amiodarone has been researched along with disopyramide in 96 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 63 (65.63) | 18.7374 |
1990's | 11 (11.46) | 18.2507 |
2000's | 14 (14.58) | 29.6817 |
2010's | 8 (8.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Keserü, GM | 1 |
Nagashima, R; Nishikawa, T; Tobita, M | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Jia, L; Sun, H | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Sen, S; Sinha, N | 1 |
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Theisen, K | 1 |
Donaldson, RM | 1 |
Troup, PJ; Zipes, DP | 1 |
Koch-Weser, J | 1 |
Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA | 1 |
Fomina, IG; Iankin, VV | 1 |
Locati, F; Nava, S; Veniani, M; Villani, R; Zoletti, F | 1 |
Korkushko, OV; Shatilo, VB | 1 |
Kurbanov, RD | 1 |
Bacior, B; Dabrowski, A; Fryśna-Dmuchowska, B; Kargul, W; Król, J; Królikowski, Z; Luczak, D; Malczewska, B; Nessler, J; Ostrowska, B | 1 |
Akhdim, H; Kantelip, JP; Magnin, P; Stimmesse, B; Toubin, G | 1 |
Roden, DM | 1 |
Amiel, A; Badouraly, A; Boutaud, P; Demange, J; Gaudeau, B; Guillem, JP; Herpin, D; Tournadre, P | 1 |
Hope, FG; Marshall, RJ; Winslow, E | 1 |
Antiu'fev, VF; Arkhipov, MV | 1 |
James, MA; Jones, JV; Papouchado, P | 1 |
Somberg, J | 1 |
Roden, DM; Siddoway, LA; Woosley, RL | 1 |
Roy, D | 1 |
Belhassen, B; Laniado, S; Pines, A | 1 |
Echt, DS; Roden, DM; Woosley, RL | 1 |
Andersson, KE; Wettrell, G | 1 |
Morganroth, J; Nestico, PF | 2 |
Huang, SK; Marcus, FI | 1 |
Light, RT; Onrot, J; Robertson, D; Robertson, RM; Tantengco, MV | 1 |
Bailey, RJ; Benbow, LJ; Leach, C; Martin, A | 1 |
Elharrar, V; Nakaya, Y; Surawicz, B | 1 |
Chekhov, AM; Gimrikh, EO; Gushchin, IV; Mikhaĭlenko, AI; Popov, SV | 1 |
Chernov, VI; Gimrikh, EO; Gushchin, IV; Volkova, TG | 1 |
Kiiakbaev, GK; Kurbanov, RD | 1 |
James, MA; Papouchado, M; Vann Jones, J | 1 |
Carrasco, HA; Fuenmayor, A; Landaeta, A; López, F; Molina, C; Reynosa, J; Vicuña, AV; Vicuña, N | 1 |
Kushakovskiĭ, MS; Uzilevskaia, RA | 1 |
De Thomatis, M | 1 |
Opie, LH | 1 |
Lawrie, TD | 1 |
DiBianco, R; Fletcher, RD; Gottdiener, JS | 1 |
Attuel, P; Coumel, P; Georgiopoulos, G; Halkidis, H; Leclercq, JF; Maisonblanche, P | 1 |
Reid, PR; Vlay, SC | 1 |
Hillis, WS; Whiting, B | 1 |
Prystowsky, EN | 1 |
Ali, C; Holt, DW; Volans, GN | 1 |
Somberg, JC | 1 |
Lüderitz, B; Manz, M; Steinbeck, G | 2 |
Doherty, JU; Josephson, ME; Kienzle, MG; Williams, PD; Zygmont, D | 1 |
Jahrmärker, H; Theisen, K | 1 |
Aksenova, TN; Andriukova, EI; Doshchitsin, VL; Zakharov, VN; Zhivoderov, VM | 1 |
Mohiuddin, SM; Ross, WB | 1 |
Lüderitz, B | 1 |
Kerr, CR; Levick, CE; Mizgala, HF | 1 |
Rosen, MR; Wit, AL | 1 |
Block, PJ; Winkle, RA | 1 |
Bounhoure, JP; Calazel, J; Cassagneau, B; Fauvel, JM; Marin, T; Massabuau, P; Narula, OS; Puel, J; Tournadre, P | 1 |
Bettini, R; Dal Forno, P; Disertori, M; Furlanello, F; Gramegna, L; Inama, G; Vergara, G | 1 |
Kates, RE | 1 |
Delise, P; Di Pede, F; Piccolo, E; Raviele, A | 1 |
Arlotti, M; Lotto, A; Pagnoni, F | 1 |
Cazzani, E; Garbarini, U; Romano, M | 1 |
Jewitt, DE | 1 |
Cho, YW; Kuemmerle, HP; Singh, BN | 1 |
Heger, JJ; Jackman, WM; Naccarelli, GV; Prystowsky, EN; Rinkenberger, RL; Zipes, DP | 1 |
Harrison, DC; Kates, RE; Keefe, DL | 1 |
Basiez, M; Beaughard, M; Duchene-Marullaz, P; Labrid, C; Leinot, M | 1 |
Benhorin, J; Gottlieb, S; Keren, A; Stern, S; Tzivoni, D | 1 |
Coelho, A; Rosen, KM; Strasberg, B; Welch, WJ | 1 |
Benhorin, J; Gavish, D; Gottlieb, S; Keren, A; Levi, J; Stern, S; Tzivoni, D | 1 |
Chiavarelli, V; Milazzotto, F; Vajola, SF | 1 |
Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C | 1 |
Lüderitz, B; Manz, M | 1 |
Fromm, BS; Lehmann, MH; Makkar, RR; Meissner, MD; Steinman, RT | 1 |
Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R | 1 |
Matsumori, A; Nishio, R; Nose, Y; Ono, K; Sasayama, S | 1 |
Morozova, OI; Pozdniakova, NV; Shevyrev, VA; Tatarchenko, IP | 1 |
Arnal, F; Barel, C; Belkhiria, M; Bui-Xuan, B; Chevalier, P; Descotes, J; Gagnieu, MC; Timour, Q; Tsibiribi, P | 1 |
Mounsey, JP; VerNooy, RA | 1 |
Scharf, C | 1 |
28 review(s) available for amiodarone and disopyramide
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New antiarrhythmic agents: amiodarone, aprindine, disopyramide, ethmozin, mexiletine, tocainide, verapamil.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Disopyramide; Electrophysiology; Humans; Mexiletine; Morpholines; Phenothiazines; Verapamil | 1978 |
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Disopyramide; Drug Evaluation; Humans; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Time Factors; Ventricular Fibrillation | 1978 |
[Comparative characteristics of arrhythmogenic effects of anti-arrhythmia agents].
Topics: Aconitine; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Humans; Moricizine; Phenothiazines; Procainamide; Propranolol | 1991 |
Antiarrhythmic drug therapy. Recent advances and current status.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil | 1985 |
Clinical pharmacology of old and new antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide | 1985 |
Antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide | 1986 |
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide | 1986 |
Cardiovascular drugs. I: Antidysrhythmic drugs.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Disopyramide; Drug Interactions; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Tocainide; Verapamil | 1986 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Antiarrhythmic drug therapy of ventricular arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil | 1986 |
Antiarrhythmic agents for chronic ventricular arrhythmias.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide | 1987 |
Comparison of newer antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Disopyramide; Humans; Mexiletine; Tocainide; Verapamil | 1980 |
Effects of antiarrhythmic agents on cardiac function.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Dogs; Encainide; Hemodynamics; Humans; Myocardial Contraction; Quinidine; Verapamil | 1982 |
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atrial Fibrillation; Benzofurans; Digitalis Glycosides; Disopyramide; Encainide; Female; Humans; Lidocaine; Male; Middle Aged; Procainamide; Quinidine; Tachycardia; Verapamil; Wolff-Parkinson-White Syndrome | 1983 |
Antiarrhythmic drug therapy for sustained ventricular tachycardia.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bethanidine; Calcium Channel Blockers; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Encainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Phenytoin; Piperidines; Procainamide; Quinidine; Tachycardia; Tocainide | 1984 |
[Medical treatment of extrasystole and tachycardia (author's transl)].
Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1980 |
Electropharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil | 1983 |
Hemodynamic effects of antiarrhythmic drugs.
Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide | 1983 |
Metabolites of cardiac antiarrhythmic drugs: their clinical role.
Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Disopyramide; Encainide; Humans; Lidocaine; Piperidines; Procainamide; Quinidine | 1984 |
[Control of recurrent ventricular tachycardia in a case of mitral valve prolapse and arterial hypertension, using the combination of disopyramide and amiodarone].
Topics: Amiodarone; Benzofurans; Disopyramide; Drug Therapy, Combination; Female; Heart Ventricles; Humans; Hypertension; Middle Aged; Mitral Valve Prolapse; Pyridines; Tachycardia | 1982 |
Hemodynamic effects of newer antiarrhythmic drugs.
Topics: Acebutolol; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Atenolol; Benzeneacetamides; Disopyramide; Dogs; Hemodynamics; Humans; Mexiletine; Piperidines; Tocainide; Verapamil | 1980 |
New antiarrhythmic drugs: their place in therapy.
Topics: Action Potentials; Ajmaline; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Tosylate; Disopyramide; Encainide; Hemodynamics; Humans; Kinetics; Moricizine; Morpholines; Phenothiazines; Piperidines; Verapamil | 1981 |
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil | 1993 |
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Bepridil; Cardiovascular Agents; Disopyramide; Female; Humans; Male; Middle Aged; Prenylamine; Procainamide; Quinidine; Risk Factors; Sex; Sotalol; Syncope; Tachycardia, Ventricular; Torsades de Pointes | 1993 |
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; Electric Countershock; Flecainide; Humans; Propafenone; Quinidine; Recurrence; Sotalol | 1993 |
Antiarrhythmic drug therapy of atrial fibrillation.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Flecainide; Humans; Phenethylamines; Sotalol; Sulfonamides | 2004 |
[Atrial flutter and fibrillation].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Calcium Channel Blockers; Catheter Ablation; Clinical Trials as Topic; Disopyramide; Electric Countershock; Electrocardiography; Emergencies; Flecainide; Heart Rate; Humans; Middle Aged; Pacemaker, Artificial; Propafenone; Quinidine; Recurrence; Sotalol; Sulfonamides; Treatment Outcome; Vasodilator Agents | 2005 |
10 trial(s) available for amiodarone and disopyramide
Article | Year |
---|---|
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Disopyramide; Drug Evaluation; Humans; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Time Factors; Ventricular Fibrillation | 1978 |
[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
Topics: Adult; Aged; Aged, 80 and over; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Pre-Excitation Syndromes; Procainamide; Propranolol; Quinidine; Time Factors; Verapamil | 1992 |
[A comparison between amiodarone and disopyramide in a delayed-release formulation in the prevention of recurrences of symptomatic atrial fibrillation].
Topics: Amiodarone; Analysis of Variance; Atrial Fibrillation; Delayed-Action Preparations; Disopyramide; Follow-Up Studies; Humans; Recurrence | 1992 |
[Comparison of the anti-arrhythmic effectiveness of ethacizine, ethmozine, cordarone, mexitil and ritmilen in elderly patients with ventricular extrasystole].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Heart Ventricles; Humans; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Placebos | 1990 |
Combined anti-arrhythmic therapy with class 1 and class 3 drugs.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Humans; Male; Mexiletine; Middle Aged; Randomized Controlled Trials as Topic; Single-Blind Method | 1989 |
Comparison of amiodarone and disopyramide in the control of paroxysmal atrial fibrillation and atrial flutter (interim report).
Topics: Aged; Amiodarone; Atrial Fibrillation; Atrial Flutter; Benzofurans; Disopyramide; Female; Humans; Male; Random Allocation | 1986 |
Effect of low oral doses of disopyramide and amiodarone on ventricular and atrial arrhythmias of chagasic patients with advanced myocardial damage.
Topics: Administration, Oral; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chagas Cardiomyopathy; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Female; Heart Atria; Heart Ventricles; Humans; Male; Middle Aged; Myocardium; Random Allocation | 1985 |
[Trial of the clinical use of Ritmilen].
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Drug Therapy, Combination; Echocardiography; Electrocardiography; Heart Conduction System; Humans; Male; Middle Aged; Recurrence; Sinoatrial Node | 1985 |
[Long-term drug therapy in ventricular cardiac arrhythmias. Is an improvement of the prognosis possible?].
Topics: Adult; Aged; Amiodarone; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Long-Term Care; Mexiletine; Middle Aged; Tachycardia | 1983 |
[Value of provocation tests in the evaluation of the treatment of ventricular tachycardias with amiodarone].
Topics: Adult; Aged; Amiodarone; Benzofurans; Clinical Trials as Topic; Disopyramide; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Male; Middle Aged; Tachycardia; Time Factors | 1984 |
59 other study(ies) available for amiodarone and disopyramide
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Drug therapy of tachyarrhythmias (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1978 |
The treatment of supraventricular arrhythmias.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Digoxin; Disopyramide; Electric Countershock; Humans; Phenytoin; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1979 |
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1978 |
[Effect of amiodarone and disopyramide on the results of electrocardiographic exercise stress testing in patients with coronary disease].
Topics: Amiodarone; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Stress, Physiological | 1990 |
[In vitro study, in perfused rabbit heart, of interaction between two anti-arrhythmia agents: amiodarone and disopyramide].
Topics: Amiodarone; Animals; Disopyramide; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Heart; In Vitro Techniques; Male; Myocardium; Perfusion; Rabbits | 1990 |
Antiarrhythmic drugs. Clinical pharmacology of the old and the new agents.
Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Delayed-Action Preparations; Disopyramide; Heart Arrest; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Resuscitation; Tocainide | 1985 |
[Comparison between amiodarone and disopyramide in the treatment of ventricular extrasystoles].
Topics: Adult; Aged; Amiodarone; Benzofurans; Cardiac Complexes, Premature; Disopyramide; Electrocardiography; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Time Factors | 1986 |
Effects of diet-induced hypokalaemia on the antiarrhythmic and electrophysiological actions of prolonged oral treatment with either amiodarone or disopyramide in the anaesthetised rat.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Diet; Disopyramide; Electrocardiography; Electrophysiology; Hypokalemia; Male; Papillary Muscles; Rats; Rats, Inbred Strains | 1987 |
[Anti-arrhythmic activity of atropine, ritmilen, obsidan and cordarone in patients with ventricular allorhythmia].
Topics: Administration, Oral; Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Atropine; Cardiac Complexes, Premature; Disopyramide; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Propranolol | 1989 |
Failure of corticosteroid therapy to prevent induction of ventricular tachycardia in sarcoidosis.
Topics: Adult; Amiodarone; Cardiac Pacing, Artificial; Cardiomyopathies; Disopyramide; Drug Therapy, Combination; Electrophysiology; Fluocortolone; Humans; Male; Mexiletine; Quinidine; Sarcoidosis; Tachycardia | 1989 |
Orthostatic hypotension: clinical spectrum and approach to treatment.
Topics: Adult; Aged; Amiodarone; Disopyramide; Female; Flecainide; Humans; Hypotension, Orthostatic; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Quinidine; Sympathomimetics; Tocainide | 1986 |
Effect of mexiletine, amiodarone and disopyramide on the excitability and refractoriness of canine cardiac fibers: possible relation to antiarrhythmic drug action and classification.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Female; Heart; In Vitro Techniques; Male; Mexiletine; Neurons; Papillary Muscles; Purkinje Fibers; Refractory Period, Electrophysiological | 1987 |
[A combination of kordaron with ritmilen: its effect on the electrophysiology of the heart and its clinical effectiveness].
Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Disopyramide; Drug Evaluation; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Female; Heart; Humans; Male; Middle Aged; Time Factors | 1988 |
[Combined effects of cordarone and ritmilen on the contractile function of the myocardium after intravenous and oral administration of loading doses].
Topics: Administration, Oral; Adult; Aged; Amiodarone; Depression, Chemical; Disopyramide; Drug Synergism; Drug Therapy, Combination; Female; Heart; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Contraction; Tachycardia, Paroxysmal; Tachycardia, Supraventricular | 1988 |
[Clinico-pharmacological interactions of digoxin with ethmozine, disopyramide and amiodarone].
Topics: Amiodarone; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Disopyramide; Drug Synergism; Drug Therapy, Combination; Humans; Middle Aged; Moricizine; Phenothiazines | 1988 |
Combined therapy with disopyramide and amiodarone: a report of 11 cases.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Disopyramide; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Retrospective Studies | 1986 |
[Medical treatment of disturbances of the heart rhythm].
Topics: Ajmaline; Amiodarone; Arrhythmias, Cardiac; Digoxin; Disopyramide; Humans; Procainamide; Propranolol | 1973 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil | 1980 |
[Effects of anti-arrhythmia agents on heart rate. Significance and importance].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lidocaine; Propafenone; Propiophenones; Quinidine; Verapamil | 1981 |
Ventricular ectopy: etiology, evaluation, and therapy.
Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Echocardiography; Electric Stimulation; Humans; Ischemia; Lidocaine; Myocardial Infarction; Nitrates; Pacemaker, Artificial; Phenytoin; Procainamide; Radionuclide Imaging; Risk | 1982 |
Antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil | 1983 |
Management of cardiac drug overdose.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Disopyramide; Humans; Phenytoin; Poison Control Centers; Verapamil | 1984 |
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil | 1984 |
[Sudden heart death in ventricular heart rhythm disorders: possibilities and limits of long-term therapy].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden; Disopyramide; Germany, West; Humans; Mexiletine; Risk; Time Factors; Ventricular Fibrillation | 1984 |
[Anti-arrhythmic effectiveness of ethmozine, cordaron and rhythmodan in treating ischemic heart disease].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzofurans; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Drug Evaluation; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Moricizine; Morpholines; Phenothiazines; Pyridines; Tachycardia | 1981 |
Antiarrhythmic therapy: new additions and future expectations.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Bretylium Tosylate; Disopyramide; Encainide; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil | 1983 |
[Drug therapy of arrhythmia in coronary cardiopathy].
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Tachycardia; Tocainide | 1983 |
Failure to pace following high dose antiarrhythmic therapy--reversal with isoproterenol.
Topics: Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Drug Therapy, Combination; Electrocardiography; Humans; Isoproterenol; Pacemaker, Artificial; Phenytoin; Procainamide; Tachycardia | 1984 |
Worsening of arrhythmias during pharmacological treatment.
Topics: Adolescent; Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Child; Disopyramide; Female; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Nadolol; Piperidines; Propafenone; Propanolamines; Propiophenones; Tocainide | 1984 |
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Pindolol; Propafenone; Propiophenones; Tachycardia; Ventricular Fibrillation | 1984 |
[Pharmacological treatment of supraventricular hyperkinetic arrhythmia in sinus node disease: an alternative to electric treatment].
Topics: Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Bunaftine; Disopyramide; Female; Humans; Infusions, Parenteral; Male; Middle Aged | 1983 |
Clinical pharmacology of antiarrhythmic drugs: a review and overview, part II.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Propranolol; Tocainide | 1981 |
Drug conversion of nonsustained ventricular tachycardia to sustained ventricular tachycardia during serial electrophysiologic studies: identification of drugs that exacerbate tachycardia and potential mechanisms.
Topics: Adult; Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Cardiac Catheterization; Disopyramide; Electric Stimulation; Encainide; Female; Humans; Male; Middle Aged; Quaternary Ammonium Compounds; Tachycardia | 1982 |
Comparative antidysrhythmic profiles of bepridil, amiodarone and disopyramide in the guinea-pig and dog.
Topics: Aconitine; Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Bepridil; Disopyramide; Dogs; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Injections, Intraventricular; Male; Pyridines; Pyrrolidines; Ventricular Fibrillation | 1981 |
Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.
Topics: Adult; Amiodarone; Atrial Fibrillation; Benzofurans; Disopyramide; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Ventricles; Humans; Prajmaline; Pyridines; Quinidine; Tachycardia | 1982 |
Sustained macroreentrant ventricular tachycardia.
Topics: Aged; Amiodarone; Disopyramide; Electrocardiography; Heart Conduction System; Humans; Male; Procainamide; Quinidine; Recurrence; Tachycardia | 1982 |
Etiology, warning signs and therapy of torsade de pointes. A study of 10 patients.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Time Factors | 1981 |
[Pharmacological therapy and prevention of recurrent ventricular tachycardia].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Bunaftine; Disopyramide; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia | 1981 |
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect.
Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil | 1995 |
Amiodarone inhibits production of tumor necrosis factor-alpha by human mononuclear cells: a possible mechanism for its effect in heart failure.
Topics: Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Heart Failure; Humans; Interleukin-1; Interleukin-6; Lidocaine; Monocytes; Osmolar Concentration; Quinidine; Tumor Necrosis Factor-alpha | 1997 |
[Anti-arrhythmic therapy: diagnostic possibilities of signal-averaged electrocardiography and heart rate variability].
Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Data Interpretation, Statistical; Disopyramide; Electrocardiography; Electrocardiography, Ambulatory; Female; Heart; Heart Rate; Humans; Male; Middle Aged; Phenothiazines; Sotalol | 2003 |
Ropivacaine combined with various anti-arrhythmic drugs results in mild alterations in myocardial contractility in pigs.
Topics: Amides; Amiodarone; Analysis of Variance; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Disopyramide; Drug Interactions; Heart Rate; Hemodynamics; Myocardial Contraction; Prospective Studies; Random Allocation; Ropivacaine; Swine | 2003 |
Atrial fibrillation: rate control often better than rhythm control.
Topics: Adult; Aged; Amiodarone; Anticoagulants; Arrhythmia, Sinus; Atrial Fibrillation; Canada; Disopyramide; Electric Countershock; Flecainide; Heart Rate; Humans; Netherlands; Platelet Aggregation Inhibitors; Propafenone; Quinidine; Sotalol; United States | 2004 |