amiodarone and mexiletine

amiodarone has been researched along with mexiletine in 123 studies

Research

Studies (123)

Timeframe	Studies, this research(%)	All Research%
pre-1990	76 (61.79)	18.7374
1990's	16 (13.01)	18.2507
2000's	13 (10.57)	29.6817
2010's	15 (12.20)	24.3611
2020's	3 (2.44)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Bruno, C; Budriesi, R; Carbonara, R; Carocci, A; Catalano, A; Colabufo, NA; Conte Camerino, D; De Palma, A; Desaphy, JF; Di Mola, A; Franchini, C; Ghelardini, C; Lentini, G; Perrone, MG	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Theisen, K	1
Coumel, P; Krikler, D; Rosen, MR; Wellens, HJ; Zipes, DP	1
Troup, PJ; Zipes, DP	2
Koch-Weser, J	1
Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA	1
Jung, W; Lüderitz, B; Manz, M	1
Baĭer, T; Brakhmann, I; Khilbel, T; Kiubler, V; Shmitt, K; Valdeker, B	1
Jung, W; Lüderitz, B; Manz, M; Pfeiffer, D; Pizzulli, L	1
Deiwick, M; Konertz, W; Scheld, HH; Weyand, M	1
Autenrieth, G; Bach, P; Gonschior, P; Kreuzer, E; Prinz, C; Steinbeck, G	1
Fomina, IG; Iankin, VV	1
Kokkas, B; Kotoula, M; Morali, A; Papadopoulos, K; Paradelis, A; Sphakianaki, E; Tsouderos, I	1
Korkushko, OV; Shatilo, VB	1
Bero, CJ; Rihn, TL	1
Kadish, A; Morady, F; Toivonen, L	1
Clément, DL; François, B; Jordaens, L	1
Leffler, J; Lüderitz, B; Nitsch, J	1
Roden, DM	1
Brignole, M; Lolli, G; Menozzi, C; Monducci, I	1
Kates, RE; Liem, LB	1
Grauer, K; Gums, J; Skluth, H	1
James, MA; Jones, JV; Papouchado, P	1
Comer, T; Saliba, D; Stanley, R; Taylor, JL	1
Yamaguchi, I	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Roy, D	1
Anderson, JL	1
Hussar, DA	1
Belhassen, B; Laniado, S; Pines, A	1
Andersson, KE; Wettrell, G	1
Morganroth, J; Nestico, PF	2
Huang, SK; Marcus, FI	1
Garson, A; Moak, JP; Smith, RT	1
Horowitz, LN; Morganroth, J	1
Hammill, SC; Kreeger, RW	1
Lanza, GA; Lucente, M; Mondello Malvestiti, FM; Rebuzzi, AG; Tamburi, S	1
Elharrar, V; Nakaya, Y; Surawicz, B	1
Chlewicka, I; Paczkowski, D; Podleśny, J; Popławska, W; Walczak, F; Wójcik, E	1
Horowitz, LN; Kay, HR; Kutalek, SP; Rae, AP; Spielman, SR	1
Campbell, RW	1
Cook, TS; DiMarco, JP; Nygaard, TW; Sellers, TD	1
Schwartz, PJ; Vanoli, E	1
Bilancini, A; Blandini, A; Costantini, C; Curzi, G; Massacci, C; Pigini, G; Purcaro, A	1
Pepper, GA	1
Flaker, GC; Moser, SA	1
Feld, G; Hendrickson, J; Heng, MK; Intarachot, V; Nademanee, K; Singh, BN; Yale, C	1
Podrid, PJ	1
Fukuzaki, H; Itoh, S; Kobayashi, K	1
Bandieri, JD; Chiale, PA; Elizari, MV; Haedo, AH; Lázzari, JO; Rosenbaum, MB	1
Schwartz, PJ; Vanoli, E; Zaza, A; Zuanetti, G	1
Greenspan, AM; Horowitz, LN; Rae, AP; Sokoloff, NM; Spielman, SR; Webb, CR	1
Campanari, G; Ferroni, C; Marini, M; Paciaroni, E	1
Gang, ES; Hamer, A; Mandel, WJ; Oseran, DS; Peter, T; Rosenthal, ME	1
Adinolfi, L; Bonaduce, D; Chiariello, M; Dote, I; Golia, B; Masullo, LA	1
Sanna, GP	1
Opie, LH	1
Lawrie, TD	1
Burckhardt, D; Follath, F; Hoffmann, A	1
Hillis, WS; Whiting, B	1
Somberg, JC	1
Ceci, V; Di Marcotullio, G; Dini, P; Milazzotto, F; Polizzi, C; Santini, M	1
Lüderitz, B; Manz, M; Steinbeck, G	2
Doherty, JU; Josephson, ME; Kienzle, MG; Williams, PD; Zygmont, D	1
Jahrmärker, H; Theisen, K	1
Duff, HJ; Oates, JA; Roden, DM; Woosley, RL	1
Mohiuddin, SM; Ross, WB	1
Lüderitz, B	1
Rosen, MR; Wit, AL	1
Block, PJ; Winkle, RA	1
Laser, J	1
Rossi, L	1
Harrison, DC; Mead, RH	1
Heger, JJ; Prystowsky, EN; Zipes, DP	1
Luck, JC; Mann, DE; Pratt, CM; Wyndham, CR	1
Ambrosini, F; Finzi, A; Lo Masto, M; Lotto, A; Massari, FM; Pagnoni, F; Valentini, R	1
Burckhardt, D; Follath, F; Hoffmann, A; Schütz, E; White, R	1
Jewitt, DE	1
Benchimol, A; Desser, KB	1
Cho, YW; Kuemmerle, HP; Singh, BN	1
Nademanee, K; Singh, BN	1
Bonatti, V; Botti, G; Disertori, M; Furlanello, F; Guarnerio, M; Inama, G; Rolli, A; Vergara, G	1
Flaker, GC; Munuswamy, K	1
Bär, FW; Brugada, P; Friedman, PL; Kuck, KH; Wellens, HJ	1
Demoulin, JC; Kulbertus, HE; Legrand, V; Mary-Rabine, L; Waleffe, A	1
Jung, W; Lüderitz, B; Manz, M; Pfeiffer, D; Pizzulli, L; Tebbenjohanns, J	1
Jung, W; Lüderitz, B; Manz, M; Mletzko, R; Nitsch, J	1
Alvarez, L; Escudero, C; Millán, I; Torralba, A	1
Schuster, MM	1
Katsivas, AG; Manolis, AG; Tsatiris, CG; Vassilopoulos, C	1
Bogáts, G; Hála, O; Iost, N; Mátyus, P; Opincariu, M; Papp, JG; Szécsi, J; Szenohradszky, P; Szolnoki, J; Varró, A; Virág, L	1
Hashimoto, H; Kamakura, S; Komamura, K; Matsumoto, K; Miyatake, K; Tachibana, M; Tanaka, K; Ueno, K; Yonezawa, E	1
Hennersdorf, MG; Niebch, V; Perings, C; Strauer, BE; Vester, EG; Winter, J	1
Cai, Y; Jia, J; Li, S; Liu, G; Liu, Y; Pan, C; Ren, J; Yu, C	1
Eroğlu, S; Müderrisoğlu, H; Ozbiçer, S; Ozin, B	1
Anderson, JL; Bair, TL; Bunch, TJ; Crandall, BG; Day, JD; Lappe, DL; Mader, KM; Mahapatra, S; May, HT; Molden, J; Muhlestein, JB; Murdock, D; Osborn, JS; Weiss, JP	1
Honjo, H; Kamiya, K; Kato, S; Morishima, M; Suzuki, T; Ueda, N	1
Ahmad, K; Alshengeiti, L; Aves, T; Dorian, P; Gao, D; Golovchiner, G; Korley, V; Mangat, I; Pinter, A; Van Herendael, H	1
Johnson-Davis, KL; Slawson, MH	1
Al-Khatib, SM; Allen LaPointe, NM; Curtis, LH; Hammill, BG; Mi, X; Pokorney, SD	1
Deyell, MW; Doucette, S; Essebag, V; Gardner, M; Gray, C; Healey, JS; Hruczkowski, T; Leong-Sit, P; Nault, I; Nery, PB; Parkash, R; Rivard, L; Sapp, JL; Steinberg, C; Sterns, LD	1
Acosta-Martínez, J; Arana-Rueda, E; Frutos-López, M; Pedrote, A	1
Bilato, C; Cavedon, S; Mecenero, A; Mugnai, G; Paolini, C; Perrone, C	1
Anic, A; Boveda, S; Conte, G; de Asmundis, C; Farkowski, MM; Karlinski, M; Lewandowski, M; Marijon, E; Mugnai, G; Providencia, R; Pytkowski, M	1

Reviews

26 review(s) available for amiodarone and mexiletine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New antiarrhythmic agents: amiodarone, aprindine, disopyramide, ethmozin, mexiletine, tocainide, verapamil. The American journal of cardiology, 1978, May-22, Volume: 41, Issue:6 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Disopyramide; Electrophysiology; Humans; Mexiletine; Morpholines; Phenothiazines; Verapamil	1978
Prevention of sudden coronary death by chronic antiarrhythmic therapy. Advances in cardiology, 1978, Volume: 25 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Disopyramide; Drug Evaluation; Humans; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Time Factors; Ventricular Fibrillation	1978
[Ventricular tachycardia in anterior wall aneurysm after myocardial infarct]. Der Internist, 1992, Volume: 33, Issue:11 Topics: Aged; Amiodarone; Drug Therapy, Combination; Electrocardiography, Ambulatory; Heart Aneurysm; Heart Ventricles; Humans; Male; Mexiletine; Myocardial Infarction; Postoperative Complications; Tachycardia, Ventricular	1992
Update: cardiac antiarrhythmic drugs. Comprehensive therapy, 1989, Volume: 15, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Propafenone; Propanolamines	1989
Ventricular arrhythmias. An assessment of newer therapeutic agents. Postgraduate medicine, 1989, May-01, Volume: 85, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Flecainide; Humans; Lidocaine; Mexiletine; Tocainide; United States	1989
[The interaction of antiarrhythmic drugs with other drugs]. Kokyu to junkan. Respiration & circulation, 1985, Volume: 33, Issue:8 Topics: Adrenergic beta-Agonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Digoxin; Drug Interactions; Humans; Lidocaine; Mexiletine; Phenytoin; Procainamide; Quinidine	1985
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drugs. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2 Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1986
Rationale of combination antiarrhythmic drug therapy. Cardiovascular clinics, 1985, Volume: 16, Issue:1 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Digitalis Glycosides; Drug Therapy, Combination; Humans; Mexiletine; Myocardial Infarction; Quinidine; Tachycardia; Verapamil	1985
Cardiovascular drugs. I: Antidysrhythmic drugs. Therapeutic drug monitoring, 1986, Volume: 8, Issue:1 Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Disopyramide; Drug Interactions; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Tocainide; Verapamil	1986
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment. Cardiology clinics, 1986, Volume: 4, Issue:2 Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
Antiarrhythmic agents for chronic ventricular arrhythmias. Comprehensive therapy, 1987, Volume: 13, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide	1987
New antiarrhythmic drugs: tocainide, mexiletine, flecainide, encainide, and amiodarone. Mayo Clinic proceedings, 1987, Volume: 62, Issue:11 Topics: Administration, Oral; Amiodarone; Anilides; Anti-Arrhythmia Agents; Drug Interactions; Encainide; Flecainide; Heart Conduction System; Humans; Lidocaine; Mexiletine; Tachycardia; Tocainide	1987
Antiarrhythmic drug therapy (Part 2). Benefits and hazards. Chest, 1985, Volume: 88, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1985
Comparison of newer antiarrhythmic agents. American heart journal, 1980, Volume: 100, Issue:6 Pt 2 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Disopyramide; Humans; Mexiletine; Tocainide; Verapamil	1980
Antiarrhythmic drug therapy for sustained ventricular tachycardia. Heart & lung : the journal of critical care, 1984, Volume: 13, Issue:6 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bethanidine; Calcium Channel Blockers; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Encainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Phenytoin; Piperidines; Procainamide; Quinidine; Tachycardia; Tocainide	1984
[Medical treatment of extrasystole and tachycardia (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1980, Jan-18, Volume: 122, Issue:3 Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil	1980
Electropharmacology of antiarrhythmic drugs. American heart journal, 1983, Volume: 106, Issue:4 Pt 2 Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil	1983
Hemodynamic effects of antiarrhythmic drugs. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide	1983
Therapy with investigational antiarrhythmic drugs. The Medical clinics of North America, 1984, Volume: 68, Issue:5 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Tocainide	1984
Investigational antiarrhythmic drugs for the treatment of ventricular rhythm disturbances. Cardiology clinics, 1984, Volume: 2, Issue:1 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Tocainide	1984
Hemodynamic effects of newer antiarrhythmic drugs. American heart journal, 1980, Volume: 100, Issue:6 Pt 2 Topics: Acebutolol; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Atenolol; Benzeneacetamides; Disopyramide; Dogs; Hemodynamics; Humans; Mexiletine; Piperidines; Tocainide; Verapamil	1980
Mexiletine for recurrent ventricular tachycardia in adult patients with structural heart disease and implantable cardioverter defibrillator: an EHRA systematic review. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2022, 10-13, Volume: 24, Issue:9 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Defibrillators, Implantable; Humans; Mexiletine; Prospective Studies; Retrospective Studies; Tachycardia, Ventricular; Treatment Outcome; Ventricular Fibrillation	2022

Trials

10 trial(s) available for amiodarone and mexiletine

Article	Year
Prevention of sudden coronary death by chronic antiarrhythmic therapy. Advances in cardiology, 1978, Volume: 25 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Disopyramide; Drug Evaluation; Humans; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Time Factors; Ventricular Fibrillation	1978
Effects of chronic amiodarone therapy on defibrillation threshold. The American journal of cardiology, 1992, Oct-15, Volume: 70, Issue:11 Topics: Amiodarone; Defibrillators, Implantable; Electrodes, Implanted; Female; Follow-Up Studies; Humans; Male; Mexiletine; Middle Aged; Multivariate Analysis; Prospective Studies; Tachycardia, Ventricular; Ventricular Fibrillation	1992
[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes]. Klinicheskaia meditsina, 1992, Volume: 70, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Pre-Excitation Syndromes; Procainamide; Propranolol; Quinidine; Time Factors; Verapamil	1992
[Comparison of the anti-arrhythmic effectiveness of ethacizine, ethmozine, cordarone, mexitil and ritmilen in elderly patients with ventricular extrasystole]. Kardiologiia, 1990, Volume: 30, Issue:11 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Heart Ventricles; Humans; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Placebos	1990
Combined anti-arrhythmic therapy with class 1 and class 3 drugs. Postgraduate medical journal, 1989, Volume: 65, Issue:766 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Humans; Male; Mexiletine; Middle Aged; Randomized Controlled Trials as Topic; Single-Blind Method	1989
Electrophysiologic assessment of antiarrhythmic drug efficacy for ventricular tachyarrhythmias associated with dilated cardiomyopathy. The American journal of cardiology, 1987, Feb-01, Volume: 59, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Procainamide; Quinidine; Tachycardia; Time Factors; Ventricular Fibrillation	1987
Mexiletine: double-blind comparison with procainamide in PVC suppression and open-label sequential comparison with amiodarone in life-threatening ventricular arrhythmias. American heart journal, 1985, Volume: 110, Issue:5 Topics: Adult; Aged; Amiodarone; Arrhythmia, Sinus; Benzofurans; Clinical Trials as Topic; Digestive System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Mexiletine; Middle Aged; Procainamide; Propylamines	1985
Selection of an antiarrhythmic drug for a sudden-death-prevention trial. American heart journal, 1982, Volume: 103, Issue:4 Pt 2 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Moricizine; Morpholines; Phenothiazines; Piperidines; Tocainide; Verapamil	1982
[Long-term drug therapy in ventricular cardiac arrhythmias. Is an improvement of the prognosis possible?]. Deutsche medizinische Wochenschrift (1946), 1983, Nov-04, Volume: 108, Issue:44 Topics: Adult; Aged; Amiodarone; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Long-Term Care; Mexiletine; Middle Aged; Tachycardia	1983
Mexiletine or catheter ablation after amiodarone failure in the VANISH trial. Journal of cardiovascular electrophysiology, 2018, Volume: 29, Issue:4 Topics: Action Potentials; Aged; Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Drug Substitution; Female; Heart Rate; Humans; Male; Mexiletine; Middle Aged; Myocardial Ischemia; Tachycardia, Ventricular; Time Factors; Treatment Failure	2018

Other Studies

88 other study(ies) available for amiodarone and mexiletine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Synthesis and toxicopharmacological evaluation of m-hydroxymexiletine, the first metabolite of mexiletine more potent than the parent compound on voltage-gated sodium channels. Journal of medicinal chemistry, 2012, Feb-09, Volume: 55, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Aorta; Ataxia; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Caco-2 Cells; Guinea Pigs; Heart; Heart Rate; HEK293 Cells; Humans; Ion Channel Gating; Mexiletine; Mice; NAV1.5 Voltage-Gated Sodium Channel; Permeability; Sodium Channels; Stereoisomerism; Vasodilator Agents	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Drug therapy of tachyarrhythmias (author's transl)]. Klinische Wochenschrift, 1978, Feb-15, Volume: 56, Issue:4 Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil	1978
Newer antiarrhythmic drugs. Pacing and clinical electrophysiology : PACE, 1978, Volume: 1, Issue:4 Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Child; Edrophonium; Electrophysiology; Heart Conduction System; Heart Ventricles; Humans; Injections, Intravenous; Lidocaine; Mexiletine; Recurrence; Tachycardia; Tocainide; Verapamil; Wolff-Parkinson-White Syndrome	1978
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses. Drugs, 1978, Volume: 15, Issue:4 Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil	1978
New antiarrhythmic drugs. Comprehensive therapy, 1978, Volume: 4, Issue:11 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Humans; Lidocaine; Mexiletine; Papaverine; Phenothiazines	1978
[Combination anti-arrhythmic drug therapy]. Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4 Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography, Ambulatory; Encainide; Flecainide; Humans; Mexiletine; Sotalol; Tachycardia; Tocainide	1992
[Anti-arrhythmia agents in heart failure]. Kardiologiia, 1992, Volume: 32, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Flecainide; Humans; Mexiletine; Middle Aged; Propafenone; Quinidine	1992
Is pretransplant antiarrhythmic drug therapy a risk factor? Transplantation proceedings, 1992, Volume: 24, Issue:6 Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Cause of Death; Child; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; Mexiletine; Middle Aged; Postoperative Complications; Premedication; Propafenone; Quinidine; Sotalol; Survival Rate; Transplantation, Heterotopic	1992
Interactions between digitoxin and some antiarrhythmic drugs. Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:5 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Digitoxin; Drug Interactions; Female; Male; Mexiletine; Propafenone; Rabbits; Radioimmunoassay	1992
Possible association of pulmonary fibrosis with mexiletine. DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:12 Topics: Aged; Amiodarone; Humans; Male; Mexiletine; Pulmonary Fibrosis; Tachycardia; Tomography, X-Ray Computed	1991
A prospective comparison of class IA, B, and C antiarrhythmic agents in combination with amiodarone in patients with inducible, sustained ventricular tachycardia. Circulation, 1991, Volume: 84, Issue:1 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electrocardiography; Encainide; Heart Conduction System; Humans; Mexiletine; Prospective Studies; Quinidine; Tachycardia	1991
[Tachycardia with wide ventricular complexes and alternating QRS complexes and RR intervals]. Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:14 Topics: Amiodarone; Cardiac Pacing, Artificial; Electric Countershock; Electrocardiography; Humans; Male; Mexiletine; Middle Aged; Tachycardia; Tachycardia, Atrioventricular Nodal Reentry	1990
[Acute myocardial uptake of lidocaine, mexiletine and amiodarone]. Klinische Wochenschrift, 1990, Jul-05, Volume: 68, Issue:13 Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Catheterization; Coronary Disease; Humans; Injections, Intravenous; Lidocaine; Mexiletine; Myocardium; Time Factors	1990
Antiarrhythmic drugs. Clinical pharmacology of the old and the new agents. Postgraduate medicine, 1985, Sep-15, Volume: 78, Issue:4 Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Delayed-Action Preparations; Disopyramide; Heart Arrest; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Resuscitation; Tocainide	1985
Noninvasive serial electrophysiological testing using an implanted pacemaker for management of recurrent ventricular tachycardia. Pacing and clinical electrophysiology : PACE, 1986, Volume: 9, Issue:4 Topics: Aged; Amiodarone; Electrophysiology; Heart Ventricles; Humans; Male; Mexiletine; Pacemaker, Artificial; Propafenone; Propiophenones; Recurrence; Sinoatrial Node; Tachycardia	1986
Mexiletine-theophylline interaction. The American journal of medicine, 1989, Volume: 86, Issue:6 Pt 1 Topics: Aged; Amiodarone; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Lung Diseases, Obstructive; Male; Mexiletine; Theophylline	1989
New drugs for use in 1987--Part Two. Pennsylvania medicine, 1987, Volume: 90, Issue:6 Topics: Amiodarone; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Buspirone; Central Nervous System Depressants; Enalapril; Humans; Mexiletine; Pyrimidines	1987
Failure of corticosteroid therapy to prevent induction of ventricular tachycardia in sarcoidosis. Chest, 1989, Volume: 95, Issue:4 Topics: Adult; Amiodarone; Cardiac Pacing, Artificial; Cardiomyopathies; Disopyramide; Drug Therapy, Combination; Electrophysiology; Fluocortolone; Humans; Male; Mexiletine; Quinidine; Sarcoidosis; Tachycardia	1989
Newer antiarrhythmic drugs in children. American heart journal, 1987, Volume: 113, Issue:1 Topics: Adolescent; Adult; Amiodarone; Anilides; Arrhythmias, Cardiac; Child; Child, Preschool; Electrocardiography; Encainide; Humans; Infant; Mexiletine; Moricizine; Phenothiazines; Propafenone	1987
Second generation antiarrhythmic agents: have we reached antiarrhythmic Nirvana? Journal of the American College of Cardiology, 1987, Volume: 9, Issue:2 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Tocainide	1987
[Worsening of ventricular arrhythmia in the dynamic ECG in patients treated with anti-arrhythmia drugs]. Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:6 Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Monitoring, Physiologic; Propafenone	1988
Effect of mexiletine, amiodarone and disopyramide on the excitability and refractoriness of canine cardiac fibers: possible relation to antiarrhythmic drug action and classification. Cardiovascular drugs and therapy, 1987, Volume: 1, Issue:2 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Female; Heart; In Vitro Techniques; Male; Mexiletine; Neurons; Papillary Muscles; Purkinje Fibers; Refractory Period, Electrophysiological	1987
[Remote results of the pharmacological treatment of patients with a high risk of sudden heart arrest in ventricular disorders of cardiac rhythm]. Kardiologia polska, 1987, Volume: 30, Issue:10-11 Topics: Adult; Aged; Amiodarone; Death, Sudden; Female; Heart Arrest; Humans; Male; Mexiletine; Middle Aged; Risk Factors; Tachycardia, Supraventricular; Time Factors; Ventricular Fibrillation	1987
Arrhythmogenesis--a European perspective. The American journal of cardiology, 1987, Apr-30, Volume: 59, Issue:11 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Utilization; Europe; Humans; Mexiletine; Sotalol; United States	1987
Adverse reactions to antiarrhythmic drugs during therapy for ventricular arrhythmias. JAMA, 1986, Jul-04, Volume: 256, Issue:1 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Procainamide; Prospective Studies; Quinidine; Tachycardia; Ventricular Fibrillation	1986
An experimental approach to the choice of antiarrhythmic therapy. European heart journal, 1986, Volume: 7 Suppl A Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil	1986
[Anti-arrhythmic efficacy of the amiodarone-mexiletine combination in the treatment of resistant complex ventricular arrhythmias]. Giornale italiano di cardiologia, 1986, Volume: 16, Issue:5 Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Propylamines	1986
New antiarrhythmic agents. The Nurse practitioner, 1986, Volume: 11, Issue:7 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Flecainide; Humans; Kinetics; Mexiletine; Patient Education as Topic; Piperidines	1986
Get ready. The new antiarrhythmics are coming. Nursing, 1985, Volume: 15, Issue:9 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Humans; Mexiletine	1985
[Anti-arrhythmia agents (II): Mexiletine, aprindine, tocainide and amiodarone]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:11 Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Humans; Lidocaine; Mexiletine; Tocainide	1985
Comparative antiarrhythmic efficacy of verapamil, 17-monochloracetylajmaline, mexiletine and amiodarone in patients with severe chagasic myocarditis: relation with the underlying arrhythmogenic mechanisms. Journal of the American College of Cardiology, 1986, Volume: 7, Issue:5 Topics: Adult; Ajmaline; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chagas Cardiomyopathy; Female; Humans; Male; Mexiletine; Middle Aged; Placebos; Propylamines; Verapamil	1986
The effect of antiarrhythmic drugs on life-threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity. American heart journal, 1985, Volume: 109, Issue:5 Pt 1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Disease Models, Animal; Electrocardiography; Hemodynamics; Lidocaine; Mexiletine; Prazosin; Propranolol; Stellate Ganglion	1985
Limitations of failure of procainamide during electrophysiologic testing to predict response to other medical therapy. Journal of the American College of Cardiology, 1985, Volume: 6, Issue:2 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Electric Stimulation; Electrophysiology; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Procainamide; Quinidine; Time Factors	1985
[Monitoring of anti-arrhythmia drugs with the Holter system and the determination of their blood levels (mexiletine (mexitil) and amiodarone)]. Minerva cardioangiologica, 1985, Volume: 33, Issue:5 Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Evaluation; Drug Tolerance; Electrocardiography; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Monitoring, Physiologic; Propylamines	1985
The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias. American heart journal, 1985, Volume: 110, Issue:5 Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Electrophysiology; Female; Heart Arrest; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Mitral Valve Prolapse; Procainamide; Propafenone; Propiophenones; Propranolol; Risk	1985
[Ventricular tachycardia]. Minerva medica, 1985, Nov-17, Volume: 76, Issue:44 Topics: Amiodarone; Aprindine; Digitalis Glycosides; Electrocardiography; Heart Aneurysm; Heart Ventricles; Humans; Mexiletine; Pacemaker, Artificial; Propranolol; Quinidine; Risk; Tachycardia; Tachycardia, Paroxysmal	1985
New drugs in the management of ventricular arrhythmias. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Drug Interactions; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1984
Drugs and the heart. IV. Antiarrhythmic agents. Lancet (London, England), 1980, Apr-19, Volume: 1, Issue:8173 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil	1980
Safe treatment of resistant ventricular arrhythmias with a combination of amiodarone and quinidine or mexiletine. Lancet (London, England), 1983, Mar-26, Volume: 1, Issue:8326 Pt 1 Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Therapy, Combination; Female; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Quinidine	1983
Antiarrhythmic drugs. British medical journal (Clinical research ed.), 1983, Apr-23, Volume: 286, Issue:6374 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil	1983
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
[Combinations of some anti-arrhythmia drugs]. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:5 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Humans; Mexiletine; Propafenone; Propiophenones; Quinidine	1984
[Sudden heart death in ventricular heart rhythm disorders: possibilities and limits of long-term therapy]. Der Internist, 1984, Volume: 25, Issue:7 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden; Disopyramide; Germany, West; Humans; Mexiletine; Risk; Time Factors; Ventricular Fibrillation	1984
Antiarrhythmic therapy: new additions and future expectations. Geriatrics, 1983, Volume: 38, Issue:1 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Bretylium Tosylate; Disopyramide; Encainide; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil	1983
[Drug therapy of arrhythmia in coronary cardiopathy]. La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Tachycardia; Tocainide	1983
Intractable tachycardia and a dead battery. Hospital practice (Office ed.), 1984, Volume: 19, Issue:10 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Benzeneacetamides; Electric Countershock; Electric Injuries; Electric Power Supplies; Humans; Male; Mexiletine; Pacemaker, Artificial; Piperidines; Tachycardia; Time Factors	1984
Nursing care for survivors of sudden cardiac death. The Nursing clinics of North America, 1984, Volume: 19, Issue:3 Topics: Adaptation, Psychological; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Arrest; Heart Conduction System; Humans; Lidocaine; Mexiletine; Moricizine; Nursing Assessment; Phenothiazines; Tocainide	1984
Drug therapy of cardiac arrhythmias. Cardiology clinics, 1983, Volume: 1, Issue:2 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Biological Availability; Encainide; Half-Life; Humans; Imidazoles; Intestinal Absorption; Kinetics; Lidocaine; Metabolic Clearance Rate; Mexiletine; Propafenone; Propiophenones; Protein Binding; Tachycardia; Tocainide	1983
Hemodynamic effects of antiarrhythmic drugs in acute myocardial infarction. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Central Venous Pressure; Female; Heart Rate; Hemodynamics; Humans; Male; Mexiletine; Myocardial Infarction; Propafenone; Propiophenones; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance	1984
Suppression of high-grade ventricular ectopic activity by antiarrhythmic drug treatment as a marker for survival in patients with chronic coronary artery disease. American heart journal, 1984, Volume: 107, Issue:6 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; Male; Mexiletine; Middle Aged; Phenytoin; Prognosis; Quinidine; Retrospective Studies	1984
New drugs for treating cardiac arrhythmias. Postgraduate medicine, 1981, Volume: 69, Issue:1 Topics: Acebutolol; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide; Heart Ventricles; Humans; Mexiletine; Moricizine; Morpholines; Phenothiazines; Tocainide; Verapamil	1981
Clinical pharmacology of antiarrhythmic drugs: a review and overview, part II. International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:5 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Propranolol; Tocainide	1981
Advances in antiarrhythmic therapy. The role of newer antiarrhythmic drugs. JAMA, 1982, Jan-08, Volume: 247, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Atrioventricular Node; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil	1982
[Validity and limits of invasive pharmacological tests in the treatment of malignant ventricular hyperkinetic arrhythmias]. Giornale italiano di cardiologia, 1983, Volume: 13, Issue:4 Topics: Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Female; Humans; Male; Mexiletine; Middle Aged; Propafenone; Propiophenones; Tachycardia	1983
New antiarrhythmic drugs. American family physician, 1982, Volume: 26, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Conduction System; Humans; Mexiletine; Verapamil	1982
Initiation of ventricular tachycardia by interpolated ventricular premature depolarizations. The American journal of cardiology, 1981, Volume: 48, Issue:5 Topics: Amiodarone; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Heart Conduction System; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Tachycardia	1981
Combined mexiletine and amiodarone treatment of refractory recurrent ventricular tachycardia. American heart journal, 1980, Volume: 100, Issue:6 Pt 1 Topics: Adult; Amiodarone; Benzofurans; Drug Therapy, Combination; Electric Stimulation; Follow-Up Studies; Humans; Male; Mexiletine; Middle Aged; Propylamines; Recurrence; Tachycardia	1980
Effects of antiarrhythmic drugs on epicardial defibrillation energy requirements and the rate of defibrillator discharges. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:1 Pt 2 Topics: Amiodarone; Defibrillators, Implantable; Electrodes, Implanted; Female; Follow-Up Studies; Humans; Male; Mexiletine; Middle Aged; Pericardium; Prospective Studies; Random Allocation; Time Factors; Ventricular Fibrillation	1993
Efficacy and safety of combination therapy with amiodarone and type I agents for treatment of inducible ventricular tachycardia. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:4 Pt 1 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Drug Therapy, Combination; Electrocardiography; Encainide; Female; Flecainide; Humans; Male; Mexiletine; Middle Aged; Prospective Studies; Stroke Volume; Tachycardia, Ventricular	1993
Electrophysiologic effects of procainamide, mexiletine, and amiodarone on the transplanted heart. Experimental study. The Journal of thoracic and cardiovascular surgery, 1995, Volume: 109, Issue:5 Topics: Amiodarone; Animals; Blood Pressure; Cardiac Output; Dogs; Electrocardiography; Heart Conduction System; Heart Transplantation; Hemodynamics; Mexiletine; Procainamide; Refractory Period, Electrophysiological; Transplantation, Heterotopic	1995
Management of incessant ventricular tachycardia in a 39-year-old woman with cardiomyopathy. American journal of critical care : an official publication, American Association of Critical-Care Nurses, 1997, Volume: 6, Issue:6 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Critical Illness; Defibrillators, Implantable; Electric Countershock; Female; Humans; Mexiletine; Tachycardia, Ventricular	1997
Electrical storms in an ICD-recipient with 429 delivered appropriate shocks: therapeutic management with antiarrhythmic drug combination. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2002, Volume: 6, Issue:1 Topics: Aged; Amiodarone; Cardiomyopathy, Dilated; Defibrillators, Implantable; Electrocardiography; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Mexiletine; Risk Assessment; Tachycardia, Ventricular; Treatment Outcome; Ventricular Fibrillation	2002
The cellular electrophysiologic effect of a new amiodarone like antiarrhythmic drug GYKI 16638 in undiseased human ventricular muscle: comparison with sotalol and mexiletine. Current medicinal chemistry, 2002, Volume: 9, Issue:1 Topics: Action Potentials; Adult; Amiodarone; Anti-Arrhythmia Agents; Electric Stimulation; Electrophysiology; Female; Heart; Humans; In Vitro Techniques; Kinetics; Male; Mexiletine; Papillary Muscles; Phenethylamines; Sotalol; Sulfonamides; Ventricular Function, Right	2002
Lack of interaction between amiodarone and mexiletine in cardiac arrhythmia patients. Journal of clinical pharmacology, 2002, Volume: 42, Issue:3 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bayes Theorem; Biological Availability; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Mexiletine; Middle Aged	2002
Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy. Cardiology, 2003, Volume: 99, Issue:4 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Electrophysiologic Techniques, Cardiac; Female; Follow-Up Studies; Heart Arrest; Humans; Male; Mexiletine; Middle Aged; Prognosis; Propafenone; Sotalol; Survivors; Time Factors; Treatment Outcome	2003
Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Mar-01, Volume: 847, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carbazoles; Carvedilol; Chromatography, Liquid; Diltiazem; Humans; Metoprolol; Mexiletine; Molecular Structure; Propanolamines; Propranolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry; Verapamil	2007
A case of myotonic dystrophy presenting with ventricular tachycardia and atrial fibrillation. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009, Volume: 37, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Defibrillators, Implantable; Electric Countershock; Electrocardiography; Female; Humans; Infusions, Intravenous; Mexiletine; Middle Aged; Myotonic Dystrophy; Propafenone; Tachycardia, Ventricular; Ultrasonography; Ventricular Dysfunction, Left	2009
Ranolazine reduces ventricular tachycardia burden and ICD shocks in patients with drug-refractory ICD shocks. Pacing and clinical electrophysiology : PACE, 2011, Volume: 34, Issue:12 Topics: Acetanilides; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Cohort Studies; Defibrillators, Implantable; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Humans; Hypoglycemia; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Ischemia; Piperazines; Ranolazine; Sotalol; Stroke Volume; Tachycardia, Ventricular; Treatment Outcome	2011
Atrial selectivity in Na+channel blockade by acute amiodarone. Cardiovascular research, 2013, Apr-01, Volume: 98, Issue:1 Topics: Action Potentials; Amiodarone; Animals; Heart Atria; Heart Conduction System; Male; Mexiletine; Myocytes, Cardiac; Rabbits; Sodium Channel Blockers	2013
Mexiletine as an adjunctive therapy to amiodarone reduces the frequency of ventricular tachyarrhythmia events in patients with an implantable defibrillator. Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; Cohort Studies; Combined Modality Therapy; Defibrillators, Implantable; Drug Monitoring; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Diseases; Humans; Incidence; Male; Mexiletine; Middle Aged; Ontario; Retrospective Studies; Tachycardia, Ventricular	2013
Quantitation of Flecainide, Mexiletine, Propafenone, and Amiodarone in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Methods in molecular biology (Clifton, N.J.), 2016, Volume: 1383 Topics: Amiodarone; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Flecainide; Humans; Mexiletine; Propafenone; Tandem Mass Spectrometry	2016
Use of Antiarrhythmic Medications in Medicare Part D Patients With an Implantable Cardioverter-Defibrillator and Ventricular Tachycardia. The American journal of cardiology, 2017, 05-01, Volume: 119, Issue:9 Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Databases, Factual; Death, Sudden, Cardiac; Defibrillators, Implantable; Electric Countershock; Female; Humans; Logistic Models; Male; Medicare Part D; Mexiletine; Ranolazine; Sodium Channel Blockers; Sotalol; Tachycardia, Ventricular; United States	2017
Dramatic reduction of ventricular tachycardia burden after dronedarone plus mexiletine treatment in a patient refractory to hybrid ablation. Revista portuguesa de cardiologia, 2020, Volume: 39, Issue:3 Topics: Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Defibrillators, Implantable; Dronedarone; Drug Therapy, Combination; Humans; Male; Mexiletine; Middle Aged; Tachycardia, Ventricular; Treatment Outcome	2020
Mexiletine for ventricular arrhythmias in patients with chronic coronary syndrome: a cohort study. Acta cardiologica, 2022, Volume: 77, Issue:3 Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Coronary Artery Disease; Defibrillators, Implantable; Female; Humans; Male; Mexiletine; Middle Aged; Myocardial Ischemia; Tachycardia, Ventricular; Ventricular Fibrillation	2022