aminotadalafil and formic-acid

We developed a method for the identification of 18 illegal adulterants in dietary supplements for erectile dysfunction by using high-performance liquid chromatography-mass spectrometry. The separation was achieved on a Cosmosil 3C18-EB column. The mobile phase consisted of 0.1% formic acid solution and 0.1% formic acid in acetonitrile, with gradient elution at a flow rate of 0.15 mL/min. The proposed method may be useful for the identification of illegal adulterants and for quality control of dietary supplements.

Topics: Acetonitriles; Benzodioxoles; Carbolines; Chromatography, High Pressure Liquid; Dietary Supplements; Food Contamination; Formates; Mass Spectrometry; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Quality Control; Sildenafil Citrate; Solutions; Sulfones; Tadalafil; Urological Agents; Vasodilator Agents