amiodarone has been researched along with kb 130015 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlsson, B; Li, YL; Malm, J; Mellin, C; Nilsson, S; Singh, BN; Temciuc, M | 1 |
| Brandts, B; Carlsson, B; Gendviliene, V; Macianskiene, R; Mubagwa, K; Viappiani, S | 1 |
| Borchard, R; Brandts, B; Dirkmann, D; Gendviliene, V; Macianskiene, R; Meine, M; Mubagwa, K; Prull, M; Trappe, HJ; Van Bracht, M; Wickenbrock, I | 1 |
| Baritussio, A; Bigler, L; Bruttomesso, D; Duner, E; Follath, F; Ha, HR; Pettenazzo, A; Quaglino, D; Realdi, G | 1 |
| Bito, V; Dauwe, D; Mubagwa, K; Sipido, KR; Verdonck, F | 1 |
| Gessner, G; Heinemann, SH; Heller, R; Hoshi, T | 1 |
| Gessner, G; Heinemann, SH; Macianskiene, R; Schönherr, R; Starkus, JG | 1 |
1 review(s) available for amiodarone and kb 130015
| Article | Year |
|---|---|
KB130015, a new amiodarone derivative with multiple effects on cardiac ion channels.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Calcium Channels, L-Type; Ion Channels; Myocardial Contraction; Myocardium; Potassium Channels; Sodium Channels; Stimulation, Chemical | 2003 |
6 other study(ies) available for amiodarone and kb 130015
| Article | Year |
|---|---|
Synthesis and preliminary characterization of a novel antiarrhythmic compound (KB130015) with an improved toxicity profile compared with amiodarone.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Body Weight; Brain; Calcium Channels, L-Type; CHO Cells; Cholesterol; Cricetinae; Guinea Pigs; Heart; Humans; In Vitro Techniques; Liver Function Tests; Radioligand Assay; Rats; Receptors, Thyroid Hormone; Thyroid Function Tests; Transfection | 2002 |
Inhibition of G protein-coupled and ATP-sensitive potassium currents by 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015), an amiodarone derivative.
Topics: Action Potentials; Adenosine Triphosphate; Amiodarone; Animals; Benzofurans; Cells, Cultured; Drug Interactions; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heart Atria; Muscle Cells; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying | 2004 |
Effects of metabolites and analogs of amiodarone on alveolar macrophages: structure-activity relationship.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Cell Survival; Dronedarone; Iodine Radioisotopes; Macrophages, Alveolar; Microscopy, Electron; Pulmonary Surfactant-Associated Protein A; Rabbits; Structure-Activity Relationship; Trachea | 2004 |
The amiodarone derivative KB130015 [2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran] induces an Na+-dependent increase of [Ca2+] in ventricular myocytes.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Calcium; Cell Separation; Female; Heart Ventricles; In Vitro Techniques; Male; Myocytes, Cardiac; Sodium; Sodium-Calcium Exchanger; Swine | 2006 |
The amiodarone derivative 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015) opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle.
Topics: Amiodarone; Animals; Benzofurans; Calcium; Cell Line, Tumor; Humans; Large-Conductance Calcium-Activated Potassium Channels; Muscle Relaxation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Swine; Vasodilation | 2007 |
The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism.
Topics: Amiodarone; Animals; Benzofurans; Cell Line; Electricity; Ether-A-Go-Go Potassium Channels; Female; Humans; Kidney; Oocytes; Patch-Clamp Techniques; Potassium Channels; Xenopus | 2010 |