Compounds > amiodarone

amiodarone and paclitaxel

amiodarone has been researched along with paclitaxel in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	12 (63.16)	29.6817
2010's	7 (36.84)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ando, M; Hanioka, N; Murayama, N; Ozawa, S; Saito, Y; Sawada, J; Soyama, A	1
Constantinides, PP; Kessler, DR; Tustian, A	1
Dansette, PM; Jaouen, M; Johnson, EF; Macherey, AC; Mansuy, D; Marques-Soares, C; Melet, A; Sari, MA; Schoch, GA	1
Ekman, S; Fransson-Steen, R; Hagbjörk, AL; Löfgren, S; Terelius, Y	1
Itoh, Y; Oishi, R; Sendo, T	1
Cesana, P; Conen, K; Gotta, V; Hammann, F; Medinger, M; Rochlitz, C; Taegtmeyer, AB	1
Donovan, JW; Kane, B; Kane, K; Pierog, J	1

Reviews

3 review(s) available for amiodarone and paclitaxel

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Tocol emulsions for drug solubilization and parenteral delivery. Advanced drug delivery reviews, 2004, May-07, Volume: 56, Issue:9 Topics: Amiodarone; Chemistry, Pharmaceutical; Clinical Trials as Topic; Drug Carriers; Emulsions; Fat Emulsions, Intravenous; Humans; Paclitaxel; Solubility; Tocopherols; Tocotrienols	2004
[Drug-induced lung diseases]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2006, Volume: 127, Issue:6 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antirheumatic Agents; Contrast Media; Drugs, Chinese Herbal; Gefitinib; Granulocyte Colony-Stimulating Factor; Humans; Interferons; Iodine Radioisotopes; Lung Diseases, Interstitial; Minocycline; Paclitaxel; Quinazolines	2006

Other Studies

16 other study(ies) available for amiodarone and paclitaxel

Article	Year
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Amiodarone N-deethylation by CYP2C8 and its variants, CYP2C83 and CYP2C8 P404A. Pharmacology & toxicology, 2002, Volume: 91, Issue:4* Topics: Amiodarone; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Metabolic Clearance Rate; Microsomes, Liver; Paclitaxel; Structure-Activity Relationship; Transfection	2002
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants. Biochemistry, 2004, Dec-14, Volume: 43, Issue:49 Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone	2004
Metabolism of human cytochrome P450 marker substrates in mouse: a strain and gender comparison. Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:9 Topics: Amiodarone; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme System; Dextromethorphan; Diclofenac; DNA, Complementary; Ethanolamines; Female; Humans; Kinetics; Lauric Acids; Male; Mephenytoin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrophenols; Oxidoreductases, N-Demethylating; Oxygen; Paclitaxel; Phenacetin; Rats; Sex Factors; Species Specificity; Substrate Specificity; Testosterone	2004
Pharmacokinetic interaction between taxanes and amiodarone leading to severe toxicity. British journal of clinical pharmacology, 2017, Volume: 83, Issue:4 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Ductal, Breast; Combined Modality Therapy; Docetaxel; Drug Interactions; Female; Humans; Paclitaxel; Taxoids; Time Factors; Trastuzumab	2017
Management of isolated yew berry toxicity with sodium bicarbonate: a case report in treatment efficacy. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Antidotes; Drug Therapy, Combination; Electrocardiography; Humans; Injections, Intravenous; Male; Plant Poisoning; Seizures; Sodium Bicarbonate; Tachycardia, Ventricular; Taxus; Treatment Outcome; Young Adult	2009