amiodarone has been researched along with propranolol in 136 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (41.91) | 18.7374 |
| 1990's | 29 (21.32) | 18.2507 |
| 2000's | 18 (13.24) | 29.6817 |
| 2010's | 30 (22.06) | 24.3611 |
| 2020's | 2 (1.47) | 2.80 |
| Authors | Studies |
|---|---|
| Herbette, LG; Mason, RP; Rhodes, DG | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Pajeva, IK; Wiese, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Miao, GX; Wang, YD; Yan, ZW; Zhang, LY | 1 |
| Bauthier, JA; Charlier, RH; Richard, JC | 1 |
| Curry, PV; Krikler, DM; Rowland, E | 1 |
| Beaughard, M; Cosnier, D; Labrid, C; Piris, P | 1 |
| Vaughan-Williams, EM | 1 |
| Attuel, P; Coumel, P; Leclercq, JF; Milosevic, D | 1 |
| Benaim, R; Chiche, P; Derrida, JP; Haiat, R; Ollagnier, J | 1 |
| Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA | 1 |
| Chapelle, M; Naouri, R; Wolff, F | 1 |
| Goupil, N; Lenfant, J | 1 |
| Broekhuysen, J; Polster, P | 1 |
| Bourdinière, J; Lé Clech, G; Le Gall, F; Massart, C; Nicol, M | 1 |
| Aussel, C; Pelassy, C | 1 |
| Fomina, IG; Iankin, VV | 1 |
| Gorgaslidze, AG; Karaush, AP; Smetnev, AS | 1 |
| Antonenko, YN; Kinnally, KW; Perini, S; Tedeschi, H | 1 |
| Antonenko, YN; Kinnally, KW; Tedeschi, H | 1 |
| Louchahi, M; Nicolas, P; Perret, G; Uzzan, B; Vassy, R; Yin, YL | 1 |
| Cabezuelo Huerta, G; Frontera Izquierdo, P | 1 |
| Mazur, NA; Shestakova, NV | 1 |
| Kurbanov, RD | 1 |
| Nicolas, P; Perret, G; Pré, J; Vassy, R | 1 |
| Bourdarias, JP; Delorme, G; Dubourg, O; Legendre, M; Pelissier, C; Varin, J; Weiss, P | 1 |
| Cifarelli, A; Garcia, JM; Garson, A; Herre, J; Vetter, VL; Villain, E | 1 |
| Bandyopadhyay, S; Klaunig, JE; Somani, P | 1 |
| Unger, J | 1 |
| Antiu'fev, VF; Arkhipov, MV | 1 |
| Beavis, AD | 1 |
| Blondeau, M; Brunet, M; Fedorowsky, A; Fournier, C; Gensous, D; Kindermans, M; Tournadre, P | 1 |
| Brotelle, R; Chatelain, P; Laruel, R; Vic, P | 1 |
| Kleinebenne, A; McKenna, WJ | 1 |
| Bah, M; Blondeau, M; Boujon, B; Brunet, M; Fournier, C; Giudicelli, JF; Kindermans, M; Tournadre, P | 1 |
| Condé, D; Hody, B; Leclech, G; Massart, C; Nicol, M | 1 |
| Morganroth, J; Nestico, PF | 2 |
| Anticoli Borza, S; Bargellini, F; Carolis, S; Casciani, M; Podestà, M | 1 |
| Weissel, M | 1 |
| Agmon, J; Bassevich, R; Klainman, E; Rechavia, E; Sagie, A; Sclarovsky, S | 1 |
| Chester, DW; Herbette, LG; Katz, AM; Trumbore, M | 1 |
| Foz, M; Lucas, A; Salinas, I; Sanmartí, A | 1 |
| Agmon, J; Caspi, A; Kusniec, J; Lewin, RF; Sclarovsky, S; Strasberg, B | 1 |
| Coudert, B; Dwyer, TM; Joshi, UM; Kodavanti, PR; Mehendale, HM | 1 |
| Schwartz, PJ; Vanoli, E | 1 |
| Abalovich, MS; Aszenmil, G; Guitelman, A; Gutiérrez, S | 1 |
| Stewart, PA; Wladimiroff, JW | 1 |
| Bekhbudova, DA; Bochkareva, EV; Kokurina, EV; Ostrovskaia, TP; Urumbaev, RK | 1 |
| Furkalo, NK; Ivashchenko, TI; Romanenko, AI | 1 |
| Buchanan, D; Crawford, F; Gillette, PC; Zinner, A | 1 |
| Chowdry, IH; Gomes, JA; Hariman, RJ; Kang, PS | 1 |
| Schwartz, PJ; Vanoli, E; Zaza, A; Zuanetti, G | 1 |
| Gang, ES; Hamer, A; Mandel, WJ; Oseran, DS; Peter, T; Rosenthal, ME | 1 |
| Adinolfi, L; Bonaduce, D; Chiariello, M; Dote, I; Golia, B; Masullo, LA | 1 |
| Bertoletti, JC; Daudt, NS; Firpo, CM; Guillermo-Cal, L; Moura, MR; Vitola, D; Wagner, EM; Zielinsky, P | 1 |
| De Thomatis, M | 1 |
| Burman, KD; Wartofsky, L | 1 |
| Braverman, LE; Rajatanavin, R | 1 |
| Hess, DS; Scheinman, MM | 1 |
| Rosen, MR; Wit, AL | 1 |
| Degtiareva, LV; Gichka, SG; Grigor'eva, NN; Stepaniuk, GI | 1 |
| Goodwin, JF; Oakley, CM | 1 |
| Feld, GK; Nademanee, K; Singh, BN; Stevenson, W; Weiss, J | 1 |
| Chopra, IJ; Huang, TS; Hurd, RE; Solomon, DH | 1 |
| Cao, J | 1 |
| Golitsyn, SP; Grosu, AA; Smetnev, AS; Sokolov, SF | 1 |
| Cho, YW; Kuemmerle, HP; Singh, BN | 1 |
| Botvinick, EH; Hess, D; Morady, F; Scheinman, MM; Shen, EN; Sung, RJ | 1 |
| Flinn, CJ; Gelband, H; Pickoff, AS; Singh, S; Wolff, GS | 1 |
| Goodwin, JF; McKenna, WJ | 1 |
| Araujo, LI; Crosatto, JR; Dyszel, E; Girotti, LA; Kaski, JC; Messuti, H; Rivas, CA; Rosenbaum, MB; Vetulli, HD | 1 |
| Bernard, B; Docter, R; Hennemann, G; Krenning, EP; Visser, T | 1 |
| Camous, JP; Crenesse, D; Guiran, JB; Lapalus, P; Varenne, A | 1 |
| Chiavarelli, V; Milazzotto, F; Vajola, SF | 1 |
| Abdullaev, TA; Asriiants, LS; Avezov, DK; Azimova, NA; Faĭzullaev, BP; Kiakbaev, GK; Kurbanov, RD; Zakirov, NU | 1 |
| Galenko-Iaroshevskiĭ, PA; Kostin, IaV; Lemkina, SM; Sergeev, PV | 1 |
| al-Achi, A; Greenwood, R; Jendrasiak, GL; Nemecz, G | 1 |
| Abu-Much, Z; Rafael, C; Rozenfeld, V; Schoham, H; Schwartz, J | 1 |
| Patterson, FK; Wigler, PW | 1 |
| DiDio, LJ; Lopes, AC; Mora, O; Sasso, WS | 1 |
| Bartashevich, VV; Galenko-Iaroshevskiĭ, PA; Galygo, DS; Khankoeva, AI; Melkumova, ER; Turovaia, AIu; Uvarov, AV | 1 |
| Bhuripanyo, K; Chaowakul, V; Kuasirikul, S; Likittanasombat, K; Malasit, P; Nademanee, K; Nimmannit, S; Tansupasawadikul, S; Tatsanavivat, P; Tunsanga, K; Veerakul, G | 1 |
| Jacobsen, EA; Mortensen, E; Pedersen, HK; Refsum, H | 1 |
| Chang, MS; Chen, SA; Ding, YA; Feng, AN; Kuo, BI; Lee, SH; Tai, CT; Yu, WC | 1 |
| Bartashevich, VV; Boldin, VB; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI; Popov, PB; Sirotenko, DV; Uvarov, AV | 1 |
| Bowers, PN; Fields, J; Nehgme, R; Rosenfeld, LE; Schwartz, D | 1 |
| Bariciak, MD; Nichols, BD | 1 |
| Craelius, W; Geller, HM; Green, WL; Huang, CJ | 1 |
| Landwojtowicz, E; Seelig, A | 1 |
| Suttorp, MJ; Tahapary, GJ | 1 |
| Greenberg, MD; Katz, NM; Kilborn, MJ; Solomon, AJ | 1 |
| Bali, S; Casey, F; Doherty, G | 1 |
| Chi, CS; Fu, YC; Jan, SL; Wang, JD | 1 |
| Anastasiou-Nana, MI; Kanakakis, J; Rokas, S; Tsagalou, EP | 1 |
| Arakaki, T; Isomoto, S; Kawakami, A; Ono, K; Yamashita, S; Yano, K | 1 |
| Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C | 1 |
| Ghazinoor, M; Jannati, M; Kojuri, J; Mahmoodi, Y; Shafa, M; Sharifkazemi, MB | 1 |
| Abello, M; Benjamín, MN; Infante, J; Moltedo, JM; Olmedo, J | 1 |
| Goodman, IS; Lu, CJ | 1 |
| Ding, AW; Duan, JA; Lü, GH; Lu, WJ; Ma, HY; You, FQ; Zhou, J | 1 |
| Akin, A; Alehan, D; Aykan, HH; Karagöz, T; Özer, S; Özkutlu, S | 1 |
| Bollmann, A; Hilbert, S; Hindricks, G; John, S; Kosiuk, J | 1 |
| Geurts, P; Jeanray, N; Marée, R; Muller, M; Pruvot, B; Stern, O; Wehenkel, L | 1 |
| Álvarez-Fernández, L; Brañas-Fernández, FM; Cortés-Laíño, JA; da Silva-Franca, CF; Nogueira-Fernández, V; Pego-Reigosa, R; Ramos-Rúa, L | 1 |
| Alhumayyd, MS; Almotrefi, AA; Bukhari, IA | 1 |
| Akdeniz, C; Ergül, Y; Özyılmaz, İ; Saygı, M; Tola, HT; Tuzcu, V | 1 |
| Baghazza, S; Bencherif, R; Chaabna, K; Djezzar, S; Guehimeche, R; Mallem, D; Rouabhia, S; Sadelaoud, M; Sadouki, H | 1 |
| Hasanzadeh, M; Niaei, N; Shadjou, N | 1 |
| Chatfield, KC; Czosek, RJ; Epstein, MR; Ganesh, J; Gillespie, MJ; Goldenberg, P; Gripp, KW; Kalish, JM; Levin, MD; Lin, AE; Myers, A; Saitta, SC; Smith, R; Ware, SM; Wenger, TL; Zackai, EH | 1 |
| Cioppa, ND; Ciriello, GD; Colonna, D; Correra, A; Palladino, MT; Papaccioli, G; Romeo, E; Russo, MG; Sarubbi, B | 1 |
15 review(s) available for amiodarone and propranolol
| Article | Year |
|---|---|
Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interaction with biological membranes.
Topics: Cell Membrane; Chemical Phenomena; Chemistry, Physical; Kinetics; Lipid Bilayers; Membrane Lipids; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship | 1991 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Supraventricular paroxysmal tachycardia without congenital heart disease: clinical, therapeutic aspects and course in 65 children].
Topics: Amiodarone; Child; Child, Preschool; Digoxin; Female; Humans; Male; Propranolol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular | 1991 |
[Mechanisms of interactions of anti-arrhythmia agents during their combined use].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Potassium; Procainamide; Propranolol; Quinidine; Verapamil | 1991 |
[Comparative characteristics of arrhythmogenic effects of anti-arrhythmia agents].
Topics: Aconitine; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Humans; Moricizine; Phenothiazines; Procainamide; Propranolol | 1991 |
Evolving concepts in the management of congenital junctional ectopic tachycardia. A multicenter study.
Topics: Amiodarone; Bundle of His; Digoxin; Drug Therapy, Combination; Echocardiography; Humans; Infant; Multicenter Studies as Topic; Pacemaker, Artificial; Propranolol; Tachycardia, Ectopic Junctional; Tachycardia, Supraventricular | 1990 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Antiarrhythmic agents for chronic ventricular arrhythmias.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide | 1987 |
[Modification of peripheral thyroid hormone metabolism by drugs].
Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1988 |
Euthyroid hyperthyroxinemia.
Topics: Amiodarone; Autoantibodies; Dextroamphetamine; Heparin; Humans; Propranolol; Serum Albumin; Thyroglobulin; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine | 1983 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil | 1983 |
Electropharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil | 1983 |
The natural history of hypertrophic cardiomyopathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Death, Sudden; Humans; Nifedipine; Prognosis; Propranolol; Verapamil | 1981 |
Cataracts in systemic diseases and syndromes.
Topics: Amiodarone; Cataract; Cataract Extraction; Diabetes Complications; Diabetic Retinopathy; Female; Humans; Lens, Crystalline; Lovastatin; Male; Neurofibromatosis 2; Propranolol; Syndrome | 1995 |
[Paroxysmal atrial fibrillation within the context of cluster headaches].
Topics: Amiodarone; Anti-Inflammatory Agents, Non-Steroidal; Atrial Fibrillation; Autonomic Nervous System Diseases; Cluster Headache; Flecainide; Humans; Hypothalamus, Posterior; Male; Middle Aged; Models, Neurological; Oxygen Inhalation Therapy; Propranolol; Trigeminal Nerve | 2015 |
10 trial(s) available for amiodarone and propranolol
| Article | Year |
|---|---|
[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
Topics: Adult; Aged; Aged, 80 and over; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Pre-Excitation Syndromes; Procainamide; Propranolol; Quinidine; Time Factors; Verapamil | 1992 |
[Anti-angina effect of amiodarone versus delayed-action propranolol. A double-blind randomized study].
Topics: Adult; Aged; Amiodarone; Angina Pectoris; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Humans; Male; Middle Aged; Propranolol; Time Factors | 1990 |
Evolving concepts in the management of congenital junctional ectopic tachycardia. A multicenter study.
Topics: Amiodarone; Bundle of His; Digoxin; Drug Therapy, Combination; Echocardiography; Humans; Infant; Multicenter Studies as Topic; Pacemaker, Artificial; Propranolol; Tachycardia, Ectopic Junctional; Tachycardia, Supraventricular | 1990 |
[Comparative efficacy of amiodarone and propranolol on ventricular arrhythmia in the post-infarction period].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Propranolol; Prospective Studies; Random Allocation | 1989 |
Comparison of the efficacy of propranolol and amiodarone in suppressing ventricular arrhythmias following myocardial infarction.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Propranolol; Prospective Studies; Randomized Controlled Trials as Topic | 1989 |
[Thrombocyte aggregation in patients with cardiac arrhythmias and effect of anti-arrhythmia agents].
Topics: Aconitine; Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Heart Rate; Humans; Male; Middle Aged; Phenothiazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Propranolol; Tachycardia, Supraventricular | 1993 |
Tachycardia-induced change of atrial refractory period in humans: rate dependency and effects of antiarrhythmic drugs.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Electrophysiology; Female; Humans; Male; Middle Aged; Pacemaker, Artificial; Procainamide; Propafenone; Propranolol; Sotalol; Tachycardia, Supraventricular; Verapamil | 1998 |
Amiodarone versus a beta-blocker to prevent atrial fibrillation after cardiovascular surgery.
Topics: Aged; Amiodarone; Atrial Fibrillation; Coronary Artery Bypass; Coronary Disease; Heart Valves; Humans; Male; Middle Aged; Pilot Projects; Postoperative Complications; Propranolol | 2001 |
Ability of amiodarone and propranolol alone or in combination to prevent post-coronary bypass atrial fibrillation.
Topics: Adult; Aged; Amiodarone; Atrial Fibrillation; Coronary Artery Bypass; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Postoperative Complications; Propranolol | 2009 |
The efficacy of amiodarone-propranolol combination for the management of childhood arrhythmias.
Topics: Adolescent; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Male; Propranolol; Treatment Outcome | 2013 |
112 other study(ies) available for amiodarone and propranolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
Topics: Adenosine Triphosphatases; Algorithms; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Rhodamine 123; Stereoisomerism; Verapamil; Vinblastine | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors.
Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Glycogen Phosphorylase; Hep G2 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Indoles; Mice; Molecular Structure; Rats; Structure-Activity Relationship | 2020 |
Amiodarone-like haemodynamic and non-competitive antiadrenergic properties of a benzoyl-indolizine.
Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Coronary Circulation; Dogs; Female; Glucagon; Heart Rate; Hemodynamics; Indolizines; Male; Propranolol; Propylamines; Sympatholytics | 1977 |
Dual-demand pacing for refractory atrioventricular re-entry tachycardia.
Topics: Adult; Amiodarone; Electrocardiography; Female; Follow-Up Studies; Heart Conduction System; Heart Ventricles; Humans; Male; Middle Aged; Pacemaker, Artificial; Propranolol; Sick Sinus Syndrome; Sinus of Valsalva; Tachycardia, Paroxysmal; Time Factors; Verapamil; Wolff-Parkinson-White Syndrome | 1979 |
Activity of bepridil and other anti-anginals on cardiovascular modifications engendered by conditioned anxiety in the dog.
Topics: Amines; Amiodarone; Angina Pectoris; Animals; Anxiety; Behavior, Animal; Benzylamines; Conditioning, Operant; Dipyridamole; Dogs; Female; Hemodynamics; Humans; Male; Nitroglycerin; Pentaerythritol Tetranitrate; Perhexiline; Propranolol; Pyrrolidines | 1978 |
[Research on a rational basis for the origin and treatment of arrhythmia].
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Heart; Humans; Hyperthyroidism; Potassium; Propranolol; Quinidine; Rabbits; Refractory Period, Electrophysiological; Sodium; Verapamil | 1977 |
[Quantitative evaluation of the efficacy of anti-arrhythmia agents in chronic ventricular arrhythmia].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Computers; Electrocardiography; Heart Ventricles; Humans; Placebos; Propranolol; Quinidine | 1979 |
[Amiodarone and propanolol: a dangerous combination?].
Topics: Amiodarone; Benzofurans; Drug Therapy, Combination; Heart Arrest; Humans; Propranolol; Ventricular Fibrillation | 1979 |
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1978 |
[Hyperthyroidism caused by amiodarone. Apropos of 4 clinical cases].
Topics: Adult; Amiodarone; Angina Pectoris; Arrhythmias, Cardiac; Benzofurans; Electrocardiography; Female; Humans; Hyperthyroidism; Male; Middle Aged; Pindolol; Propranolol | 1976 |
The effects of amiodarone on the sinus node activity of the rabbit heart.
Topics: Action Potentials; Amiodarone; Animals; Benzofurans; Drug Interactions; Epinephrine; Female; Heart Rate; In Vitro Techniques; Male; Microelectrodes; Norepinephrine; Propranolol; Rabbits; Sinoatrial Node | 1976 |
The adrenergic antagonism of amiodarone.
Topics: Amiodarone; Animals; Aorta, Thoracic; Atrial Function; Benzofurans; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Rate; Isoproterenol; Male; Norepinephrine; Propranolol; Rabbits; Receptors, Adrenergic; Stimulation, Chemical | 1976 |
[Use of cultures of human thyroid cells in physiopathology and pharmacotoxicology].
Topics: Amiodarone; Anesthetics; Animals; Cells, Cultured; Humans; Pharmacology, Clinical; Propranolol; Thyroglobulin; Thyroid Gland; Thyroxine; Toxicology; Triiodothyronine | 1992 |
Effects of antiarrhythmic drugs on phospholipid metabolism in Jurkat T cells. The potassium channel blocker, clofilium, specifically increases phosphatidylserine synthesis.
Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Carboxy-Lyases; Choline; Decarboxylation; Dose-Response Relationship, Drug; Ethanolamine; Ethanolamines; Humans; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Propranolol; Quaternary Ammonium Compounds; T-Lymphocytes | 1992 |
[Effectiveness of single intravenous administration of cordarone, ethacizine and obsidan in ventricular extrasystole in patients with chronic alcoholism during withdrawal].
Topics: Adult; Alcoholism; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Ethanol; Humans; Injections, Intravenous; Male; Middle Aged; Phenothiazines; Propranolol; Substance Withdrawal Syndrome | 1991 |
Selective effect of inhibitors on inner mitochondrial membrane channels.
Topics: Amiodarone; Animals; Electric Conductivity; Intracellular Membranes; Ion Channels; Membrane Potentials; Mitochondria, Liver; Propranolol; Quinine; Rats; Rats, Inbred Strains | 1991 |
Identification of anion and cation pathways in the inner mitochondrial membrane by patch clamping of mouse liver mitoplasts.
Topics: Amiodarone; Animals; Anions; Cations; Electric Conductivity; Hydrogen-Ion Concentration; Intracellular Membranes; Ion Channels; Magnesium; Mice; Mitochondria, Liver; Potassium Chloride; Propranolol; Quinine | 1991 |
In vivo effects of macrolides on thyroid hormone serum levels and on hepatic type 1 5'-deiodinase in rat. A comparative study with amiodarone, phenobarbital and propranolol.
Topics: Amiodarone; Animals; Anti-Bacterial Agents; Body Weight; Iodide Peroxidase; Liver; Macrolides; Male; Phenobarbital; Propranolol; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyronines | 1991 |
Effect of a short term oral treatment by phenobarbital propranolol and amiodarone in rat on serum levels of fluorescent lipid-peroxidation products.
Topics: Amiodarone; Animals; Fluorescence; Lipid Peroxidation; Male; Phenobarbital; Propranolol; Rats; Rats, Inbred Strains | 1991 |
Cytotoxic interactions of cardioactive cationic amphiphilic compounds in primary rat hepatocytes in culture.
Topics: Amiodarone; Animals; Atenolol; Biomarkers; Cardiotonic Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Liver; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Procainamide; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Verapamil | 1990 |
[Treatment of hyperthyroidism: inhibitors of T4-T3 conversion].
Topics: Adrenal Cortex Hormones; Amiodarone; Antithyroid Agents; Humans; Hyperthyroidism; Ipodate; Lithium; Methimazole; Propranolol; Propylthiouracil; Thyroxine; Triiodothyronine | 1986 |
[Anti-arrhythmic activity of atropine, ritmilen, obsidan and cordarone in patients with ventricular allorhythmia].
Topics: Administration, Oral; Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Atropine; Cardiac Complexes, Premature; Disopyramide; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Propranolol | 1989 |
On the inhibition of the mitochondrial inner membrane anion uniporter by cationic amphiphiles and other drugs.
Topics: Algorithms; Amiodarone; Amitriptyline; Animals; Anion Transport Proteins; Benzodiazepinones; Calcimycin; Carrier Proteins; Hydrogen-Ion Concentration; Imipramine; Intracellular Membranes; Mitochondria; Propranolol; Quinine | 1989 |
Differential effects of amiodarone and propranolol on lipid dynamics and enzymatic activities in cardiac sarcolemmal membranes.
Topics: 4-Nitrophenylphosphatase; 5'-Nucleotidase; Adenosine Triphosphatases; Adenylyl Cyclases; Amiodarone; Animals; In Vitro Techniques; Male; Membrane Lipids; Myocardium; Nucleotidases; Pindolol; Propranolol; Rats; Rats, Inbred Strains; Sarcolemma | 1989 |
[Arrhythmias in hypertrophic cardiomyopathy. Significance and therapeutic consequences].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Cardiomyopathy, Hypertrophic; Death, Sudden; Drug Therapy, Combination; Electrocardiography; Heart Ventricles; Humans; Middle Aged; Propranolol; Risk; Tachycardia; Verapamil | 1985 |
Effect of amiodarone and propranolol on the functional properties of human thyroid follicles cultured in collagen gel.
Topics: Amiodarone; Cells, Cultured; Collagen; Culture Media; Humans; Propranolol; Thyroid Gland | 1989 |
[Wolff-Parkinson-White syndrome and anesthesia].
Topics: Adult; Amiodarone; Anesthesia, General; Female; Flecainide; Humans; Propranolol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Wolff-Parkinson-White Syndrome | 1987 |
Unstable angina with tachycardia: clinical and therapeutic implications.
Topics: Aged; Amiodarone; Angina Pectoris; Angina, Unstable; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Monitoring, Physiologic; Propranolol; Prospective Studies; Tachycardia; Verapamil | 1988 |
Possible molecular basis for the pharmacokinetics and pharmacodynamics of three membrane-active drugs: propranolol, nimodipine and amiodarone.
Topics: Amiodarone; Animals; Kinetics; Lipid Bilayers; Membrane Lipids; Molecular Conformation; Neutrons; Nimodipine; Propranolol; Sarcolemma; Sarcoplasmic Reticulum; Spectrum Analysis; X-Ray Diffraction | 1988 |
[Amiodarone-induced hyperthyroidism resistant to treatment with thiol derivatives].
Topics: Amiodarone; Carbimazole; Drug Resistance; Humans; Hyperthyroidism; Male; Middle Aged; Propranolol; Time Factors | 1988 |
Ventricular fibrillation in a patient with 'silent' mitral valve prolapse.
Topics: Adult; Amiodarone; Death, Sudden; Drug Therapy, Combination; Electrophysiology; Follow-Up Studies; Heart Arrest; Humans; Male; Mitral Valve Prolapse; Propranolol; Quinidine; Ventricular Fibrillation | 1988 |
Types of interaction of amphiphilic drugs with phospholipid vesicles.
Topics: Amiodarone; Anilino Naphthalenesulfonates; Binding Sites; Chloramphenicol; Chloroquine; Chlorpromazine; Diphenylhexatriene; Imipramine; Lipidoses; Lung Diseases; Membrane Lipids; Phospholipids; Promethazine; Propranolol; Surface-Active Agents; Trimipramine | 1988 |
An experimental approach to the choice of antiarrhythmic therapy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil | 1986 |
[Hyper and hypothyroidism induced by amiodarone].
Topics: Adult; Amiodarone; Female; Humans; Hyperthyroidism; Hypothyroidism; Imidazoles; Male; Middle Aged; Propranolol; Thyroid Diseases; Thyroid Function Tests; Thyroid Hormones | 1986 |
Treatment of fetal cardiac arrhythmias.
Topics: Amiodarone; Arrhythmia, Sinus; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; Diagnosis, Differential; Digoxin; Drug Therapy, Combination; Echocardiography; Edema, Cardiac; Female; Fetal Diseases; Fetal Growth Retardation; Fetal Heart; Gestational Age; Heart Rate; Humans; Karyotyping; Lung; Maternal-Fetal Exchange; Pregnancy; Procainamide; Prognosis; Propranolol; Quinidine; Ultrasonography; Vena Cava, Superior; Verapamil | 1985 |
[Characteristics of patients with ischemic heart disease under dispensary observation in a regional polyclinic and the evaluation of anti-angina therapy conducted under dispensary conditions].
Topics: Adult; Ambulatory Care; Amiodarone; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Follow-Up Studies; Humans; Isosorbide Dinitrate; Male; Nifedipine; Nitroglycerin; Propranolol; Time Factors; Vasodilator Agents; Verapamil | 1985 |
[Relation between therapeutic efficacy of antianginal preparations in patients with ischemic heart disease and their effect on the rheologic properties of blood].
Topics: Adult; Amiodarone; Benzofurans; Blood Coagulation; Blood Viscosity; Coronary Disease; Erythrocyte Aggregation; Humans; Isosorbide Dinitrate; Male; Middle Aged; Molsidomine; Nitroglycerin; Oxadiazoles; Platelet Adhesiveness; Platelet Aggregation; Propranolol; Sydnones; Vasodilator Agents | 1985 |
Ventricular tachydysrhythmias in near-miss sudden infant death syndrome.
Topics: Amiodarone; Heart Ventricles; Humans; Infant, Newborn; Infusions, Parenteral; Male; Procainamide; Propranolol; Quinidine; Recurrence; Sudden Infant Death; Tachycardia | 1986 |
Sustained symptomatic sinus node reentrant tachycardia: incidence, clinical significance, electrophysiologic observations and the effects of antiarrhythmic agents.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Electrophysiology; Humans; Male; Middle Aged; Ouabain; Propranolol; Sinoatrial Node; Tachycardia; Tachycardia, Paroxysmal; Time Factors; Verapamil | 1985 |
The effect of antiarrhythmic drugs on life-threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Disease Models, Animal; Electrocardiography; Hemodynamics; Lidocaine; Mexiletine; Prazosin; Propranolol; Stellate Ganglion | 1985 |
The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias.
Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Electrophysiology; Female; Heart Arrest; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Mitral Valve Prolapse; Procainamide; Propafenone; Propiophenones; Propranolol; Risk | 1985 |
[Ventricular tachycardia].
Topics: Amiodarone; Aprindine; Digitalis Glycosides; Electrocardiography; Heart Aneurysm; Heart Ventricles; Humans; Mexiletine; Pacemaker, Artificial; Propranolol; Quinidine; Risk; Tachycardia; Tachycardia, Paroxysmal | 1985 |
[Primary arrhythmias in pediatrics. Study of 104 patients and review of the literature].
Topics: Adolescent; Amiodarone; Arrhythmias, Cardiac; Child; Child, Preschool; Digoxin; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Prognosis; Propranolol | 1985 |
[Medical treatment of disturbances of the heart rhythm].
Topics: Ajmaline; Amiodarone; Arrhythmias, Cardiac; Digoxin; Disopyramide; Humans; Procainamide; Propranolol | 1973 |
Effects of drugs on peripheral thyroxine metabolism.
Topics: Amiodarone; Animals; Humans; Iopanoic Acid; Ipodate; Liver; Pituitary Gland; Propranolol; Propylthiouracil; Receptors, Cell Surface; Receptors, Thyroid Hormone; Steroids; Thyroxine; Triiodothyronine | 1984 |
[Morphological criteria of the effectiveness of using kordaron and obzidan in experimental myocardial ischemia].
Topics: Amiodarone; Animals; Benzofurans; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Histocytochemistry; Myocardial Infarction; Myocardium; Propranolol; Rats; Time Factors | 1984 |
Medical and surgical treatment of hypertrophic cardiomyopathy.
Topics: Adolescent; Adult; Aged; Amiodarone; Cardiomyopathy, Hypertrophic; Child; Electric Countershock; Female; Heart Septum; Humans; Male; Middle Aged; Myocardial Contraction; Propranolol; Verapamil | 1983 |
Electrophysiologic basis for the suppression by amiodarone of orthodromic supraventricular tachycardias complicating pre-excitation syndromes.
Topics: Adult; Aged; Amiodarone; Benzofurans; Digoxin; Electrocardiography; Heart Conduction System; Humans; Male; Middle Aged; Propranolol; Tachycardia; Wolff-Parkinson-White Syndrome | 1984 |
A study of cardiac effects of thyroid hormones: evidence for amelioration of the effects of thyroxine by sodium ipodate.
Topics: Amiodarone; Animals; Cytosol; Diiodothyronines; Glycerolphosphate Dehydrogenase; Heart; Ipodate; Kinetics; Male; Mitochondria, Heart; Organ Size; Ornithine Decarboxylase; Propranolol; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1984 |
[Effect of amiodarone treatment on the myocardial infart size in experimental dogs].
Topics: Amiodarone; Animals; Benzofurans; Dogs; Electrocardiography; Female; Male; Myocardial Infarction; Propranolol | 1984 |
[Method of evaluating antiarrhythmic therapy in patients with paroxysms of supraventricular tachycardia].
Topics: Adolescent; Adult; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Evaluation; Electric Stimulation; Female; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal; Verapamil | 1984 |
Clinical pharmacology of antiarrhythmic drugs: a review and overview, part II.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Propranolol; Tocainide | 1981 |
Electrophysiologic mechanism of exercise-induced sustained ventricular tachycardia.
Topics: Adolescent; Adult; Aged; Amiodarone; Cardiomyopathies; Catecholamines; Coronary Disease; Electrophysiology; Female; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Procainamide; Propranolol; Tachycardia; Time Factors | 1983 |
Use of amiodarone in the therapy of primary ventricular arrhythmias in children.
Topics: Adolescent; Age Factors; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Corneal Diseases; Drug Therapy, Combination; Female; Heart Ventricles; Humans; Male; Prognosis; Propranolol; Quinidine; Retrospective Studies; Tachycardia | 1983 |
The hyperventilation test as a method for developing successful therapy in Prinzmetal's angina.
Topics: Adult; Amiodarone; Angina Pectoris, Variant; Coronary Vasospasm; Diagnosis, Differential; Electrocardiography; Female; Follow-Up Studies; Humans; Hyperventilation; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Phentolamine; Propranolol; Verapamil | 1982 |
Decreased transport of thyroxine (T4), 3,3',5-triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs.
Topics: Adenosine Triphosphate; Amiodarone; Animals; Biological Transport, Active; Cells, Cultured; Colchicine; Cytochalasin B; Liver; Propranolol; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse; Vinblastine | 1982 |
Effects in conscious dogs of ajmaline, propranolol, amiodarone and verapamil on right ventricular anodal strength-interval curves.
Topics: Ajmaline; Amiodarone; Animals; Anti-Arrhythmia Agents; Dogs; Myocardial Contraction; Propranolol; Verapamil | 1981 |
[Pharmacological therapy and prevention of recurrent ventricular tachycardia].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Bunaftine; Disopyramide; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia | 1981 |
[A comparative study of the pharmacologic effects of combined use of strophanthin with certain antiadrenergic substances].
Topics: Adrenergic Antagonists; Amiodarone; Animals; Blood Circulation; Cardiotonic Agents; Drug Interactions; Heart Atria; In Vitro Techniques; Propranolol; Rana ridibunda; Rats; Rats, Wistar; Strophanthins; Tropanes | 1995 |
A possible nonspecific site of action of amiodarone on newborn rat heart cell in culture.
Topics: Amiodarone; Animals; Animals, Newborn; Cell Division; Cells, Cultured; Cholera Toxin; Cyclic AMP; Drug Carriers; Drug Combinations; Heart; Liposomes; Myocardium; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic, beta | 1995 |
Change of the degree of septal hypertrophy in hypertrophic obstructive cardiomyopathy under procainamide treatment. A case report.
Topics: Aged; Aged, 80 and over; Amiodarone; Bradycardia; Cardiomyopathy, Hypertrophic; Contraindications; Electrocardiography; Female; Follow-Up Studies; Heart Septum; Humans; Procainamide; Propranolol; Ultrasonography | 1995 |
Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Drug Resistance; Humans; Leukemia; Membrane Glycoproteins; Propranolol; Propylamines; Quinidine; Quinine; Rhodamine 123; Rhodamines; Stereoisomerism; Tumor Cells, Cultured | 1994 |
Propranolol-like action of amiodarone. An electronmicroscopic study in rats under cold stress.
Topics: Amiodarone; Animals; Cold Temperature; Heart; Heart Atria; Microscopy, Electron; Myocardium; Oxygen Consumption; Propranolol; Rats; Rats, Wistar; Stress, Physiological | 1997 |
[Comparative evaluation of the effect of dimebon, obzidan, finoptin, and cordarone on the functional state of the ischemic focus and the size of necrosis zone during experimental myocardial infarction].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cats; Histamine H1 Antagonists; Indoles; Myocardial Infarction; Myocardial Ischemia; Myocardium; Necrosis; Propranolol; Verapamil | 1996 |
Arrhythmogenic marker for the sudden unexplained death syndrome in Thai men.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Asia, Southeastern; Bundle-Branch Block; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardiography; Electrophysiology; Heart Conduction System; Humans; Incidence; Male; Potassium; Prevalence; Propranolol; Prospective Studies; Risk Factors; Ventricular Fibrillation; Ventricular Function, Left | 1997 |
Contrast-medium-induced ventricular fibrillation: arrhythmogenic mechanisms and the role of antiarrhythmic drugs in dogs.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Catheterization; Contrast Media; Coronary Angiography; Coronary Vessels; Dogs; Heart Conduction System; Injections, Intra-Arterial; Iohexol; Lidocaine; Premedication; Propanolamines; Propranolol; Ventricular Fibrillation; Verapamil | 1995 |
[Correction of the cardiotoxic effect of the anti-arrhythmia agents with befol, sufan, and their combination].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzamides; Benzimidazoles; Cardiotonic Agents; Dibenzazepines; Drug Antagonism; Electrocardiography; Lidocaine; Male; Morpholines; Procainamide; Propranolol; Rats; Rats, Wistar; Succinates; Tryptophan; Verapamil | 1998 |
Amiodarone induced pulmonary fibrosis in infancy.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography, Ambulatory; Follow-Up Studies; Humans; Infant, Newborn; Male; Propranolol; Pulmonary Fibrosis; Radiography, Thoracic; Tachycardia, Supraventricular; Tomography, X-Ray Computed | 1998 |
Acute effects of thyroid hormone analogs on sodium currents in neonatal rat myocytes.
Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Animals, Newborn; Cells, Cultured; Heart; Membrane Potentials; Monoiodotyrosine; Myocardium; Propranolol; Rats; Receptors, Thyroid Hormone; Sodium; Structure-Activity Relationship; Thyroid Hormones; Triiodothyronine, Reverse | 1999 |
Structure-activity relationship of P-glycoprotein substrates and modifiers.
Topics: Adenosine Triphosphatases; Amiodarone; Amitriptyline; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Daunorubicin; Diltiazem; Kinetics; Micelles; Progesterone; Propranolol; Structure-Activity Relationship; Verapamil; Vinblastine | 2000 |
Oral amiodarone and atrial fibrillation.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Humans; Patient Selection; Propranolol; Sotalol; Tachycardia, Supraventricular; Treatment Outcome | 2001 |
Fetal hydrops due to supraventricular tachycardia--successful outcome in a difficult case.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Hydrops Fetalis; Pregnancy; Propranolol; Tachycardia, Supraventricular | 2003 |
Verapamil sensitive idiopathic ventricular tachycardia in an infant.
Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Resistance; Drug Therapy, Combination; Electrocardiography; Female; Humans; Infant; Lidocaine; Propranolol; Tachycardia, Ventricular; Verapamil | 2003 |
Suppression by propranolol and amiodarone of an electrical storm refractory to metoprolol and amiodarone.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Dose-Response Relationship, Drug; Drug Therapy, Combination; Equipment Failure; Follow-Up Studies; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propranolol; Recurrence; Tachycardia, Ventricular; Treatment Failure | 2005 |
Effects of antiarrhythmic drugs on apoptotic pathways in H9c2 cardiac cells.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Caspases; Cell Line; Clone Cells; Diploidy; DNA Fragmentation; Dose-Response Relationship, Drug; Lidocaine; Membrane Potentials; Mitochondrial Membranes; Propranolol; Pyrimidinones; Signal Transduction; Time Factors; Verapamil | 2006 |
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil | 2007 |
[Congenital junctional ectopic tachycardia. Pharmacologic management during infancy].
Topics: Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Propranolol; Retrospective Studies; Tachycardia, Ectopic Junctional; Treatment Outcome | 2011 |
Intraosseous infusion is unreliable for adenosine delivery in the treatment of supraventricular tachycardia.
Topics: Adenosine; Amiodarone; Catheterization, Central Venous; Combined Modality Therapy; Drug Therapy, Combination; Emergencies; Humans; Infant; Infusions, Intraosseous; Infusions, Intravenous; Male; Procainamide; Propranolol; Recurrence; Sotalol; Tachycardia, Supraventricular; Treatment Failure; Vagus Nerve Stimulation | 2012 |
[Effect of anti-arrhythmia drugs on mouse arrhythmia induced by Bufonis Venenum].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bufanolides; Electrocardiography; Female; Heart Rate; In Vitro Techniques; Lethal Dose 50; Lidocaine; Male; Mice; Phenytoin; Propranolol; Verapamil | 2011 |
Insights from preclinical ultra high-density electroanatomical sinus node mapping.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function, Right; Electrophysiologic Techniques, Cardiac; Epicardial Mapping; Heart Atria; Metaproterenol; Propranolol; Sinoatrial Node; Swine | 2015 |
Phenotype classification of zebrafish embryos by supervised learning.
Topics: Amiodarone; Animals; Automation; Embryo, Nonmammalian; Image Processing, Computer-Assisted; Larva; Machine Learning; Phenotype; Propranolol; Zebrafish | 2015 |
Investigation of the antifibrillatory drug interactions between Amiodarone and Ibutilide in isolated, perfused Rabbit hearts.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Interactions; Heart; Lidocaine; Perfusion; Propranolol; Rabbits; Reproducibility of Results; Sulfonamides; Ventricular Fibrillation | 2015 |
The use of flecainide in critical neonates and infants with incessant supraventricular tachycardias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Drug Therapy, Combination; Female; Flecainide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Propanolamines; Propranolol; Retrospective Studies; Tachycardia, Supraventricular; Treatment Outcome | 2015 |
Ventricular Extrasystoles after First Dose of Sofosbuvir in a Patient Treated with Propranolol but not with Amiodarone: A Case Report.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antiviral Agents; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography; Hepatitis C, Chronic; Humans; Male; Propranolol; Sofosbuvir; Ventricular Premature Complexes | 2017 |
Molecular interaction of some cardiovascular drugs with human serum albumin at physiological-like conditions: A new approach.
Topics: Amiodarone; Atenolol; Captopril; Cardiovascular Agents; Humans; Hydrophobic and Hydrophilic Interactions; Propranolol; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Static Electricity; Timolol | 2018 |
Nonreentrant atrial tachycardia occurs independently of hypertrophic cardiomyopathy in RASopathy patients.
Topics: Amiodarone; Arrhythmias, Cardiac; Calcium; Cardiomyopathy, Hypertrophic; Costello Syndrome; Digoxin; Female; Humans; Infant; Infant, Newborn; LEOPARD Syndrome; Male; Noonan Syndrome; Propranolol; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); ras Proteins; SOS1 Protein; Tachycardia, Ectopic Atrial | 2018 |
Triple Antiarrhythmic Therapy in Newborns with Refractory Atrioventricular Reentrant Tachycardia.
Topics: Amiodarone; Anti-Arrhythmia Agents; Flecainide; Humans; Infant; Infant, Newborn; Propranolol; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Supraventricular | 2023 |