Page last updated: 2024-08-17

aminopyrine and ranitidine

aminopyrine has been researched along with ranitidine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199012 (44.44)18.7374
1990's7 (25.93)18.2507
2000's3 (11.11)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Akamatsu, M1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Carrasco, M; del Villar, E; Gaule, C; Vega, P1
Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L1
Fryklund, J; Wallmark, B1
Miederer, S; Ruoff, HJ; Schepp, W; Schusdziarra, V1
Hajos, ZG; Press, JB; Sanfilippo, PJ; Scott, CK; Shriver, DA; Urbanski, M1
Miederer, SE; Ruoff, HJ; Schepp, W; Wulfhekel, U1
Miederer, SE; Ruoff, HJ; Schepp, W2
Dembiński, A; Drozdowicz, D; Gregory, H; Konturek, SJ; Warzecha, Z1
Anthony, L; Combs, G; Combs, GL; Hande, K; Swingle, R1
Anthony, LB; Brenner, DE; Collins, JC; Halter, S; Hande, KR; Harris, NL1
Bell, GD; Henry, DA; Kitchingman, G; Langman, MJ; Macdonald, IA1
Avant, GR; Mitchell, MC; Patwardhan, RV; Schenker, S; Speeg, KV1
Henry, DA; Langman, MJ1
Pendleton, RG; Shepherd-Rose, AJ1
Cabero, JL; Li, ZQ; Mårdh, S; Nilsson, BO1
Beales, IL; Calam, J1
Arebi, N; Beales, IL; Bliss, P; Calam, J; Edwards, J; Healey, ZV1
Arai, H; Inoie, M; Marubuchi, S1
Bakke, I; Cui, G; Munkvold, B; Sandvik, AK; Waldum, HL1

Trials

1 trial(s) available for aminopyrine and ranitidine

ArticleYear
Cimetidine and ranitidine: comparison of effects on hepatic drug metabolism.
    British medical journal, 1980, Sep-20, Volume: 281, Issue:6243

    Topics: Aminopyrine; Antipyrine; Cimetidine; Furans; Guanidines; Half-Life; Histamine H2 Antagonists; Humans; Microsomes, Liver; Ranitidine

1980

Other Studies

26 other study(ies) available for aminopyrine and ranitidine

ArticleYear
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
[H2 antagonists as inhibitors of cytochrome P-450 in rat liver: in vitro and in vivo effects].
    Revista medica de Chile, 1992, Volume: 120, Issue:5

    Topics: Administration, Oral; Aminopyrine; Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Induction; Famotidine; Hemeproteins; Histamine H2 Antagonists; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Ranitidine; Rats; Rats, Wistar; Superoxides

1992
Pharmacological characterization of histamine H3 receptors in isolated rabbit gastric glands.
    The American journal of physiology, 1992, Volume: 262, Issue:1 Pt 1

    Topics: Aminopyrine; Animals; Carbachol; Gastric Mucosa; Histamine; Histamine Release; In Vitro Techniques; Male; Methylhistamines; Piperidines; Rabbits; Ranitidine; Receptors, Histamine H1

1992
Pharmacological agents of gastric acid secretion: receptor antagonists and pump inhibitors.
    Methods in enzymology, 1990, Volume: 191

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Carbachol; Carbon Radioisotopes; Cell Separation; Cimetidine; Epithelial Cells; Epithelium; Gastric Acid; Gastric Mucosa; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Histamine; Male; Models, Biological; Omeprazole; Parietal Cells, Gastric; Pepsinogens; Radioisotope Dilution Technique; Ranitidine; Rats; Receptors, Cell Surface

1990
[14C]-aminopyrine accumulation by isolated human parietal cells.
    Pharmacology, 1986, Volume: 32, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aminopyrine; Carbachol; Female; Histamine; Humans; In Vitro Techniques; Male; Mast Cells; Middle Aged; Parietal Cells, Gastric; Pentagastrin; Ranitidine; Temperature; Time Factors

1986
Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Adenosine Triphosphatases; Amines; Aminopyrine; Animals; Benzothiazoles; Benzoxazoles; Bucladesine; Chemical Phenomena; Chemistry; Cimetidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Ligation; Male; Omeprazole; Parietal Cells, Gastric; Pyloric Antrum; Ranitidine; Rats; Structure-Activity Relationship; Thiazoles

1988
[Isolated human gastric mucosa cells--studies on physiologic and pharmacologic regulatory mechanisms].
    Klinische Wochenschrift, 1986, Jan-02, Volume: 64, Issue:1

    Topics: Adenylyl Cyclases; Adult; Aged; Aminopyrine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Humans; Intrinsic Factor; Microscopy, Electron; Middle Aged; Parietal Cells, Gastric; Prostaglandins; Ranitidine; Thiazoles

1986
H+ production by isolated cells from human gastric mucosa.
    Agents and actions, 1985, Volume: 16, Issue:3-4

    Topics: Adult; Aged; Aminopyrine; Bucladesine; Carbachol; Cell Fractionation; Dose-Response Relationship, Drug; Female; Gastric Acid; Gastric Mucosa; Histamine; Humans; In Vitro Techniques; Intrinsic Factor; Male; Middle Aged; Ranitidine

1985
Inhibition of acid formation by epidermal growth factor in the isolated rabbit gastric glands.
    The Journal of physiology, 1986, Volume: 378

    Topics: Aminopyrine; Animals; Bucladesine; Depression, Chemical; Dinoprostone; Epidermal Growth Factor; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Male; Omeprazole; Parietal Cells, Gastric; Potassium; Prostaglandins E; Rabbits; Ranitidine

1986
Effect of cimetidine and ranitidine on the metabolism and toxicity of hexamethylmelamine.
    Cancer treatment reports, 1986, Volume: 70, Issue:12

    Topics: Altretamine; Aminopyrine; Animals; Carbon Dioxide; Cimetidine; Male; Microsomes, Liver; Ranitidine; Rats; Rats, Inbred Strains; Triazines

1986
The influence of ranitidine on the pharmacokinetics and toxicity of doxorubicin in rabbits.
    Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:4

    Topics: Aminopyrine; Animals; Breath Tests; Cimetidine; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Female; Metabolic Clearance Rate; Microsomes, Liver; Rabbits; Ranitidine

1988
Effects of hormones (calcitonin, GIP) and pharmacological antagonists (ranitidine and famotidine) on isolated rat parietal cells.
    Regulatory peptides, 1985, Nov-28, Volume: 12, Issue:4

    Topics: Adenylyl Cyclases; Aminopyrine; Animals; Calcitonin; Cell Separation; Dose-Response Relationship, Drug; Famotidine; Gastric Inhibitory Polypeptide; Parietal Cells, Gastric; Ranitidine; Rats; Thiazoles

1985
Inhibition of microsomal drug metabolism by histamine H2-receptor antagonists studied in vivo and in vitro in rodents.
    Gastroenterology, 1982, Volume: 82, Issue:1

    Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Breath Tests; Cimetidine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Furans; Guanidines; Histamine H2 Antagonists; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles; Time Factors

1982
The effects of H2 receptor antagonists on hepatic drug metabolism.
    Scandinavian journal of gastroenterology. Supplement, 1981, Volume: 69

    Topics: Adult; Aminopyrine; Antipyrine; Breath Tests; Cimetidine; Furans; Guanidines; Histamine H2 Antagonists; Humans; Liver; Middle Aged; Ranitidine; Structure-Activity Relationship

1981
Studies on the properties of 3-N-[3-[3-(1-piperidinomethyl)phenoxy]-propyl]amino-4-amino-1,2, 5-thiadiazole-1-oxide (L-643,441) as an H2-receptor antagonist in isolated gastric glands.
    European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2

    Topics: Aminopyrine; Animals; Bucladesine; Exocrine Glands; Gastric Mucosa; Histamine H2 Antagonists; In Vitro Techniques; Male; Rabbits; Ranitidine; Thiadiazoles

1984
Direct gastrin action on isolated rat parietal cells induces morphological transformations.
    Biochimica et biophysica acta, 1993, Feb-17, Volume: 1175, Issue:3

    Topics: Aminopyrine; Animals; Gastrins; Glucose; Histamine; Male; Parietal Cells, Gastric; Ranitidine; Rats; Rats, Sprague-Dawley; Signal Transduction

1993
Effect of N alpha-methyl-histamine on acid secretion in isolated cultured rabbit parietal cells: implications for Helicobacter pylori associated gastritis and gastric physiology.
    Gut, 1997, Volume: 40, Issue:1

    Topics: Aminopyrine; Animals; Carbachol; Carbon Radioisotopes; Cells, Cultured; Colforsin; Gastric Acid; Histamine H2 Antagonists; Methylhistamines; Parasympathomimetics; Parietal Cells, Gastric; Rabbits; Ranitidine; Receptors, Histamine H2

1997
Effect of PACAP-27 on 14C-aminopyrine accumulation in isolated rabbit parietal cells.
    Peptides, 1998, Volume: 19, Issue:6

    Topics: Aminopyrine; Animals; Carbachol; Cells, Cultured; Histamine; Neuropeptides; Neurotransmitter Agents; Parietal Cells, Gastric; Pituitary Adenylate Cyclase-Activating Polypeptide; Rabbits; Ranitidine; Vasoactive Intestinal Peptide

1998
Histamine H2-receptor antagonism of T-593, an anti-ulcer agent: studies on aminopyrine accumulation in isolated canine gastric mucosal cells.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:3

    Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Bucladesine; Carbachol; Carbon Radioisotopes; Cholinergic Agonists; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Guanidines; Histamine; Histamine H2 Antagonists; Omeprazole; Pentagastrin; Pirenzepine; Ranitidine; Sulfones

1998
PACAP stimulates gastric acid secretion in the rat by inducing histamine release.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Deoxyglucose; Gastric Acid; Gastric Fistula; Gastric Mucosa; Histamine H2 Antagonists; Histamine Release; Humans; In Vitro Techniques; Neuropeptides; Neurotransmitter Agents; Parietal Cells, Gastric; Perfusion; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Ranitidine; Rats; Stomach

2001