amiodarone and acetylcysteine

amiodarone has been researched along with acetylcysteine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's7 (58.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bandyopadhyay, S; Klaunig, JE; Ruch, RJ; Somani, P1
Brien, JF; Leeder, RG; Massey, TE1
Davis, EM; Hilleman, DE; Packard, KA1
Durukan, AB; Durukan, E; Erdem, B; Gurbuz, HA; Gurpinar, A; Karaduman, T; Sevim, H; Yorgancioglu, C1
Dave, KP; Hummel, JP; Mudalel, ML; Solga, SF1
Amar, D; Chung, MK; Desiderio, D; Fischer, GW; Isbell, JM; Jones, DR; Meyers, BF; Milne, GL; Molena, D; Park, BJ; Pedoto, A; Roistacher, N; Rusch, VW; Tan, KS; Zhang, H1

Reviews

2 review(s) available for amiodarone and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacologic prophylaxis of postoperative atrial fibrillation in patients undergoing cardiac surgery: beyond beta-blockers.
    Pharmacotherapy, 2010, Volume: 30, Issue:7

    Topics: Acetylcysteine; Adrenergic beta-Antagonists; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial Fibrillation; Calcium Channel Blockers; Cardiac Surgical Procedures; Digoxin; Fatty Acids, Omega-3; Hospital Costs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Postoperative Period; Sotalol

2010

Trials

1 trial(s) available for amiodarone and acetylcysteine

ArticleYear
Amiodarone with or without N-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial.
    Anesthesiology, 2022, 06-01, Volume: 136, Issue:6

    Topics: Acetylcysteine; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Double-Blind Method; Humans; Inflammation; Postoperative Complications; Thoracic Surgery

2022

Other Studies

9 other study(ies) available for amiodarone and acetylcysteine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Evaluation of amiodarone free radical toxicity in rat hepatocytes.
    Toxicology letters, 1991, Volume: 56, Issue:1-2

    Topics: Acetylcysteine; Amiodarone; Animals; Antioxidants; Butylated Hydroxytoluene; Catalase; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Free Radicals; Kinetics; Liver; Male; Phenylenediamines; Rats; Rats, Inbred Strains; Superoxide Dismutase; Time Factors

1991
Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:6

    Topics: Acetylcysteine; Allyl Compounds; Amiodarone; Animals; Antioxidants; Butylated Hydroxyanisole; Cricetinae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Lung; Lung Diseases; Male; Mesocricetus; Oxidative Stress; Pulmonary Fibrosis; Sulfides; Superoxide Dismutase

1994
May toxicity of amiodarone be prevented by antioxidants? A cell-culture study.
    Journal of cardiothoracic surgery, 2012, Jun-28, Volume: 7

    Topics: Acetylcysteine; Amiodarone; Animals; Antioxidants; Ascorbic Acid; Cell Line, Transformed; Cell Survival; Drug Interactions; Fibroblasts; Mice; Oxidative Stress

2012
N-acetylcysteine treats intravenous amiodarone induced liver injury.
    World journal of gastroenterology, 2015, Mar-07, Volume: 21, Issue:9

    Topics: Acetylcysteine; Aged; Amiodarone; Anti-Arrhythmia Agents; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Liver; Liver Function Tests; Oxidative Stress; Time Factors; Treatment Outcome

2015