormones; Time Factors; Toxicity Tests; Zebrafish | 2014 |
Increased Risk of Antithyroid Drug Agranulocytosis Associated with Amiodarone-Induced Thyrotoxicosis: A Population-Based Cohort Study.
Topics: Adult; Aged; Agranulocytosis; Amiodarone; Antithyroid Agents; Female; Humans; Male; Methimazole; Middle Aged; Proportional Hazards Models; Propylthiouracil; Retrospective Studies; Risk; Thyrotoxicosis | 2019 |