amiodarone has been researched along with cyclosporine in 40 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 7 (17.50) | 18.2507 |
2000's | 12 (30.00) | 29.6817 |
2010's | 21 (52.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Biocine, B; Graham, T; Kendall, S; Large, S; Mamprin, F; Mullins, P; Schofield, P; Wallwork, J | 1 |
Boesch, D; Loor, F; Pourtier-Manzanedo, A | 1 |
Patterson, FK; Wigler, PW | 1 |
de Vries, EG; Meersma, GJ; Mesander, G; Mulder, NH; Timmer-Bosscha, H; van der Graaf, WT; Vellenga, E | 1 |
Abdul-Haqq, AJ; Chitwood, KK; Heim-Duthoy, KL | 1 |
Frenk, E; Krasovec, M; Ricci, C | 1 |
Goebels, R; Keyser, A; Lehle, K; Merk, J; Preuner, JG; Rupprecht, L | 1 |
Landwojtowicz, E; Seelig, A | 1 |
Dobrev, D; Grossmann, M; Himmel, HM; Ravens, U | 1 |
Bigler, L; Follath, F; Ha, HR; Kozlik, P; Stieger, B | 1 |
Barbaro, M; Catania, S; Costa, C; Germanò, MP; Silvari, V | 1 |
Serón, D | 1 |
Azarpira, N; Baghban, M; Jamshidzadeh, A; Mohammadi Bardbori, A; Niknahad, H | 1 |
Brocks, DR; Kanduru, SV; Lavasanifar, A; Somayaji, V | 1 |
Pereira, LM | 1 |
Bouwman, FG; Kleinjans, JC; Mariman, EC; Noben, JP; Renes, J; van Delft, JH; Van Summeren, A | 1 |
Jaeschke, H; McGill, MR; Ramachandran, A | 1 |
Drafts, BC; Dubose, TD; Sutton, BJ; Thohan, V | 1 |
Bouwman, FG; Kleinjans, JC; Lizarraga, D; Mariman, EC; Noben, JP; Renes, J; van Delft, JH; Van Summeren, A | 1 |
Chibout, SD; Germano, D; Pognan, F; Uteng, M; Wolf, A | 1 |
Driessen, M; Kienhuis, AS; Pennings, JL; van der Ven, LT; Vitins, AP; Water, Bv | 1 |
Brooks, P; Morris-Smith, B; Ogbourne, SM; Wallis, M; Woodward, Z | 1 |
1 review(s) available for amiodarone and cyclosporine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
39 other study(ies) available for amiodarone and cyclosporine
Article | Year |
---|---|
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Amiodarone-cyclosporine interaction in cardiac transplantation.
Topics: Amiodarone; Cyclosporine; Drug Interactions; Heart Transplantation; Humans; Postoperative Care | 1992 |
FK-506 (fujimycin) reverses the multidrug resistance of tumor cells in vitro.
Topics: Amiodarone; Animals; Antibiotics, Antineoplastic; Cyclosporine; Doxorubicin; Drug Resistance; Leukemia P388; Tacrolimus; Tumor Cells, Cultured; Verapamil; Vincristine | 1991 |
Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Drug Resistance; Humans; Leukemia; Membrane Glycoproteins; Propranolol; Propylamines; Quinidine; Quinine; Rhodamine 123; Rhodamines; Stereoisomerism; Tumor Cells, Cultured | 1994 |
Effects of amiodarone, cyclosporin A, and PSC 833 on the cytotoxicity of mitoxantrone, doxorubicin, and vincristine in non-P-glycoprotein human small cell lung cancer cell lines.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cyclosporine; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Lung Neoplasms; Mitoxantrone; Tumor Cells, Cultured; Vincristine | 1994 |
Cyclosporine-amiodarone interaction.
Topics: Aged; Amiodarone; Cyclosporine; Drug Interactions; Drug Monitoring; Female; Humans; Kidney Transplantation; Tachycardia, Ventricular | 1993 |
[Amiodarone induced iododerma treated by cyclosporine].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cyclosporine; Debridement; Facial Dermatoses; Humans; Immunosuppressive Agents; Iodides; Male; Skin Ulcer | 1997 |
Development of severe adverse effects after discontinuing amiodarone therapy in human heart transplant recipients.
Topics: Amiodarone; Anti-Arrhythmia Agents; Bilirubin; Cyclosporine; Drug Interactions; Half-Life; Heart Transplantation; Humans; Immunosuppressive Agents; Neutrophils | 1998 |
Structure-activity relationship of P-glycoprotein substrates and modifiers.
Topics: Adenosine Triphosphatases; Amiodarone; Amitriptyline; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Daunorubicin; Diltiazem; Kinetics; Micelles; Progesterone; Propranolol; Structure-Activity Relationship; Verapamil; Vinblastine | 2000 |
N-desethylamiodarone modulates intracellular calcium concentration in endothelial cells.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Aorta; Calcium; Calcium-Transporting ATPases; Cattle; Cell Division; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Space; Homeostasis; Kinetics; Mitochondria; Thapsigargin; Vasodilator Agents | 2000 |
Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone.
Topics: Amiodarone; Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ketoconazole; Kinetics; Microsomes, Liver; Midazolam; Models, Chemical; Oxidoreductases, N-Demethylating; Protein Isoforms; Quinidine; Rabbits; Rifampin; Time Factors | 2001 |
Cytotoxicity evaluation after coexposure to perchloroethylene and selected peroxidant drugs in rat hepatocytes.
Topics: Amino Acid Oxidoreductases; Amiodarone; Animals; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Forecasting; Formazans; Hepatocytes; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Occupational Exposure; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase; Tetrachloroethylene; Tetrazolium Salts; Thiobarbituric Acid Reactive Substances; Tocopherols; Valproic Acid | 2004 |
Management of cardiovascular risk in patients receiving calcineurin inhibitors--a case report.
Topics: Acenocoumarol; Amiodarone; Angioplasty; Calcineurin Inhibitors; Carbazoles; Carvedilol; Cyclosporine; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Immunosuppressive Agents; Indoles; Kidney Transplantation; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Postoperative Complications; Pravastatin; Prednisone; Propanolamines; Risk Factors; Tacrolimus; Treatment Outcome | 2006 |
Effects of tomato extract on oxidative stress induced toxicity in different organs of rats.
Topics: Acetaminophen; Amiodarone; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Cyclosporine; Glutathione; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Lung Diseases; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Solanum lycopersicum | 2008 |
An analytical method for cyclosporine using liquid chromatography-mass spectrometry.
Topics: Amiodarone; Animals; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Cyclosporine; Half-Life; Immunosuppressive Agents; Indicators and Reagents; Male; Mass Spectrometry; Plasma; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results | 2010 |
Fractal pharmacokinetics.
Topics: Algorithms; Amiodarone; Animals; Calcium; Computer Simulation; Cyclosporine; Diffusion; Fractals; Humans; Kinetics; Models, Biological; Pharmacokinetics | 2010 |
Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.
Topics: Acetaminophen; Amiodarone; Blotting, Western; Cell Survival; Chemical and Drug Induced Liver Injury; Cluster Analysis; Cyclosporine; Drug-Related Side Effects and Adverse Reactions; Electrophoresis, Gel, Two-Dimensional; Hep G2 Cells; Humans; Pharmaceutical Preparations; Protein Biosynthesis; Protein Processing, Post-Translational; Proteins; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2011 |
Pathophysiological relevance of proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.
Topics: Acetaminophen; Amiodarone; Chemical and Drug Induced Liver Injury; Cyclosporine; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Proteomics | 2011 |
Incessant ventricular tachycardia and cardiogenic shock: a common presentation of an uncommon diagnosis.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Blood Chemical Analysis; Cardiac Catheterization; Coronary Angiography; Cyclosporine; Diagnosis, Differential; Electrocardiography; Giant Cells; Heart; Heart Ventricles; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Myocarditis; Myocardium; North Carolina; Prednisone; Shock, Cardiogenic; Tachycardia, Ventricular; Treatment Outcome; Ventricular Dysfunction, Left | 2011 |
Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin a as model compounds: an omics-guided approach.
Topics: Acetaminophen; Amiodarone; Animals; Cell Line; Cluster Analysis; Cyclosporine; Gene Expression Profiling; Gene Expression Regulation; Genomics; Hep G2 Cells; Hepatocytes; Humans; Male; Mice; Primary Cell Culture; Proteome; Proteomics | 2013 |
Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment.
Topics: Amiodarone; Animals; Cells, Cultured; Chlorpromazine; Chromans; Culture Techniques; Cyclosporine; Dopamine Antagonists; Gene Expression Regulation; Hepatocytes; Hypoglycemic Agents; Immunosuppressive Agents; Male; Potassium Channel Blockers; Rats; Rats, Wistar; Thiazolidinediones; Troglitazone | 2015 |
A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen.
Topics: Acetaminophen; Amiodarone; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Cyclosporine; Embryo, Nonmammalian; Gene Expression; Hepatocytes; Humans; Immunosuppressive Agents; In Vitro Techniques; Mice; Mice, Inbred C57BL; Rats; Transcriptome; Zebrafish | 2015 |
Adsorption and Leachable Contamination of Flucloxacillin, Cyclosporin and Amiodarone Following Delivery Through an Intravenous Administration Set.
Topics: Administration, Intravenous; Adsorption; Amiodarone; Cyclosporine; Drug Contamination; Floxacillin | 2018 |