amiodarone and losartan

amiodarone has been researched along with losartan in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (60.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Filippatos, G; Laukka, J; Soledad-Conrad, V; Uhal, BD; Wang, R; Zhuang, J1
Dai, Y; Lan, XB; Ling, ZY; Liu, ZC; Luo, KL; Su, L; Wu, JJ; Yang, XY; Yin, YH1
Dai, Y; Dalal, D; Dong, J; Lan, X; Ling, Z; Liu, D; Liu, Z; Luo, K; She, Q; Su, L; Woo, K; Wu, J; Yin, Y1
Li, G; Liu, T1
Gopalam, M; Kanna, B1
Chen, YQ; Lan, XB; Ling, ZY; Liu, D; Liu, ZC; Luo, KL; She, Q; Su, L; Wu, JJ; Yang, XY; Yin, YH; Zrenner, B1
Chen, Y; Du, H; Lan, X; Ling, Z; Liu, Z; She, Q; Su, L; Wu, J; Yin, Y1
Lan, X; Ling, Z; Liu, Z; Su, L; Wu, J; Yang, X; Yin, Y; Zrenner, B1
Al-Hassan, S; Ali, RA; Alomar, H; Arafa, M; Attia, H1

Reviews

1 review(s) available for amiodarone and losartan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for amiodarone and losartan

ArticleYear
[Long-term clinical efficacy of losartan or perindopril combination therapy with low-dose amiodarone in patients with paroxysmal atrial fibrillation].
    Zhonghua xin xue guan bing za zhi, 2006, Volume: 34, Issue:4

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Losartan; Male; Middle Aged; Perindopril; Prospective Studies

2006
Prospective randomized study comparing amiodarone vs. amiodarone plus losartan vs. amiodarone plus perindopril for the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation.
    European heart journal, 2006, Volume: 27, Issue:15

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Drug Therapy, Combination; Female; Heart Atria; Humans; Losartan; Male; Middle Aged; Perindopril; Prospective Studies; Secondary Prevention; Treatment Outcome

2006

Other Studies

17 other study(ies) available for amiodarone and losartan

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists.
    Pharmacology & toxicology, 2003, Volume: 92, Issue:2

    Topics: Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Apoptosis; Captopril; Epithelium; Losartan; Lung; Male; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Wistar; Time Factors

2003
Anti-inflammatory effects of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Potential benefits for the prevention of atrial fibrillation.
    European heart journal, 2006, Volume: 27, Issue:19

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Combinations; Humans; Losartan; Perindopril; Randomized Controlled Trials as Topic

2006
Prospective randomized study comparing amiodarone vs. amiodarone plus losartan vs. amiodarone plus perindopril for the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation.
    European heart journal, 2007, Volume: 28, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therapy, Combination; Humans; Losartan; Perindopril; Prospective Studies; Randomized Controlled Trials as Topic; Secondary Prevention

2007
[Chronic effects on the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation treated with amiodarone, segmental pulmonary vein ablation, or amiodarone plus losartan: a prospective cohort study].
    Zhonghua xin xue guan bing za zhi, 2007, Volume: 35, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Combined Modality Therapy; Follow-Up Studies; Humans; Losartan; Middle Aged; Prospective Studies; Treatment Outcome

2007
The effect of different treatment strategies on left atrial size in patients with lone paroxysmal atrial fibrillation-a prospective cohort study.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2008, Volume: 23, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Chi-Square Distribution; Echocardiography; Female; Heart Atria; Humans; Losartan; Male; Middle Aged; Prospective Studies; Pulmonary Veins; Recurrence; Survival Rate; Treatment Outcome

2008
Catheter ablation vs. amiodarone plus losartan for prevention of atrial fibrillation recurrence in patients with paroxysmal atrial fibrillation.
    European journal of clinical investigation, 2009, Volume: 39, Issue:8

    Topics: Amiodarone; Angiotensin II Type 2 Receptor Blockers; Atrial Fibrillation; Catheter Ablation; Drug Therapy, Combination; Female; Humans; Losartan; Male; Middle Aged; Prospective Studies; Secondary Prevention; Treatment Outcome

2009
The inhibitory mechanisms of losartan and vitamin D on amiodarone-induced lung inflammation in rats: Role of mitogen-activated protein kinases/activator protein-1.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:12

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Interferon-gamma; Losartan; Lung; Male; Mitogen-Activated Protein Kinases; Pneumonia; Rats; Rats, Wistar; Transcription Factor AP-1; Vitamin D

2021