amiodarone and methotrexate

amiodarone has been researched along with methotrexate in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (8.11)	18.7374
1990's	2 (5.41)	18.2507
2000's	11 (29.73)	29.6817
2010's	20 (54.05)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Aymard, B; Chabot, F; Cornette, A; Delorme, N; Gerard, H; Kheir, A; Lesur, O; Moreau, L; Polu, JM	1
Smith, GJ	1
Ward, MJ; White, JP	1
Crossley, J; Harman, RR; Jones, SK; Reynolds, NJ	1
Adler, M; Cremer, M; Henry, JP; Lecocq, E; Quiriny, M; Ros, P	1
Baudaun, N; Bonniaud, P; Camus, C; Camus, P; Fanton, A; Foucher, P	1
Brcakova, E; Cermanova, J; Chladek, J; Fuksa, L; Hroch, M; Kolouchova, G; Malakova, J; Martinkova, J; Micuda, S; Staud, F	1
Bischoff, A	1
Do, DV; Goldstein, DA; Le-Nguyen, XT; Lee, TK; Nguyen, QD; Rao, NA; Sepah, YJ; Vasconcelos-Santos, DV	1
Armstrong, S; Avery, AJ; Boyd, M; Cantrill, JA; Cresswell, K; Eden, M; Elliott, RA; Franklin, M; Howard, R; Kendrick, D; Morris, CJ; Prescott, RJ; Putman, K; Rodgers, S; Sheikh, A; Swanwick, G	1
Jindal, G; Rawat, A; Rohit, M; Singh, S; Suri, D	1
Larrain, S; Rinella, ME	1
Amacher, DE; Chalasani, N	1
Agra, Y; Moreno-Gómez, AM; Otero, MJ; Santos-Ramos, B	1
Guo, GL; Schumacher, JD	1
Li, S; Shi, J; Tang, H	1

Reviews

9 review(s) available for amiodarone and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The histopathology of pulmonary reactions to drugs. Clinics in chest medicine, 1990, Volume: 11, Issue:1 Topics: Amiodarone; Antirheumatic Agents; Biopsy; Bleomycin; Cyclophosphamide; Diagnosis, Differential; Eosinophilia; Humans; Lung; Lung Diseases; Methotrexate; Mitomycins; Organogold Compounds; Pulmonary Fibrosis	1990
Drug-induced adverse pulmonary reactions. Adverse drug reactions and acute poisoning reviews, 1985,Winter, Volume: 4, Issue:4 Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Humans; Hydrochlorothiazide; Hypertension, Pulmonary; Lung Diseases; Lupus Erythematosus, Systemic; Lymphatic Diseases; Mediastinum; Methotrexate; Nitrofurantoin; Penicillamine; Pleural Effusion; Pulmonary Edema; Pulmonary Eosinophilia; Pulmonary Fibrosis; Ritodrine	1985
[Drug-induced hepatic lesions]. Revue medicale de Bruxelles, 1986, Volume: 7, Issue:2 Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Contraceptive Agents; Drug-Related Side Effects and Adverse Reactions; Female; Hemangiosarcoma; Humans; Liver Cirrhosis; Liver Neoplasms; Methotrexate	1986
Drug-induced and iatrogenic infiltrative lung disease. Clinics in chest medicine, 2004, Volume: 25, Issue:3 Topics: Amiodarone; Anti-Arrhythmia Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Iatrogenic Disease; Lung Diseases; Methotrexate; Pneumonia; Pulmonary Alveoli; Pulmonary Edema; Sarcoidosis, Pulmonary	2004
A myriad of pathways to NASH. Clinics in liver disease, 2012, Volume: 16, Issue:3 Topics: Amiodarone; Anti-Retroviral Agents; Bacterial Infections; Cannabis; Diet; Fatty Liver; Genetic Diseases, Inborn; Glucocorticoids; Humans; Hypothyroidism; Insulin Resistance; Intestinal Diseases; Lipid Metabolism; Metabolic Syndrome; Methotrexate; Non-alcoholic Fatty Liver Disease; Occupational Diseases; Perhexiline	2012
Drug-induced hepatic steatosis. Seminars in liver disease, 2014, Volume: 34, Issue:2 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Retroviral Agents; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Hormonal; Drug Evaluation, Preclinical; Fatty Liver; Humans; Immunosuppressive Agents; Lysosomal Storage Diseases; Methotrexate; Mitochondria, Liver; Phospholipids; Tamoxifen; Valproic Acid	2014
Mechanistic review of drug-induced steatohepatitis. Toxicology and applied pharmacology, 2015, Nov-15, Volume: 289, Issue:1 Topics: Amiodarone; Animals; Camptothecin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Irinotecan; Lipid Metabolism; Liver; Methotrexate; Mitochondria, Liver; Organoplatinum Compounds; Oxaliplatin; Perhexiline; Tamoxifen; Tetracycline; Valproic Acid	2015
Animal models of drug-induced pulmonary fibrosis: an overview of molecular mechanisms and characteristics. Cell biology and toxicology, 2022, Volume: 38, Issue:5 Topics: Amiodarone; Animals; Bleomycin; Disease Models, Animal; Idiopathic Pulmonary Fibrosis; Lung; Lung Diseases, Interstitial; Methotrexate	2022

Trials

1 trial(s) available for amiodarone and methotrexate

Article	Year
A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis. Lancet (London, England), 2012, Apr-07, Volume: 379, Issue:9823 Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimanic Agents; Asthma; Community Pharmacy Services; Contraceptives, Oral, Hormonal; Contraindications; Cost-Benefit Analysis; Drug Information Services; Drug Monitoring; Electrolytes; England; Family Practice; Feedback, Psychological; Humans; Immunosuppressive Agents; Lithium Compounds; Medication Errors; Methotrexate; Peptic Ulcer; Pharmacists; Proton Pump Inhibitors; Regression Analysis; Sodium Potassium Chloride Symporter Inhibitors; Urea	2012

Article

Year

A pharmacist-led information technology intervention for medication errors (PINCER): a multicentre, cluster randomised, controlled trial and cost-effectiveness analysis.

Lancet (London, England), 2012, Apr-07, Volume: 379, Issue:9823

Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimanic Agents; Asthma; Community Pharmacy Services; Contraceptives, Oral, Hormonal; Contraindications; Cost-Benefit Analysis; Drug Information Services; Drug Monitoring; Electrolytes; England; Family Practice; Feedback, Psychological; Humans; Immunosuppressive Agents; Lithium Compounds; Medication Errors; Methotrexate; Peptic Ulcer; Pharmacists; Proton Pump Inhibitors; Regression Analysis; Sodium Potassium Chloride Symporter Inhibitors; Urea

2012

Other Studies

27 other study(ies) available for amiodarone and methotrexate

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Drug-induced pulmonary diseases: diagnostic, therapeutic and prognostic aspects. Apropos of 10 personal case reports]. Revue des maladies respiratoires, 1992, Volume: 9, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Aged; Amiodarone; Ampicillin; Antihypertensive Agents; Benzothiadiazines; Bleomycin; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Diuretics; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lung Diseases; Male; Methotrexate; Middle Aged; Phenytoin; Prognosis; Sodium Chloride Symporter Inhibitors; Sulindac; Thiamphenicol	1992
Methotrexate induced skin necrosis: a drug interaction with amiodarone? BMJ (Clinical research ed.), 1989, Oct-14, Volume: 299, Issue:6705 Topics: Aged; Amiodarone; Drug Interactions; Female; Humans; Methotrexate; Necrosis; Skin	1989
Drug-induced interstitial pneumonia. Prescrire international, 2008, Volume: 17, Issue:94 Topics: Amiodarone; Cytotoxins; Drug-Related Side Effects and Adverse Reactions; Humans; Imidazolidines; Lung; Lung Diseases, Interstitial; Methotrexate; Nitrofurantoin; Paraffin; Protein-Tyrosine Kinases; Pulmonary Fibrosis	2008
Amiodarone modulates pharmacokinetics of low-dose methotrexate in rats. Biopharmaceutics & drug disposition, 2008, Volume: 29, Issue:5 Topics: Amiodarone; Animals; Azithromycin; Bile; Drug Antagonism; Infusions, Intravenous; Injections, Intravenous; Kidney; Male; Metabolic Clearance Rate; Methotrexate; Rats; Rats, Wistar	2008
[Toxic effects on the lung: is "pneumonia" caused by drugs?]. MMW Fortschritte der Medizin, 2009, Jun-25, Volume: 151, Issue:26-29 Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Antirheumatic Agents; Bleomycin; Drug-Related Side Effects and Adverse Reactions; Humans; Lung; Lung Diseases; Methotrexate; Nitrofurantoin; Radiography, Thoracic; Risk Factors; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha	2009
Drug-induced photosensitivity. Prescrire international, 2009, Volume: 18, Issue:103 Topics: Aminolevulinic Acid; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Dihematoporphyrin Ether; Diuretics; Doxycycline; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Eczema; Furocoumarins; Hematoporphyrin Photoradiation; Humans; Methotrexate; Onycholysis; Photochemotherapy; Photosensitivity Disorders; Photosensitizing Agents; Porphyrins; Psychotropic Drugs; Quinolines; Skin; Skin Aging; Skin Diseases; Skin Neoplasms; Skin Pigmentation; Sulfonamides; Sunscreening Agents; Tetracycline; Ultraviolet Rays; Urticaria; Verteporfin	2009
Diagnostic and therapeutic challenges. Retina (Philadelphia, Pa.), 2011, Volume: 31, Issue:8 Topics: Adult; Amiodarone; Central Nervous System Diseases; Diagnosis, Differential; Glucocorticoids; Humans; Intraocular Pressure; Male; Methotrexate; Optic Disk; Papilledema; Prednisone; Sarcoidosis; Vasodilator Agents; Vision Disorders; Visual Acuity; Visual Fields	2011
Recurrent ventricular tachycardia in a child with juvenile dermatomyositis - an unusual association. International journal of rheumatic diseases, 2012, Volume: 15, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Dermatomyositis; Fatal Outcome; Humans; Immunosuppressive Agents; Male; Methotrexate; Prednisolone; Recurrence; Tachycardia, Ventricular	2012
Developing a list of high-alert medications for patients with chronic diseases. European journal of internal medicine, 2014, Volume: 25, Issue:10 Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Amiodarone; Analgesics, Opioid; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Cytostatic Agents; Digoxin; Dronedarone; Drug-Related Side Effects and Adverse Reactions; Eplerenone; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Methotrexate; Mineralocorticoid Receptor Antagonists; Platelet Aggregation Inhibitors; Sodium Potassium Chloride Symporter Inhibitors; Spironolactone	2014