amiodarone and caffeine

amiodarone has been researched along with caffeine in 32 studies

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (15.63)	18.2507
2000's	10 (31.25)	29.6817
2010's	17 (53.13)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Sen, S; Sinha, N	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brik, H; Rotmensch, HH; Shainberg, A; Weinstein, L	1
Aomine, M	1
Dukhanin, AS; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI; Sergeev, PV	1
Aebi, Y; Thormann, W; Zhang, CX	1
Courchesne, WE; Ozturk, S	1
Manoach, M; Shainberg, A; Shneyvays, V; Tribulova, N; Zinman, T	1
Knudsen, K; Rudolph, T	1
Biedroń, W; Ciszowski, K; Gomólka, E	1
Bortot, A; Boscolo, A; Geraldini, F; Longo, L; Muraro, L; Paoli, A	1
Gerloff, K; Horvat, T; Mennecozzi, M; Paini, A; Palosaari, T; Sala Benito, JV; Worth, A	1
Louisse, J; Macko, P; Paini, A; Sala Benito, JV; Worth, AP	1

Reviews

1 review(s) available for amiodarone and caffeine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

31 other study(ies) available for amiodarone and caffeine

Article	Year
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharmaceutical research, 1999, Volume: 16, Issue:3 Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Characterization of sarcoplasmic reticulum in skinned heart muscle cultures. Journal of cellular physiology, 1991, Volume: 148, Issue:1 Topics: Amiodarone; Animals; Caffeine; Calcimycin; Calcium; Cells, Cultured; Myocardium; Saponins; Sarcoplasmic Reticulum; Temperature; Time Factors; Trifluoperazine	1991
The inhibitory actions of amiodarone on rested-state contraction in isolated guinea-pig ventricular muscle. General pharmacology, 1990, Volume: 21, Issue:5 Topics: Amiodarone; Animals; Caffeine; Female; Guinea Pigs; In Vitro Techniques; Male; Microelectrodes; Myocardial Contraction; Papillary Muscles; Verapamil	1990
[Mechanism of action of befol on calcium metabolism in cardiomyocytes using the fluorescent probe fura-2]. Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 121, Issue:3 Topics: Amiodarone; Animals; Benzamides; Caffeine; Calcium; Fura-2; Heart; In Vitro Techniques; Ion Transport; Morpholines; Myocardium; Rats; Verapamil	1996
Microassay of amiodarone and desethylamiodarone in serum by capillary electrophoresis with head-column field-amplified sample stacking. Clinical chemistry, 1996, Volume: 42, Issue:11 Topics: Amiodarone; Caffeine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Microchemistry; Reproducibility of Results; Theophylline	1996
Amiodarone induces a caffeine-inhibited, MID1-depedent rise in free cytoplasmic calcium in Saccharomyces cerevisiae. Molecular microbiology, 2003, Volume: 47, Issue:1 Topics: Amiodarone; Caffeine; Calcium; Calcium Channels; Cytosol; Drug Interactions; Ion Channel Gating; Membrane Glycoproteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2003
Acute, nongenomic effect of thyroid hormones in preventing calcium overload in newborn rat cardiocytes. Journal of cellular physiology, 2006, Volume: 207, Issue:1 Topics: Amiodarone; Angiotensin II; Animals; Animals, Newborn; Caffeine; Calcium; Calcium Signaling; Calcium-Binding Proteins; Cell Hypoxia; Choline; Cytoskeleton; Dose-Response Relationship, Drug; Isoproterenol; Isoquinolines; L-Lactate Dehydrogenase; Myocytes, Cardiac; Phosphorylation; Protein Kinase Inhibitors; Rats; Sarcoplasmic Reticulum; Sulfonamides; Thapsigargin; Thyroid Hormones; Thyroxine; Triiodothyronine	2006
A case of fatal caffeine poisoning. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Caffeine; Cardiopulmonary Resuscitation; Central Nervous System Stimulants; Electric Countershock; Electrocardiography; Fatal Outcome; Female; Heart Arrest; Humans; Hypokalemia; Hypoxia, Brain; Pneumonia; Ventricular Fibrillation; Water-Electrolyte Imbalance; Young Adult	2010
Acute caffeine poisoning resulting in atrial fibrillation after guarana extract overdose. Przeglad lekarski, 2014, Volume: 71, Issue:9 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Caffeine; Drug Overdose; Echocardiography; Electrolytes; Humans; Hypertrophy, Left Ventricular; Male; Paullinia; Plant Extracts	2014
Intralipid in acute caffeine intoxication: a case report. Journal of anesthesia, 2016, Volume: 30, Issue:5 Topics: Advanced Cardiac Life Support; Amiodarone; Antidotes; Caffeine; Drug Overdose; Emulsions; Epinephrine; Humans; Male; Phospholipids; Shock; Soybean Oil; Tachycardia; Vasoconstrictor Agents; Vasodilator Agents; Ventricular Fibrillation; Young Adult	2016
Practical use of the Virtual Cell Based Assay: Simulation of repeated exposure experiments in liver cell lines. Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 45, Issue:Pt 2 Topics: Amiodarone; Animal Testing Alternatives; Caffeine; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Computer Simulation; Humans; Liver; Models, Biological	2017
Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes. Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 45, Issue:Pt 2 Topics: Amiodarone; Animal Testing Alternatives; Caffeine; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cell Survival; Cells, Cultured; Computer Simulation; Hepatocytes; Humans; Membrane Potential, Mitochondrial; Mitochondria; Models, Biological; Myocytes, Cardiac	2017