Page last updated: 2024-08-17

aminopyrine and warfarin

aminopyrine has been researched along with warfarin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's4 (14.81)18.2507
2000's2 (7.41)29.6817
2010's6 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caron, G; Ermondi, G1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Johnson, EF; Muller-Eberhard, U1
Moilanen, ML; Pelkonen, O1
Ackermann, E1
Van der Zee, J; Van Steveninck, J; Williams, M1
Humphries, TJ1
Nakanishi, S; Nishiguchi, K; Serasinghe, P; Yamazaki, H1
Elias, E; Iqbal, S; Vickers, C1
Heubel, F; Netter, KJ; Vesell, ES1
du Souich, P; Kobusch, AB; Plaa, GL1
Murase, T; Nakanishi, S; Okuno, H; Sameshima, Y; Shiozaki, Y1
Citti, L; Gervasi, PG; Longo, V1
Cederbaum, AI; Feierman, DE; Krikun, G1
Christensen, F; Wissing, F1
Deckert, FW; Remmer, HK1
Feuer, G; Lumb, G; Moddel, G; Sosa-Lucero, JC1
Noshiro, M; Omura, T1
GRUNDNER, HG; HARTERT, H; SCHULT, A1
BURNS, JJ; CONNEY, AH1
GAROFALO, E1

Reviews

2 review(s) available for aminopyrine and warfarin

ArticleYear
Clinical implications of drug interactions with the cytochrome P-450 enzyme system associated with omeprazole.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:12

    Topics: Aminopyrine; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Omeprazole; Phenytoin; Propranolol; Theophylline; Warfarin

1991
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM.
    Seminars in hematology, 1964, Volume: 1

    Topics: Aminopyrine; Chloramphenicol; Coumarins; Dicumarol; Humans; Metabolism; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenobarbital; Phenylbutazone

1964

Other Studies

25 other study(ies) available for aminopyrine and warfarin

ArticleYear
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Resolution of two forms of cytochrome P-450 from liver microsomes of rabbit treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    The Journal of biological chemistry, 1977, May-10, Volume: 252, Issue:9

    Topics: Acetanilides; Aminopyrine; Animals; Antibody Formation; Benzopyrenes; Catalysis; Coumarins; Cross Reactions; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Dioxins; Hydroxylation; Kinetics; Liver; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Polychlorinated Dibenzodioxins; Rabbits; Structure-Activity Relationship

1977
The specificity and multiplicity of human placental xenobiotic-metabolizing monooxygenase system studied by potential substrates, inhibitors and gel electrophoresis.
    Medical biology, 1979, Volume: 57, Issue:5

    Topics: Aldrin; Aminopyrine; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Biotransformation; Biphenyl Compounds; Coumarins; Electrophoresis, Polyacrylamide Gel; Female; Flavonoids; Humans; Microsomes; Placenta; Pregnancy; Proadifen; Smoking

1979
[Pharmacokinetics in liver cirrhosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jan-01, Volume: 32, Issue:1

    Topics: Aminopyrine; Biotransformation; Chloramphenicol; Coumarins; Half-Life; Humans; Kinetics; Liver Cirrhosis; Pharmaceutical Preparations; Phenylbutazone; Salicylates; Tolbutamide

1977
Toxic dark effects of protoporphyrin on the cytochrome P-450 system in rat liver microsomes.
    The Biochemical journal, 1992, Nov-15, Volume: 288 ( Pt 1)

    Topics: Aminopyrine; Animals; Coumarins; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Female; Kinetics; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protoporphyrins; Rats; Rats, Sprague-Dawley

1992
Differential localization of microsomal mixed function oxidase activity in periportal and perivenous hepatocytes isolated from rat liver.
    The International journal of biochemistry, 1990, Volume: 22, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Coumarins; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Male; Microsomes, Liver; NADH Dehydrogenase; Oxidoreductases Acting on CH-NH Group Donors; Rats; Rats, Inbred Strains

1990
Drug metabolism in end-stage liver disease. In vitro activities of some phase I and phase II enzymes.
    Journal of hepatology, 1990, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aminopyrine; Child; Coumarins; Cytochrome P-450 Enzyme System; Estrone; Female; Humans; Lithocholic Acid; Liver Diseases; Liver Function Tests; Male; Middle Aged; Oxazines; Pharmaceutical Preparations; Sulfotransferases

1990
Brief maternal deprivation of rats reduces hepatic mixed function oxidase activities.
    Life sciences, 1989, Volume: 45, Issue:19

    Topics: Aminopyrine; Animals; Benzphetamine; Biotransformation; Body Weight; Coumarins; Enzyme Induction; Female; Handling, Psychological; Male; Maternal Deprivation; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains

1989
Effects of acetone and methyl n-butyl ketone on hepatic mixed-function oxidase.
    Biochemical pharmacology, 1989, Oct-15, Volume: 38, Issue:20

    Topics: Acetone; Aminopyrine; Aniline Compounds; Animals; Carbon Tetrachloride; Coumarins; Cytochrome P-450 Enzyme System; Isoenzymes; Ketones; Liver; Male; Methyl n-Butyl Ketone; Rats; Rats, Inbred Strains

1989
Effect of malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) on drug metabolizing activity in rat liver microsomes.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:3

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzo(a)pyrene; Coumarins; Cytochromes; Male; Malonates; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Rats; Rats, Inbred Strains

1987
Biotransformation enzymes in nasal mucosa and liver of Sprague-Dawley rats.
    Toxicology letters, 1988, Volume: 44, Issue:3

    Topics: Aminopyrine; Animals; Biotransformation; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Hempa; Microsomes; Microsomes, Liver; Nasal Mucosa; Oxazines; Rats; Rats, Inbred Strains

1988
Rat liver microsomal induction of the oxidation of drugs and alcohols, and sodium dodecyl sulfate-gel profiles after in vivo treatment with pyrazole or 4-methylpyrazole.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Butanols; Coumarins; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethanol; Fomepizole; Isoenzymes; Kinetics; Male; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Pharmaceutical Preparations; Pyrazoles; Rats; Rats, Inbred Strains; Sodium Dodecyl Sulfate; Stereoisomerism

1986
Inhibition of microsomal drug-metabolizing enzymes from rat liver by various 4-hydroxycoumarin derivatives.
    Biochemical pharmacology, 1972, Apr-01, Volume: 21, Issue:7

    Topics: Acenocoumarol; Aminopyrine; Aniline Compounds; Animals; Anisoles; Benzyl Compounds; Coumarins; Cytochromes; Dealkylation; Dicumarol; Ethyl Biscoumacetate; In Vitro Techniques; Indophenol; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitro Compounds; Oxidoreductases; Phenols; Rats; Rats, Inbred Strains; Spectrophotometry; Warfarin

1972
In vitro inhibition of rat and human liver microsomal enzymes by 4-hydroxycoumarin anticoagulants and related compounds.
    Chemico-biological interactions, 1972, Volume: 5, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Anticoagulants; Binding Sites; Coumarins; Humans; Kinetics; Methylation; Microsomes, Liver; Oxidoreductases; Rats; Salicylates; Species Specificity; Spectrum Analysis; Warfarin

1972
Failure of various drugs to induce drug-metabolizing enzymes in extrahepatic tissues of the rat.
    Toxicology and applied pharmacology, 1971, Volume: 19, Issue:4

    Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Brain; Chlorpromazine; Coumarins; Enzyme Induction; Female; Hexobarbital; Hydrochlorothiazide; Intestines; Kidney; Liver; Male; Methylcholanthrene; Metyrapone; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors

1971
Microsomal monooxygenase system in frog livers.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1984, Volume: 77, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzo(a)pyrene; Benzopyrenes; Bufonidae; Coumarins; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Potassium Cyanide; Rana catesbeiana; Ranidae; Rats; Xenopus laevis

1984
[Research on a pyramidon derivative without delayed action on a simultaneously administered anticoagulant coumarin derivative].
    Die Medizinische Welt, 1962, Feb-10, Volume: 6

    Topics: Aminopyrine; Anticoagulants; Blood Coagulation; Coumarins; Delayed-Action Preparations; Research

1962
[Clinical tests in pediatrics of the effect of a new compound with antirheumatic and antipyretic action].
    Minerva pediatrica, 1955, Apr-14, Volume: 7, Issue:15

    Topics: Aminopyrine; Antipyretics; Child; Coumarins; Humans; Pediatrics; Respiratory System; Respiratory Tract Diseases; Tonsillitis

1955